Experiment set1S555 for Paraburkholderia sabiae LMG 24235

Compare to:

L-Histidine carbon source

200 most detrimental genes:

  gene name fitness t score description  
QEN71_RS28880 +3.2 18.0 flagellar assembly peptidoglycan hydrolase FlgJ compare
QEN71_RS29495 +3.0 7.8 HU family DNA-binding protein compare
QEN71_RS28885 +2.9 15.4 flagellar basal body P-ring protein FlgI compare
QEN71_RS28915 +2.9 17.6 flagellar basal body rod protein FlgC compare
QEN71_RS28905 +2.9 23.5 flagellar hook protein FlgE compare
QEN71_RS21240 +2.7 21.5 L,D-transpeptidase compare
QEN71_RS28895 +2.7 10.1 flagellar basal-body rod protein FlgG compare
QEN71_RS28955 +2.6 17.3 flagellar biosynthesis protein FlhA compare
QEN71_RS22025 +2.6 15.0 hypothetical protein compare
QEN71_RS28900 +2.6 8.5 flagellar basal-body rod protein FlgF compare
QEN71_RS28925 +2.5 14.0 flagellar basal body P-ring formation chaperone FlgA compare
QEN71_RS28960 +2.5 17.9 flagellar biosynthesis protein FlhB compare
QEN71_RS26950 +2.4 8.0 LPS assembly lipoprotein LptE compare
QEN71_RS28855 +2.3 20.0 flagellar biosynthetic protein FliR compare
QEN71_RS28920 +2.3 6.8 flagellar basal body rod protein FlgB compare
QEN71_RS04585 +2.3 17.9 MucB/RseB C-terminal domain-containing protein compare
QEN71_RS28940 +2.2 11.8 RNA polymerase sigma factor FliA compare
QEN71_RS15185 +2.1 19.5 RNA polymerase sigma factor RpoD compare
QEN71_RS15190 +2.0 10.3 hypothetical protein compare
QEN71_RS04725 +1.9 17.9 glycosyltransferase family 4 protein compare
QEN71_RS28815 +1.9 12.0 flagellar export protein FliJ compare
QEN71_RS25150 +1.9 8.6 ATPase compare
QEN71_RS28910 +1.9 7.1 flagellar hook assembly protein FlgD compare
QEN71_RS14360 +1.9 3.1 MxaS protein compare
QEN71_RS28805 +1.8 6.2 flagellar assembly protein FliH compare
QEN71_RS04720 +1.8 14.6 ABC transporter ATP-binding protein compare
QEN71_RS08930 +1.7 2.9 hypothetical protein compare
QEN71_RS05310 +1.7 12.8 MerR family transcriptional regulator compare
QEN71_RS02995 +1.7 4.1 cold shock domain-containing protein CspD compare
QEN71_RS23370 +1.7 5.2 arginine/ornithine succinyltransferase subunit alpha compare
QEN71_RS22425 +1.6 10.3 SMR family transporter compare
QEN71_RS28820 +1.6 6.3 flagellar hook-length control protein FliK compare
QEN71_RS05450 +1.6 5.6 outer membrane protein assembly factor BamC compare
QEN71_RS42215 +1.6 5.7 4Fe-4S dicluster domain-containing protein compare
QEN71_RS36660 +1.6 2.4 DeoR/GlpR family DNA-binding transcription regulator compare
QEN71_RS41360 +1.6 6.8 Lrp/AsnC family transcriptional regulator compare
QEN71_RS12460 +1.6 11.5 PAS domain-containing protein compare
QEN71_RS28810 +1.6 6.3 flagellar protein export ATPase FliI compare
QEN71_RS21800 +1.5 8.9 ankyrin repeat domain-containing protein compare
QEN71_RS17700 +1.5 10.0 HAMP domain-containing sensor histidine kinase compare
QEN71_RS28845 +1.5 11.1 flagellar type III secretion system pore protein FliP compare
QEN71_RS28890 +1.5 6.4 flagellar basal body L-ring protein FlgH compare
QEN71_RS28850 +1.5 8.1 flagellar biosynthesis protein FliQ compare
QEN71_RS00135 +1.5 11.5 LysR family transcriptional regulator compare
QEN71_RS28680 +1.5 12.4 TraB/GumN family protein compare
QEN71_RS03690 +1.5 8.2 porin compare
QEN71_RS15015 +1.5 2.9 glycosyltransferase family 9 protein compare
QEN71_RS06410 +1.4 12.0 [protein-PII] uridylyltransferase compare
QEN71_RS14760 +1.4 11.0 CDP-alcohol phosphatidyltransferase family protein compare
QEN71_RS35025 +1.4 10.5 efflux RND transporter permease subunit compare
QEN71_RS28840 +1.3 8.8 flagellar biosynthetic protein FliO compare
QEN71_RS01755 +1.3 11.3 RNA polymerase factor sigma-54 compare
QEN71_RS28950 +1.3 7.7 flagellar biosynthesis protein FlhF compare
QEN71_RS24455 +1.3 11.3 glycosyltransferase family 4 protein compare
QEN71_RS29035 +1.3 9.4 flagellar transcriptional regulator FlhD compare
QEN71_RS38070 +1.3 2.5 type III secretion system export apparatus subunit SctT compare
QEN71_RS16375 +1.3 9.6 NAD-dependent epimerase/dehydratase family protein compare
QEN71_RS14455 +1.3 8.5 phosphoenolpyruvate mutase compare
QEN71_RS05985 +1.3 4.2 tetratricopeptide repeat protein compare
QEN71_RS23295 +1.3 5.1 IclR family transcriptional regulator compare
QEN71_RS21815 +1.3 4.4 dTMP kinase compare
QEN71_RS00505 +1.2 9.3 response regulator transcription factor RqpR compare
QEN71_RS26925 +1.2 7.7 MurR/RpiR family transcriptional regulator compare
QEN71_RS39620 +1.2 2.4 proline/glycine betaine ABC transporter permease compare
QEN71_RS14450 +1.2 8.6 phosphonopyruvate decarboxylase compare
QEN71_RS27425 +1.2 8.1 penicillin-binding protein 2 compare
QEN71_RS14745 +1.2 7.1 phosphocholine cytidylyltransferase family protein compare
QEN71_RS21955 +1.2 8.4 SurA N-terminal domain-containing protein compare
QEN71_RS03650 +1.2 4.9 YicC/YloC family endoribonuclease compare
QEN71_RS06800 +1.2 2.0 transposase compare
QEN71_RS06615 +1.2 8.3 GntR family transcriptional regulator compare
QEN71_RS26430 +1.2 2.9 DedA family protein compare
QEN71_RS42240 +1.1 4.2 homocitrate synthase compare
QEN71_RS08645 +1.1 2.7 GTP cyclohydrolase II compare
QEN71_RS34350 +1.1 2.2 dipeptidase compare
QEN71_RS25070 +1.1 2.3 aspartate 1-decarboxylase compare
QEN71_RS10675 +1.1 2.5 prepilin peptidase compare
QEN71_RS35030 +1.1 7.5 efflux transporter outer membrane subunit compare
QEN71_RS37540 +1.1 3.1 AraC family transcriptional regulator compare
QEN71_RS30020 +1.0 2.5 TetR/AcrR family transcriptional regulator compare
QEN71_RS14445 +1.0 6.3 2-aminoethylphosphonate aminotransferase compare
QEN71_RS02530 +1.0 7.8 efflux transporter outer membrane subunit compare
QEN71_RS28065 +1.0 2.7 penicillin-binding protein 1A compare
QEN71_RS24720 +1.0 1.3 DUF4399 domain-containing protein compare
QEN71_RS28800 +1.0 6.9 flagellar motor switch protein FliG compare
QEN71_RS03135 +1.0 8.6 CDP-6-deoxy-delta-3,4-glucoseen reductase compare
QEN71_RS02525 +1.0 8.7 efflux RND transporter permease subunit compare
QEN71_RS42220 +1.0 4.9 FAD-dependent monooxygenase compare
QEN71_RS15595 +1.0 2.2 ABC transporter ATP-binding protein compare
QEN71_RS33345 +1.0 3.1 hypothetical protein compare
QEN71_RS24775 +1.0 9.1 alpha,alpha-trehalose-phosphate synthase (UDP-forming) compare
QEN71_RS36130 +1.0 2.2 MBL fold metallo-hydrolase compare
QEN71_RS30305 +1.0 1.7 hemerythrin domain-containing protein compare
QEN71_RS24750 +1.0 7.4 DNA (cytosine-5-)-methyltransferase compare
QEN71_RS27865 +1.0 8.3 histidinol dehydrogenase compare
QEN71_RS06415 +1.0 7.8 type I methionyl aminopeptidase compare
QEN71_RS28795 +1.0 9.3 flagellar basal-body MS-ring/collar protein FliF compare
QEN71_RS27235 +1.0 6.5 cytochrome c biogenesis protein CcsA compare
QEN71_RS21610 +1.0 4.3 ProQ/FinO family protein compare
QEN71_RS44355 +0.9 2.6 tyrosine-type recombinase/integrase compare
QEN71_RS07710 +0.9 1.7 hypothetical protein compare
QEN71_RS02520 +0.9 6.7 efflux RND transporter periplasmic adaptor subunit compare
QEN71_RS37590 +0.9 1.9 DUF4148 domain-containing protein compare
QEN71_RS42910 +0.9 1.6 IS66 family transposase compare
QEN71_RS34660 +0.9 1.7 sterol desaturase family protein compare
QEN71_RS44630 +0.9 1.7 transposase zinc-binding domain-containing protein compare
QEN71_RS34040 +0.9 2.0 ATP-grasp domain-containing protein compare
QEN71_RS10925 +0.9 1.2 helix-turn-helix domain-containing protein compare
QEN71_RS14780 +0.9 5.8 porin compare
QEN71_RS32065 +0.9 2.7 hypothetical protein compare
QEN71_RS03265 +0.9 6.7 transglycosylase SLT domain-containing protein compare
QEN71_RS07745 +0.9 5.2 histidine ammonia-lyase compare
QEN71_RS24450 +0.9 7.3 O-antigen ligase family protein compare
QEN71_RS01575 +0.9 6.6 bifunctional helix-turn-helix transcriptional regulator/GNAT family N-acetyltransferase compare
QEN71_RS00400 +0.8 1.6 hypothetical protein compare
QEN71_RS27260 +0.8 7.5 RNA pyrophosphohydrolase compare
QEN71_RS07750 +0.8 4.4 histidine utilization repressor compare
QEN71_RS09420 +0.8 2.5 hypothetical protein compare
QEN71_RS24030 +0.8 2.2 histidine phosphatase family protein compare
QEN71_RS44505 +0.8 2.0 IS21-like element helper ATPase IstB compare
QEN71_RS08420 +0.8 3.6 DUF3331 domain-containing protein compare
QEN71_RS02965 +0.8 3.4 DUF192 domain-containing protein compare
QEN71_RS16410 +0.8 5.8 MMPL family transporter compare
QEN71_RS23020 +0.8 1.2 hypothetical protein compare
QEN71_RS22035 +0.8 6.0 ATP-binding protein compare
QEN71_RS09230 +0.8 2.0 ATPase compare
QEN71_RS15245 +0.8 7.2 aromatic ring-hydroxylating dioxygenase subunit alpha compare
QEN71_RS41370 +0.8 4.5 diaminopropionate ammonia-lyase compare
QEN71_RS30025 +0.8 2.0 ester cyclase compare
QEN71_RS19915 +0.8 0.9 DUF2795 domain-containing protein compare
QEN71_RS26540 +0.8 6.7 bifunctional [glutamate--ammonia ligase]-adenylyl-L-tyrosine phosphorylase/[glutamate--ammonia-ligase] adenylyltransferase compare
QEN71_RS21970 +0.8 1.0 HU family DNA-binding protein compare
QEN71_RS01630 +0.8 5.6 acyloxyacyl hydrolase compare
QEN71_RS34110 +0.7 1.7 LysR substrate-binding domain-containing protein compare
QEN71_RS25325 +0.7 1.7 DUF2844 domain-containing protein compare
QEN71_RS12610 +0.7 2.8 ABC transporter permease compare
QEN71_RS35430 +0.7 1.6 nuclear transport factor 2 family protein compare
QEN71_RS04645 +0.7 2.4 CsbD family protein compare
QEN71_RS42230 +0.7 2.6 electron transfer flavoprotein subunit beta/FixA family protein compare
QEN71_RS29240 +0.7 6.6 trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase compare
QEN71_RS16255 +0.7 2.6 SRPBCC family protein compare
QEN71_RS08925 +0.7 2.5 hypothetical protein compare
QEN71_RS15300 +0.7 1.2 ABC transporter permease compare
QEN71_RS41265 +0.7 1.7 Xaa-Pro peptidase family protein compare
QEN71_RS03865 +0.7 4.3 3-ketoacyl-ACP reductase FabG2 compare
QEN71_RS02685 +0.7 4.2 Lrp/AsnC family transcriptional regulator compare
QEN71_RS11075 +0.7 1.1 hypothetical protein compare
QEN71_RS18705 +0.7 1.5 electron transfer flavoprotein subunit alpha/FixB family protein compare
QEN71_RS33300 +0.7 1.8 shikimate dehydrogenase compare
QEN71_RS36010 +0.7 2.1 MFS transporter compare
QEN71_RS03665 +0.7 1.7 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase compare
QEN71_RS28645 +0.7 5.8 winged helix DNA-binding protein compare
QEN71_RS10315 +0.7 1.8 hypothetical protein compare
QEN71_RS17430 +0.7 1.4 response regulator transcription factor compare
QEN71_RS02745 +0.7 5.1 tRNA epoxyqueuosine(34) reductase QueG compare
QEN71_RS05455 +0.7 1.5 hypothetical protein compare
QEN71_RS18810 +0.7 1.5 hypothetical protein compare
QEN71_RS05360 +0.7 1.7 helix-turn-helix transcriptional regulator compare
QEN71_RS16950 +0.7 2.6 VOC family protein compare
QEN71_RS32445 +0.7 1.1 DUF971 domain-containing protein compare
QEN71_RS09485 +0.7 5.0 GntR family transcriptional regulator compare
QEN71_RS21915 +0.7 3.3 peptidylprolyl isomerase compare
QEN71_RS38210 +0.7 2.0 flagellar hook protein FlgE compare
QEN71_RS37890 +0.7 1.4 ABC transporter permease compare
QEN71_RS34805 +0.7 2.6 hypothetical protein compare
QEN71_RS35020 +0.7 4.8 efflux RND transporter periplasmic adaptor subunit compare
QEN71_RS32965 +0.7 2.0 AI-2E family transporter compare
QEN71_RS14525 +0.7 1.3 peptidylprolyl isomerase compare
QEN71_RS24745 +0.7 1.0 hypothetical protein compare
QEN71_RS08115 +0.7 1.3 DUF2164 domain-containing protein compare
QEN71_RS03855 +0.7 3.2 beta-ketoacyl-[acyl-carrier-protein] synthase family protein compare
QEN71_RS41365 +0.7 1.8 M20 aminoacylase family protein compare
QEN71_RS19880 +0.7 2.2 LysR family transcriptional regulator compare
QEN71_RS06125 +0.7 1.9 tetratricopeptide repeat protein compare
QEN71_RS32435 +0.7 1.3 DUF1003 domain-containing protein compare
QEN71_RS38250 +0.7 0.7 helix-turn-helix transcriptional regulator compare
QEN71_RS40895 +0.7 1.8 hypothetical protein compare
QEN71_RS32720 +0.7 0.9 HisA/HisF-related TIM barrel protein compare
QEN71_RS04650 +0.7 2.3 hypothetical protein compare
QEN71_RS17135 +0.7 0.8 hypothetical protein compare
QEN71_RS00115 +0.7 1.7 PaaI family thioesterase compare
QEN71_RS10535 +0.6 0.8 hypothetical protein compare
QEN71_RS31085 +0.6 2.1 helix-turn-helix domain-containing protein compare
QEN71_RS16430 +0.6 5.5 squalene--hopene cyclase compare
QEN71_RS42225 +0.6 3.4 electron transfer flavoprotein subunit alpha/FixB family protein compare
QEN71_RS04250 +0.6 2.8 M48 family metallopeptidase compare
QEN71_RS43335 +0.6 0.8 hypothetical protein compare
QEN71_RS04860 +0.6 6.0 polyphosphate kinase 1 compare
QEN71_RS27330 +0.6 2.1 DNA gyrase inhibitor YacG compare
QEN71_RS43255 +0.6 1.5 branched-chain amino acid ABC transporter permease compare
QEN71_RS26450 +0.6 4.1 AI-2E family transporter compare
QEN71_RS01030 +0.6 2.1 Lrp/AsnC family transcriptional regulator compare
QEN71_RS30870 +0.6 1.1 hypothetical protein compare
QEN71_RS10565 +0.6 5.7 ATP-binding protein compare
QEN71_RS30565 +0.6 1.3 MarR family transcriptional regulator compare
QEN71_RS20120 +0.6 5.2 flagellar transcriptional regulator FlhC compare
QEN71_RS37310 +0.6 2.0 S49 family peptidase compare
QEN71_RS37660 +0.6 1.7 LysR family transcriptional regulator compare
QEN71_RS05695 +0.6 4.9 M3 family metallopeptidase compare
QEN71_RS37350 +0.6 2.0 hypothetical protein compare


Specific Phenotypes

For 9 genes in this experiment

For carbon source L-Histidine in Paraburkholderia sabiae LMG 24235

For carbon source L-Histidine across organisms