Experiment set1S451 for Variovorax sp. SCN45

Compare to:

M9 with calcium pantothenate 10 mg/mL and thiamine HCl 50 mg/mL

200 most important genes:

  gene name fitness t score description  
GFF5158 -6.3 -4.3 Trehalose-6-phosphate phosphatase (EC 3.1.3.12) compare
GFF372 -4.8 -7.4 PMID: 11481431 compare
GFF5076 -4.7 -14.0 hypothetical protein compare
GFF2627 -4.7 -3.2 Chorismate synthase (EC 4.2.3.5) compare
GFF6022 -4.6 -8.3 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) compare
GFF6876 -4.5 -10.0 Aminotransferase, DegT/DnrJ/EryC1/StrS family compare
GFF6878 -4.4 -12.3 hypothetical protein compare
GFF5896 -4.3 -6.6 Anthranilate synthase, aminase component (EC 4.1.3.27) compare
GFF3265 -4.1 -2.8 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
GFF4626 -4.0 -7.2 dTDP-Rha:A-D-GlcNAc-diphosphoryl polyprenol, A-3-L-rhamnosyl transferase WbbL compare
GFF5261 -4.0 -8.9 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) compare
GFF244 -3.9 -4.7 Cys regulon transcriptional activator CysB compare
GFF2515 -3.7 -3.6 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA compare
GFF408 -3.6 -2.5 Two-component system response regulator OmpR compare
GFF6512 -3.6 -2.5 4-hydroxy-2-oxoglutarate aldolase (EC 4.1.3.16) @ 2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14) compare
GFF6875 -3.6 -6.9 hypothetical protein compare
GFF4625 -3.5 -6.6 Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase (EC 2.7.8.33) compare
GFF5118 -3.5 -4.1 gluconolactonase family protein compare
GFF944 -3.4 -4.0 Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
GFF255 -3.4 -3.2 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase (EC 2.3.1.117) compare
GFF3838 -3.3 -17.8 Phosphoenolpyruvate carboxylase (EC 4.1.1.31) compare
GFF3089 -3.3 -3.1 Amidophosphoribosyltransferase (EC 2.4.2.14) compare
GFF5513 -3.2 -2.2 N5-carboxyaminoimidazole ribonucleotide synthase (EC 6.3.4.18) compare
GFF6182 -3.2 -4.4 Chorismate mutase I (EC 5.4.99.5) / Prephenate dehydratase (EC 4.2.1.51) compare
GFF6513 -3.2 -7.6 Phosphogluconate dehydratase (EC 4.2.1.12) compare
GFF2659 -3.2 -4.2 Electron transfer flavoprotein, alpha subunit compare
GFF3928 -3.1 -3.0 Histone acetyltransferase HPA2 and related acetyltransferases compare
GFF3888 -3.1 -6.6 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
GFF966 -3.1 -8.1 Probable two-component transmembrane sensor histidine kinase transcription regulator protein (EC 2.7.3.-) compare
GFF5666 -3.1 -4.2 Prevent host death protein, Phd antitoxin compare
GFF3889 -3.0 -2.9 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
GFF239 -3.0 -2.8 DNA polymerase III chi subunit (EC 2.7.7.7) compare
GFF5325 -3.0 -2.9 3-dehydroquinate synthase (EC 4.2.3.4) compare
GFF3651 -2.9 -2.8 PTS system, IIA component compare
GFF6042 -2.7 -4.8 Fatty acid desaturase (EC 1.14.19.1); Delta-9 fatty acid desaturase (EC 1.14.19.1) compare
GFF3890 -2.7 -5.1 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
GFF5246 -2.7 -13.0 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
GFF5512 -2.7 -3.1 N5-carboxyaminoimidazole ribonucleotide mutase (EC 5.4.99.18) compare
GFF1756 -2.5 -2.4 hypothetical protein compare
GFF2847 -2.5 -3.4 histone-like nucleoid-structuring protein H-NS compare
GFF5267 -2.5 -3.8 Glucose-6-phosphate isomerase (EC 5.3.1.9) compare
GFF339 -2.5 -4.8 Exodeoxyribonuclease I (EC 3.1.11.1) compare
GFF302 -2.5 -2.4 Phosphoribosylamine--glycine ligase (EC 6.3.4.13) compare
GFF5324 -2.4 -2.8 Shikimate kinase I (EC 2.7.1.71) compare
GFF1105 -2.4 -3.6 Helicase compare
GFF3600 -2.4 -2.3 Pantothenate kinase type III, CoaX-like (EC 2.7.1.33) compare
GFF4606 -2.4 -1.9 3-ketoacyl-CoA thiolase [fadN-fadA-fadE operon] (EC 2.3.1.16) compare
GFF3941 -2.4 -2.3 Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) compare
GFF7295 -2.3 -6.1 HPr kinase/phosphorylase compare
GFF967 -2.3 -14.8 Pyruvate dehydrogenase E1 component (EC 1.2.4.1) compare
GFF5523 -2.3 -1.5 Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23) compare
GFF2570 -2.3 -3.8 Rhodanese-related sulfurtransferase YibN compare
GFF5065 -2.2 -1.5 Orotate phosphoribosyltransferase (EC 2.4.2.10) compare
GFF1206 -2.2 -8.7 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
GFF1324 -2.2 -2.9 Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3) / Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3) compare
GFF5509 -2.1 -3.9 Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6) compare
GFF576 -2.1 -4.9 Tol biopolymer transport system, TolR protein compare
GFF3264 -2.1 -4.8 Methionine biosynthesis protein MetW compare
GFF4482 -2.0 -2.9 Transcriptional regulator MraZ compare
GFF1106 -2.0 -3.3 UvrD/REP helicase compare
GFF2804 -2.0 -4.0 Membrane protein compare
GFF6263 -2.0 -1.3 Uncharacterized protein Atu0170, clustered with phosphonate utilization compare
GFF409 -2.0 -5.8 Osmolarity sensory histidine kinase EnvZ compare
GFF946 -1.9 -3.7 Iron-sulfur cluster regulator IscR compare
GFF168 -1.9 -5.8 MCP methyltransferase, CheR-type compare
GFF4724 -1.8 -5.2 Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
GFF5307 -1.8 -4.6 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.241) compare
GFF5369 -1.8 -2.3 Large-conductance mechanosensitive channel compare
GFF968 -1.8 -3.3 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12) compare
GFF291 -1.8 -9.0 Tol-Pal system peptidoglycan-associated lipoprotein PAL compare
GFF3438 -1.8 -2.3 Amidohydrolase family protein compare
GFF1205 -1.7 -5.7 Oxidoreductase probably involved in sulfite reduction compare
GFF5605 -1.7 -4.7 D-xylose ABC transporter, ATP-binding protein XylG compare
GFF6168 -1.7 -1.8 Na(+) H(+) antiporter subunit G compare
GFF6986 -1.7 -1.3 hypothetical protein compare
GFF6990 -1.7 -1.7 hypothetical protein compare
GFF243 -1.6 -4.5 Sirohydrochlorin cobaltochelatase CbiX(small) (EC 4.99.1.3) compare
GFF5603 -1.6 -9.3 D-xylose ABC transporter, substrate-binding protein XylF compare
GFF4352 -1.6 -1.7 Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) compare
GFF2688 -1.6 -2.0 Glutamine ABC transporter, substrate-binding protein GlnH compare
GFF5627 -1.6 -6.3 [4Fe-4S] cluster assembly scaffold protein Mrp (=ApbC) compare
GFF2128 -1.5 -8.2 Enoyl-CoA hydratase (EC 4.2.1.17) compare
GFF7380 -1.5 -7.5 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) compare
GFF4346 -1.5 -1.9 no description compare
GFF6250 -1.5 -7.8 Glutamate--cysteine ligase-like protein YbdK compare
GFF5317 -1.5 -1.7 Frataxin homolog CyaY, facilitates Fe-S cluster assembly, interacts with IscS compare
GFF3034 -1.5 -1.6 no description compare
GFF270 -1.4 -10.8 2-methylcitrate dehydratase (2-methyl-trans-aconitate forming) (EC 4.2.1.117) compare
GFF6465 -1.4 -2.5 hypothetical protein compare
GFF2575 -1.4 -9.3 Quinolinate synthetase (EC 2.5.1.72) compare
GFF2574 -1.4 -7.6 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
GFF4447 -1.4 -6.7 2-keto-3-deoxy-D-arabino-heptulosonate-7-phosphat e synthase I alpha (EC 2.5.1.54) compare
GFF2730 -1.4 -3.1 DNA topoisomerase IV subunit A (EC 5.99.1.3) compare
GFF5057 -1.4 -11.3 Peptidoglycan D,D-transpeptidase MrdA (EC 3.4.16.4) compare
GFF6334 -1.4 -1.9 no description compare
GFF7242 -1.4 -1.8 hypothetical protein compare
GFF6249 -1.4 -6.7 Transporter, monovalent cation:proton antiporter-2 (CPA2) family compare
GFF292 -1.4 -10.7 Tol-Pal system beta propeller repeat protein TolB compare
GFF575 -1.3 -6.8 Tol-Pal system protein TolQ compare
GFF5604 -1.3 -7.9 D-xylose ABC transporter, permease protein XylH compare
GFF4106 -1.3 -1.8 ABC transporter, ATP-binding protein (cluster 3, basic aa/glutamine/opines) compare
GFF15 -1.2 -1.2 no description compare
GFF6591 -1.2 -5.1 Transcriptional regulator, GntR family compare
GFF269 -1.2 -5.0 2-methylaconitate isomerase compare
GFF2637 -1.2 -1.6 no description compare
GFF6121 -1.2 -1.9 FIG003461: hypothetical protein compare
GFF5156 -1.2 -10.3 Alpha,alpha-trehalose-phosphate synthase [UDP-forming] (EC 2.4.1.15) compare
GFF4285 -1.2 -1.4 Tricarboxylate transport protein TctC compare
GFF6862 -1.2 -5.5 Two-component system sensor histidine kinase compare
GFF2300 -1.2 -7.6 Cytochrome oxidase biogenesis protein Cox11-CtaG, copper delivery to Cox1 compare
GFF6290 -1.2 -10.1 RNA polymerase sigma-54 factor RpoN compare
GFF4282 -1.2 -2.9 BUG/TctC family periplasmic protein compare
GFF2304 -1.2 -7.3 Cytochrome oxidase biogenesis protein Surf1, facilitates heme A insertion compare
GFF5927 -1.2 -2.3 3-oxoacyl-[ACP] synthase compare
GFF6700 -1.2 -2.7 Single-stranded-DNA-specific exonuclease RecJ compare
GFF5266 -1.2 -7.0 Transaldolase (EC 2.2.1.2) compare
GFF5414 -1.1 -7.3 hypothetical protein compare
GFF2090 -1.1 -2.9 Holliday junction ATP-dependent DNA helicase RuvB (EC 3.6.4.12) compare
GFF2073 -1.1 -3.9 Holliday junction ATP-dependent DNA helicase RuvA (EC 3.6.4.12) compare
GFF5323 -1.1 -8.3 Type IV pilus biogenesis protein PilQ compare
GFF7221 -1.1 -2.7 Protein lysine acetyltransferase Pat (EC 2.3.1.-) compare
GFF4748 -1.1 -1.8 Triosephosphate isomerase (EC 5.3.1.1) compare
GFF5030 -1.1 -1.3 no description compare
GFF2306 -1.1 -6.3 Heme A synthase, cytochrome oxidase biogenesis protein Cox15-CtaA compare
GFF2273 -1.1 -3.2 Transcriptional regulator, AcrR family compare
GFF4530 -1.1 -6.1 MBL-fold metallo-hydrolase superfamily compare
GFF2298 -1.1 -9.2 Cytochrome c oxidase polypeptide I (EC 1.9.3.1) compare
GFF6429 -1.1 -1.0 Pyruvate:Oxaloacetate transcarboxylase domain protein compare
GFF2297 -1.1 -8.0 Cytochrome c oxidase polypeptide II (EC 1.9.3.1) compare
GFF5319 -1.1 -9.0 Type IV pilus biogenesis protein PilM compare
GFF5322 -1.1 -6.1 Type IV pilus biogenesis protein PilP compare
GFF3050 -1.1 -1.9 Lactam utilization protein LamB compare
GFF1475 -1.1 -1.4 no description compare
GFF305 -1.1 -6.5 uncharacterized domain / RidA/YER057c/UK114 superfamily, group 5 compare
GFF273 -1.1 -5.4 Transcriptional regulator, Xre family compare
GFF6695 -1.1 -6.8 Ubiquinol-cytochrome C reductase, cytochrome B subunit (EC 1.10.2.2) compare
GFF3826 -1.1 -6.2 Response regulator receiver:LytTr DNA-binding region compare
GFF487 -1.1 -6.1 ATP-dependent protease La (EC 3.4.21.53) Type I compare
GFF2510 -1.0 -8.3 Type IV fimbrial assembly, ATPase PilB compare
GFF2573 -1.0 -5.8 Glycerol-3-phosphate dehydrogenase [NAD(P)+] (EC 1.1.1.94) compare
GFF5417 -1.0 -7.8 hypothetical protein compare
GFF821 -1.0 -1.9 Acetoacetyl-CoA reductase (EC 1.1.1.36) compare
GFF993 -1.0 -7.9 Type IV pilus biogenesis protein PilF compare
GFF3952 -1.0 -2.6 LSU ribosomal protein L19p compare
GFF5289 -1.0 -1.7 hypothetical protein compare
GFF1013 -1.0 -1.2 hypothetical protein compare
GFF2978 -1.0 -2.5 Aromatic ring-cleaving dioxygenase compare
GFF5412 -1.0 -5.0 no description compare
GFF5907 -1.0 -2.5 Biotin synthase-related enzyme compare
GFF577 -1.0 -1.3 TolA protein compare
GFF4432 -1.0 -7.2 Two-component system response regulator protein compare
GFF5490 -1.0 -8.2 Uncharacterized protein with LysM domain, COG1652 compare
GFF1984 -1.0 -2.3 Phospholipid and glycerol acyltransferase (EC 2.3.1.51) compare
GFF1202 -1.0 -5.4 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) compare
GFF6354 -1.0 -2.1 T6SS component TssK (ImpJ/VasE) compare
GFF2236 -1.0 -1.1 hypothetical protein compare
GFF33 -1.0 -7.1 Type IV pilus biogenesis protein PilZ compare
GFF3723 -1.0 -6.0 Cytochrome c5 compare
GFF6696 -1.0 -5.7 Ubiquinol-cytochrome C reductase, cytochrome C1 subunit compare
GFF2508 -1.0 -7.4 Leader peptidase (Prepilin peptidase) (EC 3.4.23.43) / N-methyltransferase (EC 2.1.1.-) compare
GFF6036 -1.0 -4.4 DNA translocase FtsK compare
GFF5049 -1.0 -0.8 NAD-dependent protein deacetylase of SIR2 family compare
GFF290 -1.0 -5.1 Cell division coordinator CpoB compare
GFF5310 -1.0 -6.4 Cytochrome c4 compare
GFF4668 -1.0 -1.9 hypothetical protein compare
GFF7178 -1.0 -1.7 Glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) compare
GFF3068 -1.0 -4.7 FIG00538108: hypothetical protein compare
GFF2302 -0.9 -6.2 Cytochrome c oxidase polypeptide III (EC 1.9.3.1) compare
GFF1535 -0.9 -1.5 Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) compare
GFF2699 -0.9 -1.4 4Fe-4S ferredoxin, iron-sulfur binding compare
GFF6087 -0.9 -5.0 Transcriptional regulator, AcrR family compare
GFF5813 -0.9 -1.7 Heavy metal sensor histidine kinase compare
GFF3254 -0.9 -7.0 Phosphotransferase involved in threonylcarbamoyladenosine t(6)A37 formation in tRNA compare
GFF6015 -0.9 -1.9 Transcriptional regulator PA0877, LysR family compare
GFF5416 -0.9 -6.8 Type IV fimbrial biogenesis protein PilW compare
GFF7195 -0.9 -1.3 Oligopeptide transport system permease protein OppB (TC 3.A.1.5.1) compare
GFF5418 -0.9 -8.5 Type IV fimbrial biogenesis protein PilY1 compare
GFF5321 -0.9 -6.5 Type IV pilus biogenesis protein PilO compare
GFF4319 -0.9 -1.9 Oxidoreductase, short-chain dehydrogenase/reductase family compare
GFF2027 -0.9 -5.6 2-hydroxychromene-2-carboxylate isomerase family protein compare
GFF268 -0.9 -4.4 Carboxyvinyl-carboxyphosphonate phosphorylmutase (EC 2.7.8.23) compare
GFF6246 -0.9 -3.1 Ribulose-phosphate 3-epimerase (EC 5.1.3.1) compare
GFF4216 -0.9 -1.0 ABC transporter, permease protein (cluster 3, basic aa/glutamine/opines) compare
GFF3715 -0.9 -2.1 Probable malonic semialdehyde reductase RutE (EC 1.1.1.298) compare
GFF2151 -0.9 -4.6 twitching motility protein PilG compare
GFF1573 -0.9 -1.1 Oxidoreductase, short-chain dehydrogenase/reductase family compare
GFF2781 -0.9 -2.1 Phosphopantetheine-binding compare
GFF2509 -0.9 -7.4 Type IV fimbrial assembly protein PilC compare
GFF5415 -0.9 -4.7 Type IV fimbrial biogenesis protein PilV compare
GFF5601 -0.9 -2.3 Predicted hydrolase of the alpha/beta-hydrolase fold compare
GFF7063 -0.9 -1.2 Antibiotic biosynthesis monooxygenase compare
GFF226 -0.8 -5.7 ABC transporter, ATP-binding protein (cluster 5, nickel/peptides/opines) / ABC transporter, ATP-binding protein (cluster 5, nickel/peptides/opines) compare
GFF1529 -0.8 -1.2 Transcriptional regulator, AcrR family compare
GFF6570 -0.8 -1.2 hypothetical protein compare
GFF1649 -0.8 -1.5 hypothetical protein compare
GFF6094 -0.8 -2.1 1,2-phenylacetyl-CoA epoxidase, subunit B (EC 1.14.13.149) compare
GFF2164 -0.8 -4.3 Transcriptional regulator, IclR family compare
GFF102 -0.8 -2.6 General secretion pathway protein F compare
GFF143 -0.8 -1.7 Dethiobiotin synthase BioD (EC 6.3.3.3) compare
GFF6638 -0.8 -4.2 no description compare


Specific Phenotypes

None in this experiment

For Variovorax sp. SCN45 in vitamin experiments

For vitamin calcium pantothenate across organisms