Experiment set1S354 for Escherichia fergusonii Becca

Compare to:

BHIS_CaCl2 no phage control with stool-derived community from humanized mice (condition: pre-antibiotic, MAC-deficient diet, mouse 1)

200 most detrimental genes:

  gene name fitness t score description  
EFB2_03803 +2.3 2.6 hypothetical protein compare
EFB2_01954 +1.4 1.7 hypothetical protein compare
EFB2_02031 +1.3 1.5 hypothetical protein compare
EFB2_03747 +1.2 2.4 putative membrane protein YkgR compare
EFB2_01004 +1.1 1.7 FAD assembly factor SdhE compare
EFB2_02303 +1.0 2.8 hypothetical protein compare
EFB2_03801 +1.0 2.4 hypothetical protein compare
EFB2_02979 +0.9 2.6 Anti-FlhC(2)FlhD(4) factor YdiV compare
EFB2_02425 +0.9 2.9 PTS system N,N'-diacetylchitobiose-specific EIIC component compare
EFB2_01856 +0.9 0.7 hypothetical protein compare
EFB2_01647 +0.8 3.0 hypothetical protein compare
EFB2_01570 +0.8 1.9 hypothetical protein compare
EFB2_02530 +0.8 2.6 hypothetical protein compare
EFB2_02901 +0.8 2.4 Flagellar basal body rod protein FlgB compare
EFB2_03375 +0.8 2.7 hypothetical protein compare
EFB2_04018 +0.8 2.5 FKBP-type 16 kDa peptidyl-prolyl cis-trans isomerase compare
EFB2_02291 +0.8 2.8 Ferredoxin-like protein FixX compare
EFB2_02272 +0.7 1.8 hypothetical protein compare
EFB2_03934 +0.7 2.0 Colicin-E7 immunity protein compare
EFB2_01580 +0.7 2.4 NADH-quinone oxidoreductase subunit K compare
EFB2_01964 +0.7 0.8 hypothetical protein compare
EFB2_00706 +0.7 1.1 hypothetical protein compare
EFB2_03211 +0.7 1.2 hypothetical protein compare
EFB2_01838 +0.7 1.4 Antitoxin YefM compare
EFB2_02949 +0.7 2.7 hypothetical protein compare
EFB2_02759 +0.7 1.9 hypothetical protein compare
EFB2_04413 +0.7 2.0 Anti-FlhC(2)FlhD(4) factor YdiV compare
EFB2_00112 +0.7 2.0 hypothetical protein compare
EFB2_02761 +0.6 1.1 Outer membrane protein IcsA autotransporter compare
EFB2_02102 +0.6 2.3 DNA polymerase III subunit theta compare
EFB2_04224 +0.6 1.3 Hemolysin secretion protein D, chromosomal compare
EFB2_04781 +0.6 1.5 Ubiquinone biosynthesis accessory factor UbiJ compare
EFB2_02009 +0.6 2.4 Flagellar hook-basal body complex protein FliE compare
EFB2_02800 +0.6 2.6 hypothetical protein compare
EFB2_03042 +0.6 1.9 Galactarate dehydratase (L-threo-forming) compare
EFB2_01752 +0.6 1.3 hypothetical protein compare
EFB2_02426 +0.6 1.0 PTS system N,N'-diacetylchitobiose-specific EIIA component compare
EFB2_04236 +0.6 1.2 Inner membrane protein YphA compare
EFB2_02532 +0.6 1.6 hypothetical protein compare
EFB2_02651 +0.6 1.8 Protein YmiA compare
EFB2_02546 +0.6 1.4 hypothetical protein compare
EFB2_02490 +0.6 2.3 HTH-type transcriptional regulator PgrR compare
EFB2_01959 +0.6 1.5 hypothetical protein compare
EFB2_01380 +0.5 0.9 putative protein YfgJ compare
EFB2_01901 +0.5 2.0 IS3 family transposase IS1351 compare
EFB2_01712 +0.5 3.3 hypothetical protein compare
EFB2_04754 +0.5 1.7 hypothetical protein compare
EFB2_00312 +0.5 0.8 hypothetical protein compare
EFB2_02997 +0.5 2.5 Colicin V secretion protein CvaA compare
EFB2_03826 +0.5 1.7 hypothetical protein compare
EFB2_02257 +0.5 2.2 PTS system N,N'-diacetylchitobiose-specific EIIA component compare
EFB2_03767 +0.5 1.2 hypothetical protein compare
EFB2_02229 +0.5 2.1 Putative NAD(P)H nitroreductase YdjA compare
EFB2_04562 +0.5 0.6 Glycerol-3-phosphate acyltransferase compare
EFB2_02166 +0.5 1.7 Ribosomal RNA small subunit methyltransferase F compare
EFB2_00557 +0.5 2.0 hypothetical protein compare
EFB2_04849 +0.5 3.3 dTDP-fucosamine acetyltransferase compare
EFB2_02829 +0.5 0.6 hypothetical protein compare
EFB2_02164 +0.5 1.8 hypothetical protein compare
EFB2_02496 +0.5 1.3 Protein FimF compare
EFB2_04440 +0.5 1.3 hypothetical protein compare
EFB2_03802 +0.5 1.1 hypothetical protein compare
EFB2_02707 +0.4 1.6 Protein YchN compare
EFB2_02813 +0.4 1.5 hypothetical protein compare
EFB2_01235 +0.4 1.4 tRNA-Arg compare
EFB2_03771 +0.4 1.1 hypothetical protein compare
EFB2_01310 +0.4 1.1 hypothetical protein compare
EFB2_02765 +0.4 0.8 Inner membrane protein YmgF compare
EFB2_02792 +0.4 1.5 hypothetical protein compare
EFB2_02165 +0.4 2.0 putative protein YebV compare
EFB2_02981 +0.4 1.8 S-fimbrial adhesin protein SfaS compare
EFB2_02420 +0.4 0.6 Small protein MgtS compare
EFB2_02959 +0.4 1.5 hypothetical protein compare
EFB2_00629 +0.4 3.3 Intermembrane phospholipid transport system permease protein MlaE compare
EFB2_03027 +0.4 1.1 Acyl carrier protein compare
EFB2_00740 +0.4 1.4 Transcriptional regulator YqjI compare
EFB2_03427 +0.4 2.6 N-acetylglucosamine repressor compare
EFB2_02246 +0.4 2.6 Arginine N-succinyltransferase compare
EFB2_03999 +0.4 2.0 Glutathione-regulated potassium-efflux system ancillary protein KefF compare
EFB2_02398 +0.4 2.0 Protein mlc compare
EFB2_02772 +0.4 0.8 putative protein YdfO compare
EFB2_02948 +0.4 1.0 hypothetical protein compare
EFB2_01477 +0.4 1.7 hypothetical protein compare
EFB2_02191 +0.4 1.5 2-iminobutanoate/2-iminopropanoate deaminase compare
EFB2_02812 +0.4 0.6 Crossover junction endodeoxyribonuclease RusA compare
EFB2_01578 +0.4 1.3 NADH-quinone oxidoreductase subunit I compare
EFB2_02603 +0.4 1.6 Thiol peroxidase compare
EFB2_01972 +0.4 0.4 hypothetical protein compare
EFB2_02853 +0.4 1.0 Inner membrane protein YmfA compare
EFB2_01892 +0.4 2.1 hypothetical protein compare
EFB2_04489 +0.4 1.2 Aminoalkylphosphonate N-acetyltransferase compare
EFB2_02004 +0.4 1.6 Flagellar FliJ protein compare
EFB2_01857 +0.4 2.1 hypothetical protein compare
EFB2_01366 +0.4 0.9 Protein IscX compare
EFB2_02797 +0.4 1.6 hypothetical protein compare
EFB2_03002 +0.4 1.1 hypothetical protein compare
EFB2_01430 +0.3 2.2 Ethanolamine utilization protein EutD compare
EFB2_04620 +0.3 1.7 Sulfur carrier protein ThiS compare
EFB2_02001 +0.3 1.7 Flagellar motor switch protein FliM compare
EFB2_01872 +0.3 1.0 hypothetical protein compare
EFB2_04038 +0.3 1.8 hypothetical protein compare
EFB2_00431 +0.3 1.7 ADP compounds hydrolase NudE compare
EFB2_02335 +0.3 0.5 putative protein YnhF compare
EFB2_02578 +0.3 1.1 hypothetical protein compare
EFB2_00026 +0.3 1.2 hypothetical protein compare
EFB2_02768 +0.3 0.5 putative two-component-system connector protein AriR compare
EFB2_02122 +0.3 1.2 hypothetical protein compare
EFB2_03103 +0.3 1.1 Acylphosphatase compare
EFB2_04287 +0.3 1.7 Arginine repressor compare
EFB2_01441 +0.3 1.5 Ethanolamine utilization protein EutK compare
EFB2_03530 +0.3 1.1 hypothetical protein compare
EFB2_04454 +0.3 1.0 Toxin GhoT compare
EFB2_03038 +0.3 1.8 3-oxoacyl-[acyl-carrier-protein] reductase FabG compare
EFB2_02226 +0.3 2.0 Nicotinamidase compare
EFB2_01812 +0.3 2.2 UTP--glucose-1-phosphate uridylyltransferase compare
EFB2_02538 +0.3 0.9 putative protein YdcY compare
EFB2_01977 +0.3 1.2 Metal-binding protein ZinT compare
EFB2_03307 +0.3 1.0 N-glycosidase YbiA compare
EFB2_00210 +0.3 1.5 putative protein YibL compare
EFB2_01658 +0.3 1.2 Heme exporter protein D compare
EFB2_02619 +0.3 1.1 Thiosulfate sulfurtransferase PspE compare
EFB2_02767 +0.3 0.5 putative protein YmgC compare
EFB2_02837 +0.3 0.7 hypothetical protein compare
EFB2_00882 +0.3 1.4 hypothetical protein compare
EFB2_04482 +0.3 1.4 Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnH compare
EFB2_00200 +0.3 2.1 Glutaredoxin 3 compare
EFB2_01943 +0.3 2.0 Vitamin B12 import ATP-binding protein BtuD compare
EFB2_02872 +0.3 1.0 Purine nucleoside phosphoramidase compare
EFB2_03047 +0.3 1.7 D-tagatose-1,6-bisphosphate aldolase subunit KbaY compare
EFB2_00976 +0.3 2.0 hypothetical protein compare
EFB2_02811 +0.3 0.7 putative protein YlcG compare
EFB2_00185 +0.3 1.2 hypothetical protein compare
EFB2_04598 +0.3 1.9 Peptidyl-lysine N-acetyltransferase YjaB compare
EFB2_02247 +0.3 1.6 N-succinylglutamate 5-semialdehyde dehydrogenase compare
EFB2_00103 +0.3 0.9 putative protein YbdM compare
EFB2_01969 +0.3 0.6 hypothetical protein compare
EFB2_03460 +0.3 2.1 D-alanyl-D-alanine carboxypeptidase DacA compare
EFB2_00005 +0.3 1.2 hypothetical protein compare
EFB2_03467 +0.3 1.3 Putative fluoride ion transporter CrcB compare
EFB2_04097 +0.3 1.4 hypothetical protein compare
EFB2_03455 +0.3 1.2 Ribosomal silencing factor RsfS compare
EFB2_01577 +0.3 0.7 NADH-quinone oxidoreductase subunit H compare
EFB2_03731 +0.3 1.6 hypothetical protein compare
EFB2_00304 +0.3 1.4 hypothetical protein compare
EFB2_01664 +0.3 1.5 hypothetical protein compare
EFB2_03026 +0.3 0.8 hypothetical protein compare
EFB2_03403 +0.3 0.8 hypothetical protein compare
EFB2_02250 +0.3 0.7 Periplasmic chaperone Spy compare
EFB2_01050 +0.3 1.2 putative lipoprotein YgdR compare
EFB2_02635 +0.3 1.5 HTH-type transcriptional regulator BetI compare
EFB2_01997 +0.3 1.0 Flagellar biosynthetic protein FliQ compare
EFB2_04850 +0.3 2.1 Glucose-1-phosphate thymidylyltransferase 2 compare
EFB2_02833 +0.3 0.9 hypothetical protein compare
EFB2_00861 +0.3 1.5 hypothetical protein compare
EFB2_02357 +0.3 1.3 Glutathione S-transferase GstA compare
EFB2_03814 +0.3 0.9 hypothetical protein compare
EFB2_00097 +0.3 0.5 Hemolysin-activating lysine-acyltransferase HlyC compare
EFB2_00975 +0.3 1.3 Energy-coupling factor transporter ATP-binding protein EcfA1 compare
EFB2_01929 +0.3 1.2 putative transcriptional regulatory protein YeeN compare
EFB2_02667 +0.3 0.8 Protein YciF compare
EFB2_02220 +0.3 1.5 putative zinc-type alcohol dehydrogenase-like protein YdjJ compare
EFB2_02194 +0.3 1.3 Outer membrane protein Slp compare
EFB2_01818 +0.3 0.3 UDP-Glc:alpha-D-GlcNAc-diphosphoundecaprenol beta-1,3-glucosyltransferase WfgD compare
EFB2_02131 +0.3 1.1 hypothetical protein compare
EFB2_03602 +0.3 1.2 putative protein YbaA compare
EFB2_01721 +0.3 2.1 D-alanyl-D-alanine endopeptidase compare
EFB2_02237 +0.3 1.1 Fe(3+) ions import ATP-binding protein FbpC 2 compare
EFB2_00595 +0.3 0.9 Serine endoprotease DegS compare
EFB2_03106 +0.3 1.0 putative protein YccU compare
EFB2_01748 +0.3 1.1 putative fimbrial-like protein YehA compare
EFB2_01305 +0.3 1.4 IS3 family transposase IS1397 compare
EFB2_01545 +0.3 1.4 Colicin V production protein compare
EFB2_02271 +0.3 0.8 putative protein YniD compare
EFB2_00642 +0.3 0.9 Transcription elongation factor GreA compare
EFB2_02168 +0.3 2.0 Intermembrane transport protein YebS compare
EFB2_02382 +0.3 1.4 DNA replication terminus site-binding protein compare
EFB2_03775 +0.3 1.1 hypothetical protein compare
EFB2_02791 +0.3 1.1 hypothetical protein compare
EFB2_03185 +0.3 2.0 hypothetical protein compare
EFB2_01068 +0.3 0.7 Transcription antiterminator LicT compare
EFB2_02101 +0.3 1.5 hypothetical protein compare
EFB2_02977 +0.3 1.6 IS630 family transposase ISEc40 compare
EFB2_03800 +0.3 0.6 hypothetical protein compare
EFB2_00309 +0.3 1.9 Hemin transport protein HemS compare
EFB2_03377 +0.3 1.1 Succinate--CoA ligase [ADP-forming] subunit alpha compare
EFB2_03043 +0.3 1.1 Galactarate dehydratase (L-threo-forming) compare
EFB2_03032 +0.3 1.0 1,4-dihydroxy-2-naphthoyl-CoA hydrolase compare
EFB2_02163 +0.3 1.5 Serine/threonine-protein phosphatase 1 compare
EFB2_02704 +0.3 1.8 Nitrate/nitrite sensor protein NarX compare
EFB2_04024 +0.3 1.8 Na(+)/H(+) antiporter NhaA compare
EFB2_02212 +0.3 1.8 MltA-interacting protein compare
EFB2_00453 +0.3 1.2 hypothetical protein compare
EFB2_04105 +0.3 1.5 hypothetical protein compare
EFB2_02325 +0.3 0.6 Putative monooxygenase YdhR compare
EFB2_04773 +0.3 1.8 NAD(P)H-flavin reductase compare
EFB2_03181 +0.2 1.0 Cold shock-like protein CspD compare
EFB2_03385 +0.2 0.8 Protein YbgU compare
EFB2_04481 +0.2 1.2 Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG compare
EFB2_02560 +0.2 0.9 hypothetical protein compare
EFB2_00450 +0.2 1.4 hypothetical protein compare


Specific Phenotypes

None in this experiment

For Escherichia fergusonii Becca in mixed community no phage control experiments

For mixed community no phage control stool-derived community from humanized mice (condition: pre-antibiotic, MAC-deficient diet, mouse 1) across organisms