Experiment set28IT013 for Pseudomonas putida KT2440

Compare to:

Nicotinic Acid nitrogen source

200 most important genes:

  gene name fitness t score description  
PP_0292 -5.6 -5.4 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
PP_0691 -5.5 -6.6 Glutamate 5-kinase compare
PP_5076 -4.3 -24.1 L-glutamate synthase(NADPH) alpha subunit compare
PP_0082 -4.1 -7.7 tryptophan synthase alpha chain compare
PP_5075 -3.8 -17.0 glutamate synthase (NADPH) beta subunit compare
PP_4724 -3.8 -13.7 Carbamoyl-phosphate synthase small chain compare
PP_4890 -3.7 -6.8 ATP phosphoribosyltransferase regulatory subunit compare
PP_0083 -3.7 -8.1 tryptophan synthase beta chain compare
PP_0293 -3.7 -2.7 Imidazole glycerol phosphate synthase subunit HisF compare
PP_4909 -3.6 -12.5 phosphoserine phosphatase compare
PP_4723 -3.6 -26.8 Carbamoyl-phosphate synthase large chain compare
PP_1985 -3.5 -7.1 3-isopropylmalate dehydratase large subunit compare
PP_1988 -3.5 -10.7 3-isopropylmalate dehydrogenase compare
PP_0290 -3.5 -9.5 Imidazole glycerol phosphate synthase subunit HisH compare
PP_3511 -3.5 -13.4 Branched-chain-amino-acid aminotransferase compare
PP_4680 -3.4 -17.3 acetohydroxybutanoate synthase / acetolactate synthase compare
PP_5014 -3.4 -4.6 Phosphoribosyl-AMP cyclohydrolase compare
PP_4678 -3.4 -19.1 Ketol-acid reductoisomerase compare
PP_0966 -3.3 -12.7 Histidinol dehydrogenase compare
PP_0422 -3.2 -8.8 Indole-3-glycerol phosphate synthase compare
PP_0289 -3.2 -9.1 Imidazoleglycerol-phosphate dehydratase compare
PP_5128 -3.2 -8.5 Dihydroxy-acid dehydratase compare
PP_0421 -3.2 -8.3 Anthranilate phosphoribosyltransferase compare
PP_1995 -3.2 -11.1 N-(5'-phosphoribosyl)anthranilate isomerase compare
PP_1986 -3.1 -6.3 3-isopropylmalate dehydratase small subunit compare
PP_5098 -3.1 -10.0 methionine biosynthesis protein MetW compare
PP_0967 -3.1 -13.2 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
PP_1088 -3.1 -14.4 Argininosuccinate synthase compare
PP_4999 -3.1 -3.1 dihydroorotase-like protein compare
PP_0417 -3.0 -17.9 Anthranilate synthase component 1 compare
PP_0965 -3.0 -13.2 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
PP_4058 -3.0 -15.4 1,4-alpha-glucan branching enzyme compare
PP_0420 -2.9 -13.0 aminodeoxychorismate synthase / para-aminobenzoate synthase multi-enzyme complex compare
PP_0184 -2.9 -8.9 Argininosuccinate lyase compare
PP_4679 -2.8 -10.1 acetohydroxybutanoate synthase / acetolactate synthase compare
PP_5097 -2.8 -15.0 homoserine O-acetyltransferase compare
PP_5155 -2.7 -3.7 D-3-phosphoglycerate dehydrogenase / alpha-ketoglutarate reductase compare
PP_5048 -2.7 -7.9 two-component system DNA-binding transcriptional dual regulator GlnL/GlnG compare
PP_1294 -2.6 -4.9 molybdopterin synthase large subunit compare
PP_1079 -2.6 -7.7 Ornithine carbamoyltransferase compare
PP_2001 -2.6 -12.9 O-succinylhomoserine sulfhydrylase compare
PP_1025 -2.5 -11.7 2-isopropylmalate synthase compare
PP_0339 -2.5 -6.1 Pyruvate dehydrogenase E1 component compare
PP_5185 -2.5 -7.7 acetylglutamate kinase-like protein (regulatory domain)/amino acid N-acetyltransferase compare
PP_2370 -2.4 -3.9 conserved protein of unknown function compare
PP_5015 -2.4 -5.6 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
PP_5289 -2.4 -4.9 Acetylglutamate kinase compare
PP_1215 -2.3 -1.5 Crossover junction endodeoxyribonuclease RuvC compare
PP_0291 -2.3 -2.5 conserved protein of unknown function compare
PP_0735 -2.2 -2.5 molybdopterin-synthase adenylyltransferase compare
PP_4799 -2.2 -1.5 putative Muramoyltetrapeptide carboxypeptidase compare
PP_2371 -2.2 -7.0 Sulphite reductase hemoprotein, beta subunit compare
PP_2328 -2.2 -7.6 Phosphoadenosine phosphosulfate reductase compare
PP_3999 -2.1 -6.7 Uroporphyrinogen-III C-methyltransferase/Precorrin-2 dehydrogenase/Sirohydrochlorin ferrochelatase compare
PP_2414 -2.1 -2.4 conserved exported protein of unknown function compare
PP_1110 -2.0 -5.1 serine acetyltransferase compare
PP_4828 -2.0 -2.5 Precorrin-8X methylmutase compare
PP_0846 -1.9 -2.0 DnaK-like molecular chaperone specific for IscU compare
PP_5303 -1.9 -6.5 aminoacrylate/iminopropionate hydrolase/deaminase compare
PP_5047 -1.8 -5.3 two-component system sensory histidine kinase/phosphatase GlnL/GlnG compare
PP_2327 -1.8 -9.8 transcriptional dual regulator / CysB-O-acetyl-L-serine compare
PP_3941 -1.8 -8.0 maleamate amidohydrolase compare
PP_0164 -1.7 -8.9 conserved protein of unknown function compare
PP_1292 -1.7 -6.3 Cyclic pyranopterin monophosphate synthase accessory protein compare
PP_1912 -1.7 -6.9 Phosphate acyltransferase compare
PP_3942 -1.7 -6.8 maleate isomerase compare
PP_0625 -1.6 -9.0 Chaperone protein ClpB compare
PP_3945 -1.6 -10.5 2,5-dihydroxypyridine 5,6-dioxygenase compare
PP_1293 -1.6 -1.8 molybdopterin synthase small subunit compare
PP_3943 -1.6 -8.5 N-formylmaleamate deformylase compare
PP_4364 -1.6 -5.6 putative Anti-sigma F factor antagonist compare
PP_2168 -1.6 -9.4 Transaldolase compare
PP_3829 -1.6 -5.5 Molybdenum transport system permease protein ModB compare
PP_3828 -1.5 -6.7 Molybdate-binding periplasmic protein compare
PP_1589 -1.5 -8.8 uridylyltransferase compare
PP_1216 -1.5 -1.9 Holliday junction ATP-dependent DNA helicase RuvA compare
PP_0719 -1.5 -1.4 ribosome-associated potassium-dependent informational ATP/GTPase compare
PP_1109 -1.5 -9.0 Transcriptional regulator, GntR family compare
PP_5227 -1.4 -7.8 diaminopimelate decarboxylase compare
PP_3484 -1.4 -6.8 Response regulator receiver protein compare
PP_2390 -1.4 -7.6 Transcriptional regulator, LysR family compare
PP_3948 -1.4 -10.7 nicotinate dehydrogenase subunit B (EC 1.17.2.1) (from data) compare
PP_3830 -1.4 -8.7 Molybdenum import ATP-binding protein ModC compare
PP_4696 -1.4 -5.3 Nitrogen regulation protein NR(I) compare
PP_3944 -1.3 -6.2 6-hydroxynicotinate 3-monooxygenase compare
PP_3947 -1.3 -4.6 nicotinate dehydrogenase subunit A compare
PP_0127 -1.3 -8.3 Thiol:disulfide interchange protein compare
PP_5322 -1.3 -6.7 putative metal ion transporter compare
PP_2388 -1.3 -3.9 Transporter, LysE family compare
PP_1233 -1.2 -4.1 sulfurtransferase compare
PP_2123 -1.2 -6.5 molybdenum::molybdopterin ligase compare
PP_4726 -1.2 -4.4 Chaperone protein DnaJ compare
PP_0401 -1.2 -1.7 Ribosomal RNA small subunit methyltransferase A compare
PP_4004 -1.1 -2.3 DNA translocase FtsK compare
PP_1994 -1.1 -2.2 tRNA pseudouridine (38-40)synthase compare
PP_1022 -1.1 -4.4 glucose 6-phosphate-1-dehydrogenase compare
PP_4789 -1.1 -3.8 heat shock protein, Co2+ and Mg2+ efflux protein compare
PP_1111 -1.1 -3.1 putative Synthetase compare
PP_4943 -1.0 -2.2 putative Glycosyl transferase compare
PP_0914 -1.0 -6.1 GGDEF domain protein compare
PP_1217 -1.0 -2.6 Holliday junction ATP-dependent DNA helicase RuvB compare
PP_5095 -1.0 -1.2 pyrroline-5-carboxylate reductase compare
PP_2899 -1.0 -2.5 conserved exported protein of unknown function compare
PP_2820 -0.9 -2.9 HTH-type transcriptional regulator nfxB compare
PP_0833 -0.9 -2.7 queuine tRNA-ribosyltransferase compare
PP_3821 -0.9 -6.3 UTP-glucose-1-phosphate uridylyltransferase compare
PP_0949 -0.9 -3.6 putative ATP-binding protein UPF0042 compare
PP_3892 -0.9 -2.1 conserved protein of unknown function compare
PP_4231 -0.8 -4.7 putative Xanthine dehydrogenase accessory factor compare
PP_5652 -0.8 -2.3 conserved protein of unknown function, phage origin compare
PP_0232 -0.8 -1.2 ATP-binding taurine transporter subunit compare
PP_4964 -0.8 -1.4 D-erythrose 4-phosphate dehydrogenase compare
PP_2307 -0.8 -2.7 conserved protein of unknown function compare
PP_2070 -0.8 -1.6 Transcriptional regulator, AraC family compare
PP_2402 -0.8 -1.7 putative Sensor histidine kinase compare
PP_3940 -0.8 -4.9 Putative metabolite transport protein NicT compare
PP_4895 -0.8 -2.4 tRNA dimethylallyltransferase compare
PP_4296 -0.8 -2.0 conserved exported protein of unknown function compare
PP_5202 -0.8 -1.9 putative cell division protein compare
PP_4829 -0.8 -3.0 putative precorrin-3B synthase compare
PP_4880 -0.8 -3.8 exoribonuclease R compare
PP_4320 -0.8 -3.6 cytochrome c-type biogenesis protein compare
PP_2378 -0.8 -0.9 Fe/S biogenesis protein NfuA compare
PP_4099 -0.7 -7.0 two-componenent system BarA/UvrY - regulatory subunit compare
PP_2088 -0.7 -2.8 RNA polymerase sigma factor SigX compare
PP_4681 -0.7 -1.9 conserved protein of unknown function compare
PP_5583 -0.7 -1.3 conserved protein of unknown function compare
PP_1322 -0.7 -1.5 putative Lipoprotein compare
PP_1650 -0.7 -6.2 Sensor protein GacS compare
PP_1493 -0.7 -2.2 chemotaxis response regulator protein-glutamate methylesterase of group 3 operon compare
PP_4340 -0.7 -3.2 response regulator for chemotactic signal transduction compare
PP_4363 -0.7 -5.0 Sensor histidine kinase/response regulator compare
PP_4338 -0.7 -4.1 Chemotaxis histidine kinase CheA compare
PP_1598 -0.7 -4.0 regulatory intramembrane protein RIP zinc protease compare
PP_1734 -0.7 -0.8 Probable septum site-determining protein MinC compare
PP_3590 -0.7 -3.5 aromatic-amino-acid transaminase (EC 2.6.1.57) (from data) compare
PP_4910 -0.7 -1.2 conserved protein of unknown function compare
PP_3508 -0.7 -2.2 Protein CobW compare
PP_4143 -0.7 -2.6 conserved protein of unknown function compare
PP_5533 -0.7 -1.3 conserved protein of unknown function compare
PP_5233 -0.7 -4.5 ammonium transporter AmtB compare
PP_3411 -0.6 -1.2 conserved protein of unknown function compare
PP_4504 -0.6 -1.6 conserved exported protein of unknown function compare
PP_2653 -0.6 -2.0 Transcriptional regulator, Cro/CI family compare
PP_2217 -0.6 -2.2 enoyl-CoA hydratase compare
PP_1656 -0.6 -4.4 ATP:GTP 3'-pyrophosphotransferase compare
PP_1876 -0.6 -2.6 putative ATP/GTP-binding protein of the AAA+ family compare
PP_1346 -0.6 -2.4 Glutamate N-acetyltransferase/Amino-acid acetyltransferase compare
PP_1683 -0.6 -1.8 Transcriptional regulator, MarR family compare
PP_1147 -0.6 -2.7 conserved protein of unknown function compare
PP_0066 -0.6 -2.6 Ribosomal RNA small subunit methyltransferase B compare
PP_1568 -0.6 -1.1 conserved protein of unknown function compare
PP_2322 -0.6 -4.2 Major outer membrane lipoprotein compare
PP_1654 -0.6 -1.4 cysteine synthase B compare
PP_t10 -0.6 -1.8 tRNA-Pro compare
PP_4695 -0.6 -4.6 Sensory box histidine kinase compare
PP_2302 -0.6 -2.0 DNA-binding, ATP-dependent protease compare
PP_1979 -0.6 -2.3 putative Hydrolase compare
PP_0065 -0.6 -1.7 NAD-binding component of TrK potassium transporter compare
PP_1353 -0.6 -0.5 conserved membrane protein of unknown function compare
PP_5571 -0.6 -1.0 conserved protein of unknown function compare
PP_4480 -0.6 -4.0 arginine N-succinyltransferase, subunit alpha compare
PP_5328 -0.6 -1.6 putative phosphate transport system permease protein compare
PP_0610 -0.6 -1.6 conserved exported protein of unknown function compare
PP_1224 -0.6 -3.0 periplasmic subunit of the TolQRA transport system compare
PP_0980 -0.5 -2.7 Probable cytosol aminopeptidase compare
PP_3662 -0.5 -3.7 conserved protein of unknown function compare
PP_5430 -0.5 -2.4 protein of unknown function compare
PP_5552 -0.5 -1.9 conserved protein of unknown function compare
PP_4804 -0.5 -1.4 RlpA-like lipoprotein compare
PP_1004 -0.5 -1.1 conserved protein of unknown function compare
PP_3757 -0.5 -1.7 Chemotaxis protein CheY compare
PP_0425 -0.5 -1.3 conserved protein of unknown function compare
PP_2214 -0.5 -2.2 3-hydroxyacyl-CoA dehydrogenase type-2 compare
PP_3380 -0.5 -2.0 2-ketogluconate utilization repressor compare
PP_2459 -0.5 -1.8 ribose pyranase compare
PP_1300 -0.5 -2.1 putative amino acid ABC transporter - ATP-binding subunit compare
PP_0919 -0.5 -2.7 conserved protein of unknown function compare
PP_2624 -0.5 -2.2 conserved protein of unknown function compare
PP_2136 -0.5 -1.9 enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase compare
PP_4848 -0.5 -2.1 Curved DNA-binding protein compare
PP_1186 -0.5 -1.9 two component system DNA-binding transcriptional dual regulator compare
PP_5456 -0.5 -0.7 conserved protein of unknown function compare
PP_2177 -0.5 -2.8 putative transcriptional regulator compare
PP_4532 -0.5 -1.6 ATP-dependent DEAD-box RNA helicase require for 50S ribosomal subunit biogenesis compare
PP_1999 -0.5 -1.2 membrane protein required for colicin V production compare
PP_5519 -0.5 -1.6 conserved protein of unknown function of phage origin compare
PP_0832 -0.5 -2.4 S-adenosylmethionine:tRNA ribosyltransferase-isomerase compare
PP_4162 -0.5 -2.4 conserved membrane protein of unknown function compare
PP_4879 -0.5 -1.9 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB compare
PP_0274 -0.5 -1.2 putative transcriptional regulator containing HTH domain compare
PP_1677 -0.5 -2.4 Adenosyl-cobyric acid synthase compare
PP_0900 -0.5 -1.5 PAP2 family protein compare
PP_0888 -0.5 -1.2 Photosynthetic apparatus regulatory protein RegA compare
PP_5619 -0.5 -2.0 protein of unknown function compare
PP_5471 -0.5 -1.1 putative response regulator receiver protein compare
PP_4937 -0.5 -0.9 toluene tolerance protein compare
PP_5073 -0.5 -1.1 conserved exported protein of unknown function compare
PP_4738 -0.5 -1.9 conserved exported protein of unknown function compare
PP_2960 -0.5 -1.9 transcriptional regulator, AraC family compare


Specific Phenotypes

For 11 genes in this experiment

For nitrogen source Nicotinic Acid in Pseudomonas putida KT2440

For nitrogen source Nicotinic Acid across organisms