| | gene | name | fitness | t score | description | |
|---|
| b1192 | ldcA | -4.7 | -9.9 | L,D-carboxypeptidase A (NCBI) | compare |
| b1865 | nudB | -3.7 | -3.0 | dATP pyrophosphohydrolase (NCBI) | compare |
| b1261 | trpB | -3.4 | -3.5 | tryptophan synthase subunit beta (NCBI) | compare |
| b0149 | mrcB | -3.2 | -15.7 | penicillin-binding protein 1b (NCBI) | compare |
| b1260 | trpA | -3.1 | -6.2 | tryptophan synthase subunit alpha (NCBI) | compare |
| b2476 | purC | -3.1 | -4.0 | phosphoribosylaminoimidazole-succinocarboxamidesynthase (NCBI) | compare |
| b0523 | purE | -2.8 | -3.6 | phosphoribosylaminoimidazole carboxylase catalytic subunit (NCBI) | compare |
| b0145 | dksA | -2.8 | -5.7 | DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) | compare |
| b1850 | eda | -2.8 | -4.7 | keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (NCBI) | compare |
| b2830 | nudH | -2.7 | -2.6 | dinucleoside polyphosphate hydrolase (NCBI) | compare |
| b3870 | glnA | -2.6 | -5.5 | glutamine synthetase (NCBI) | compare |
| b2330 | yfcB | -2.5 | -2.8 | putative adenine-specific methylase (VIMSS) | compare |
| b2329 | aroC | -2.5 | -6.1 | chorismate synthase (NCBI) | compare |
| b2499 | purM | -2.4 | -5.0 | phosphoribosylaminoimidazole synthetase (NCBI) | compare |
| b4005 | purD | -2.4 | -11.0 | phosphoribosylamine--glycine ligase (NCBI) | compare |
| b1105 | ycfM | -2.3 | -7.1 | predicted outer membrane lipoprotein (NCBI) | compare |
| b3613 | yibP | -2.3 | -7.6 | putative membrane protein (VIMSS) | compare |
| b4006 | purH | -2.3 | -12.0 | bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (NCBI) | compare |
| b0522 | purK | -2.3 | -8.8 | phosphoribosylaminoimidazole carboxylase (NCBI) | compare |
| b1861 | ruvA | -2.3 | -2.6 | Holliday junction DNA helicase motor protein (NCBI) | compare |
| b0232 | yafN | -2.3 | -1.2 | predicted antitoxin of the YafO-YafN toxin-antitoxin system (NCBI) | compare |
| b0907 | serC | -2.2 | -5.8 | phosphoserine aminotransferase (NCBI) | compare |
| b2557 | purL | -2.2 | -11.7 | phosphoribosylformylglycinamidine synthase (NCBI) | compare |
| b0564 | appY | -2.1 | -1.0 | DLP12 prophage; DNA-binding transcriptional activator (NCBI) | compare |
| b3390 | aroK | -2.1 | -2.6 | shikimate kinase I (NCBI) | compare |
| b0088 | murD | -2.0 | -3.9 | UDP-N-acetylmuramoyl-L-alanyl-D-glutamatesynthetase (NCBI) | compare |
| b0004 | thrC | -2.0 | -7.0 | threonine synthase (NCBI) | compare |
| b2479 | gcvR | -1.9 | -6.2 | transcriptional regulation of gcv operon (VIMSS) | compare |
| b4214 | cysQ | -1.9 | -10.0 | PAPS (adenosine 3'-phosphate 5'-phosphosulfate) 3'(2'),5'-bisphosphate nucleotidase (NCBI) | compare |
| b3082 | ygjM | -1.9 | -3.6 | predicted DNA-binding transcriptional regulator (NCBI) | compare |
| b2312 | purF | -1.8 | -6.9 | amidophosphoribosyltransferase (NCBI) | compare |
| b4503 | yafF | -1.8 | -1.3 | no description | compare |
| b1550 | b1550 | -1.8 | -2.0 | orf, hypothetical protein (VIMSS) | compare |
| b0049 | apaH | -1.8 | -3.6 | diadenosinetetraphosphatase (NCBI) | compare |
| b2913 | serA | -1.7 | -6.6 | D-3-phosphoglycerate dehydrogenase (NCBI) | compare |
| b1860 | ruvB | -1.7 | -2.0 | Holliday junction DNA helicase B (NCBI) | compare |
| b3172 | argG | -1.7 | -10.0 | argininosuccinate synthase (NCBI) | compare |
| b2838 | lysA | -1.7 | -8.5 | diaminopimelate decarboxylase, PLP-binding (NCBI) | compare |
| b4655 | ythA | -1.7 | -1.5 | expressed protein (RefSeq) | compare |
| b2188 | yejM | -1.7 | -8.3 | predicted hydrolase, inner membrane (NCBI) | compare |
| b3021 | ygiT | -1.6 | -2.6 | predicted DNA-binding transcriptional regulator (NCBI) | compare |
| b1863 | ruvC | -1.6 | -3.2 | Holliday junction resolvase (NCBI) | compare |
| b4388 | serB | -1.6 | -5.8 | 3-phosphoserine phosphatase (NCBI) | compare |
| b0740 | tolB | -1.6 | -5.1 | translocation protein TolB precursor (NCBI) | compare |
| b3839 | tatC | -1.6 | -6.8 | TatABCE protein translocation system subunit (NCBI) | compare |
| b0033 | carB | -1.6 | -10.7 | carbamoyl-phosphate synthase large subunit (NCBI) | compare |
| b0003 | thrB | -1.6 | -6.9 | homoserine kinase (NCBI) | compare |
| b3940 | metL | -1.6 | -8.7 | bifunctional aspartate kinase II/homoserine dehydrogenase II (NCBI) | compare |
| b0889 | lrp | -1.6 | -3.4 | DNA-binding transcriptional dual regulator, leucine-binding (NCBI) | compare |
| b2531 | iscR | -1.5 | -1.8 | DNA-binding transcriptional repressor (NCBI) | compare |
| b1361 | ydaW | -1.5 | -0.7 | orf, hypothetical protein (VIMSS) | compare |
| b3389 | aroB | -1.5 | -8.7 | 3-dehydroquinate synthase (NCBI) | compare |
| b1663 | mdtK | -1.4 | -8.6 | multidrug efflux protein NorM (NCBI) | conserved |
| b3960 | argH | -1.4 | -7.9 | argininosuccinate lyase (NCBI) | compare |
| b1150 | ymfR | -1.4 | -1.4 | e14 prophage; predicted protein (NCBI) | compare |
| b2518 | ndk | -1.4 | -2.6 | nucleoside diphosphate kinase (NCBI) | compare |
| b2285 | nuoE | -1.4 | -2.6 | NADH dehydrogenase subunit E (NCBI) | compare |
| b0032 | carA | -1.3 | -4.0 | carbamoyl-phosphate synthase small subunit (NCBI) | compare |
| b3957 | argE | -1.2 | -8.5 | acetylornithine deacetylase (NCBI) | compare |
| b2699 | recA | -1.2 | -1.8 | recombinase A (NCBI) | compare |
| b0002 | thrA | -1.2 | -8.0 | bifunctional aspartokinase I/homeserine dehydrogenase I (NCBI) | compare |
| b3958 | argC | -1.2 | -8.4 | N-acetyl-gamma-glutamyl-phosphate reductase (NCBI) | compare |
| b3281 | aroE | -1.2 | -8.7 | dehydroshikimate reductase, NAD(P)-binding (NCBI) | compare |
| b4146 | yjeK | -1.2 | -2.4 | predicted lysine aminomutase (NCBI) | compare |
| b2750 | cysC | -1.2 | -6.2 | adenylylsulfate kinase (NCBI) | compare |
| b2818 | argA | -1.2 | -6.9 | N-acetylglutamate synthase (NCBI) | compare |
| b4436 | ryeC | -1.2 | -1.1 | Novel sRNA, function unknown; paralogous to the other QUAD sRNA genes unknown (RefSeq) | compare |
| b2414 | cysK | -1.2 | -5.7 | cysteine synthase A, O-acetylserine sulfhydrolase A subunit (NCBI) | compare |
| b2853 | ygeI | -1.2 | -0.7 | hypothetical protein (NCBI) | compare |
| b3204 | ptsN | -1.2 | -3.3 | sugar-specific enzyme IIA component of PTS (NCBI) | compare |
| b2313 | cvpA | -1.1 | -2.6 | membrane protein required for colicin V production (NCBI) | compare |
| b0741 | pal | -1.1 | -3.4 | peptidoglycan-associated outer membrane lipoprotein (NCBI) | compare |
| b1161 | ycgX | -1.1 | -0.9 | hypothetical protein (NCBI) | compare |
| b3623 | rfaK | -1.1 | -2.1 | lipopolysaccharide core biosynthesis (NCBI) | compare |
| b3941 | metF | -1.1 | -6.1 | 5,10-methylenetetrahydrofolate reductase (NCBI) | compare |
| b1830 | prc | -1.1 | -4.7 | carboxy-terminal protease for penicillin-binding protein 3 (NCBI) | compare |
| b2501 | ppk | -1.1 | -6.5 | polyphosphate kinase (NCBI) | compare |
| b2023 | hisH | -1.1 | -3.7 | imidazole glycerol phosphate synthase subunit HisH (NCBI) | compare |
| b3828 | metR | -1.1 | -6.4 | DNA-binding transcriptional activator, homocysteine-binding (NCBI) | compare |
| b2762 | cysH | -1.1 | -5.0 | phosphoadenosine phosphosulfate reductase (NCBI) | compare |
| b3959 | argB | -1.1 | -6.0 | acetylglutamate kinase (RefSeq) | compare |
| b0945 | pyrD | -1.1 | -7.1 | dihydroorotate dehydrogenase (NCBI) | compare |
| b0890 | ftsK | -1.1 | -4.6 | DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) | compare |
| b4239 | treC | -1.1 | -2.2 | trehalose-6-P hydrolase (NCBI) | compare |
| b0082 | mraW | -1.0 | -3.1 | S-adenosyl-methyltransferase (NCBI) | compare |
| b3860 | dsbA | -1.0 | -6.1 | periplasmic protein disulfide isomerase I (NCBI) | compare |
| b1185 | dsbB | -1.0 | -3.2 | reoxidizes DsbA protein following formation of disulfide bond in P-ring of flagella. (VIMSS) | compare |
| b2934 | cmtB | -1.0 | -1.1 | predicted mannitol-specific enzyme IIA component of PTS (NCBI) | compare |
| b1382 | ynbE | -1.0 | -1.7 | predicted lipoprotein (NCBI) | compare |
| b4042 | dgkA | -1.0 | -2.1 | diacylglycerol kinase (NCBI) | compare |
| b3741 | gidA | -1.0 | -4.4 | glucose-inhibited division protein A (NCBI) | compare |
| b1693 | aroD | -1.0 | -4.5 | 3-dehydroquinate dehydratase (NCBI) | compare |
| b0908 | aroA | -1.0 | -4.4 | 3-phosphoshikimate 1-carboxyvinyltransferase (NCBI) | compare |
| b3183 | obgE | -1.0 | -1.4 | GTPase involved in cell partioning and DNA repair (NCBI) | compare |
| b3386 | rpe | -1.0 | -0.6 | ribulose-phosphate 3-epimerase (NCBI) | compare |
| b0739 | tolA | -1.0 | -2.7 | cell envelope integrity inner membrane protein TolA (NCBI) | compare |
| b4202 | rpsR | -1.0 | -1.4 | 30S ribosomal protein S18 (NCBI) | compare |
| b1290 | sapF | -1.0 | -1.3 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b0888 | trxB | -1.0 | -2.7 | thioredoxin reductase, FAD/NAD(P)-binding (NCBI) | compare |
| b2221 | atoD | -0.9 | -3.5 | acetyl-CoA:acetoacetyl-CoA transferase, alpha subunit (NCBI) | compare |
| b1262 | trpC | -0.9 | -3.8 | N-(5-phosphoribosyl)anthranilate isomerase and indole-3-glycerolphosphate synthetase (VIMSS) | compare |
| b4481 | rffT | -0.9 | -4.6 | 4-alpha-L-fucosyltransferase (NCBI) | compare |
| b4435 | isrC | -0.9 | -1.9 | unknown RNA (NCBI) | compare |
| b2340 | sixA | -0.9 | -3.2 | phosphohistidine phosphatase (NCBI) | compare |
| b2912 | ygfA | -0.9 | -2.7 | putative ligase (VIMSS) | compare |
| b2620 | smpB | -0.9 | -0.9 | SsrA-binding protein (NCBI) | compare |
| b0617 | citD | -0.9 | -1.9 | citrate lyase, acyl carrier (gamma) subunit (NCBI) | compare |
| b1412 | azoR | -0.9 | -1.8 | acyl carrier protein phosphodiesterase (NCBI) | compare |
| b1742 | b1742 | -0.9 | -2.4 | orf, hypothetical protein (VIMSS) | compare |
| b3405 | ompR | -0.9 | -3.6 | osmolarity response regulator (NCBI) | compare |
| b2764 | cysJ | -0.9 | -5.3 | sulfite reductase, alpha subunit, flavoprotein (NCBI) | compare |
| b2839 | lysR | -0.9 | -4.6 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b3213 | gltD | -0.9 | -5.5 | glutamate synthase, 4Fe-4S protein, small subunit (NCBI) | compare |
| b3829 | metE | -0.9 | -6.5 | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (NCBI) | compare |
| b3290 | trkA | -0.9 | -1.6 | potassium transporter peripheral membrane component (NCBI) | compare |
| b1062 | pyrC | -0.9 | -5.0 | dihydroorotase (NCBI) | compare |
| b3794 | rffM | -0.8 | -4.4 | putative UDP-N-acetyl-D-mannosaminuronic acid transferase (NCBI) | compare |
| b3029 | ygiN | -0.8 | -1.5 | quinol monooxygenase (NCBI) | compare |
| b1175 | minD | -0.8 | -3.7 | membrane ATPase of the MinC-MinD-MinE system (NCBI) | compare |
| b2021 | hisC | -0.8 | -2.8 | histidinol-phosphate aminotransferase (NCBI) | compare |
| b2553 | glnB | -0.8 | -2.5 | regulatory protein P-II for glutamine synthetase (NCBI) | compare |
| b3838 | tatB | -0.8 | -4.1 | sec-independent translocase (NCBI) | compare |
| b1258 | yciF | -0.8 | -0.5 | hypothetical protein (NCBI) | compare |
| b3642 | pyrE | -0.8 | -2.8 | orotate phosphoribosyltransferase (NCBI) | compare |
| b4529 | ydbJ | -0.8 | -0.9 | hypothetical protein (NCBI) | compare |
| b3261 | fis | -0.8 | -2.1 | DNA-binding protein Fis (NCBI) | compare |
| b4155 | yjeA | -0.8 | -0.8 | putative lysyl-tRNA synthetase (VIMSS) | compare |
| b0920 | ycbC | -0.8 | -2.8 | conserved inner membrane protein (NCBI) | compare |
| b1286 | rnb | -0.8 | -1.7 | exoribonuclease II (NCBI) | compare |
| b1739 | osmE | -0.8 | -1.8 | DNA-binding transcriptional activator (NCBI) | compare |
| b1454 | yncG | -0.8 | -2.3 | predicted enzyme (NCBI) | compare |
| b3790 | rffC | -0.8 | -2.8 | TDP-fucosamine acetyltransferase (RefSeq) | compare |
| b3792 | wzxE | -0.8 | -4.3 | O-antigen translocase (NCBI) | compare |
| b1129 | phoQ | -0.8 | -1.4 | sensory histidine kinase in two-compoent regulatory system with PhoP (NCBI) | compare |
| b3205 | yhbJ | -0.8 | -2.0 | hypothetical protein (NCBI) | compare |
| b3203 | yhbH | -0.8 | -2.2 | predicted ribosome-associated, sigma 54 modulation protein (NCBI) | compare |
| b1936 | intG | -0.8 | -0.9 | predicted defective phage integrase (pseudogene) (RefSeq) | compare |
| b4215 | ytfI | -0.8 | -1.5 | hypothetical protein (NCBI) | compare |
| b3438 | gntR | -0.7 | -4.0 | DNA-binding transcriptional repressor (NCBI) | compare |
| b3706 | trmE | -0.7 | -3.0 | tRNA modification GTPase (NCBI) | compare |
| b3199 | yrbK | -0.7 | -1.6 | hypothetical protein (NCBI) | compare |
| b3238 | yhcN | -0.7 | -1.9 | orf, hypothetical protein (VIMSS) | compare |
| b0161 | degP | -0.7 | -3.8 | serine endoprotease (protease Do), membrane-associated (NCBI) | compare |
| b1656 | sodB | -0.7 | -1.9 | superoxide dismutase, Fe (NCBI) | compare |
| b3212 | gltB | -0.7 | -6.2 | glutamate synthase, large subunit (NCBI) | compare |
| b4414 | tff | -0.7 | -1.9 | unknown RNA (NCBI) | compare |
| b1505 | ydeT | -0.7 | -1.3 | hypothetical protein (RefSeq) | compare |
| b1814 | sdaA | -0.7 | -2.1 | L-serine deaminase I (NCBI) | compare |
| b0243 | proA | -0.7 | -4.2 | gamma-glutamyl phosphate reductase (NCBI) | compare |
| b0737 | tolQ | -0.7 | -1.8 | membrane spanning protein in TolA-TolQ-TolR complex (NCBI) | compare |
| b2019 | hisG | -0.7 | -2.6 | ATP phosphoribosyltransferase (NCBI) | compare |
| b3770 | ilvE | -0.7 | -4.7 | branched-chain amino acid aminotransferase (NCBI) | compare |
| b3787 | rffD | -0.7 | -4.8 | UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase (NCBI) | compare |
| b4532 | yncN | -0.7 | -1.9 | orf, hypothetical protein (VIMSS) | compare |
| b3784 | rfe | -0.7 | -5.1 | UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase (NCBI) | compare |
| b1179 | ycgL | -0.7 | -1.1 | conserved protein (NCBI) | compare |
| b0928 | aspC | -0.7 | -3.8 | aspartate aminotransferase, PLP-dependent (NCBI) | compare |
| b1063 | yceB | -0.7 | -2.1 | predicted lipoprotein (NCBI) | compare |
| b2504 | yfgG | -0.7 | -1.1 | Negative regulator of nickel and cobalt uptake (YfgG) (from data) | compare |
| b2263 | yfbB | -0.7 | -1.2 | predicted peptidase (NCBI) | compare |
| b0841 | ybjG | -0.7 | -2.4 | undecaprenyl pyrophosphate phosphatase (NCBI) | compare |
| b0222 | lpcA | -0.7 | -1.7 | phosphoheptose isomerase (NCBI) | compare |
| b3163 | nlpI | -0.7 | -2.7 | hypothetical protein (NCBI) | compare |
| b3388 | damX | -0.7 | -5.4 | hypothetical protein (NCBI) | compare |
| b0912 | ihfB | -0.7 | -2.0 | integration host factor subunit beta (NCBI) | compare |
| b3164 | pnp | -0.6 | -1.4 | polynucleotide phosphorylase/polyadenylase (RefSeq) | compare |
| b0386 | proC | -0.6 | -2.4 | pyrroline-5-carboxylate reductase (NCBI) | compare |
| b2824 | ygdB | -0.6 | -2.1 | orf, hypothetical protein (VIMSS) | compare |
| b0641 | rlpB | -0.6 | -1.5 | minor lipoprotein (NCBI) | compare |
| b2822 | recC | -0.6 | -2.2 | exonuclease V (RecBCD complex), gamma chain (NCBI) | compare |
| b3008 | metC | -0.6 | -4.5 | cystathionine beta-lyase (NCBI) | compare |
| b0696 | kdpC | -0.6 | -1.9 | potassium-transporting ATPase subunit C (NCBI) | compare |
| b4172 | hfq | -0.6 | -0.4 | RNA-binding protein Hfq (NCBI) | compare |
| b3811 | xerC | -0.6 | -1.4 | site-specific tyrosine recombinase XerC (NCBI) | compare |
| b1712 | ihfA | -0.6 | -1.0 | integration host factor subunit alpha (NCBI) | compare |
| b0929 | ompF | -0.6 | -3.4 | outer membrane porin 1a (Ia;b;F) (NCBI) | compare |
| b4647 | mokA | -0.6 | -0.6 | no description | compare |
| b2528 | iscA | -0.6 | -0.9 | iron-sulfur cluster assembly protein (NCBI) | compare |
| b0767 | ybhE | -0.6 | -2.4 | 6-phosphogluconolactonase (NCBI) | compare |
| b4418 | sraB | -0.6 | -1.5 | unknown RNA (NCBI) | compare |
| b4614 | sokA | -0.6 | -2.2 | no description | compare |
| b1293 | sapB | -0.6 | -0.7 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b0001 | thrL | -0.6 | -0.8 | thr operon leader peptide (NCBI) | compare |
| b2080 | b2080 | -0.6 | -1.2 | orf, hypothetical protein (VIMSS) | compare |
| b4313 | fimE | -0.6 | -3.8 | tyrosine recombinase/inversion of on/off regulator of fimA (NCBI) | compare |
| b1536 | ydeI | -0.6 | -0.8 | hypothetical protein (NCBI) | compare |
| b2894 | xerD | -0.6 | -0.7 | site-specific tyrosine recombinase XerD (NCBI) | compare |
| b3404 | envZ | -0.6 | -3.9 | osmolarity sensor protein (NCBI) | compare |
| b3868 | glnG | -0.6 | -2.0 | fused DNA-binding response regulator in two-component regulatory system with GlnL: response regulator/sigma54 interaction protein (NCBI) | compare |
| b3786 | rffE | -0.6 | -4.2 | UDP-N-acetyl glucosamine-2-epimerase (NCBI) | compare |
| b1919 | yedO | -0.6 | -1.7 | putative 1-aminocyclopropane-1-carboxylate deaminase (VIMSS) | compare |
| b1753 | ynjA | -0.6 | -1.7 | hypothetical protein (NCBI) | compare |
| b4101 | phnG | -0.6 | -2.1 | carbon-phosphorus lyase complex subunit (NCBI) | compare |
| b1778 | yeaA | -0.6 | -1.6 | methionine sulfoxide reductase B (NCBI) | compare |
| b1058 | yceO | -0.6 | -0.2 | hypothetical protein (NCBI) | compare |
| b1306 | pspC | -0.6 | -1.1 | DNA-binding transcriptional activator (NCBI) | compare |
| b1248 | b1248 | -0.6 | -0.7 | orf, hypothetical protein (VIMSS) | compare |
| b4505 | insX | -0.6 | -1.0 | predicted IS protein (RefSeq) | compare |
| b3398 | yrfF | -0.6 | -1.8 | predicted inner membrane protein (NCBI) | compare |
| b0437 | clpP | -0.5 | -2.5 | ATP-dependent Clp protease proteolytic subunit (NCBI) | compare |