Experiment set1S319 for Hydrogenophaga sp. GW460-11-11-14-LB1

Compare to:

Ying_Nucleobase14 rep A; time point 2

200 most detrimental genes:

  gene name fitness t score description  
GFF1267 +2.7 21.3 Protein-N(5)-glutamine methyltransferase PrmC, methylates polypeptide chain release factors RF1 and RF2 compare
GFF1225 +2.5 4.7 FIG136845: Rhodanese-related sulfurtransferase compare
GFF3853 +2.1 5.3 DNA-binding protein HU-beta compare
GFF4211 +1.9 13.6 Dihydroorotate dehydrogenase (EC 1.3.3.1) compare
GFF2763 +1.9 8.1 Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23) compare
GFF5491 +1.7 7.2 tRNA dimethylallyltransferase (EC 2.5.1.75) compare
GFF4564 +1.6 10.2 Methionine aminopeptidase (EC 3.4.11.18) compare
GFF651 +1.6 10.9 Aspartate carbamoyltransferase (EC 2.1.3.2) compare
GFF4851 +1.6 8.2 Xanthine-guanine phosphoribosyltransferase (EC 2.4.2.22) compare
GFF1882 +1.5 11.6 Orotate phosphoribosyltransferase (EC 2.4.2.10) compare
GFF371 +1.5 11.2 MgtC family compare
GFF1272 +1.4 12.7 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
GFF3040 +1.4 9.8 Malate synthase G (EC 2.3.3.9) compare
GFF4226 +1.3 11.9 Polyphosphate kinase (EC 2.7.4.1) compare
GFF4670 +1.3 8.8 Molybdenum transport system permease protein ModB (TC 3.A.1.8.1) compare
GFF2435 +1.3 6.4 Protein YidD compare
GFF3654 +1.2 2.3 FIG138315: Putative alpha helix protein compare
GFF4044 +1.2 10.8 ATP-dependent protease La (EC 3.4.21.53) Type I compare
GFF5265 +1.2 4.8 hypothetical protein compare
GFF206 +1.1 8.6 Nucleoside ABC transporter, permease protein 1 compare
GFF5742 +1.1 4.0 Probable transmembrane protein compare
GFF2410 +1.1 2.1 Two-component system response regulator QseB compare
GFF4874 +1.1 9.7 ATPase component BioM of energizing module of biotin ECF transporter compare
GFF385 +1.1 9.7 B12 binding domain / kinase domain / Methylmalonyl-CoA mutase (EC 5.4.99.2) compare
GFF695 +1.1 7.2 Cytochrome oxidase biogenesis protein Surf1, facilitates heme A insertion compare
GFF4043 +1.1 8.8 ATP-dependent Clp protease ATP-binding subunit ClpX compare
GFF699 +1.1 6.3 Cytochrome oxidase biogenesis protein Sco1/SenC/PrrC, putative copper metallochaperone compare
GFF1913 +1.1 2.6 Permease of the drug/metabolite transporter (DMT) superfamily compare
GFF2671 +1.1 3.1 hypothetical protein compare
GFF3886 +1.1 4.7 Protein GlcG compare
GFF1194 +1.0 1.8 Formate dehydrogenase subunit or accessory protein compare
GFF2533 +1.0 8.0 Glutamate-ammonia-ligase adenylyltransferase (EC 2.7.7.42) compare
GFF4864 +1.0 2.3 FIG021952: putative membrane protein compare
GFF4669 +1.0 8.1 Molybdenum ABC transporter, periplasmic molybdenum-binding protein ModA (TC 3.A.1.8.1) compare
GFF767 +1.0 2.7 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
GFF4284 +1.0 8.4 Arginine-tRNA-protein transferase (EC 2.3.2.8) compare
GFF696 +1.0 6.5 Probable transmembrane protein compare
GFF208 +0.9 6.1 Nucleoside ABC transporter, periplasmic nucleoside-binding protein compare
GFF5032 +0.9 2.0 Glyoxalase/bleomycin resistance protein (EC 4.4.1.5) compare
GFF676 +0.9 6.5 Putative periplasmic cytochrome type-C oxidoreductase signal peptide protein (EC 1.-.-.-) compare
GFF366 +0.9 2.4 Probable transmembrane protein compare
GFF4671 +0.9 4.8 Molybdenum transport ATP-binding protein ModC (TC 3.A.1.8.1) compare
GFF600 +0.9 1.4 Phosphohydrolase (MutT/nudix family protein) compare
GFF4417 +0.9 1.5 Electron transfer flavoprotein, beta subunit compare
GFF207 +0.9 6.4 Nucleoside ABC transporter, permease protein 2 compare
GFF3485 +0.8 2.1 Plasmid replication initiator protein compare
GFF4297 +0.8 2.1 FIG001341: Probable Fe(2+)-trafficking protein YggX compare
GFF468 +0.8 2.2 Ribose ABC transport system, permease protein RbsC (TC 3.A.1.2.1) compare
GFF2954 +0.8 6.8 Cytochrome c5 compare
GFF205 +0.8 4.4 ABC transporter ATP-binding protein compare
GFF120 +0.8 3.1 Ribonuclease E (EC 3.1.26.12) compare
GFF1575 +0.8 2.3 Nudix-related transcriptional regulator NrtR compare
GFF917 +0.8 2.8 Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4) compare
GFF2176 +0.8 1.8 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
GFF4769 +0.8 5.5 FIG070318: hypothetical protein compare
GFF4809 +0.8 5.8 MutT/nudix family protein compare
GFF4520 +0.8 3.9 ATP-dependent Clp protease adaptor protein ClpS compare
GFF1932 +0.8 1.5 Bll5738 protein compare
GFF4252 +0.8 4.3 FIG000557: hypothetical protein co-occurring with RecR compare
GFF5396 +0.7 2.4 amino acid ABC transporter, periplasmic substrate-binding protein compare
GFF3496 +0.7 1.4 Mlr6156 protein compare
GFF573 +0.7 2.5 Phosphatidate cytidylyltransferase (EC 2.7.7.41) compare
GFF2567 +0.7 3.5 Preprotein translocase subunit YajC (TC 3.A.5.1.1) compare
GFF3385 +0.7 1.1 hypothetical protein PA3071 compare
GFF697 +0.7 3.6 Heme A synthase, cytochrome oxidase biogenesis protein Cox15-CtaA compare
GFF4866 +0.7 3.7 Ribosomal RNA large subunit methyltransferase N (EC 2.1.1.-) compare
GFF323 +0.7 2.6 Probable sulfite reductase compare
GFF2595 +0.7 1.2 hypothetical protein compare
GFF2166 +0.7 1.5 Alcohol dehydrogenase (EC 1.1.1.1) compare
GFF3628 +0.7 1.3 Ornithine cyclodeaminase (EC 4.3.1.12) compare
GFF4897 +0.7 5.3 Transcription elongation factor GreA compare
GFF677 +0.7 1.1 FIG00433688: hypothetical protein compare
GFF353 +0.7 1.4 Organic hydroperoxide resistance protein compare
GFF933 +0.7 1.7 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100) compare
GFF1698 +0.7 1.1 Ferredoxin compare
GFF513 +0.7 1.8 Enoyl-CoA hydratase (EC 4.2.1.17) compare
GFF2877 +0.7 1.3 Methylglyoxal reductase, acetol producing (EC 1.1.1.-) / 2,5-diketo-D-gluconic acid reductase B (EC 1.1.1.274) compare
GFF343 +0.7 1.8 tRNA pseudouridine synthase A (EC 4.2.1.70) compare
GFF463 +0.7 1.1 Transcriptional regulator, GntR family compare
GFF5018 +0.7 1.5 Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) compare
GFF737 +0.6 3.3 Autolysin sensor kinase (EC 2.7.3.-) compare
GFF1556 +0.6 1.5 Succinate-semialdehyde dehydrogenase [NAD(P)+] (EC 1.2.1.16) compare
GFF4152 +0.6 2.0 FIG050068: DNA-binding protein compare
GFF3400 +0.6 1.6 High-affinity branched-chain amino acid transport system permease protein LivH (TC 3.A.1.4.1) compare
GFF5806 +0.6 1.1 tRNA-Ala-CGC compare
GFF3402 +0.6 1.0 Branched-chain amino acid transport ATP-binding protein LivG (TC 3.A.1.4.1) compare
GFF4023 +0.6 1.2 PUTATIVE METHYLTRANSFERASE compare
GFF521 +0.6 2.2 Glutamate Aspartate transport system permease protein GltK (TC 3.A.1.3.4) compare
GFF5477 +0.6 1.5 Probable ferredoxin subunit of a ring-hydroxylating dioxygenase oxidoreductase protein (EC 1.-.-.-) compare
GFF210 +0.6 4.3 Adenosine deaminase (EC 3.5.4.4) compare
GFF123 +0.6 4.3 Low molecular weight protein tyrosine phosphatase (EC 3.1.3.48) compare
GFF1924 +0.6 0.9 MG(2+) CHELATASE FAMILY PROTEIN / ComM-related protein compare
GFF2440 +0.6 3.3 Adenine phosphoribosyltransferase (EC 2.4.2.7) compare
GFF450 +0.6 1.2 PhnB protein compare
GFF4760 +0.6 3.8 hypothetical protein compare
GFF3887 +0.6 3.1 hypothetical protein compare
GFF5128 +0.6 1.7 Tricarboxylate transport protein TctB compare
GFF2192 +0.6 3.4 Cys regulon transcriptional activator CysB compare
GFF2515 +0.6 4.1 Phosphoenolpyruvate synthase (EC 2.7.9.2) compare
GFF519 +0.6 2.5 Glutamate Aspartate periplasmic binding protein precursor GltI (TC 3.A.1.3.4) compare
GFF796 +0.6 1.3 TRAP-type C4-dicarboxylate transport system, small permease component compare
GFF4841 +0.6 1.1 Antiholin-like protein LrgA compare
GFF121 +0.6 4.5 Ribosomal large subunit pseudouridine synthase C (EC 4.2.1.70) compare
GFF518 +0.6 1.8 Transcriptional regulator compare
GFF845 +0.6 1.6 Prevent host death protein, Phd antitoxin # C compare
GFF4759 +0.6 4.9 Polysaccharide biosynthesis protein compare
GFF1037 +0.6 4.1 Esterase/lipase compare
GFF4865 +0.6 3.5 Type IV pilus biogenesis protein PilF compare
GFF2428 +0.6 1.6 TRAP-type C4-dicarboxylate transport system, small permease component compare
GFF4939 +0.6 3.1 D-amino acid dehydrogenase small subunit (EC 1.4.99.1) compare
GFF4004 +0.6 1.1 LysR family regulatory protein compare
GFF2996 +0.6 1.0 hypothetical protein compare
GFF4794 +0.6 3.5 TrkA-N:Sodium/hydrogen exchanger compare
GFF4773 +0.6 4.0 Protein-tyrosine kinase (EC 2.7.1.112) compare
GFF2017 +0.6 4.4 rRNA small subunit 7-methylguanosine (m7G) methyltransferase GidB compare
GFF2713 +0.6 1.4 Aminopeptidase Y (Arg, Lys, Leu preference) (EC 3.4.11.15) compare
GFF405 +0.6 3.1 hypothetical protein compare
GFF4084 +0.6 1.8 ubiquinone/menaquinone biosynthesis methyltransferase compare
GFF4262 +0.6 3.3 Molybdopterin biosynthesis protein MoeA compare
GFF342 +0.6 2.2 transcriptional regulator, Crp/Fnr family compare
GFF2563 +0.6 1.5 hypothetical protein compare
GFF3522 +0.6 1.2 Sensory histidine kinase QseC compare
GFF781 +0.6 1.0 Branched-chain amino acid transport ATP-binding protein LivF (TC 3.A.1.4.1) compare
GFF3602 +0.6 1.5 hypothetical protein compare
GFF4014 +0.6 1.4 DUF1232 domain-containing protein compare
GFF1041 +0.6 2.0 Aerotaxis sensor receptor protein compare
GFF487 +0.6 3.4 Cobalt-zinc-cadmium resistance protein CzcA; Cation efflux system protein CusA compare
GFF4830 +0.5 1.1 Histone acetyltransferase HPA2 and related acetyltransferases compare
GFF253 +0.5 1.1 cytochrome c subunit of flavocytochrome c sulfide dehydrogenase compare
GFF634 +0.5 3.7 tRNA dihydrouridine synthase B (EC 1.-.-.-) compare
GFF3378 +0.5 2.1 transcriptional regulator, XRE family compare
GFF2867 +0.5 1.3 hypothetical protein compare
GFF83 +0.5 1.6 Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid compare
GFF4034 +0.5 1.3 Chromosome initiation inhibitor compare
GFF1524 +0.5 1.4 putative exported protein compare
GFF892 +0.5 2.3 Aspartate 1-decarboxylase (EC 4.1.1.11) compare
GFF3561 +0.5 4.5 Glutamate--cysteine ligase (EC 6.3.2.2) compare
GFF5781 +0.5 2.4 hypothetical protein compare
GFF3151 +0.5 1.3 hypothetical protein compare
GFF5775 +0.5 3.2 Permease of the drug/metabolite transporter (DMT) superfamily compare
GFF4435 +0.5 0.8 Conjugative transfer protein TrbB compare
GFF5391 +0.5 1.9 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100) compare
GFF2276 +0.5 2.3 hypothetical protein compare
GFF5428 +0.5 3.0 FIG002343: hypothetical protein compare
GFF544 +0.5 1.4 hypothetical protein compare
GFF698 +0.5 2.5 Heme O synthase, protoheme IX farnesyltransferase (EC 2.5.1.-) COX10-CtaB compare
GFF2139 +0.5 1.0 transcriptional regulator, LysR family compare
GFF1351 +0.5 4.2 Cytochrome c4 compare
GFF5159 +0.5 2.3 Type IV pilus biogenesis protein PilE compare
GFF3405 +0.5 0.8 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100) compare
GFF5140 +0.5 2.8 DNA-3-methyladenine glycosylase II (EC 3.2.2.21) compare
GFF5676 +0.5 2.5 NAD(P)H oxidoreductase YRKL (EC 1.6.99.-) @ Putative NADPH-quinone reductase (modulator of drug activity B) @ Flavodoxin 2 compare
GFF5030 +0.5 2.3 Alkanesulfonates-binding protein compare
GFF4424 +0.5 0.9 Regulatory protein, LuxR:Tetratricopeptide TPR_4 compare
GFF3523 +0.5 2.3 Two-component system response regulator QseB compare
GFF4090 +0.5 1.3 Flagellar biosynthesis protein FliQ compare
GFF5602 +0.5 1.0 Inositol transport system sugar-binding protein compare
GFF1224 +0.5 3.5 Glutaredoxin 3 (Grx3) compare
GFF1706 +0.5 0.8 YbaK/prolyl-tRNA synthetase associated region compare
GFF413 +0.5 1.4 FIG00581832: hypothetical protein compare
GFF923 +0.5 1.9 Butyryl-CoA dehydrogenase (EC 1.3.99.2) compare
GFF4768 +0.5 3.2 FIG137776: Glycosyltransferase compare
GFF4775 +0.5 3.8 FIG123464: Polysaccharide export protein compare
GFF3083 +0.5 2.8 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) compare
GFF4764 +0.5 2.9 Glycosyltransferase compare
GFF4316 +0.5 0.5 Phenylacetic acid degradation protein PaaN, ring-opening aldehyde dehydrogenase (EC 1.2.1.3) compare
GFF2905 +0.5 2.7 Branched-chain amino acid transport ATP-binding protein LivF (TC 3.A.1.4.1) compare
GFF652 +0.5 1.6 Dihydroorotase (EC 3.5.2.3) compare
GFF5489 +0.5 1.0 TPR domain protein, putative component of TonB system compare
GFF3453 +0.5 1.2 Conjugative transfer protein TrbB compare
GFF5578 +0.5 4.0 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit compare
GFF4065 +0.5 1.6 RNA polymerase sigma factor for flagellar operon compare
GFF1006 +0.5 2.4 hypothetical protein compare
GFF5526 +0.5 2.8 TRAP-type C4-dicarboxylate transport system, large permease component compare
GFF4331 +0.5 3.2 Putative activity regulator of membrane protease YbbK compare
GFF340 +0.5 3.4 Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) compare
GFF1982 +0.5 1.9 Nitrilotriacetate monooxygenase component B (EC 1.14.13.-) compare
GFF1217 +0.5 1.8 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
GFF4997 +0.5 1.9 Tricarboxylate transport protein TctC compare
GFF2687 +0.5 1.4 putative exported protein compare
GFF4499 +0.5 1.7 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
GFF2758 +0.5 1.8 Adenylate cyclase (EC 4.6.1.1) compare
GFF1232 +0.5 1.5 hypothetical protein compare
GFF339 +0.5 1.7 Branched-chain amino acid transport ATP-binding protein LivG (TC 3.A.1.4.1) compare
GFF806 +0.5 2.1 Homoserine dehydrogenase (EC 1.1.1.3) compare
GFF1335 +0.5 3.1 Type IV pilus biogenesis protein PilO compare
GFF5658 +0.5 1.2 Methylsuccinyl-CoA dehydrogenase, predicted by (Erb et al, 2007) compare
GFF3425 +0.4 1.8 Nucleoside-diphosphate-sugar epimerases compare
GFF4258 +0.4 2.6 FIG005121: SAM-dependent methyltransferase (EC 2.1.1.-) compare
GFF145 +0.4 1.3 Methyl-accepting chemotaxis protein compare
GFF3070 +0.4 1.0 FIG00348512: hypothetical protein compare
GFF5003 +0.4 0.7 Adenylate cyclase (EC 4.6.1.1) compare
GFF5399 +0.4 2.4 autotransporter compare
GFF3973 +0.4 2.1 hypothetical protein compare
GFF3752 +0.4 0.7 Hydroxymethylpyrimidine ABC transporter, ATPase component compare
GFF2558 +0.4 1.4 hypothetical protein compare
GFF3262 +0.4 2.5 Urease accessory protein UreG compare
GFF1577 +0.4 0.8 YciL protein compare
GFF3395 +0.4 0.9 Enoyl-CoA hydratase (EC 4.2.1.17) compare
GFF2878 +0.4 1.4 Two-component response regulator compare


Specific Phenotypes

None in this experiment

For Hydrogenophaga sp. GW460-11-11-14-LB1 in carbon source experiments

For carbon source Ying_Nucleobase14 across organisms