Experiment set27IT089 for Escherichia coli BW25113

Compare to:

LB in EcoFAB_3.5mL

200 most important genes:

  gene name fitness t score description  
b0149 mrcB -4.8 -32.1 penicillin-binding protein 1b (NCBI) compare
b1192 ldcA -4.8 -9.6 L,D-carboxypeptidase A (NCBI) compare
b1105 ycfM -3.8 -10.6 predicted outer membrane lipoprotein (NCBI) compare
b0740 tolB -3.0 -11.4 translocation protein TolB precursor (NCBI) compare
b3613 yibP -3.0 -11.8 putative membrane protein (VIMSS) compare
b2830 nudH -2.9 -3.7 dinucleoside polyphosphate hydrolase (NCBI) compare
b3778 rep -2.9 -16.0 DNA helicase and single-stranded DNA-dependent ATPase (NCBI) compare
b3169 nusA -2.9 -6.1 transcription elongation factor NusA (NCBI) compare
b2912 ygfA -2.5 -7.3 putative ligase (VIMSS) compare
b3940 metL -2.5 -11.3 bifunctional aspartate kinase II/homoserine dehydrogenase II (NCBI) compare
b3387 dam -2.5 -18.6 DNA adenine methylase (NCBI) compare
b0741 pal -2.4 -7.9 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b1084 rne -2.4 -8.2 fused ribonucleaseE: endoribonuclease/RNA-binding protein/RNA degradosome binding protein (NCBI) compare
b0737 tolQ -2.3 -5.5 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b0739 tolA -2.3 -5.4 cell envelope integrity inner membrane protein TolA (NCBI) compare
b1161 ycgX -2.3 -1.9 hypothetical protein (NCBI) compare
b2281 nuoI -2.2 -5.0 NADH dehydrogenase subunit I (NCBI) compare
b2951 yggS -2.2 -10.5 predicted enzyme (NCBI) compare
b0949 uup -2.1 -13.6 fused predicted transporter subunits of ABC superfamily: ATP-binding components (NCBI) compare
b4651 yibW -2.1 -1.4 no description compare
b4042 dgkA -2.1 -3.8 diacylglycerol kinase (NCBI) compare
b3792 wzxE -2.0 -12.3 O-antigen translocase (NCBI) compare
b3977 tyrU -1.9 -1.3 tRNA-Tyr (NCBI) compare
b2283 nuoG -1.9 -9.7 NADH:ubiquinone oxidoreductase, chain G (RefSeq) compare
b3790 rffC -1.9 -8.7 TDP-fucosamine acetyltransferase (RefSeq) compare
b1865 nudB -1.9 -3.5 dATP pyrophosphohydrolase (NCBI) compare
b0738 tolR -1.8 -5.6 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b3183 obgE -1.8 -2.3 GTPase involved in cell partioning and DNA repair (NCBI) compare
b3463 ftsE -1.8 -1.7 predicted transporter subunit: ATP-binding component of ABC superfamily (NCBI) compare
b3021 ygiT -1.7 -2.9 predicted DNA-binding transcriptional regulator (NCBI) compare
b3791 rffA -1.7 -11.6 TDP-4-oxo-6-deoxy-D-glucose transaminase (NCBI) compare
b2935 tktA -1.7 -2.5 transketolase 1, thiamin-binding (NCBI) compare
b4481 rffT -1.7 -10.4 4-alpha-L-fucosyltransferase (NCBI) compare
b0439 lon -1.7 -7.9 DNA-binding ATP-dependent protease La (NCBI) compare
b3811 xerC -1.7 -3.9 site-specific tyrosine recombinase XerC (NCBI) compare
b1830 prc -1.7 -11.4 carboxy-terminal protease for penicillin-binding protein 3 (NCBI) compare
b1235 rssB -1.7 -9.9 response regulator of RpoS (NCBI) compare
b2567 rnc -1.7 -1.1 ribonuclease III (NCBI) compare
b1850 eda -1.6 -4.0 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (NCBI) compare
b3389 aroB -1.6 -10.4 3-dehydroquinate synthase (NCBI) compare
b1292 sapC -1.6 -2.6 predicted antimicrobial peptide transporter subunit (NCBI) compare
b3261 fis -1.6 -3.6 DNA-binding protein Fis (NCBI) compare
b1984 asnW -1.6 -1.5 tRNA-Asn (NCBI) compare
b2287 nuoB -1.6 -4.2 NADH dehydrogenase subunit B (NCBI) compare
b2286 nuoC -1.6 -5.3 NADH:ubiquinone oxidoreductase, chain C,D (RefSeq) compare
b3786 rffE -1.6 -13.2 UDP-N-acetyl glucosamine-2-epimerase (NCBI) compare
b1863 ruvC -1.6 -3.5 Holliday junction resolvase (NCBI) compare
b2808 gcvA -1.5 -5.8 DNA-binding transcriptional dual regulator (NCBI) compare
b3388 damX -1.5 -10.6 hypothetical protein (NCBI) compare
b4375 prfC -1.5 -4.9 peptide chain release factor 3 (NCBI) compare
b2278 nuoL -1.5 -9.4 NADH dehydrogenase subunit L (NCBI) compare
b2276 nuoN -1.5 -6.2 NADH:ubiquinone oxidoreductase, membrane subunit N (RefSeq) compare
b3784 rfe -1.5 -12.6 UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase (NCBI) compare
b1861 ruvA -1.5 -2.4 Holliday junction DNA helicase motor protein (NCBI) compare
b3794 rffM -1.5 -9.5 putative UDP-N-acetyl-D-mannosaminuronic acid transferase (NCBI) compare
b2284 nuoF -1.5 -5.8 NADH:ubiquinone oxidoreductase, chain F (NCBI) compare
b2277 nuoM -1.4 -6.6 NADH dehydrogenase subunit M (NCBI) compare
b1940 fliH -1.4 -5.9 flagellar biosynthesis; export of flagellar proteins? (VIMSS) compare
b3787 rffD -1.4 -11.6 UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase (NCBI) compare
b0721 sdhC -1.4 -4.7 succinate dehydrogenase cytochrome b556 large membrane subunit (NCBI) compare
b1693 aroD -1.4 -7.2 3-dehydroquinate dehydratase (NCBI) compare
b0888 trxB -1.4 -4.2 thioredoxin reductase, FAD/NAD(P)-binding (NCBI) compare
b0437 clpP -1.4 -7.6 ATP-dependent Clp protease proteolytic subunit (NCBI) compare
b3728 pstS -1.4 -3.5 phosphate transporter subunit (NCBI) compare
b0161 degP -1.4 -5.8 serine endoprotease (protease Do), membrane-associated (NCBI) compare
b1712 ihfA -1.4 -1.8 integration host factor subunit alpha (NCBI) compare
b0658 ybeX -1.4 -1.6 predicteed ion transport (NCBI) compare
b1290 sapF -1.4 -2.4 predicted antimicrobial peptide transporter subunit (NCBI) compare
b3390 aroK -1.4 -2.6 shikimate kinase I (NCBI) compare
b0726 sucA -1.3 -4.8 alpha-ketoglutarate decarboxylase (NCBI) compare
b2820 recB -1.3 -1.9 exonuclease V (RecBCD complex), beta subunit (NCBI) compare
b0722 sdhD -1.3 -4.4 succinate dehydrogenase cytochrome b556 small membrane subunit (NCBI) compare
b1291 sapD -1.3 -2.0 predicted antimicrobial peptide transporter subunit (NCBI) compare
b2175 spr -1.3 -4.9 predicted peptidase, outer membrane lipoprotein (NCBI) compare
b1175 minD -1.3 -6.7 membrane ATPase of the MinC-MinD-MinE system (NCBI) compare
b2501 ppk -1.3 -8.8 polyphosphate kinase (NCBI) compare
b0890 ftsK -1.3 -6.0 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b1892 flhD -1.3 -5.0 DNA-binding transcriptional dual regulator with FlhC (RefSeq) compare
b2516 yfgA -1.3 -6.8 hypothetical protein (NCBI) compare
b3839 tatC -1.3 -8.2 TatABCE protein translocation system subunit (NCBI) compare
b0724 sdhB -1.3 -5.6 succinate dehydrogenase, FeS subunit (NCBI) compare
b2620 smpB -1.3 -1.5 SsrA-binding protein (NCBI) compare
b3026 qseC -1.3 -5.7 sensory histidine kinase in two-component regulatory system with QseB (NCBI) compare
b3204 ptsN -1.3 -5.2 sugar-specific enzyme IIA component of PTS (NCBI) compare
b2897 ygfY -1.3 -5.1 hypothetical protein (NCBI) compare
b0101 yacG -1.2 -3.0 zinc-binding protein (NCBI) compare
b2846 yqeH -1.2 -1.0 orf, hypothetical protein (VIMSS) compare
b0630 lipB -1.2 -1.7 protein of lipoate biosynthesis (VIMSS) compare
b0222 lpcA -1.2 -3.3 phosphoheptose isomerase (NCBI) compare
b3162 deaD -1.2 -5.4 inducible ATP-independent RNA helicase (VIMSS) compare
b2285 nuoE -1.2 -2.9 NADH dehydrogenase subunit E (NCBI) compare
b1948 fliP -1.2 -5.6 flagellar biosynthesis protein P (NCBI) compare
b0723 sdhA -1.2 -8.5 succinate dehydrogenase flavoprotein subunit (NCBI) compare
b0677 nagA -1.2 -6.0 N-acetylglucosamine-6-phosphate deacetylase (NCBI) compare
b3706 trmE -1.2 -4.8 tRNA modification GTPase (NCBI) compare
b3741 gidA -1.2 -4.5 glucose-inhibited division protein A (NCBI) compare
b1938 fliF -1.2 -6.5 flagellar M-ring protein (NCBI) compare
b3281 aroE -1.2 -9.4 dehydroshikimate reductase, NAD(P)-binding (NCBI) compare
b3962 udhA -1.2 -7.0 putative oxidoreductase (VIMSS) compare
b1103 ycfF -1.2 -2.0 orf, hypothetical protein (VIMSS) compare
b2498 upp -1.1 -3.5 uracil phosphoribosyltransferase (VIMSS) compare
b0623 cspE -1.1 -2.0 cold shock protein E (NCBI) compare
b4239 treC -1.1 -1.8 trehalose-6-P hydrolase (NCBI) compare
b2330 yfcB -1.1 -1.9 putative adenine-specific methylase (VIMSS) compare
b2937 speB -1.1 -6.3 agmatinase (NCBI) compare
b0920 ycbC -1.1 -6.2 conserved inner membrane protein (NCBI) compare
b0676 nagC -1.1 -7.2 DNA-binding transcriptional dual regulator, repressor of N-acetylglucosamine (NCBI) compare
b3500 gor -1.1 -2.2 glutathione reductase (NCBI) compare
b2280 nuoJ -1.1 -4.6 NADH dehydrogenase subunit J (NCBI) compare
b1231 tyrT -1.1 -1.2 tRNA-Tyr (NCBI) compare
b1658 purR -1.1 -5.5 DNA-binding transcriptional repressor, hypoxanthine-binding (NCBI) compare
b2318 truA -1.1 -2.6 tRNA pseudouridine synthase A (NCBI) compare
b1945 fliM -1.1 -6.4 flagellar motor switch protein M (NCBI) compare
b1072 flgA -1.1 -5.8 flagellar basal body P-ring biosynthesis protein A (NCBI) compare
b1891 flhC -1.1 -4.1 DNA-binding transcriptional dual regulator with FlhD (NCBI) compare
b0729 sucD -1.1 -4.6 succinyl-CoA synthetase subunit alpha (NCBI) compare
b0902 pflA -1.1 -5.7 pyruvate formate lyase activating enzyme 1 (NCBI) compare
b3620 rfaF -1.1 -5.6 ADP-heptose:LPS heptosyltransferase II (NCBI) compare
b3462 ftsX -1.1 -6.0 predicted transporter subunit: membrane component of ABC superfamily (NCBI) compare
b1804 rnd -1.1 -4.5 ribonuclease D (NCBI) compare
b1079 flgH -1.1 -5.7 flagellar L-ring protein precursor H (NCBI) compare
b0685 ybfE -1.1 -4.1 orf, hypothetical protein (VIMSS) compare
b1889 motB -1.1 -3.5 flagellar motor protein MotB (NCBI) compare
b1077 flgF -1.0 -6.4 flagellar component of cell-proximal portion of basal-body rod (NCBI) compare
b1923 fliC -1.0 -6.3 flagellin (NCBI) compare
b1890 motA -1.0 -4.2 flagellar motor protein MotA (NCBI) compare
b3636 rpmG -1.0 -1.9 50S ribosomal protein L33 (NCBI) compare
b0843 ybjH -1.0 -1.9 hypothetical protein (NCBI) compare
b1977 asnT -1.0 -2.8 tRNA-Asn (NCBI) compare
b3806 cyaA -1.0 -4.9 adenylate cyclase (NCBI) compare
b1949 fliQ -1.0 -2.7 flagellar biosynthesis protein Q (NCBI) compare
b1176 minC -1.0 -3.4 septum formation inhibitor (NCBI) compare
b3821 pldA -1.0 -6.8 outer membrane phospholipase A (NCBI) compare
b1081 flgJ -1.0 -4.4 flagellar biosynthesis protein FlgJ (NCBI) compare
b3781 trxA -1.0 -4.2 thioredoxin 1 (VIMSS) compare
b0251 yafY -1.0 -1.7 CP4-6 prophage; predicted DNA-binding transcriptional regulator (RefSeq) compare
b2363 yfdT -1.0 -1.7 CPS-53 (KpLE1) prophage; predicted protein (NCBI) compare
b1075 flgD -1.0 -3.1 flagellar basal body rod modification protein D (NCBI) compare
b1476 fdnI -1.0 -0.8 formate dehydrogenase-N, cytochrome B556 (gamma) subunit, nitrate-inducible (NCBI) compare
b1083 flgL -1.0 -5.3 flagellar hook-associated protein L (NCBI) compare
b3961 oxyR -1.0 -6.7 DNA-binding transcriptional dual regulator (NCBI) compare
b0912 ihfB -1.0 -4.1 integration host factor subunit beta (NCBI) compare
b0728 sucC -1.0 -4.8 succinyl-CoA synthetase subunit beta (NCBI) compare
b3619 rfaD -1.0 -3.9 ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) compare
b4547 ypfN -1.0 -2.3 hypothetical protein (NCBI) compare
b0080 fruR -1.0 -5.5 DNA-binding transcriptional dual regulator (NCBI) compare
b1963 b1963 -1.0 -3.1 orf, hypothetical protein (VIMSS) compare
b1946 fliN -1.0 -2.5 flagellar motor switch protein (NCBI) compare
b2904 gcvH -1.0 -2.0 glycine cleavage system protein H (NCBI) compare
b0386 proC -1.0 -4.4 pyrroline-5-carboxylate reductase (NCBI) compare
b1925 fliS -1.0 -4.1 flagellar protein FliS (NCBI) compare
b1073 flgB -0.9 -3.6 flagellar basal-body rod protein B (NCBI) compare
b2894 xerD -0.9 -1.2 site-specific tyrosine recombinase XerD (NCBI) compare
b2188 yejM -0.9 -6.0 predicted hydrolase, inner membrane (NCBI) compare
b2218 rcsC -0.9 -7.1 hybrid sensory kinase in two-component regulatory system with RcsB and YojN (RefSeq) compare
b1536 ydeI -0.9 -1.3 hypothetical protein (NCBI) compare
b1888 cheA -0.9 -4.2 fused chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY: sensory histidine kinase/signal sensing protein (NCBI) compare
b1943 fliK -0.9 -5.3 flagellar hook-length control protein (NCBI) compare
b1556 b1556 -0.9 -2.6 orf, hypothetical protein (VIMSS) compare
b3863 polA -0.9 -1.2 DNA polymerase I (NCBI) compare
b0926 ycbK -0.9 -5.1 hypothetical protein (NCBI) compare
b1273 yciN -0.9 -1.3 hypothetical protein (NCBI) compare
b0840 deoR -0.9 -4.1 DNA-binding transcriptional repressor (NCBI) compare
b1082 flgK -0.9 -5.1 flagellar hook-associated protein K (NCBI) compare
b1506 yneL -0.9 -1.8 predicted transcriptional regulator (NCBI) compare
b1563 relE -0.9 -1.9 Qin prophage; toxin of the RelE-RelB toxin-antitoxin system (NCBI) compare
b2350 yfdG -0.9 -4.0 CPS-53 (KpLE1) prophage; bactoprenol-linked glucose translocase (flippase) (NCBI) compare
b4585 sroB -0.9 -1.2 Novel sRNA, function unknown (RefSeq) compare
b1884 cheR -0.9 -5.0 chemotaxis regulator, protein-glutamate methyltransferase (NCBI) compare
b3426 glpD -0.9 -3.4 sn-glycerol-3-phosphate dehydrogenase, aerobic, FAD/NAD(P)-binding (NCBI) compare
b1078 flgG -0.9 -5.8 flagellar component of cell-distal portion of basal-body rod (NCBI) compare
b1860 ruvB -0.9 -1.2 Holliday junction DNA helicase B (NCBI) compare
b2683 ygaH -0.9 -3.3 predicted inner membrane protein (NCBI) compare
b2822 recC -0.9 -4.0 exonuclease V (RecBCD complex), gamma chain (NCBI) compare
b1941 fliI -0.9 -5.1 flagellum-specific ATP synthase (NCBI) compare
b0720 gltA -0.9 -4.4 citrate synthase (NCBI) compare
b0928 aspC -0.9 -5.4 aspartate aminotransferase, PLP-dependent (NCBI) compare
b1924 fliD -0.9 -4.7 flagellar capping protein (NCBI) compare
b3838 tatB -0.9 -5.3 sec-independent translocase (NCBI) compare
b2569 lepA -0.9 -3.5 GTP-binding protein LepA (NCBI) compare
b1080 flgI -0.9 -5.3 homolog of Salmonella P-ring of flagella basal body (VIMSS) compare
b3621 rfaC -0.9 -4.1 ADP-heptose:LPS heptosyl transferase I (NCBI) compare
b1710 btuE -0.8 -1.9 predicted glutathione peroxidase (NCBI) compare
b1551 b1551 -0.8 -0.5 orf, hypothetical protein (VIMSS) compare
b2708 gutQ -0.8 -3.8 orf, hypothetical protein (VIMSS) compare
b2540 hcaC -0.8 -1.8 3-phenylpropionate dioxygenase, predicted ferredoxin subunit (NCBI) compare
b1635 gst -0.8 -2.4 glutathionine S-transferase (NCBI) compare
b3472 b3472 -0.8 -5.5 orf, hypothetical protein (VIMSS) compare
b4006 purH -0.8 -6.3 bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (NCBI) compare
b3933 ftsN -0.8 -6.0 essential cell division protein (NCBI) compare
b3164 pnp -0.8 -2.0 polynucleotide phosphorylase/polyadenylase (RefSeq) compare
b1434 ydcN -0.8 -1.7 predicted DNA-binding transcriptional regulator (NCBI) compare
b0049 apaH -0.8 -2.7 diadenosinetetraphosphatase (NCBI) compare
b0405 queA -0.8 -4.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase (NCBI) compare
b1881 cheZ -0.8 -2.4 chemotaxis regulator, protein phosphatase for CheY (NCBI) compare
b1594 dgsA -0.8 -3.0 DNA-binding transcriptional repressor (NCBI) compare
b1855 lpxM -0.8 -4.4 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase (NCBI) compare
b1482 osmC -0.8 -1.7 osmotically inducible, stress-inducible membrane protein (NCBI) compare
b2221 atoD -0.8 -2.4 acetyl-CoA:acetoacetyl-CoA transferase, alpha subunit (NCBI) compare
b3107 yhaL -0.8 -1.4 orf, hypothetical protein (VIMSS) compare


Specific Phenotypes

For 10 genes in this experiment