Experiment set1S185 for Escherichia coli ECOR27

Compare to:

Control_ECOR27

200 most detrimental genes:

  gene name fitness t score description  
NOLOHH_09630 sspA +3.0 5.6 stringent starvation protein A compare
NOLOHH_03935 fimE +2.6 8.9 type 1 fimbria switch DNA invertase FimE compare
NOLOHH_12310 rpoS +2.4 10.9 RNA polymerase sigma factor RpoS compare
NOLOHH_12305 nlpD +1.1 5.5 murein hydrolase activator NlpD compare
NOLOHH_15730 +0.9 4.1 N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,o ctacis-undecaprenol 4-epimerase compare
NOLOHH_06715 wecA +0.9 7.0 UDP-N-acetylglucosamine--undecaprenyl-phosphate N-acetylglucosaminephosphotransferase compare
NOLOHH_10295 cfaA +0.9 1.4 colonisation factor antigen a, chaperone compare
NOLOHH_13285 iscR +0.9 1.9 Fe-S cluster assembly transcriptional regulator IscR compare
NOLOHH_12875 dgcN +0.9 1.8 diguanylate cyclase DgcN compare
NOLOHH_23145 galE +0.8 1.8 UDP-glucose 4-epimerase GalE compare
NOLOHH_13785 ypeA +0.8 2.2 GNAT family acetyltransferase compare
NOLOHH_11810 kduD +0.8 3.5 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase KduD compare
NOLOHH_23920 ybdD +0.8 2.4 Uncharacterized protein YbdD compare
NOLOHH_06860 rbsR +0.8 4.6 ribose operon transcriptional repressor RbsR compare
NOLOHH_21260 pyrC +0.8 1.9 dihydroorotase compare
NOLOHH_09795 mlaC +0.8 3.2 phospholipid-binding protein MlaC compare
NOLOHH_23795 cspE +0.7 1.3 transcription antiterminator/RNA stability regulator CspE compare
NOLOHH_17100 yoaA +0.7 2.6 putative ATP-dependent DNA helicase YoaA compare
NOLOHH_14570 menB +0.7 2.4 1,4-dihydroxy-2-naphthoyl-CoA synthase compare
NOLOHH_03655 yjjQ +0.7 2.0 Putative transcription factor YjjQ compare
NOLOHH_14545 elaA +0.7 2.2 GNAT family N-acetyltransferase compare
NOLOHH_15905 yeeA +0.7 1.8 Inner membrane protein YeeA compare
NOLOHH_23780 tatE +0.7 2.3 deaminated glutathione amidase compare
NOLOHH_14875 ccmE +0.7 1.8 cytochrome c maturation protein CcmE compare
NOLOHH_15050 nupX +0.7 1.7 Putative nucleoside permease NupX compare
NOLOHH_14285 yfcJ +0.7 2.2 Uncharacterized MFS-type transporter YfcJ compare
NOLOHH_17340 topB +0.7 1.8 DNA topoisomerase III compare
NOLOHH_03610 rimI +0.7 3.9 ribosomal protein S18-alanine N-acetyltransferase compare
NOLOHH_12610 luxS +0.7 2.0 S-ribosylhomocysteine lyase compare
NOLOHH_23360 fimC +0.7 2.3 molecular chaperone compare
NOLOHH_22290 artM +0.7 2.4 arginine ABC transporter permease ArtM compare
NOLOHH_21230 yceM +0.7 1.7 Putative oxidoreductase YceM compare
NOLOHH_15735 galF +0.7 1.9 UTP--glucose-1-phosphate uridylyltransferase GalF compare
NOLOHH_24270 psiA +0.7 1.6 Protein PsiA compare
NOLOHH_17335 selD +0.6 1.7 selenide, water dikinase SelD compare
NOLOHH_22305 rlmC +0.6 1.9 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC compare
NOLOHH_12005 ygdD +0.6 2.0 UPF0382 inner membrane protein YgdD compare
NOLOHH_16745 znuA +0.6 2.1 zinc ABC transporter substrate-binding protein ZnuA compare
NOLOHH_14375 yfcH +0.6 1.3 Epimerase family protein YfcH compare
NOLOHH_10260 yqjE +0.6 2.8 Inner membrane protein YqjE compare
NOLOHH_23855 rna +0.6 2.3 ribonuclease I compare
NOLOHH_14070 yfdY +0.6 1.9 Uncharacterized protein YfdY compare
NOLOHH_22345 nfsA +0.6 2.0 nitroreductase NfsA compare
NOLOHH_09525 yhdE +0.6 2.7 nucleoside triphosphate pyrophosphatase YhdE compare
NOLOHH_23020 +0.6 1.3 hypothetical protein compare
NOLOHH_21180 flgG +0.6 1.7 flagellar basal-body rod protein FlgG compare
NOLOHH_22680 ybhP +0.6 1.5 Uncharacterized protein YbhP compare
NOLOHH_03370 mokC +0.6 1.1 Regulatory protein MokC compare
NOLOHH_10775 yghW +0.6 2.0 Uncharacterized protein YghW compare
NOLOHH_22415 gstB +0.6 2.0 glutathione S-transferase GstB compare
NOLOHH_16970 proQ +0.6 1.6 RNA chaperone ProQ compare
NOLOHH_16410 tcyJ +0.6 2.0 cystine ABC transporter substrate-binding protein compare
NOLOHH_14005 yfeO +0.6 2.4 ion channel protein compare
NOLOHH_07945 hokA +0.6 1.3 type I toxin-antitoxin system toxin HokA compare
NOLOHH_21145 rluC +0.6 2.2 23S rRNA pseudouridine(955/2504/2580) synthase RluC compare
NOLOHH_14660 glpB +0.6 1.6 glycerol-3-phosphate dehydrogenase subunit GlpB compare
NOLOHH_15805 hisF +0.6 1.3 Imidazole glycerol phosphate synthase subunit HisF compare
NOLOHH_19950 ynaJ +0.6 1.7 Uncharacterized protein YnaJ compare
NOLOHH_06865 rbsK +0.6 3.9 ribokinase compare
NOLOHH_13965 yfeC +0.6 1.9 Uncharacterized protein YfeC compare
NOLOHH_15575 ibsA +0.6 1.6 Small toxic protein IbsA compare
NOLOHH_16255 yedQ +0.6 1.8 cellulose biosynthesis regulator YedQ compare
NOLOHH_06245 +0.6 1.6 Uncharacterized protein YshB compare
NOLOHH_21700 hyaD +0.6 1.6 hydrogenase 1 maturation protease compare
NOLOHH_12710 ygaV +0.6 1.4 putative HTH-type transcriptional regulator YgaV compare
NOLOHH_15630 wza +0.6 1.6 polysaccharide export protein Wza compare
NOLOHH_19920 abgA +0.5 1.4 p-aminobenzoyl-glutamate hydrolase subunit AbgA compare
NOLOHH_23165 gpmA +0.5 1.4 2,3-diphosphoglycerate-dependent phosphoglycerate mutase compare
NOLOHH_20445 adhE +0.5 2.0 bifunctional acetaldehyde-CoA/alcohol dehydrogenase compare
NOLOHH_02465 yaeR +0.5 1.6 VOC family protein compare
NOLOHH_03880 uxuR +0.5 1.8 Uxu operon transcriptional regulator compare
NOLOHH_18000 slyB +0.5 2.4 outer membrane lipoprotein SlyB compare
NOLOHH_18090 ydgJ +0.5 1.5 Uncharacterized oxidoreductase YdgJ compare
NOLOHH_16040 cobS +0.5 1.9 adenosylcobinamide-GDP ribazoletransferase compare
NOLOHH_00670 +0.5 1.6 Replication protein compare
NOLOHH_04180 cybC +0.5 1.3 cytochrome b562 compare
NOLOHH_03640 yjjZ +0.5 1.5 Uncharacterized protein YjjZ compare
NOLOHH_23385 pxpC +0.5 2.1 5-oxoprolinase subunit PxpC compare
NOLOHH_07585 yibB +0.5 2.3 protein YibB compare
NOLOHH_21245 mdtH +0.5 1.8 multidrug efflux MFS transporter MdtH compare
NOLOHH_22055 ycaP +0.5 1.4 UPF0702 transmembrane protein YcaP compare
NOLOHH_05535 thiF +0.5 1.6 thiazole biosynthesis adenylyltransferase ThiF compare
NOLOHH_01350 yajL +0.5 1.6 protein deglycase YajL compare
NOLOHH_11865 ygdR +0.5 1.3 lipoprotein YgdR compare
NOLOHH_22355 grxA +0.5 1.7 glutaredoxin 1 compare
NOLOHH_12440 hycF +0.5 1.6 formate hydrogenlyase subunit HycF compare
NOLOHH_15835 hisG +0.5 1.0 ATP phosphoribosyltransferase compare
NOLOHH_09660 nanE +0.5 1.8 Putative N-acetylmannosamine-6-phosphate 2-epimerase compare
NOLOHH_01555 iraP +0.5 1.6 anti-adapter protein IraP compare
NOLOHH_16680 yecE +0.5 1.3 UPF0759 protein YecE compare
NOLOHH_02080 prfH +0.5 1.4 peptide chain release factor H compare
NOLOHH_09635 sspB +0.5 2.8 ClpXP protease specificity-enhancing factor compare
NOLOHH_21985 elyC +0.5 1.6 envelope biogenesis factor ElyC compare
NOLOHH_24255 yubO +0.5 1.3 Uncharacterized protein YubO compare
NOLOHH_13815 murQ +0.5 2.1 N-acetylmuramic acid 6-phosphate etherase compare
NOLOHH_16415 dcyD +0.5 1.2 D-cysteine desulfhydrase compare
NOLOHH_04240 chpB +0.5 1.1 type II toxin-antitoxin system ChpB family toxin compare
NOLOHH_11115 yggU +0.5 1.9 DUF167 domain-containing protein compare
NOLOHH_00930 +0.5 1.3 Transposase (Identified by ISEscan HMM) compare
NOLOHH_04615 +0.5 1.5 Fumarate reductase subunit C compare
NOLOHH_23880 +0.5 1.5 Alkyl hydroperoxide reductase subunit F compare
NOLOHH_01610 tauD +0.5 1.9 taurine dioxygenase compare
NOLOHH_14575 menC +0.5 2.0 o-succinylbenzoate synthase compare
NOLOHH_15170 yohF +0.5 1.6 SDR family oxidoreductase compare
NOLOHH_22450 gsiC +0.5 2.3 glutathione ABC transporter permease GsiC compare
NOLOHH_22365 ybjL +0.5 2.0 aspartate:alanine antiporter compare
NOLOHH_07675 yibL +0.5 1.6 YibL family ribosome-associated protein compare
NOLOHH_09320 rsmB +0.5 1.2 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB compare
NOLOHH_14195 fadJ +0.5 2.1 fatty acid oxidation complex subunit alpha FadJ compare
NOLOHH_07475 pyrL +0.5 1.3 Putative PyrE leader peptide compare
NOLOHH_10575 ygiL +0.5 1.8 fimbrial-like protein compare
NOLOHH_24780 trbC +0.5 1.1 type-F conjugative transfer system pilin assembly protein TrbC compare
NOLOHH_22770 bioB +0.5 1.0 biotin synthase BioB compare
NOLOHH_09485 yhdT +0.5 1.2 Uncharacterized membrane protein YhdT compare
NOLOHH_20890 rluE +0.5 1.5 23S rRNA pseudouridine(2457) synthase RluE compare
NOLOHH_05730 argC +0.5 2.6 N-acetyl-gamma-glutamyl-phosphate reductase compare
NOLOHH_08550 livG +0.5 1.1 high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivG compare
NOLOHH_13550 hyfC +0.4 1.4 hydrogenase 4 subunit HyfC compare
NOLOHH_14820 napF +0.4 1.2 ferredoxin-type protein NapF compare
NOLOHH_21240 rimJ +0.4 1.7 ribosomal protein S5-alanine N-acetyltransferase compare
NOLOHH_22225 lysO +0.4 1.4 L-lysine exporter LysO compare
NOLOHH_21775 yccS +0.4 2.5 Inner membrane protein YccS compare
NOLOHH_03695 lgoR +0.4 2.3 putative HTH-type transcriptional regulator LgoR compare
NOLOHH_14805 eco +0.4 1.8 serine protease inhibitor ecotin compare
NOLOHH_21640 gfcB +0.4 1.1 Uncharacterized lipoprotein GfcB compare
NOLOHH_02190 +0.4 2.9 RHS repeat protein compare
NOLOHH_11090 dctQ +0.4 2.1 Tripartite ATP-independent periplasmic transporter, DctM component compare
NOLOHH_03090 sgrT +0.4 0.9 Putative inhibitor of glucose uptake transporter SgrT compare
NOLOHH_21275 solA +0.4 1.6 N-methyl-L-tryptophan oxidase compare
NOLOHH_01185 ybaY +0.4 1.4 Uncharacterized lipoprotein YbaY compare
NOLOHH_23295 mngR +0.4 1.4 mannosyl-D-glycerate transport/metabolism system transcriptional repressor MngR compare
NOLOHH_13510 hyfJ +0.4 1.8 hydrogenase 4 assembly chaperone HyfJ compare
NOLOHH_22270 +0.4 1.2 lipoprotein compare
NOLOHH_00825 purE +0.4 1.5 N5-carboxyaminoimidazole ribonucleotide mutase compare
NOLOHH_02070 gpt +0.4 1.7 xanthine phosphoribosyltransferase compare
NOLOHH_22975 +0.4 1.6 hypothetical protein compare
NOLOHH_12330 ecdD +0.4 1.0 Protein EcdD compare
NOLOHH_09305 arfA +0.4 1.2 alternative ribosome-rescue factor ArfA compare
NOLOHH_13595 vapB +0.4 1.1 toxin-antitoxin system antitoxin VapB compare
NOLOHH_16005 pduB +0.4 1.1 propanediol utilization microcompartment protein PduB compare
NOLOHH_09990 yhbQ +0.4 0.6 DNA damage response exodeoxyribonuclease YhbQ compare
NOLOHH_22735 moaA +0.4 1.6 GTP 3',8-cyclase MoaA compare
NOLOHH_16495 azuC +0.4 1.1 stress response protein AzuC compare
NOLOHH_09045 yhfA +0.4 0.9 OsmC family protein compare
NOLOHH_15020 fruA +0.4 2.2 PTS fructose transporter subunit IIBC compare
NOLOHH_12060 sdaC +0.4 1.1 HAAAP family serine/threonine permease SdaC compare
NOLOHH_16655 torZ +0.4 1.6 trimethylamine N-oxide reductase TorZ compare
NOLOHH_15250 yehQ +0.4 1.2 Protein YehQ compare
NOLOHH_21140 yceF +0.4 1.8 7-methyl-GTP pyrophosphatase compare
NOLOHH_15645 wcaA +0.4 1.7 colanic acid biosynthesis glycosyltransferase WcaA compare
NOLOHH_11920 +0.4 0.7 DUF2509 domain-containing protein compare
NOLOHH_02125 dinJ +0.4 1.1 type II toxin-antitoxin system antitoxin DinJ compare
NOLOHH_01465 brnQ +0.4 2.3 branched-chain amino acid transporter carrier protein BrnQ compare
NOLOHH_15500 yegQ +0.4 1.2 tRNA 5-hydroxyuridine modification protein YegQ compare
NOLOHH_23770 ybeF +0.4 1.9 YbeF family transcriptional regulator compare
NOLOHH_23075 ybhC +0.4 2.6 putative acyl-CoA thioester hydrolase compare
NOLOHH_12375 +0.4 1.3 hypothetical protein compare
NOLOHH_07725 yhhH +0.4 1.1 Uncharacterized protein YhhH compare
NOLOHH_16560 cheA +0.4 1.3 chemotaxis protein CheA compare
NOLOHH_22740 ybhK +0.4 1.7 Putative gluconeogenesis factor compare
NOLOHH_14975 mepS +0.4 2.2 bifunctional murein DD-endopeptidase/murein LD-carboxypeptidase compare
NOLOHH_11975 tcdA +0.4 1.9 tRNA cyclic N6-threonylcarbamoyladenosine(37) synthase TcdA compare
NOLOHH_06510 +0.4 0.9 Membrane protein compare
NOLOHH_23320 sdhB +0.4 0.9 succinate dehydrogenase iron-sulfur subunit SdhB compare
NOLOHH_11500 dsbC +0.4 2.5 bifunctional protein-disulfide isomerase/oxidoreductase DsbC compare
NOLOHH_22210 ybjX +0.4 1.5 Uncharacterized protein YbjX compare
NOLOHH_15415 +0.4 1.2 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase compare
NOLOHH_23730 rsfS +0.4 1.1 ribosome silencing factor compare
NOLOHH_00530 +0.4 0.7 Tail completion protein Z compare
NOLOHH_06100 yiiF +0.4 1.2 Uncharacterized protein YiiF compare
NOLOHH_15065 yeiH +0.4 1.3 UPF0324 membrane protein YeiH compare
NOLOHH_13790 yfeZ +0.4 1.0 Inner membrane protein YfeZ compare
NOLOHH_13930 xapR +0.4 0.9 DNA-binding transcriptional regulator XapR compare
NOLOHH_12690 ygaC +0.4 1.7 DUF2002 domain-containing protein compare
NOLOHH_19060 fdnG +0.4 1.4 formate dehydrogenase-N subunit alpha compare
NOLOHH_15375 +0.4 1.6 recombinase family protein compare
NOLOHH_23800 pagP +0.4 1.6 lipid IV(A) palmitoyltransferase PagP compare
NOLOHH_12350 otnK +0.4 1.8 3-oxo-tetronate kinase compare
NOLOHH_22550 rhtA +0.4 1.2 threonine/homoserine exporter RhtA compare
NOLOHH_04910 phnG +0.4 1.2 phosphonate C-P lyase system protein PhnG compare
NOLOHH_15930 pduT +0.4 1.0 propanediol utilization microcompartment protein PduT compare
NOLOHH_01325 +0.4 1.4 N-acetyltransferase compare
NOLOHH_02590 yaeH +0.4 1.2 DUF3461 domain-containing protein compare
NOLOHH_04230 ytfQ +0.4 2.0 galactofuranose ABC transporter substrate-binding protein YtfQ compare
NOLOHH_20660 dhaR +0.4 0.9 dihydroxyacetone kinase operon transcriptional regulator DhaR compare
NOLOHH_22660 lptB +0.4 1.9 LPS export ABC transporter ATP-binding protein compare
NOLOHH_23840 citX +0.4 1.2 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase compare
NOLOHH_20415 oppB +0.4 0.9 oligopeptide ABC transporter permease OppB compare
NOLOHH_14030 ypdE +0.4 1.3 aminopeptidase compare
NOLOHH_05480 zraP +0.4 1.7 zinc resistance sensor/chaperone ZraP compare
NOLOHH_15530 mdtD +0.4 1.7 Putative multidrug resistance protein MdtD compare
NOLOHH_16525 otsB +0.4 1.0 trehalose-phosphatase compare
NOLOHH_12620 emrA +0.4 1.7 multidrug efflux MFS transporter periplasmic adaptor subunit EmrA compare
NOLOHH_00275 +0.4 1.8 Conjugal transfer protein compare
NOLOHH_03955 nanS +0.4 2.0 putative 9-O-acetyl-N-acetylneuraminic acid deacetylase compare
NOLOHH_14405 yfcC +0.4 1.4 putative basic amino acid antiporter YfcC compare
NOLOHH_01920 ykgE +0.4 1.7 Uncharacterized protein YkgE compare
NOLOHH_22875 +0.4 0.9 Endolysin compare
NOLOHH_13615 ypfH +0.4 1.0 esterase compare
NOLOHH_05260 malM +0.4 2.0 maltose operon protein MalM compare


Specific Phenotypes

None in this experiment

For Escherichia coli ECOR27 in no phage control experiments

For no phage control No phage across organisms