| | gene | name | fitness | t score | description | |
|---|
| HMPREF1181_RS03315 | | -8.1 | -7.5 | N-acetylornithine carbamoyltransferase | compare |
| HMPREF1181_RS06570 | | -8.1 | -7.9 | bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase type II | compare |
| HMPREF1181_RS00050 | | -8.1 | -12.3 | threonine synthase | compare |
| HMPREF1181_RS01245 | | -7.9 | -2.4 | type II 3-dehydroquinate dehydratase | compare |
| HMPREF1181_RS03450 | | -7.5 | -5.9 | N-acetyl-gamma-glutamyl-phosphate reductase | compare |
| HMPREF1181_RS06565 | | -7.3 | -4.3 | aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme | compare |
| HMPREF1181_RS06575 | | -7.3 | -3.7 | prephenate dehydrogenase | compare |
| HMPREF1181_RS02880 | | -7.2 | -4.6 | M20 family metallo-hydrolase | compare |
| HMPREF1181_RS03445 | | -7.1 | -9.2 | aspartate aminotransferase family protein | compare |
| HMPREF1181_RS13805 | | -6.9 | -1.8 | histone H1 | compare |
| HMPREF1181_RS15350 | | -6.8 | -6.6 | tryptophan synthase subunit alpha | compare |
| HMPREF1181_RS14990 | | -6.8 | -10.0 | aspartate carbamoyltransferase | compare |
| HMPREF1181_RS03410 | | -6.8 | -11.3 | argininosuccinate lyase | compare |
| HMPREF1181_RS03465 | | -6.6 | -7.3 | GNAT family N-acetyltransferase | compare |
| HMPREF1181_RS03460 | | -6.5 | -9.7 | argininosuccinate synthase | compare |
| HMPREF1181_RS06355 | | -6.5 | -6.3 | orotidine-5'-phosphate decarboxylase | compare |
| HMPREF1181_RS00060 | | -6.4 | -13.0 | bifunctional aspartate kinase/homoserine dehydrogenase I | compare |
| HMPREF1181_RS15485 | | -6.3 | -7.5 | anaerobic ribonucleoside triphosphate reductase | compare |
| HMPREF1181_RS03440 | | -6.2 | -8.1 | pyrroline-5-carboxylate reductase | compare |
| HMPREF1181_RS06190 | | -6.1 | -2.3 | tetratricopeptide repeat protein | compare |
| HMPREF1181_RS11050 | | -6.1 | -13.4 | diaminopimelate decarboxylase | compare |
| HMPREF1181_RS02540 | | -6.0 | -5.3 | acetylglutamate kinase | compare |
| HMPREF1181_RS04125 | | -6.0 | -12.0 | hypothetical protein | compare |
| HMPREF1181_RS03405 | | -6.0 | -3.9 | SRPBCC family protein | compare |
| HMPREF1181_RS05605 | | -6.0 | -23.9 | phosphoribosylformylglycinamidine synthase | compare |
| HMPREF1181_RS07435 | | -6.0 | -14.4 | IMP dehydrogenase | compare |
| HMPREF1181_RS04130 | | -5.9 | -31.1 | SLBB domain-containing protein | compare |
| HMPREF1181_RS16865 | | -5.9 | -5.8 | D-3-phosphoglycerate dehydrogenase | compare |
| HMPREF1181_RS04650 | | -5.9 | -7.6 | dihydroorotase | compare |
| HMPREF1181_RS15490 | | -5.8 | -3.1 | anaerobic ribonucleoside-triphosphate reductase activating protein | compare |
| HMPREF1181_RS02530 | | -5.8 | -2.2 | shikimate kinase | compare |
| HMPREF1181_RS14180 | | -5.7 | -4.9 | dihydroorotate dehydrogenase | compare |
| HMPREF1181_RS03325 | | -5.7 | -13.5 | glutamate 5-kinase | compare |
| HMPREF1181_RS00055 | | -5.7 | -8.7 | cofactor-independent phosphoglycerate mutase | compare |
| HMPREF1181_RS03320 | | -5.6 | -10.7 | glutamate-5-semialdehyde dehydrogenase | compare |
| HMPREF1181_RS03765 | | -5.6 | -14.1 | pyridoxal phosphate-dependent aminotransferase | compare |
| HMPREF1181_RS15320 | | -5.6 | -7.0 | tryptophan synthase subunit beta | compare |
| HMPREF1181_RS11070 | | -5.6 | -4.4 | imidazole glycerol phosphate synthase subunit HisF | compare |
| HMPREF1181_RS14125 | | -5.5 | -10.4 | 3-isopropylmalate dehydrogenase | compare |
| HMPREF1181_RS06560 | | -5.5 | -5.1 | prephenate dehydratase | compare |
| HMPREF1181_RS14145 | | -5.5 | -13.5 | 3-isopropylmalate dehydratase large subunit | compare |
| HMPREF1181_RS11065 | | -5.4 | -6.6 | bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE | compare |
| HMPREF1181_RS15345 | | -5.3 | -8.3 | phosphoribosylanthranilate isomerase | compare |
| HMPREF1181_RS08275 | | -5.3 | -7.8 | 6-phosphofructokinase | compare |
| HMPREF1181_RS14140 | | -5.2 | -3.2 | 3-isopropylmalate dehydratase small subunit | compare |
| HMPREF1181_RS14185 | | -5.2 | -9.3 | dihydroorotate dehydrogenase electron transfer subunit | compare |
| HMPREF1181_RS14150 | | -5.2 | -13.0 | 2-isopropylmalate synthase | compare |
| HMPREF1181_RS00165 | | -5.1 | -8.2 | bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase | compare |
| HMPREF1181_RS11075 | | -5.0 | -12.0 | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase | compare |
| HMPREF1181_RS06130 | | -5.0 | -7.5 | glutamine-hydrolyzing GMP synthase | compare |
| HMPREF1181_RS07450 | | -4.9 | -4.4 | ATP-dependent Clp endopeptidase proteolytic subunit ClpP | compare |
| HMPREF1181_RS06340 | | -4.8 | -4.2 | phosphoribosylformylglycinamidine cyclo-ligase | compare |
| HMPREF1181_RS06660 | | -4.8 | -2.4 | hypothetical protein | compare |
| HMPREF1181_RS12530 | | -4.8 | -10.9 | GDP-mannose 4,6-dehydratase | compare |
| HMPREF1181_RS15340 | | -4.8 | -3.8 | indole-3-glycerol phosphate synthase TrpC | compare |
| HMPREF1181_RS10835 | | -4.7 | -10.5 | tetratricopeptide repeat protein | compare |
| HMPREF1181_RS15530 | | -4.7 | -11.8 | pyridoxal phosphate-dependent aminotransferase | compare |
| HMPREF1181_RS14995 | | -4.7 | -6.9 | aspartate carbamoyltransferase regulatory subunit | compare |
| HMPREF1181_RS05875 | | -4.6 | -1.4 | 30S ribosomal protein S1 | compare |
| HMPREF1181_RS04275 | | -4.6 | -11.1 | tetratricopeptide repeat protein | compare |
| HMPREF1181_RS17835 | | -4.6 | -1.7 | hypothetical protein | compare |
| HMPREF1181_RS11305 | | -4.5 | -5.6 | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | compare |
| HMPREF1181_RS06320 | | -4.5 | -1.4 | shikimate dehydrogenase | compare |
| HMPREF1181_RS04800 | | -4.5 | -9.7 | CDP-alcohol phosphatidyltransferase family protein | compare |
| HMPREF1181_RS01135 | | -4.5 | -1.6 | tRNA-Arg | compare |
| HMPREF1181_RS15135 | | -4.4 | -15.2 | DUF3078 domain-containing protein | compare |
| HMPREF1181_RS01315 | | -4.4 | -14.2 | hypothetical protein | compare |
| HMPREF1181_RS04860 | | -4.4 | -10.7 | histidinol dehydrogenase | compare |
| HMPREF1181_RS05610 | | -4.4 | -6.7 | response regulator | compare |
| HMPREF1181_RS16410 | | -4.4 | -9.4 | ATP-dependent Clp protease ATP-binding subunit | compare |
| HMPREF1181_RS09265 | | -4.3 | -1.8 | 3-dehydroquinate synthase | compare |
| HMPREF1181_RS15330 | | -4.3 | -9.1 | aminodeoxychorismate/anthranilate synthase component II | compare |
| HMPREF1181_RS03400 | | -4.3 | -2.3 | orotate phosphoribosyltransferase | compare |
| HMPREF1181_RS06085 | | -4.3 | -4.4 | aspartate 1-decarboxylase | compare |
| HMPREF1181_RS13230 | | -4.3 | -14.3 | sodium ion-translocating decarboxylase subunit beta | compare |
| HMPREF1181_RS16950 | | -4.3 | -9.9 | RNA polymerase sigma factor | compare |
| HMPREF1181_RS06310 | | -4.3 | -2.6 | phosphoribosylaminoimidazolesuccinocarboxamide synthase | compare |
| HMPREF1181_RS15335 | | -4.2 | -5.9 | anthranilate phosphoribosyltransferase | compare |
| HMPREF1181_RS14085 | | -4.2 | -9.9 | adenylosuccinate synthase | compare |
| HMPREF1181_RS03250 | | -4.2 | -4.8 | RluA family pseudouridine synthase | compare |
| HMPREF1181_RS04815 | | -4.2 | -10.0 | inositol-3-phosphate synthase | compare |
| HMPREF1181_RS15095 | | -4.1 | -8.7 | UDP-glucose 4-epimerase GalE | compare |
| HMPREF1181_RS01305 | | -4.1 | -17.1 | N-acetylneuraminate synthase family protein | compare |
| HMPREF1181_RS05725 | | -4.1 | -9.4 | DUF4831 family protein | compare |
| HMPREF1181_RS04855 | | -4.1 | -14.1 | histidinol-phosphate transaminase | compare |
| HMPREF1181_RS13340 | | -4.1 | -14.9 | tetratricopeptide repeat protein | compare |
| HMPREF1181_RS02275 | | -4.0 | -1.4 | 4-hydroxy-tetrahydrodipicolinate reductase | compare |
| HMPREF1181_RS10195 | | -4.0 | -9.3 | SMI1/KNR4 family protein | compare |
| HMPREF1181_RS07880 | | -4.0 | -0.9 | DUF4290 domain-containing protein | compare |
| HMPREF1181_RS15325 | | -4.0 | -10.3 | anthranilate synthase component I family protein | compare |
| HMPREF1181_RS06865 | | -4.0 | -1.9 | branched-chain amino acid aminotransferase | compare |
| HMPREF1181_RS01140 | | -4.0 | -15.9 | 2-oxoacid:acceptor oxidoreductase subunit alpha | compare |
| HMPREF1181_RS01325 | | -4.0 | -13.5 | glycosyltransferase | compare |
| HMPREF1181_RS01580 | | -3.9 | -7.5 | phosphoribosylamine--glycine ligase | compare |
| HMPREF1181_RS09330 | | -3.9 | -1.5 | 3-phosphoshikimate 1-carboxyvinyltransferase | compare |
| HMPREF1181_RS01310 | | -3.9 | -8.0 | NTP transferase domain-containing protein | compare |
| HMPREF1181_RS04850 | | -3.9 | -8.0 | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | compare |
| HMPREF1181_RS00940 | | -3.9 | -0.8 | 5-(carboxyamino)imidazole ribonucleotide mutase | compare |
| HMPREF1181_RS01145 | | -3.9 | -8.2 | 2-oxoacid:ferredoxin oxidoreductase subunit beta | compare |
| HMPREF1181_RS07465 | | -3.8 | -6.3 | RNA-binding protein | compare |
| HMPREF1181_RS04810 | | -3.8 | -1.8 | phosphatidylglycerophosphatase A | compare |
| HMPREF1181_RS08330 | | -3.8 | -16.3 | biosynthetic-type acetolactate synthase large subunit | compare |
| HMPREF1181_RS05780 | | -3.8 | -3.7 | SurA N-terminal domain-containing protein | compare |
| HMPREF1181_RS12860 | | -3.7 | -5.6 | hypothetical protein | compare |
| HMPREF1181_RS08190 | | -3.7 | -4.8 | cardiolipin synthase | compare |
| HMPREF1181_RS08315 | | -3.7 | -11.3 | ketol-acid reductoisomerase | compare |
| HMPREF1181_RS06505 | | -3.7 | -1.4 | ribulose-phosphate 3-epimerase | compare |
| HMPREF1181_RS16385 | | -3.6 | -3.8 | tetratricopeptide repeat protein | compare |
| HMPREF1181_RS07510 | | -3.6 | -5.2 | DUF177 domain-containing protein | compare |
| HMPREF1181_RS04120 | | -3.6 | -7.6 | UpxY family transcription antiterminator | compare |
| HMPREF1181_RS00790 | | -3.6 | -6.1 | mannose-1-phosphate guanylyltransferase | compare |
| HMPREF1181_RS08050 | | -3.5 | -1.8 | hypothetical protein | compare |
| HMPREF1181_RS04380 | | -3.5 | -13.4 | glycosyltransferase family 2 protein | compare |
| HMPREF1181_RS12515 | | -3.5 | -12.1 | 6-phosphogluconolactonase | compare |
| HMPREF1181_RS08335 | | -3.5 | -19.9 | dihydroxy-acid dehydratase | compare |
| HMPREF1181_RS12535 | | -3.4 | -8.9 | GDP-L-fucose synthase | compare |
| HMPREF1181_RS06930 | | -3.4 | -2.4 | tRNA 2-thiouridine(34) synthase MnmA | compare |
| HMPREF1181_RS11080 | | -3.4 | -7.6 | imidazole glycerol phosphate synthase subunit HisH | compare |
| HMPREF1181_RS05890 | | -3.3 | -10.3 | glutamine synthetase III | compare |
| HMPREF1181_RS04365 | | -3.3 | -15.5 | Gfo/Idh/MocA family oxidoreductase | compare |
| HMPREF1181_RS01535 | | -3.3 | -2.0 | phosphatase PAP2 family protein | compare |
| HMPREF1181_RS07010 | | -3.3 | -7.9 | adenylosuccinate lyase | compare |
| HMPREF1181_RS00190 | | -3.3 | -2.3 | translocation/assembly module TamB domain-containing protein | compare |
| HMPREF1181_RS16790 | | -3.2 | -5.8 | helix-turn-helix domain-containing protein | compare |
| HMPREF1181_RS10535 | | -3.2 | -2.0 | cob(I)yrinic acid a,c-diamide adenosyltransferase | compare |
| HMPREF1181_RS01320 | | -3.2 | -17.1 | glycosyltransferase | compare |
| HMPREF1181_RS12010 | | -3.2 | -9.8 | Gfo/Idh/MocA family oxidoreductase | compare |
| HMPREF1181_RS08495 | | -3.1 | -5.2 | methylmalonyl-CoA mutase | compare |
| HMPREF1181_RS16430 | | -3.1 | -0.7 | tRNA-Asp | compare |
| HMPREF1181_RS00185 | | -3.1 | -1.7 | BamA/TamA family outer membrane protein | compare |
| HMPREF1181_RS04370 | | -3.1 | -11.4 | glycosyltransferase family 4 protein | compare |
| HMPREF1181_RS04350 | | -3.1 | -11.0 | glycosyltransferase | compare |
| HMPREF1181_RS03365 | | -3.1 | -3.0 | OmpH family outer membrane protein | compare |
| HMPREF1181_RS01780 | | -3.1 | -11.3 | acetyl-CoA hydrolase/transferase family protein | compare |
| HMPREF1181_RS11900 | | -3.0 | -7.0 | saccharopine dehydrogenase family protein | compare |
| HMPREF1181_RS05475 | | -3.0 | -5.0 | Rossmann-like and DUF2520 domain-containing protein | compare |
| HMPREF1181_RS04375 | | -3.0 | -10.3 | EpsG family protein | compare |
| HMPREF1181_RS09150 | | -3.0 | -4.2 | ribosome silencing factor | compare |
| HMPREF1181_RS04405 | | -3.0 | -8.4 | sugar transferase | compare |
| HMPREF1181_RS14610 | | -3.0 | -3.4 | DUF4296 domain-containing protein | compare |
| HMPREF1181_RS15010 | | -2.9 | -8.9 | serine hydroxymethyltransferase | compare |
| HMPREF1181_RS15240 | | -2.9 | -6.2 | PD-(D/E)XK nuclease family protein | compare |
| HMPREF1181_RS14135 | | -2.9 | -6.9 | 2-isopropylmalate synthase | compare |
| HMPREF1181_RS15460 | | -2.9 | -7.2 | Na+/H+ antiporter NhaC family protein | compare |
| HMPREF1181_RS07445 | | -2.9 | -6.7 | ATP-dependent Clp protease ATP-binding subunit ClpX | compare |
| HMPREF1181_RS01665 | | -2.9 | -5.9 | DUF4271 domain-containing protein | compare |
| HMPREF1181_RS05800 | | -2.9 | -7.3 | hypothetical protein | compare |
| HMPREF1181_RS04355 | | -2.9 | -10.9 | LicD family protein | compare |
| HMPREF1181_RS04400 | | -2.9 | -9.8 | polysaccharide biosynthesis protein | compare |
| HMPREF1181_RS07455 | | -2.8 | -7.3 | trigger factor | compare |
| HMPREF1181_RS08340 | | -2.8 | -3.8 | FKBP-type peptidyl-prolyl cis-trans isomerase | compare |
| HMPREF1181_RS05665 | | -2.8 | -6.6 | pyruvate:ferredoxin (flavodoxin) oxidoreductase | compare |
| HMPREF1181_RS15440 | | -2.8 | -1.4 | bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase | compare |
| HMPREF1181_RS14340 | | -2.7 | -4.8 | endopeptidase La | compare |
| HMPREF1181_RS15660 | | -2.7 | -2.3 | adenosylcobinamide-GDP ribazoletransferase | compare |
| HMPREF1181_RS08325 | | -2.7 | -6.4 | acetolactate synthase small subunit | compare |
| HMPREF1181_RS14835 | | -2.7 | -10.1 | phosphatidylinositol-4-phosphate 5-kinase | compare |
| HMPREF1181_RS00760 | | -2.7 | -2.2 | MobC family plasmid mobilization relaxosome protein | compare |
| HMPREF1181_RS00865 | | -2.7 | -5.5 | helix-turn-helix transcriptional regulator | compare |
| HMPREF1181_RS04865 | | -2.7 | -4.9 | ATP phosphoribosyltransferase | compare |
| HMPREF1181_RS15235 | | -2.7 | -2.4 | UvrD-helicase domain-containing protein | compare |
| HMPREF1181_RS16715 | | -2.6 | -5.6 | hypothetical protein | compare |
| HMPREF1181_RS01255 | | -2.6 | -7.6 | tetratricopeptide repeat protein | compare |
| HMPREF1181_RS14115 | | -2.6 | -11.0 | tetratricopeptide repeat protein | compare |
| HMPREF1181_RS10590 | | -2.6 | -2.3 | cobalamin biosynthesis protein CbiD | compare |
| HMPREF1181_RS14850 | | -2.5 | -4.4 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase | compare |
| HMPREF1181_RS14245 | | -2.5 | -4.0 | agmatine deiminase family protein | compare |
| HMPREF1181_RS01585 | | -2.5 | -9.0 | hypothetical protein | compare |
| HMPREF1181_RS05125 | | -2.5 | -2.0 | terminase | compare |
| HMPREF1181_RS01730 | | -2.5 | -6.0 | class I SAM-dependent methyltransferase | compare |
| HMPREF1181_RS02415 | | -2.5 | -7.4 | 6-phosphofructokinase | compare |
| HMPREF1181_RS07870 | | -2.5 | -6.3 | YicC family protein | compare |
| HMPREF1181_RS06545 | | -2.5 | -8.4 | single-stranded-DNA-specific exonuclease RecJ | compare |
| HMPREF1181_RS08795 | | -2.5 | -7.9 | hypothetical protein | compare |
| HMPREF1181_RS05805 | | -2.5 | -6.1 | type III pantothenate kinase | compare |
| HMPREF1181_RS10565 | | -2.4 | -7.4 | TonB-dependent receptor | compare |
| HMPREF1181_RS04535 | | -2.4 | -4.9 | transcriptional repressor | compare |
| HMPREF1181_RS16445 | | -2.4 | -5.6 | GNAT family N-acetyltransferase | compare |
| HMPREF1181_RS15650 | | -2.4 | -1.7 | bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase | compare |
| HMPREF1181_RS02535 | | -2.4 | -6.6 | biosynthetic arginine decarboxylase | compare |
| HMPREF1181_RS04415 | | -2.4 | -7.1 | UpxY family transcription antiterminator | compare |
| HMPREF1181_RS04395 | | -2.4 | -6.5 | hypothetical protein | compare |
| HMPREF1181_RS16455 | | -2.4 | -2.5 | recombination protein RecR | compare |
| HMPREF1181_RS11750 | | -2.4 | -3.6 | Smr/MutS family protein | compare |
| HMPREF1181_RS16500 | | -2.3 | -7.5 | carboxynorspermidine decarboxylase | compare |
| HMPREF1181_RS04550 | | -2.3 | -9.9 | hypothetical protein | compare |
| HMPREF1181_RS10385 | | -2.3 | -0.8 | hypothetical protein | compare |
| HMPREF1181_RS04135 | | -2.3 | -1.8 | tRNA-Thr | compare |
| HMPREF1181_RS15445 | | -2.3 | -2.7 | sugar kinase | compare |
| HMPREF1181_RS01550 | | -2.3 | -1.9 | ribonuclease R | compare |
| HMPREF1181_RS11055 | | -2.2 | -4.5 | aspartate kinase | compare |
| HMPREF1181_RS04360 | | -2.2 | -5.2 | SDR family NAD(P)-dependent oxidoreductase | compare |
| HMPREF1181_RS00875 | | -2.2 | -6.9 | CPBP family intramembrane metalloprotease | compare |
| HMPREF1181_RS10540 | | -2.2 | -3.3 | cobyrinate a,c-diamide synthase | compare |
| HMPREF1181_RS07040 | | -2.2 | -0.9 | hypothetical protein | compare |
| HMPREF1181_RS08595 | | -2.2 | -6.3 | aspartate--ammonia ligase | compare |
| HMPREF1181_RS10735 | | -2.2 | -7.4 | hypothetical protein | compare |
| HMPREF1181_RS14790 | | -2.2 | -12.2 | alpha amylase C-terminal domain-containing protein | compare |
| HMPREF1181_RS00265 | | -2.1 | -9.7 | 23S ribosomal RNA | compare |
| HMPREF1181_RS10720 | | -2.1 | -4.9 | nitronate monooxygenase | compare |