Experiment set22IT008 for Escherichia coli BW25113

Compare to:

N4_phage 0.00009375 MOI TC1

200 most important genes:

  gene name fitness t score description  
b1882 cheY -2.9 -1.1 chemotaxis regulator transmitting signal to flagellar motor component (NCBI) compare
b1104 ycfL -2.8 -2.1 hypothetical protein (NCBI) compare
b4503 yafF -2.7 -1.4 no description compare
b2894 xerD -2.7 -1.8 site-specific tyrosine recombinase XerD (NCBI) compare
b1567 intK -2.6 -2.8 Qin prophage; predicted protein (RefSeq) compare
b1841 yobA -2.5 -2.3 hypothetical protein (NCBI) compare
b2259 pmrD -2.4 -1.5 polymyxin resistance protein B (VIMSS) compare
b0142 folK -2.4 -0.9 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase (NCBI) compare
b0730 mngR -2.4 -2.3 DNA-binding transcriptional dual regulator, fatty-acyl-binding (NCBI) compare
b2531 iscR -2.3 -2.4 DNA-binding transcriptional repressor (NCBI) compare
b1361 ydaW -2.2 -0.8 orf, hypothetical protein (VIMSS) compare
b1540 ydfH -2.0 -1.2 predicted DNA-binding transcriptional regulator (NCBI) compare
b1984 asnW -2.0 -1.5 tRNA-Asn (NCBI) compare
b0200 gmhB -2.0 -1.9 hypothetical protein (NCBI) compare
b3863 polA -2.0 -2.2 DNA polymerase I (NCBI) compare
b1613 manA -1.9 -2.4 mannose-6-phosphate isomerase (VIMSS) compare
b3290 trkA -1.9 -3.1 potassium transporter peripheral membrane component (NCBI) compare
b4048 yjbM -1.9 -1.3 hypothetical protein (NCBI) compare
b3183 obgE -1.8 -1.3 GTPase involved in cell partioning and DNA repair (NCBI) compare
b0630 lipB -1.8 -1.7 protein of lipoate biosynthesis (VIMSS) compare
b2934 cmtB -1.7 -1.2 predicted mannitol-specific enzyme IIA component of PTS (NCBI) compare
b1176 minC -1.7 -2.7 septum formation inhibitor (NCBI) compare
b2699 recA -1.7 -1.6 recombinase A (NCBI) compare
b0737 tolQ -1.7 -3.0 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b1709 btuD -1.7 -1.2 vitamin B12-transporter ATPase (NCBI) compare
b4375 prfC -1.6 -5.5 peptide chain release factor 3 (NCBI) compare
b1412 azoR -1.6 -1.8 acyl carrier protein phosphodiesterase (NCBI) compare
b3169 nusA -1.5 -2.2 transcription elongation factor NusA (NCBI) compare
b3162 deaD -1.5 -4.5 inducible ATP-independent RNA helicase (VIMSS) compare
b1454 yncG -1.5 -2.5 predicted enzyme (NCBI) compare
b1871 yecP -1.5 -3.8 predicted S-adenosyl-L-methionine-dependent methyltransferase (NCBI) compare
b3261 fis -1.5 -2.4 DNA-binding protein Fis (NCBI) compare
b4685 yrbN -1.5 -3.5 expressed protein (RefSeq) compare
b1383 ydbL -1.4 -3.1 orf, hypothetical protein (VIMSS) compare
b1961 dcm -1.4 -1.5 DNA cytosine methylase (NCBI) compare
b0247 ykfG -1.4 -1.5 CP4-6 prophage; predicted DNA repair protein (NCBI) compare
b1429 tehA -1.4 -1.0 potassium-tellurite ethidium and proflavin transporter (NCBI) compare
b4647 mokA -1.4 -0.9 no description compare
b2248 yfaX -1.3 -2.5 predicted DNA-binding transcriptional regulator (NCBI) compare
b1348 lar -1.3 -1.5 Rac prophage; restriction alleviation protein (NCBI) compare
b1563 relE -1.3 -1.7 Qin prophage; toxin of the RelE-RelB toxin-antitoxin system (NCBI) compare
b1758 b1758 -1.3 -1.0 putative cytochrome oxidase (VIMSS) compare
b3341 rpsG -1.2 -0.7 30S ribosomal protein S7 (NCBI) compare
b2330 yfcB -1.2 -1.5 putative adenine-specific methylase (VIMSS) compare
b1819 manZ -1.2 -3.1 mannose-specific enzyme IID component of PTS (NCBI) compare
b4203 rplI -1.2 -3.6 50S ribosomal protein L9 (NCBI) compare
b2642 yfjW -1.2 -1.1 CP4-57 prophage; predicted inner membrane protein (NCBI) compare
b1582 ynfA -1.2 -1.9 hypothetical protein (NCBI) compare
b2939 yqgB -1.2 -1.7 predicted protein (RefSeq) compare
b3181 greA -1.1 -4.9 transcription elongation factor: cleaves 3' nucleotide of paused mRNA (VIMSS) compare
b1108 ycfP -1.1 -1.2 orf, hypothetical protein (VIMSS) compare
b1236 galU -1.1 -3.3 glucose-1-phosphate uridylyltransferase (NCBI) compare
b1590 ynfH -1.1 -2.7 oxidoreductase, membrane subunit (NCBI) compare
b3728 pstS -1.1 -3.4 phosphate transporter subunit (NCBI) compare
b2822 recC -1.1 -4.6 exonuclease V (RecBCD complex), gamma chain (NCBI) compare
b1553 ydfP -1.1 -2.1 Qin prophage; conserved protein (NCBI) compare
b0114 aceE -1.1 -0.7 pyruvate dehydrogenase subunit E1 (NCBI) compare
b0145 dksA -1.1 -2.1 DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) compare
b0049 apaH -1.1 -2.4 diadenosinetetraphosphatase (NCBI) compare
b4544 yfbW -1.0 -3.2 hypothetical protein (NCBI) compare
b4603 rseX -1.0 -0.6 sRNA regulating ompA and ompC translation, with Hfq (RefSeq) compare
b1493 gadB -1.0 -0.6 glutamate decarboxylase B, PLP-dependent (NCBI) compare
b1196 ycgY -1.0 -2.2 hypothetical protein (NCBI) compare
b2930 yggF -1.0 -2.6 predicted hexoseP phosphatase (NCBI) compare
b0617 citD -1.0 -1.5 citrate lyase, acyl carrier (gamma) subunit (NCBI) compare
b0890 ftsK -1.0 -3.8 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b0641 rlpB -1.0 -2.2 minor lipoprotein (NCBI) compare
b4453 ldrD -1.0 -1.7 toxic polypeptide, small (NCBI) compare
b0741 pal -1.0 -2.8 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b1727 yniC -1.0 -2.2 predicted hydrolase (NCBI) compare
b2579 yfiD -1.0 -1.4 pyruvate formate lyase subunit (NCBI) compare
b2576 srmB -0.9 -2.3 ATP-dependent RNA helicase (NCBI) compare
b0222 lpcA -0.9 -1.3 phosphoheptose isomerase (NCBI) compare
b1516 lsrB -0.9 -2.9 AI2 transporter (NCBI) compare
b1129 phoQ -0.9 -0.6 sensory histidine kinase in two-compoent regulatory system with PhoP (NCBI) compare
b1860 ruvB -0.9 -0.6 Holliday junction DNA helicase B (NCBI) compare
b2288 nuoA -0.9 -1.7 NADH dehydrogenase I chain A (VIMSS) compare
b0051 ksgA -0.9 -2.3 dimethyladenosine transferase (NCBI) compare
b1850 eda -0.9 -1.4 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (NCBI) compare
b0439 lon -0.9 -3.4 DNA-binding ATP-dependent protease La (NCBI) compare
b4146 yjeK -0.9 -2.3 predicted lysine aminomutase (NCBI) compare
b1443 ydcV -0.9 -2.7 predicted spermidine/putrescine transporter subunit (NCBI) compare
b2356 yfdM -0.9 -1.5 orf, hypothetical protein (VIMSS) compare
b3613 yibP -0.9 -2.7 putative membrane protein (VIMSS) compare
b1677 lpp -0.9 -1.1 murein lipoprotein (NCBI) compare
b4538 yoeF -0.9 -1.1 hypothetical protein (RefSeq) compare
b1025 ycdT -0.9 -1.3 predicted diguanylate cyclase (NCBI) compare
b2830 nudH -0.9 -1.1 dinucleoside polyphosphate hydrolase (NCBI) compare
b1595 ynfL -0.9 -1.6 predicted DNA-binding transcriptional regulator (NCBI) compare
b2935 tktA -0.9 -1.6 transketolase 1, thiamin-binding (NCBI) compare
b4593 ymgI -0.9 -0.6 hypothetical protein (RefSeq) compare
b1765 ydjA -0.8 -0.5 predicted oxidoreductase (NCBI) compare
b0796 ybiH -0.8 -3.3 putative transcriptional regulator (VIMSS) compare
b3463 ftsE -0.8 -0.6 predicted transporter subunit: ATP-binding component of ABC superfamily (NCBI) compare
b1070 flgN -0.8 -0.8 export chaperone for FlgK and FlgL (NCBI) compare
b3500 gor -0.8 -1.2 glutathione reductase (NCBI) compare
b3811 xerC -0.8 -1.9 site-specific tyrosine recombinase XerC (NCBI) compare
b1290 sapF -0.8 -1.0 predicted antimicrobial peptide transporter subunit (NCBI) compare
b3101 yqjF -0.8 -2.4 orf, hypothetical protein (VIMSS) compare
b1675 ydhZ -0.8 -3.3 hypothetical protein (NCBI) compare
b1273 yciN -0.8 -1.0 hypothetical protein (NCBI) compare
b2281 nuoI -0.8 -1.3 NADH dehydrogenase subunit I (NCBI) compare
b1123 potD -0.8 -2.7 spermidine/putrescine ABC transporter periplasmic substrate-binding protein (NCBI) compare
b4458 oxyS -0.8 -1.1 global regulatory RNA (NCBI) compare
b2488 hyfH -0.8 -2.3 hydrogenase 4, Fe-S subunit (NCBI) compare
b1566 flxA -0.8 -1.4 Qin prophage; predicted protein (NCBI) compare
b1242 ychE -0.8 -1.7 predicted inner membrane protein (NCBI) compare
b1971 yedY -0.8 -2.5 hypothetical protein (NCBI) compare
b1610 tus -0.8 -3.0 DNA replication terminus site-binding protein (NCBI) compare
b2329 aroC -0.8 -3.1 chorismate synthase (NCBI) compare
b2820 recB -0.8 -1.0 exonuclease V (RecBCD complex), beta subunit (NCBI) compare
b0294 ykgK -0.8 -2.2 predicted regulator (NCBI) compare
b1936 intG -0.8 -0.7 predicted defective phage integrase (pseudogene) (RefSeq) compare
b2105 yohL -0.8 -1.9 hypothetical protein (NCBI) compare
b4631 ykgQ -0.8 -1.2 no description compare
b0828 iaaA -0.7 -2.1 L-asparaginase (NCBI) compare
b2362 yfdS -0.7 -2.3 CPS-53 (KpLE1) prophage; predicted protein (NCBI) compare
b2284 nuoF -0.7 -2.6 NADH:ubiquinone oxidoreductase, chain F (NCBI) compare
b1523 yneG -0.7 -0.6 hypothetical protein (NCBI) compare
b4649 ysaD -0.7 -2.8 no description compare
b1462 b1462 -0.7 -1.2 orf, hypothetical protein (VIMSS) compare
b1263 trpD -0.7 -1.9 bifunctional indole-3-glycerol-phosphate synthase/anthranilate phosphoribosyltransferase (NCBI) compare
b1120 cobB -0.7 -1.4 deacetylase of acs and cheY, regulates chemotaxis (NCBI) compare
b0946 ycbW -0.7 -2.5 orf, hypothetical protein (VIMSS) compare
b3512 GadE -0.7 -2.3 acid-responsive regulator of gadA and gadBC (Katherine Huang) compare
b2325 yfcL -0.7 -2.0 hypothetical protein (NCBI) compare
b3844 fre -0.7 -2.8 NAD(P)H-flavin reductase (NCBI) compare
b1185 dsbB -0.7 -1.1 reoxidizes DsbA protein following formation of disulfide bond in P-ring of flagella. (VIMSS) compare
b1949 fliQ -0.7 -1.5 flagellar biosynthesis protein Q (NCBI) compare
b2569 lepA -0.7 -2.5 GTP-binding protein LepA (NCBI) compare
b3426 glpD -0.7 -2.6 sn-glycerol-3-phosphate dehydrogenase, aerobic, FAD/NAD(P)-binding (NCBI) compare
b2518 ndk -0.7 -1.3 nucleoside diphosphate kinase (NCBI) compare
b4172 hfq -0.7 -0.6 RNA-binding protein Hfq (NCBI) compare
b1302 puuE -0.7 -2.0 GABA aminotransferase, PLP-dependent (NCBI) compare
b4413 sokC -0.7 -1.1 regulatory antisense RNA (NCBI) compare
b1359 ydaU -0.7 -1.4 Rac prophage; conserved protein (NCBI) compare
b4515 ybgT -0.7 -1.0 hypothetical protein (NCBI) compare
b3839 tatC -0.6 -3.4 TatABCE protein translocation system subunit (NCBI) compare
b1160 elbA -0.6 -0.4 hypothetical protein (NCBI) compare
b3999 yjaG -0.6 -3.9 hypothetical protein (NCBI) compare
b1282 yciH -0.6 -1.5 orf, hypothetical protein (VIMSS) compare
b4529 ydbJ -0.6 -0.6 hypothetical protein (NCBI) compare
b1060 yceP -0.6 -1.4 orf, hypothetical protein (VIMSS) compare
b3950 frwB -0.6 -1.2 predicted enzyme IIB component of PTS (NCBI) compare
b1130 phoP -0.6 -0.7 DNA-binding response regulator in two-component regulatory system with PhoQ (NCBI) compare
b2906 visC -0.6 -2.8 hypothetical protein (NCBI) compare
b2027 wzzB -0.6 -1.9 regulator of length of O-antigen component of lipopolysaccharide chains (VIMSS) compare
b1512 lsrR -0.6 -1.5 lsr operon transcriptional repressor (NCBI) compare
b4570 lomR -0.6 -0.8 no description compare
b0101 yacG -0.6 -0.9 zinc-binding protein (NCBI) compare
b1344 ydaO -0.6 -1.9 predicted C32 tRNA thiolase (NCBI) compare
b0610 rnk -0.6 -1.6 nucleoside diphosphate kinase regulator (NCBI) compare
b3164 pnp -0.6 -1.8 polynucleotide phosphorylase/polyadenylase (RefSeq) compare
b0454 ybaZ -0.6 -2.9 predicted methyltransferase (NCBI) compare
b1164 ycgZ -0.6 -0.6 hypothetical protein (NCBI) compare
b3002 yqhA -0.6 -1.0 hypothetical protein (NCBI) compare
b4435 isrC -0.6 -0.9 unknown RNA (NCBI) compare
b0424 thiJ -0.6 -2.1 4-methyl-5(beta-hydroxyethyl)-thiazole monophosphate synthesis (VIMSS) compare
b3623 rfaK -0.6 -1.6 lipopolysaccharide core biosynthesis (NCBI) compare
b1486 ddpB -0.6 -1.3 D-ala-D-ala transporter subunit (NCBI) compare
b1271 yciK -0.6 -1.7 short chain dehydrogenase (NCBI) compare
b4640 yoeG -0.6 -1.3 no description compare
b1074 flgC -0.6 -1.0 flagellar basal-body rod protein C (NCBI) compare
b1735 chbR -0.6 -1.5 DNA-binding transcriptional dual regulator (NCBI) compare
b1817 manX -0.6 -2.3 fused mannose-specific PTS enzymes: IIA component/IIB component (NCBI) compare
b2629 yfjM -0.6 -1.6 CP4-57 prophage; predicted protein (NCBI) compare
b0082 mraW -0.6 -1.4 S-adenosyl-methyltransferase (NCBI) compare
b1507 hipA -0.6 -1.4 regulator with hipB (NCBI) compare
b1764 selD -0.6 -2.2 selenophosphate synthetase (NCBI) compare
b1674 ydhY -0.6 -2.7 predicted 4Fe-4S ferridoxin-type protein (NCBI) compare
b1126 potA -0.6 -1.8 putrescine/spermidine ABC transporter ATPase protein (NCBI) compare
b2466 ypfG -0.6 -1.8 hypothetical protein (NCBI) compare
b1307 pspD -0.6 -0.8 peripheral inner membrane phage-shock protein (NCBI) compare
b2277 nuoM -0.6 -2.1 NADH dehydrogenase subunit M (NCBI) compare
b1660 ydhC -0.6 -1.4 predicted transporter (NCBI) compare
b3860 dsbA -0.6 -3.4 periplasmic protein disulfide isomerase I (NCBI) compare
b0720 gltA -0.6 -2.6 citrate synthase (NCBI) compare
b4060 yjcB -0.6 -2.7 orf, hypothetical protein (VIMSS) compare
b1513 lsrA -0.6 -1.8 fused AI2 transporter subunits of ABC superfamily: ATP-binding components (NCBI) compare
b3636 rpmG -0.6 -1.0 50S ribosomal protein L33 (NCBI) compare
b0437 clpP -0.6 -1.9 ATP-dependent Clp protease proteolytic subunit (NCBI) compare
b1838 pphA -0.6 -1.9 protein phosphatase 1 modulates phosphoproteins, signals protein misfolding (VIMSS) compare
b3443 yrhA -0.5 -0.9 orf, hypothetical protein (VIMSS) compare
b2449 yffR -0.5 -1.8 CPZ-55 prophage; predicted protein (NCBI) compare
b0059 hepA -0.5 -4.1 ATP-dependent helicase HepA (NCBI) compare
b2072 yegK -0.5 -2.1 hypothetical protein (NCBI) compare
b2809 b2809 -0.5 -1.5 orf, hypothetical protein (VIMSS) compare
b2807 ygdD -0.5 -1.6 conserved inner membrane protein (NCBI) compare
b1693 aroD -0.5 -1.7 3-dehydroquinate dehydratase (NCBI) compare
b3280 yrdB -0.5 -1.7 hypothetical protein (NCBI) compare
b0976 hyaE -0.5 -1.4 protein involved in processing of HyaA and HyaB proteins (NCBI) compare
b2326 yfcM -0.5 -2.5 hypothetical protein (NCBI) compare
b1848 yebG -0.5 -0.8 conserved protein regulated by LexA (NCBI) compare
b1814 sdaA -0.5 -1.7 L-serine deaminase I (NCBI) compare
b3229 sspA -0.5 -1.5 stringent starvation protein A (NCBI) compare
b3190 yrbA -0.5 -2.2 orf, hypothetical protein (VIMSS) compare
b4596 yciZ -0.5 -0.9 hypothetical protein (RefSeq) compare
b3032 cpdA -0.5 -2.3 cyclic 3',5'-adenosine monophosphate phosphodiesterase (NCBI) compare
b0189 yaeO -0.5 -1.7 orf, hypothetical protein (VIMSS) compare
b0401 brnQ -0.5 -2.6 predicted branched chain amino acid transporter (LIV-II) (NCBI) compare


Specific Phenotypes

For 3 genes in this experiment

For phage N4_phage in Escherichia coli BW25113

For phage N4_phage across organisms