Experiment set1IT053 for Serratia liquefaciens MT49

Compare to:

Nickel (II) chloride hexahydrate 80 uM, aerobic

200 most detrimental genes:

  gene name fitness t score description  
IAI46_24465 +1.7 7.5 HTH-type transcriptional repressor FabR compare
IAI46_18590 +0.9 3.7 hypothetical protein compare
IAI46_16365 +0.9 2.5 phenylacetate-CoA oxygenase subunit PaaJ compare
IAI46_18550 +0.9 1.9 YaiI/YqxD family protein compare
IAI46_19345 +0.8 2.3 iron-sulfur cluster assembly protein IscA compare
IAI46_16460 +0.8 1.9 glycogen synthesis protein compare
IAI46_14385 +0.8 2.1 GNAT family N-acetyltransferase compare
IAI46_10940 +0.8 2.0 CAP-Gly protein compare
IAI46_11185 +0.8 2.5 pyruvate kinase PykF compare
IAI46_19820 +0.7 2.4 N-acetyltransferase compare
IAI46_07875 +0.7 1.0 hypothetical protein compare
IAI46_14560 +0.7 1.8 multidrug/spermidine efflux SMR transporter subunit MdtI compare
IAI46_15395 +0.7 2.6 ABC transporter permease compare
IAI46_11580 +0.7 2.2 DeoR/GlpR transcriptional regulator compare
IAI46_12310 +0.7 2.0 alcohol dehydrogenase AdhP compare
IAI46_10385 +0.7 2.8 cupin domain-containing protein compare
IAI46_08930 +0.7 2.4 acyltransferase family protein compare
IAI46_04045 +0.7 2.8 acyl carrier protein compare
IAI46_09885 +0.7 2.2 YcfL family protein compare
IAI46_06565 +0.6 2.6 GTP 3',8-cyclase MoaA compare
IAI46_19080 +0.6 1.8 DNA-binding transcriptional repressor compare
IAI46_11875 +0.6 1.3 DUF1003 domain-containing protein compare
IAI46_17665 +0.6 0.9 NADH-quinone oxidoreductase subunit NuoK compare
IAI46_10680 +0.6 2.0 DUF917 domain-containing protein compare
IAI46_19765 +0.6 1.6 hypothetical protein compare
IAI46_15115 +0.6 2.4 hypothetical protein compare
IAI46_20515 +0.6 2.0 helix-turn-helix transcriptional regulator compare
IAI46_08350 +0.6 2.0 glutaredoxin, GrxA family compare
IAI46_11380 +0.6 2.0 pyridoxal kinase PdxY compare
IAI46_14400 +0.6 1.8 YqaE/Pmp3 family membrane protein compare
IAI46_17735 +0.6 1.5 sugar phosphatase compare
IAI46_15100 +0.6 1.8 hypothetical protein compare
IAI46_05590 +0.6 1.5 DotU family type IV/VI secretion system protein compare
IAI46_00620 +0.6 2.9 dTDP-4-amino-4,6-dideoxy-D-galactose acyltransferase compare
IAI46_24255 +0.6 4.6 response regulator compare
IAI46_13885 +0.6 2.0 glycyl-radical enzyme activating protein compare
IAI46_07500 +0.6 2.1 DUF1471 domain-containing protein compare
IAI46_23265 +0.6 1.0 peptide deformylase compare
IAI46_04970 +0.5 2.1 cytochrome o ubiquinol oxidase subunit IV compare
IAI46_16060 +0.5 1.7 flagellar transcriptional regulator FlhD compare
IAI46_08960 +0.5 1.3 hypothetical protein compare
IAI46_04425 +0.5 1.7 sigma factor-binding protein Crl compare
IAI46_15250 +0.5 1.5 hypothetical protein compare
IAI46_14890 +0.5 1.9 PhoP/PhoQ regulator MgrB compare
IAI46_16990 +0.5 1.8 citrate lyase subunit alpha compare
IAI46_11465 +0.5 1.7 electron transport complex subunit RsxG compare
IAI46_05350 +0.5 1.2 ABC transporter ATP-binding protein compare
IAI46_06610 +0.5 2.1 secretion protein HlyD compare
IAI46_06110 +0.5 2.8 hypothetical protein compare
IAI46_04980 +0.5 4.3 cytochrome o ubiquinol oxidase subunit I compare
IAI46_19690 +0.5 2.9 AlpA family transcriptional regulator compare
IAI46_15895 +0.5 2.0 flagellar biosynthesis protein FliQ compare
IAI46_11295 +0.5 1.3 NAD(P)-dependent oxidoreductase compare
IAI46_09460 +0.5 0.9 phenylalanyl-tRNA synthetase subunit beta compare
IAI46_12725 +0.5 1.2 TetR/AcrR family transcriptional regulator compare
IAI46_13970 +0.5 0.9 type I DNA topoisomerase compare
IAI46_12940 +0.5 2.0 carbohydrate ABC transporter permease compare
IAI46_17885 +0.5 1.8 tripartite tricarboxylate transporter TctB family protein compare
IAI46_20790 +0.5 2.7 hypothetical protein compare
IAI46_16835 +0.5 1.3 DUF2623 family protein compare
IAI46_18865 +0.5 1.0 E3 ubiquitin--protein ligase compare
IAI46_07545 +0.5 2.2 DNA starvation/stationary phase protection protein Dps compare
IAI46_15965 +0.5 1.7 flagellar basal body P-ring formation protein FlgA compare
IAI46_05745 +0.5 1.1 gamma-glutamylcyclotransferase compare
IAI46_15105 +0.5 2.0 phage holin, lambda family compare
IAI46_10760 +0.5 1.3 spore coat protein U domain-containing protein compare
IAI46_15180 +0.5 2.9 replication protein compare
IAI46_10995 +0.5 1.4 DUF2502 domain-containing protein compare
IAI46_14870 +0.5 1.4 DUF4060 family protein compare
IAI46_00570 +0.5 2.7 exopolyphosphatase compare
IAI46_01910 +0.5 1.1 preprotein translocase subunit SecG compare
IAI46_14655 +0.5 1.8 hydrolase compare
IAI46_03890 +0.5 2.0 DedA family protein compare
IAI46_10625 +0.5 1.3 HutD family protein compare
IAI46_12195 +0.5 1.2 CopG family transcriptional regulator compare
IAI46_21470 +0.5 1.8 oxidative damage protection protein compare
IAI46_10010 +0.5 1.8 copper homeostasis membrane protein CopD compare
IAI46_12845 +0.5 2.0 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase compare
IAI46_05705 +0.5 1.2 hypothetical protein compare
IAI46_10165 +0.5 1.7 universal stress protein compare
IAI46_15955 +0.5 2.1 flagellar basal body rod protein FlgC compare
IAI46_14615 +0.5 1.3 zinc ABC transporter permease subunit ZnuB compare
IAI46_22855 +0.5 1.3 DUF1471 domain-containing protein compare
IAI46_04860 +0.4 1.5 response regulator transcription factor compare
IAI46_19990 +0.4 1.9 transcriptional repressor MprA compare
IAI46_06680 +0.4 2.1 fimbria/pilus periplasmic chaperone compare
IAI46_12110 +0.4 1.5 beta-lactamase family protein compare
IAI46_12560 +0.4 1.1 hydrogenase formation protein HypD compare
IAI46_17300 +0.4 2.7 phosphatase PAP2 family protein compare
IAI46_08540 +0.4 1.7 glutathione transferase GstA compare
IAI46_09360 +0.4 1.4 Pyocin large subunit compare
IAI46_09990 +0.4 1.6 prolyl aminopeptidase compare
IAI46_15260 +0.4 2.4 hypothetical protein compare
IAI46_18870 +0.4 1.9 GlsB/YeaQ/YmgE family stress response membrane protein compare
IAI46_07015 +0.4 1.5 LysE family translocator compare
IAI46_14600 +0.4 2.7 murein DD-endopeptidase MepM compare
IAI46_13290 +0.4 2.1 hypothetical protein compare
IAI46_18720 +0.4 2.2 GNAT family N-acetyltransferase compare
IAI46_19735 +0.4 1.4 histidine kinase compare
IAI46_09075 +0.4 1.4 hypothetical protein compare
IAI46_04775 +0.4 2.7 phosphate response regulator transcription factor PhoB compare
IAI46_03305 +0.4 1.2 thiamine ABC transporter ATP-binding protein ThiQ compare
IAI46_13030 +0.4 1.8 elongation factor G compare
IAI46_12000 +0.4 1.5 multidrug efflux MFS transporter compare
IAI46_18900 +0.4 1.7 phosphate ABC transporter ATP-binding protein compare
IAI46_22770 +0.4 1.5 50S ribosomal protein L11 methyltransferase compare
IAI46_18615 +0.4 2.5 LysR family transcriptional regulator compare
IAI46_20735 +0.4 2.1 flavodoxin FldB compare
IAI46_21620 +0.4 1.4 hypothetical protein compare
IAI46_12015 +0.4 1.0 MurR/RpiR family transcriptional regulator compare
IAI46_13140 +0.4 2.0 polyphosphate kinase 2 compare
IAI46_16170 +0.4 1.3 3-oxoadipate enol-lactonase compare
IAI46_00625 +0.4 2.6 dTDP-4-amino-4,6-dideoxygalactose transaminase compare
IAI46_09160 +0.4 2.2 4-hydroxyproline epimerase compare
IAI46_11470 +0.4 1.8 electron transport complex subunit RsxD compare
IAI46_19335 +0.4 2.1 Fe-S protein assembly chaperone HscA compare
IAI46_15005 +0.4 1.4 hypothetical protein compare
IAI46_17415 +0.4 0.6 nuclear transport factor 2 family protein compare
IAI46_15020 +0.4 1.8 hypothetical protein compare
IAI46_11765 +0.4 1.3 sugar ABC transporter permease compare
IAI46_13025 +0.4 1.0 ABC transporter ATP-binding protein compare
IAI46_20035 +0.4 1.1 YfiM family lipoprotein compare
IAI46_09255 +0.4 2.3 6-phospho-beta-glucosidase compare
IAI46_14015 +0.4 1.2 PHP domain-containing protein compare
IAI46_07805 +0.4 2.2 carbonic anhydrase compare
IAI46_06150 +0.4 0.5 helix-turn-helix transcriptional regulator compare
IAI46_21175 +0.4 2.2 Fe(3+)-hydroxamate ABC transporter substrate-binding protein FhuD compare
IAI46_06290 +0.4 1.3 succinate--CoA ligase subunit alpha compare
IAI46_08400 +0.4 1.6 arginine ABC transporter substrate-binding protein compare
IAI46_20960 +0.4 2.8 MFS transporter compare
IAI46_10655 +0.4 1.1 hydrolase compare
IAI46_09425 +0.4 1.0 hypothetical protein compare
IAI46_11320 +0.4 1.4 superoxide dismutase family protein compare
IAI46_06170 +0.4 1.5 potassium-transporting ATPase subunit KdpC compare
IAI46_21155 +0.4 2.2 Hok/Gef family protein compare
IAI46_19615 +0.4 1.6 autonomous glycyl radical cofactor GrcA compare
IAI46_20425 +0.4 2.6 YgdB family protein compare
IAI46_00895 +0.4 2.3 hypothetical protein compare
IAI46_11485 +0.4 1.2 electron transport complex subunit RsxB compare
IAI46_04395 +0.4 2.3 (Na+)-NQR maturation NqrM compare
IAI46_06130 +0.4 1.6 LexA regulated protein compare
IAI46_11715 +0.4 1.5 YnfA family protein compare
IAI46_11055 +0.4 0.9 lipoate--protein ligase A compare
IAI46_14260 +0.4 2.1 YchJ family protein compare
IAI46_14860 +0.4 1.4 hypothetical protein compare
IAI46_04710 +0.4 2.1 recombination-associated protein RdgC compare
IAI46_23760 +0.4 1.8 ribosome-associated heat shock protein Hsp15 compare
IAI46_11420 +0.4 1.3 RidA family protein compare
IAI46_15285 +0.4 1.3 DUF5405 family protein compare
IAI46_09320 +0.4 1.0 AlpA family phage regulatory protein compare
IAI46_05210 +0.4 1.0 pleiotropic regulatory protein RsmS compare
IAI46_19375 +0.4 1.7 nickel/cobalt transporter compare
IAI46_05695 +0.4 1.8 toxin compare
IAI46_17555 +0.4 1.7 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase compare
IAI46_12785 +0.4 1.5 MFS transporter compare
IAI46_11795 +0.4 0.6 xanthine dehydrogenase accessory protein XdhC compare
IAI46_12655 +0.4 1.1 LysR family transcriptional regulator compare
IAI46_11220 +0.4 1.0 peptidase inhibitor I78 family protein compare
IAI46_11305 +0.4 0.4 DUF1289 domain-containing protein compare
IAI46_11510 +0.4 1.2 arabinose ABC transporter substrate-binding protein compare
IAI46_03790 +0.4 2.6 RNA polymerase sigma factor RpoS compare
IAI46_12670 +0.4 1.1 MarR family transcriptional regulator compare
IAI46_24895 +0.4 0.9 bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase compare
IAI46_10190 +0.4 0.7 beta-galactosidase subunit beta compare
IAI46_11680 +0.4 1.0 LysR family transcriptional regulator compare
IAI46_21240 +0.4 1.6 3-methyl-2-oxobutanoate hydroxymethyltransferase compare
IAI46_21450 +0.4 2.4 glutaminase B compare
IAI46_23140 +0.4 1.7 alkaline phosphatase family protein compare
IAI46_10235 +0.4 1.7 dihydrofolate reductase compare
IAI46_09565 +0.4 1.6 hypothetical protein compare
IAI46_23950 +0.4 0.9 YhgN family NAAT transporter compare
IAI46_06515 +0.4 1.3 DUF1232 domain-containing protein compare
IAI46_10115 +0.4 1.0 FadR family transcriptional regulator compare
IAI46_05545 +0.4 0.6 hypothetical protein compare
IAI46_14980 +0.4 1.7 oxidoreductase compare
IAI46_20495 +0.4 2.0 HTH-type transcriptional regulator GalR compare
IAI46_24245 +0.4 2.2 molybdopterin-dependent oxidoreductase compare
IAI46_04255 +0.4 2.1 amino acid ABC transporter permease compare
IAI46_11475 +0.4 1.1 helix-turn-helix domain-containing protein compare
IAI46_13055 +0.4 1.1 alpha/beta hydrolase compare
IAI46_09045 +0.4 0.8 pyrimidine utilization protein B compare
IAI46_15095 +0.4 1.3 lysozyme compare
IAI46_17490 +0.4 2.0 SDR family oxidoreductase compare
IAI46_04805 +0.4 0.7 hypothetical protein compare
IAI46_03175 +0.3 2.6 2-dehydro-3-deoxygalactonokinase compare
IAI46_13910 +0.3 1.0 stress response translation initiation inhibitor YciH compare
IAI46_02675 +0.3 2.2 alpha/beta hydrolase compare
IAI46_01280 +0.3 2.5 HAMP domain-containing histidine kinase compare
IAI46_04220 +0.3 1.6 ribbon-helix-helix protein, CopG family compare
IAI46_03895 +0.3 1.8 glutamate--cysteine ligase compare
IAI46_11920 +0.3 1.0 chromate transporter compare
IAI46_07880 +0.3 1.9 S-formylglutathione hydrolase compare
IAI46_03605 +0.3 2.6 nucleoside triphosphate pyrophosphohydrolase compare
IAI46_04215 +0.3 1.0 type II toxin-antitoxin system RelE/ParE family toxin compare
IAI46_01780 +0.3 1.9 gamma-glutamylcyclotransferase compare
IAI46_03340 +0.3 0.5 3-isopropylmalate dehydratase small subunit compare
IAI46_09715 +0.3 1.5 helix-turn-helix transcriptional regulator compare
IAI46_10390 +0.3 1.9 two-component system sensor histidine kinase PhoQ compare
IAI46_16750 +0.3 1.4 heavy metal sensor histidine kinase compare
IAI46_08510 +0.3 2.0 ATP-dependent Clp protease adapter ClpS compare


Specific Phenotypes

None in this experiment

For Serratia liquefaciens MT49 in stress experiments

For stress Nickel (II) chloride hexahydrate across organisms