| Pathway | #Steps | #Present | #Specific |
|---|
| L-aspartate biosynthesis | 1 | 1 | 1 |
| 3-(4-hydroxyphenyl)pyruvate biosynthesis | 1 | 1 | 1 |
| L-alanine biosynthesis II | 1 | 1 | 1 |
| L-alanine degradation III | 1 | 1 | 1 |
| L-aspartate degradation I | 1 | 1 | 1 |
| acetate conversion to acetyl-CoA | 1 | 1 | 1 |
| acetate and ATP formation from acetyl-CoA III | 1 | 1 | 1 |
| ethanol degradation II | 3 | 3 | 2 |
| ethanol degradation IV | 3 | 3 | 2 |
| ethanol degradation III | 3 | 2 | 2 |
| superpathway of L-alanine biosynthesis | 4 | 4 | 2 |
| putrescine degradation V | 2 | 2 | 1 |
| L-glutamate degradation II | 2 | 2 | 1 |
| malate/L-aspartate shuttle pathway | 2 | 2 | 1 |
| ethylene glycol degradation | 2 | 2 | 1 |
| L-alanine biosynthesis I | 2 | 2 | 1 |
| putrescine degradation I | 2 | 1 | 1 |
| L-alanine degradation V (oxidative Stickland reaction) | 2 | 1 | 1 |
| L-tryptophan degradation IV (via indole-3-lactate) | 2 | 1 | 1 |
| atromentin biosynthesis | 2 | 1 | 1 |
| L-tyrosine degradation II | 2 | 1 | 1 |
| C4 photosynthetic carbon assimilation cycle, NAD-ME type | 11 | 7 | 4 |
| pentose phosphate pathway (oxidative branch) I | 3 | 3 | 1 |
| superpathway of acetate utilization and formation | 3 | 3 | 1 |
| L-tyrosine biosynthesis I | 3 | 3 | 1 |
| L-phenylalanine biosynthesis I | 3 | 3 | 1 |
| L-alanine degradation II (to D-lactate) | 3 | 3 | 1 |
| putrescine degradation IV | 3 | 2 | 1 |
| L-isoleucine biosynthesis V | 3 | 2 | 1 |
| L-asparagine degradation III (mammalian) | 3 | 2 | 1 |
| hypotaurine degradation | 3 | 2 | 1 |
| L-phenylalanine degradation II (anaerobic) | 3 | 2 | 1 |
| pyruvate fermentation to acetate and alanine | 3 | 1 | 1 |
| indole-3-acetate biosynthesis VI (bacteria) | 3 | 1 | 1 |
| (R)-cysteate degradation | 3 | 1 | 1 |
| histamine degradation | 3 | 1 | 1 |
| sulfolactate degradation III | 3 | 1 | 1 |
| L-tyrosine degradation IV (to 4-methylphenol) | 3 | 1 | 1 |
| anaerobic energy metabolism (invertebrates, cytosol) | 7 | 7 | 2 |
| C4 photosynthetic carbon assimilation cycle, PEPCK type | 14 | 8 | 4 |
| superpathway of NAD/NADP - NADH/NADPH interconversion (yeast) | 8 | 6 | 2 |
| phytol degradation | 4 | 3 | 1 |
| superpathway of L-aspartate and L-asparagine biosynthesis | 4 | 3 | 1 |
| chitin deacetylation | 4 | 2 | 1 |
| L-tryptophan degradation X (mammalian, via tryptamine) | 4 | 2 | 1 |
| L-phenylalanine degradation III | 4 | 2 | 1 |
| D-arabinose degradation II | 4 | 2 | 1 |
| L-tyrosine degradation III | 4 | 2 | 1 |
| fatty acid α-oxidation I (plants) | 4 | 2 | 1 |
| putrescine degradation III | 4 | 1 | 1 |
| L-tryptophan degradation VIII (to tryptophol) | 4 | 1 | 1 |
| L-tyrosine degradation I | 5 | 5 | 1 |
| 2-methylcitrate cycle I | 5 | 5 | 1 |
| trans-4-hydroxy-L-proline degradation I | 5 | 4 | 1 |
| cytosolic NADPH production (yeast) | 5 | 4 | 1 |
| mitochondrial NADPH production (yeast) | 5 | 3 | 1 |
| octane oxidation | 5 | 3 | 1 |
| sphingosine and sphingosine-1-phosphate metabolism | 10 | 4 | 2 |
| dopamine degradation | 5 | 2 | 1 |
| L-tyrosine degradation V (reductive Stickland reaction) | 5 | 2 | 1 |
| L-tryptophan degradation XIII (reductive Stickland reaction) | 5 | 2 | 1 |
| superpathway of plastoquinol biosynthesis | 5 | 2 | 1 |
| L-phenylalanine degradation VI (reductive Stickland reaction) | 5 | 2 | 1 |
| 4-hydroxybenzoate biosynthesis I (eukaryotes) | 5 | 1 | 1 |
| glyoxylate cycle | 6 | 6 | 1 |
| superpathway of L-threonine biosynthesis | 6 | 6 | 1 |
| TCA cycle VIII (Chlamydia) | 6 | 5 | 1 |
| 2-methylcitrate cycle II | 6 | 5 | 1 |
| β-alanine biosynthesis II | 6 | 4 | 1 |
| L-alanine degradation VI (reductive Stickland reaction) | 6 | 4 | 1 |
| L-isoleucine biosynthesis IV | 6 | 4 | 1 |
| 3-methyl-branched fatty acid α-oxidation | 6 | 3 | 1 |
| formaldehyde oxidation I | 6 | 3 | 1 |
| superpathway of sulfolactate degradation | 6 | 2 | 1 |
| superpathway of bitter acids biosynthesis | 18 | 3 | 3 |
| coenzyme M biosynthesis II | 6 | 1 | 1 |
| adlupulone and adhumulone biosynthesis | 6 | 1 | 1 |
| alkane oxidation | 6 | 1 | 1 |
| lupulone and humulone biosynthesis | 6 | 1 | 1 |
| colupulone and cohumulone biosynthesis | 6 | 1 | 1 |
| noradrenaline and adrenaline degradation | 13 | 4 | 2 |
| superpathway of glycol metabolism and degradation | 7 | 7 | 1 |
| L-lysine biosynthesis VI | 7 | 6 | 1 |
| serotonin degradation | 7 | 3 | 1 |
| ceramide degradation by α-oxidation | 7 | 2 | 1 |
| limonene degradation IV (anaerobic) | 7 | 1 | 1 |
| pentose phosphate pathway | 8 | 8 | 1 |
| superpathway of ornithine degradation | 8 | 5 | 1 |
| aromatic biogenic amine degradation (bacteria) | 8 | 4 | 1 |
| ceramide and sphingolipid recycling and degradation (yeast) | 16 | 4 | 2 |
| superpathway of anaerobic energy metabolism (invertebrates) | 17 | 13 | 2 |
| superpathway of aromatic amino acid biosynthesis | 18 | 18 | 2 |
| Entner-Doudoroff pathway I | 9 | 9 | 1 |
| L-lysine biosynthesis I | 9 | 9 | 1 |
| superpathway of L-lysine, L-threonine and L-methionine biosynthesis I | 18 | 17 | 2 |
| superpathway of L-methionine biosynthesis (transsulfuration) | 9 | 8 | 1 |
| L-lysine biosynthesis II | 9 | 6 | 1 |
| superpathway of L-alanine fermentation (Stickland reaction) | 9 | 6 | 1 |
| Entner-Doudoroff pathway II (non-phosphorylative) | 9 | 6 | 1 |
| reductive glycine pathway of autotrophic CO2 fixation | 9 | 5 | 1 |
| L-phenylalanine degradation IV (mammalian, via side chain) | 9 | 5 | 1 |
| cis-geranyl-CoA degradation | 9 | 2 | 1 |
| superpathway of L-tyrosine biosynthesis | 10 | 10 | 1 |
| superpathway of L-phenylalanine biosynthesis | 10 | 10 | 1 |
| superpathway of coenzyme A biosynthesis II (plants) | 10 | 8 | 1 |
| rosmarinic acid biosynthesis I | 10 | 3 | 1 |
| superpathway of L-arginine, putrescine, and 4-aminobutanoate degradation | 11 | 6 | 1 |
| (S)-reticuline biosynthesis I | 11 | 4 | 1 |
| superpathway of L-methionine biosynthesis (by sulfhydrylation) | 12 | 12 | 1 |
| superpathway of glyoxylate bypass and TCA | 12 | 10 | 1 |
| indole-3-acetate biosynthesis II | 12 | 6 | 1 |
| aspartate superpathway | 25 | 24 | 2 |
| superpathway of L-isoleucine biosynthesis I | 13 | 13 | 1 |
| superpathway of L-arginine and L-ornithine degradation | 13 | 8 | 1 |
| superpathway of glyoxylate cycle and fatty acid degradation | 14 | 11 | 1 |
| superpathway of rosmarinic acid biosynthesis | 14 | 4 | 1 |
| superpathway of L-lysine, L-threonine and L-methionine biosynthesis II | 15 | 13 | 1 |
| superpathway of glucose and xylose degradation | 17 | 17 | 1 |
| superpathway of glycolysis and the Entner-Doudoroff pathway | 17 | 15 | 1 |
| heterolactic fermentation | 18 | 16 | 1 |
| superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass | 26 | 22 | 1 |
| anaerobic aromatic compound degradation (Thauera aromatica) | 27 | 5 | 1 |
| Methanobacterium thermoautotrophicum biosynthetic metabolism | 56 | 23 | 2 |
| superpathway of chorismate metabolism | 59 | 42 | 2 |
| superpathway of pentose and pentitol degradation | 42 | 23 | 1 |