Experiment set28IT007 for Escherichia coli BW25113

Compare to:

LB_plus_SM_buffer

200 most important genes:

  gene name fitness t score description  
b1361 ydaW -3.1 -1.3 orf, hypothetical protein (VIMSS) compare
b2330 yfcB -2.6 -3.0 putative adenine-specific methylase (VIMSS) compare
b3979 thrT -2.2 -0.9 tRNA-Thr (NCBI) compare
b4042 dgkA -2.1 -3.5 diacylglycerol kinase (NCBI) compare
b2528 iscA -1.9 -2.3 iron-sulfur cluster assembly protein (NCBI) compare
b3390 aroK -1.9 -3.1 shikimate kinase I (NCBI) compare
b3816 corA -1.8 -10.1 magnesium/nickel/cobalt transporter (NCBI) compare
b3290 trkA -1.7 -2.9 potassium transporter peripheral membrane component (NCBI) compare
b3636 rpmG -1.7 -3.3 50S ribosomal protein L33 (NCBI) compare
b2567 rnc -1.7 -1.5 ribonuclease III (NCBI) compare
b3870 glnA -1.6 -4.0 glutamine synthetase (NCBI) compare
b2846 yqeH -1.6 -1.1 orf, hypothetical protein (VIMSS) compare
b4701 sokX -1.6 -1.3 sok-related sRNA, function unknown (RefSeq) compare
b2279 nuoK -1.6 -1.7 NADH dehydrogenase subunit K (NCBI) compare
b3863 polA -1.6 -1.5 DNA polymerase I (NCBI) compare
b3706 trmE -1.5 -5.7 tRNA modification GTPase (NCBI) compare
b4171 miaA -1.5 -4.1 tRNA delta(2)-isopentenylpyrophosphate transferase (NCBI) compare
b4603 rseX -1.5 -1.2 sRNA regulating ompA and ompC translation, with Hfq (RefSeq) compare
b1861 ruvA -1.5 -2.0 Holliday junction DNA helicase motor protein (NCBI) compare
b2282 nuoH -1.3 -4.3 NADH dehydrogenase subunit H (NCBI) compare
b0740 tolB -1.3 -5.4 translocation protein TolB precursor (NCBI) compare
b2934 cmtB -1.2 -0.8 predicted mannitol-specific enzyme IIA component of PTS (NCBI) compare
b0737 tolQ -1.2 -3.2 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b0683 fur -1.2 -1.9 ferric uptake regulator (NCBI) compare
b1351 racC -1.2 -0.8 Rac prophage; predicted protein (NCBI) compare
b3613 yibP -1.2 -4.8 putative membrane protein (VIMSS) compare
b2498 upp -1.2 -3.6 uracil phosphoribosyltransferase (VIMSS) compare
b3026 qseC -1.2 -4.5 sensory histidine kinase in two-component regulatory system with QseB (NCBI) compare
b0990 cspG -1.2 -1.4 DNA-binding transcriptional regulator (NCBI) compare
b1860 ruvB -1.2 -1.0 Holliday junction DNA helicase B (NCBI) compare
b2699 recA -1.1 -1.3 recombinase A (NCBI) compare
b2912 ygfA -1.1 -3.2 putative ligase (VIMSS) compare
b3839 tatC -1.1 -6.6 TatABCE protein translocation system subunit (NCBI) compare
b3741 gidA -1.0 -4.4 glucose-inhibited division protein A (NCBI) compare
b1236 galU -1.0 -4.3 glucose-1-phosphate uridylyltransferase (NCBI) compare
b0222 lpcA -1.0 -2.5 phosphoheptose isomerase (NCBI) compare
b4177 purA -1.0 -1.1 adenylosuccinate synthetase (NCBI) compare
b0890 ftsK -1.0 -4.4 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b2277 nuoM -1.0 -5.1 NADH dehydrogenase subunit M (NCBI) compare
b2620 smpB -1.0 -1.6 SsrA-binding protein (NCBI) compare
b3629 rfaS -1.0 -3.6 lipopolysaccharide core biosynthesis protein (NCBI) compare
b4676 yoaK -1.0 -0.7 expressed protein (RefSeq) compare
b1847 yebF -1.0 -1.5 predicted protein (RefSeq) compare
b3162 deaD -1.0 -4.3 inducible ATP-independent RNA helicase (VIMSS) compare
b3728 pstS -1.0 -3.0 phosphate transporter subunit (NCBI) compare
b1165 ymgA -0.9 -0.8 hypothetical protein (NCBI) compare
b2820 recB -0.9 -1.2 exonuclease V (RecBCD complex), beta subunit (NCBI) compare
b1409 ynbB -0.9 -1.2 predicted CDP-diglyceride synthase (NCBI) compare
b2935 tktA -0.9 -1.7 transketolase 1, thiamin-binding (NCBI) compare
b1257 yciE -0.9 -0.6 hypothetical protein (NCBI) compare
b1363 trkG -0.9 -0.6 Rac prophage; potassium transporter subunit (NCBI) compare
b0739 tolA -0.9 -3.0 cell envelope integrity inner membrane protein TolA (NCBI) compare
b3035 tolC -0.9 -6.3 outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes (VIMSS) compare
b4647 mokA -0.9 -0.8 no description compare
b3790 rffC -0.9 -5.2 TDP-fucosamine acetyltransferase (RefSeq) compare
b4179 vacB -0.9 -5.2 putative enzyme (VIMSS) compare
b1182 hlyE -0.9 -0.5 hemolysin E (VIMSS) compare
b4128 yjdK -0.9 -0.6 hypothetical protein (NCBI) compare
b3052 rfaE -0.9 -4.2 fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) compare
b0888 trxB -0.9 -3.0 thioredoxin reductase, FAD/NAD(P)-binding (NCBI) compare
b2808 gcvA -0.9 -4.1 DNA-binding transcriptional dual regulator (NCBI) compare
b1576 ydfD -0.9 -0.5 Qin prophage; predicted protein (NCBI) compare
b1765 ydjA -0.8 -0.9 predicted oxidoreductase (NCBI) compare
b1499 ydeO -0.8 -0.5 predicted DNA-binding transcriptional acfivator (NCBI) compare
b0677 nagA -0.8 -4.5 N-acetylglucosamine-6-phosphate deacetylase (NCBI) compare
b3183 obgE -0.8 -1.3 GTPase involved in cell partioning and DNA repair (NCBI) compare
b2297 pta -0.8 -0.5 phosphate acetyltransferase (NCBI) compare
b1730 ydjO -0.8 -1.2 predicted protein (RefSeq) compare
b0049 apaH -0.8 -2.3 diadenosinetetraphosphatase (NCBI) compare
b2431 b2431 -0.8 -4.9 orf, hypothetical protein (VIMSS) compare
b1290 sapF -0.8 -1.7 predicted antimicrobial peptide transporter subunit (NCBI) compare
b0630 lipB -0.8 -1.2 protein of lipoate biosynthesis (VIMSS) compare
b0161 degP -0.8 -4.8 serine endoprotease (protease Do), membrane-associated (NCBI) compare
b1497 b1497 -0.8 -0.5 putative enzyme (VIMSS) compare
b2340 sixA -0.8 -3.2 phosphohistidine phosphatase (NCBI) compare
b1726 yniB -0.8 -2.3 predicted inner membrane protein (NCBI) compare
b0658 ybeX -0.8 -0.7 predicteed ion transport (NCBI) compare
b2576 srmB -0.8 -2.5 ATP-dependent RNA helicase (NCBI) compare
b3621 rfaC -0.8 -4.0 ADP-heptose:LPS heptosyl transferase I (NCBI) compare
b0738 tolR -0.8 -2.4 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b1129 phoQ -0.8 -1.6 sensory histidine kinase in two-compoent regulatory system with PhoP (NCBI) compare
b2283 nuoG -0.8 -4.3 NADH:ubiquinone oxidoreductase, chain G (RefSeq) compare
b2504 yfgG -0.8 -1.3 Negative regulator of nickel and cobalt uptake (YfgG) (from data) compare
b1192 ldcA -0.8 -3.6 L,D-carboxypeptidase A (NCBI) compare
b3792 wzxE -0.7 -5.0 O-antigen translocase (NCBI) compare
b1130 phoP -0.7 -0.9 DNA-binding response regulator in two-component regulatory system with PhoQ (NCBI) compare
b2278 nuoL -0.7 -5.0 NADH dehydrogenase subunit L (NCBI) compare
b4685 yrbN -0.7 -2.2 expressed protein (RefSeq) compare
b3229 sspA -0.7 -2.6 stringent starvation protein A (NCBI) compare
b1612 fumA -0.7 -2.9 fumarate hydratase (fumarase A), aerobic Class I (NCBI) compare
b4163 glyV -0.7 -1.3 tRNA-Gly (NCBI) compare
b1551 b1551 -0.7 -0.4 orf, hypothetical protein (VIMSS) compare
b3181 greA -0.7 -4.2 transcription elongation factor: cleaves 3' nucleotide of paused mRNA (VIMSS) compare
b1258 yciF -0.7 -0.9 hypothetical protein (NCBI) compare
b4453 ldrD -0.7 -1.1 toxic polypeptide, small (NCBI) compare
b4146 yjeK -0.7 -1.8 predicted lysine aminomutase (NCBI) compare
b3778 rep -0.7 -4.5 DNA helicase and single-stranded DNA-dependent ATPase (NCBI) compare
b3642 pyrE -0.7 -3.1 orotate phosphoribosyltransferase (NCBI) compare
b1121 ycfZ -0.7 -1.5 predicted inner membrane protein (NCBI) compare
b1536 ydeI -0.7 -0.9 hypothetical protein (NCBI) compare
b2911 ssrS -0.7 -1.7 6S regulatory RNA (NCBI) compare
b0200 gmhB -0.7 -1.3 hypothetical protein (NCBI) compare
b1307 pspD -0.7 -1.7 peripheral inner membrane phage-shock protein (NCBI) compare
b1001 yccE -0.7 -0.4 hypothetical protein (NCBI) compare
b2280 nuoJ -0.7 -3.7 NADH dehydrogenase subunit J (NCBI) compare
b1347 ydaC -0.7 -0.3 Rac prophage; predicted protein (NCBI) compare
b1545 pinQ -0.7 -0.2 Qin prophage; predicted site-specific recombinase (NCBI) compare
b2822 recC -0.7 -3.6 exonuclease V (RecBCD complex), gamma chain (NCBI) compare
b4481 rffT -0.7 -4.6 4-alpha-L-fucosyltransferase (NCBI) compare
b3726 pstA -0.7 -3.6 phosphate transporter subunit (NCBI) compare
b3962 udhA -0.7 -3.8 putative oxidoreductase (VIMSS) compare
b1293 sapB -0.7 -1.4 predicted antimicrobial peptide transporter subunit (NCBI) compare
b3238 yhcN -0.7 -1.9 orf, hypothetical protein (VIMSS) compare
b0439 lon -0.7 -3.2 DNA-binding ATP-dependent protease La (NCBI) compare
b1658 purR -0.7 -3.0 DNA-binding transcriptional repressor, hypoxanthine-binding (NCBI) compare
b2569 lepA -0.7 -3.0 GTP-binding protein LepA (NCBI) compare
b0928 aspC -0.7 -3.9 aspartate aminotransferase, PLP-dependent (NCBI) compare
b0706 ybfD -0.7 -1.3 hypothetical protein (NCBI) compare
b1040 csgD -0.7 -1.2 DNA-binding transcriptional activator in two-component regulatory system (NCBI) compare
b4596 yciZ -0.6 -1.1 hypothetical protein (RefSeq) compare
b2501 ppk -0.6 -4.4 polyphosphate kinase (NCBI) compare
b2564 pdxJ -0.6 -2.5 pyridoxal phosphate biosynthetic protein (NCBI) compare
b2352 yfdI -0.6 -0.7 CPS-53 (KpLE1) prophage; predicted inner membrane protein (NCBI) compare
b0014 dnaK -0.6 -1.6 molecular chaperone DnaK (NCBI) compare
b0142 folK -0.6 -0.6 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase (NCBI) compare
b1642 slyA -0.6 -1.7 transcriptional regulator for cryptic hemolysin (VIMSS) compare
b1334 fnr -0.6 -1.8 DNA-binding transcriptional dual regulator, global regulator of anaerobic growth (NCBI) compare
b2284 nuoF -0.6 -3.1 NADH:ubiquinone oxidoreductase, chain F (NCBI) compare
b0722 sdhD -0.6 -3.2 succinate dehydrogenase cytochrome b556 small membrane subunit (NCBI) compare
b4497 yeeL -0.6 -0.8 no description compare
b0724 sdhB -0.6 -4.3 succinate dehydrogenase, FeS subunit (NCBI) compare
b2175 spr -0.6 -2.7 predicted peptidase, outer membrane lipoprotein (NCBI) compare
b3631 rfaG -0.6 -5.3 glucosyltransferase I (NCBI) compare
b0114 aceE -0.6 -0.8 pyruvate dehydrogenase subunit E1 (NCBI) compare
b4178 yjeB -0.6 -3.5 predicted DNA-binding transcriptional regulator (NCBI) compare
b1762 b1762 -0.6 -2.0 orf, hypothetical protein (VIMSS) compare
b4375 prfC -0.6 -2.6 peptide chain release factor 3 (NCBI) compare
b0471 ybaB -0.6 -2.2 hypothetical protein (NCBI) compare
b2659 b2659 -0.6 -1.2 orf, hypothetical protein (VIMSS) compare
b3791 rffA -0.6 -4.2 TDP-4-oxo-6-deoxy-D-glucose transaminase (NCBI) compare
b1175 minD -0.6 -3.5 membrane ATPase of the MinC-MinD-MinE system (NCBI) compare
b0506 allR -0.6 -3.2 DNA-binding transcriptional repressor (NCBI) compare
b1853 yebK -0.6 -2.5 predicted DNA-binding transcriptional regulator (NCBI) compare
b0145 dksA -0.6 -2.2 DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) compare
b3842 rfaH -0.6 -3.4 transcriptional activator RfaH (NCBI) compare
b1159 mcrA -0.6 -0.9 e14 prophage; 5-methylcytosine-specific restriction endonuclease B (NCBI) compare
b2066 udk -0.6 -2.4 uridine/cytidine kinase (VIMSS) compare
b1627 rsxA -0.6 -1.9 Na(+)-translocating NADH-quinone reductase subunit E (NCBI) compare
b3169 nusA -0.6 -1.9 transcription elongation factor NusA (NCBI) compare
b2286 nuoC -0.6 -2.9 NADH:ubiquinone oxidoreductase, chain C,D (RefSeq) compare
b0912 ihfB -0.6 -2.6 integration host factor subunit beta (NCBI) compare
b1882 cheY -0.6 -0.4 chemotaxis regulator transmitting signal to flagellar motor component (NCBI) compare
b1656 sodB -0.6 -2.1 superoxide dismutase, Fe (NCBI) compare
b4203 rplI -0.6 -2.9 50S ribosomal protein L9 (NCBI) compare
b1691 ydiN -0.6 -2.5 predicted transporter (RefSeq) compare
b3844 fre -0.6 -3.2 NAD(P)H-flavin reductase (NCBI) compare
b3786 rffE -0.6 -4.9 UDP-N-acetyl glucosamine-2-epimerase (NCBI) compare
b1865 nudB -0.6 -1.1 dATP pyrophosphohydrolase (NCBI) compare
b2136 yohD -0.6 -1.5 orf, hypothetical protein (VIMSS) compare
b4413 sokC -0.6 -1.0 regulatory antisense RNA (NCBI) compare
b3119 tdcR -0.6 -1.8 threonine dehydratase operon activator protein (VIMSS) compare
b1167 ymgC -0.6 -0.3 hypothetical protein (NCBI) compare
b4414 tff -0.6 -2.5 unknown RNA (NCBI) compare
b3916 pfkA -0.6 -1.7 6-phosphofructokinase (NCBI) compare
b2285 nuoE -0.6 -1.2 NADH dehydrogenase subunit E (NCBI) compare
b2055 wcaE -0.6 -0.3 predicted glycosyl transferase (NCBI) compare
b0685 ybfE -0.6 -1.2 orf, hypothetical protein (VIMSS) compare
b0705 ybfL -0.6 -0.4 putative receptor protein (VIMSS) compare
b0053 surA -0.6 -3.0 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b1105 ycfM -0.6 -2.3 predicted outer membrane lipoprotein (NCBI) compare
b3784 rfe -0.6 -4.5 UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase (NCBI) compare
b1920 fliY -0.6 -1.8 cystine transporter subunit (NCBI) compare
b0437 clpP -0.6 -2.8 ATP-dependent Clp protease proteolytic subunit (NCBI) compare
b2553 glnB -0.5 -2.6 regulatory protein P-II for glutamine synthetase (NCBI) compare
b2276 nuoN -0.5 -2.9 NADH:ubiquinone oxidoreductase, membrane subunit N (RefSeq) compare
b3781 trxA -0.5 -2.3 thioredoxin 1 (VIMSS) compare
b1286 rnb -0.5 -1.5 exoribonuclease II (NCBI) compare
b3871 bipA -0.5 -4.4 GTP-binding protein (NCBI) compare
b0249 ykfF -0.5 -0.8 CP4-6 prophage; predicted protein (NCBI) compare
b0605 ahpC -0.5 -2.4 alkyl hydroperoxide reductase, C22 subunit (NCBI) compare
b4312 fimB -0.5 -4.2 tyrosine recombinase/inversion of on/off regulator of fimA (NCBI) compare
b1712 ihfA -0.5 -1.2 integration host factor subunit alpha (NCBI) compare
b0082 mraW -0.5 -1.6 S-adenosyl-methyltransferase (NCBI) compare
b2189 proL -0.5 -1.2 tRNA-Pro (NCBI) compare
b0676 nagC -0.5 -3.6 DNA-binding transcriptional dual regulator, repressor of N-acetylglucosamine (NCBI) compare
b2110 yehC -0.5 -0.8 predicted periplasmic pilin chaperone (NCBI) compare
b0059 hepA -0.5 -4.6 ATP-dependent helicase HepA (NCBI) compare
b3977 tyrU -0.5 -0.7 tRNA-Tyr (NCBI) compare
b0862 artQ -0.5 -2.0 arginine transporter subunit (NCBI) compare
b3940 metL -0.5 -3.9 bifunctional aspartate kinase II/homoserine dehydrogenase II (NCBI) compare
b2320 pdxB -0.5 -3.2 erythronate-4-phosphate dehydrogenase (NCBI) compare
b3389 aroB -0.5 -4.2 3-dehydroquinate synthase (NCBI) compare
b1180 ycgM -0.5 -1.7 predicted isomerase/hydrolase (NCBI) compare
b1161 ycgX -0.5 -0.8 hypothetical protein (NCBI) compare
b4006 purH -0.5 -4.1 bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (NCBI) compare
b0523 purE -0.5 -2.2 phosphoribosylaminoimidazole carboxylase catalytic subunit (NCBI) compare
b1279 yciS -0.5 -0.8 conserved inner membrane protein (NCBI) compare
b4201 priB -0.5 -1.6 primosomal replication protein N (NCBI) compare
b1690 ydiM -0.5 -1.4 predicted transporter (NCBI) compare
b3236 mdh -0.5 -3.3 malate dehydrogenase (NCBI) compare


Specific Phenotypes

None in this experiment

For Escherichia coli BW25113 in phage experiments