Experiment set1IT045 for Echinicola vietnamensis KMM 6221, DSM 17526

Compare to:

marine broth with Polymyxin B sulfate 1 mg/ml

200 most detrimental genes:

  gene name fitness t score description  
Echvi_0776 +2.5 20.4 Sterol desaturase compare
Echvi_0363 +2.4 19.2 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 compare
Echvi_2047 +2.4 14.4 RNA polymerase sigma factor, sigma-70 family compare
Echvi_2783 +2.2 15.1 signal peptide peptidase SppA, 67K type compare
Echvi_2188 +2.1 15.6 Methyltransferase domain. compare
Echvi_1060 +2.1 17.2 Methyltransferase domain. compare
Echvi_3576 +2.1 19.4 Subtilisin-like serine proteases compare
Echvi_0882 +2.0 15.1 Mismatch repair ATPase (MutS family) compare
Echvi_2637 +2.0 17.4 Predicted esterase of the alpha-beta hydrolase superfamily compare
Echvi_0830 +1.8 15.6 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family compare
Echvi_3918 +1.8 3.8 Histone H1-like protein Hc1. compare
Echvi_3370 +1.8 4.5 Predicted membrane protein compare
Echvi_0045 +1.8 12.1 Protein of unknown function (DUF3108). compare
Echvi_3859 +1.7 10.4 Glycosyltransferases, probably involved in cell wall biogenesis compare
Echvi_4618 +1.7 4.7 Methylase involved in ubiquinone/menaquinone biosynthesis compare
Echvi_0724 +1.7 5.2 hypothetical protein compare
Echvi_1610 +1.7 15.3 Zinc carboxypeptidase. compare
Echvi_4639 +1.7 15.6 TonB-linked outer membrane protein, SusC/RagA family compare
Echvi_1131 +1.7 6.1 hypothetical protein compare
Echvi_3110 +1.7 6.5 ABC-type hemin transport system, periplasmic component compare
Echvi_4638 +1.6 14.6 SusD family. compare
Echvi_0745 +1.6 13.6 Predicted aminopeptidases compare
Echvi_2904 +1.6 3.9 Protein of unknown function (DUF3302). compare
Echvi_1917 +1.5 5.1 hypothetical protein compare
Echvi_1146 +1.5 10.0 Predicted membrane protein compare
Echvi_2309 +1.4 12.5 Outer membrane protein/protective antigen OMA87 compare
Echvi_4404 +1.4 11.6 nucleotide sugar dehydrogenase compare
Echvi_0750 +1.4 3.7 hypothetical protein compare
Echvi_0852 +1.4 12.4 Parvulin-like peptidyl-prolyl isomerase compare
Echvi_1170 +1.4 2.9 Predicted membrane protein compare
Echvi_4631 +1.3 9.0 (p)ppGpp synthetase, RelA/SpoT family compare
Echvi_3640 +1.3 10.4 hypothetical protein compare
Echvi_2984 +1.3 5.8 hypothetical protein compare
Echvi_3379 +1.3 11.3 hypothetical protein compare
Echvi_4422 +1.3 9.4 Aminopeptidase N compare
Echvi_4074 +1.2 5.7 Tetratricopeptide repeat. compare
Echvi_3378 +1.2 3.4 Rhodanese-related sulfurtransferase compare
Echvi_4100 +1.2 4.1 hypothetical protein compare
Echvi_1948 +1.2 1.9 hypothetical protein compare
Echvi_0333 +1.2 11.1 Bacteroidetes-specific putative membrane protein compare
Echvi_3369 +1.2 5.2 Protein of unknown function (DUF2752). compare
Echvi_0733 +1.2 10.2 Outer membrane protein and related peptidoglycan-associated (lipo)proteins compare
Echvi_1949 +1.2 3.5 hypothetical protein compare
Echvi_0058 +1.2 7.8 Protein of unknown function (DUF3078). compare
Echvi_0038 +1.2 4.8 Putative regulator of cell autolysis compare
Echvi_3037 +1.1 6.3 Putative regulator of cell autolysis compare
Echvi_2317 +1.1 1.3 pyruvate kinase compare
Echvi_2829 +1.1 10.7 hypothetical protein compare
Echvi_0334 +1.1 10.7 hypothetical protein compare
Echvi_1758 +1.1 4.5 Gas vesicle protein compare
Echvi_3716 +1.1 2.1 rRNA methylases compare
Echvi_2793 +1.1 10.3 hypothetical protein compare
Echvi_0624 +1.1 9.0 Bacteroidetes-specific putative membrane protein compare
Echvi_1947 +1.1 4.8 Bacteroides conjugation system ATPase, TraG family compare
Echvi_1334 +1.1 6.6 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II compare
Echvi_1888 +1.1 9.3 hypothetical protein compare
Echvi_1206 +1.0 6.0 TIGR00730 family protein compare
Echvi_4582 +1.0 1.9 Outer membrane protein and related peptidoglycan-associated (lipo)proteins compare
Echvi_3451 +1.0 2.5 hypothetical protein compare
Echvi_0642 +1.0 4.4 pseudouridine synthase, RluA family compare
Echvi_0484 +1.0 1.8 hypothetical protein compare
Echvi_0903 +1.0 6.5 Glycosyltransferases involved in cell wall biogenesis compare
Echvi_2455 +1.0 2.6 hypothetical protein compare
Echvi_3371 +1.0 5.8 hypothetical protein compare
Echvi_2554 +0.9 1.5 hypothetical protein compare
Echvi_0206 +0.9 6.8 Transcriptional regulators of sugar metabolism compare
Echvi_2004 +0.9 3.5 Predicted transcriptional regulator compare
Echvi_0199 +0.9 6.5 hypothetical protein compare
Echvi_0897 +0.9 1.8 hypothetical protein compare
Echvi_0603 +0.9 5.1 RNA polymerase sigma factor, sigma-70 family compare
Echvi_3112 +0.9 2.6 ABC-type hemin transport system, ATPase component compare
Echvi_1108 +0.9 7.1 hypothetical protein compare
Echvi_3824 +0.9 2.4 hypothetical protein compare
Echvi_1298 +0.9 5.8 hypothetical protein compare
Echvi_3764 +0.8 2.2 Predicted transcriptional regulators compare
Echvi_4405 +0.8 3.2 hypothetical protein compare
Echvi_4232 +0.8 2.3 Glycosyltransferase compare
Echvi_0904 +0.8 6.4 conserved hypothetical protein compare
Echvi_4403 +0.8 4.6 Predicted endonuclease containing a URI domain compare
Echvi_4401 +0.8 5.8 Uncharacterized protein involved in exopolysaccharide biosynthesis compare
Echvi_2897 +0.8 7.1 TonB-linked outer membrane protein, SusC/RagA family compare
Echvi_2075 +0.8 4.9 Cyclic nucleotide-binding domain. compare
Echvi_0732 +0.8 1.6 hypothetical protein compare
Echvi_2258 +0.8 1.9 hypothetical protein compare
Echvi_2898 +0.8 5.8 hypothetical protein compare
Echvi_4229 +0.8 3.8 Uncharacterized conserved protein compare
Echvi_4674 +0.8 2.0 Nucleotidyltransferase substrate binding protein like. compare
Echvi_2428 +0.8 1.2 iojap-like ribosome-associated protein compare
Echvi_0584 +0.8 4.3 peptide chain release factor 3 compare
Echvi_1980 +0.8 2.0 hypothetical protein compare
Echvi_3358 +0.8 1.4 hypothetical protein compare
Echvi_0985 +0.8 4.5 Predicted membrane protein compare
Echvi_0711 +0.7 2.1 hypothetical protein compare
Echvi_0012 +0.7 4.1 ABC-type antimicrobial peptide transport system, ATPase component compare
Echvi_1979 +0.7 1.9 Bacterial mobilisation protein (MobC). compare
Echvi_3858 +0.7 3.7 Methyltransferase domain. compare
Echvi_2184 +0.7 2.8 hypothetical protein compare
Echvi_3361 +0.7 2.9 Predicted esterase of the alpha-beta hydrolase superfamily compare
Echvi_1978 +0.7 4.3 Relaxase/Mobilisation nuclease domain. compare
Echvi_1742 +0.7 1.2 Uncharacterized protein conserved in archaea compare
Echvi_1297 +0.7 2.7 hypothetical protein compare
Echvi_1295 +0.7 6.0 diaminopimelate decarboxylase (EC 4.1.1.20) (from data) compare
Echvi_1477 +0.7 5.1 phytoene desaturase compare
Echvi_2505 +0.7 2.1 S23 ribosomal protein. compare
Echvi_1294 +0.7 3.3 hypothetical protein compare
Echvi_2334 +0.7 2.6 Uncharacterized conserved protein compare
Echvi_0083 +0.7 3.5 Predicted xylanase/chitin deacetylase compare
Echvi_0128 +0.7 1.3 hypothetical protein compare
Echvi_1800 +0.7 3.5 sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family compare
Echvi_0616 +0.7 4.2 Membrane proteins related to metalloendopeptidases compare
Echvi_0980 +0.7 3.9 uroporphyrin-III C-methyltransferase compare
Echvi_2036 +0.7 3.6 Predicted xylanase/chitin deacetylase compare
Echvi_3753 +0.7 2.1 hypothetical protein compare
Echvi_4308 +0.7 1.0 hypothetical protein compare
Echvi_0630 +0.7 6.0 hypothetical protein compare
Echvi_2298 +0.7 1.0 hypothetical protein compare
Echvi_3813 +0.7 1.7 Uncharacterized protein conserved in bacteria compare
Echvi_1160 +0.7 5.3 Alpha-L-fucosidase compare
Echvi_1998 +0.7 2.0 Heat shock protein compare
Echvi_1849 +0.6 4.5 Sugar phosphate isomerases/epimerases compare
Echvi_1592 +0.6 2.0 Cytosine/adenosine deaminases compare
Echvi_1765 +0.6 1.1 Cell wall-associated hydrolases (invasion-associated proteins) compare
Echvi_3442 +0.6 2.7 Putative transcriptional regulator compare
Echvi_3680 +0.6 2.1 Predicted transcriptional regulators compare
Echvi_2832 +0.6 2.4 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase compare
Echvi_0751 +0.6 4.0 glycogen debranching enzyme, archaeal type, putative compare
Echvi_4231 +0.6 3.5 Glycosyltransferases involved in cell wall biogenesis compare
Echvi_4058 +0.6 2.6 PspC domain. compare
Echvi_1180 +0.6 1.6 non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family compare
Echvi_4099 +0.6 1.4 hypothetical protein compare
Echvi_2205 +0.6 5.3 hypothetical protein compare
Echvi_4230 +0.6 3.8 Membrane protein involved in the export of O-antigen and teichoic acid compare
Echvi_2079 +0.6 1.6 Uncharacterized conserved protein compare
Echvi_0048 +0.6 1.5 Pseudouridylate synthases, 23S RNA-specific compare
Echvi_4102 +0.6 3.3 Relaxase/Mobilisation nuclease domain. compare
Echvi_0727 +0.6 0.7 hypothetical protein compare
Echvi_0845 +0.6 2.3 hypothetical protein compare
Echvi_1563 +0.6 1.2 Uncharacterized homolog of Blt101 compare
Echvi_4402 +0.6 4.4 Periplasmic protein involved in polysaccharide export compare
Echvi_0039 +0.6 2.1 Predicted membrane protein (DUF2154). compare
Echvi_1732 +0.6 0.8 hypothetical protein compare
Echvi_4416 +0.6 2.8 hypothetical protein compare
Echvi_2526 +0.6 3.6 Predicted permease compare
Echvi_1728 +0.6 1.3 pseudouridylate synthase I compare
Echvi_0582 +0.6 2.4 hypothetical protein compare
Echvi_1544 +0.6 2.2 META domain. compare
Echvi_2339 +0.6 1.9 Cytochrome bd-type quinol oxidase, subunit 1 compare
Echvi_3040 +0.6 3.8 Membrane proteins related to metalloendopeptidases compare
Echvi_1893 +0.6 1.8 molybdenum cofactor biosynthesis protein MoaC compare
Echvi_1318 +0.6 3.9 Secreted and surface protein containing fasciclin-like repeats compare
Echvi_0395 +0.6 1.2 DNA repair proteins compare
Echvi_2385 +0.6 1.0 hypothetical protein compare
Echvi_1492 +0.6 1.1 hypothetical protein compare
Echvi_0011 +0.6 3.4 ABC-type transport system, involved in lipoprotein release, permease component compare
Echvi_1259 +0.6 1.4 methionine-R-sulfoxide reductase compare
Echvi_2321 +0.6 1.7 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Echvi_4510 +0.5 2.0 Cystathionine beta-lyases/cystathionine gamma-synthases compare
Echvi_2221 +0.5 2.1 Protein of unknown function (DUF1573). compare
Echvi_4233 +0.5 3.5 Glycosyltransferase compare
Echvi_2998 +0.5 1.7 hypothetical protein compare
Echvi_4362 +0.5 1.5 hypothetical protein compare
Echvi_2199 +0.5 0.9 hypothetical protein compare
Echvi_1588 +0.5 2.3 deoxyribose-phosphate aldolase compare
Echvi_1611 +0.5 1.9 hypothetical protein compare
Echvi_2363 +0.5 2.6 Predicted ring-cleavage extradiol dioxygenase compare
Echvi_1362 +0.5 3.7 Bacteroides conjugation system ATPase, TraG family compare
Echvi_2238 +0.5 1.7 hypothetical protein compare
Echvi_4371 +0.5 2.0 hypothetical protein compare
Echvi_4585 +0.5 2.6 Mg-chelatase subunit ChlD compare
Echvi_2680 +0.5 1.3 hypothetical protein compare
Echvi_0524 +0.5 4.5 hypothetical protein compare
Echvi_3223 +0.5 1.9 Mn-dependent transcriptional regulator compare
Echvi_2185 +0.5 1.9 Protein of unknown function (DUF2874). compare
Echvi_2001 +0.5 2.9 homoserine kinase (EC 2.7.1.39) (from data) compare
Echvi_0660 +0.5 1.8 Uncharacterized conserved protein compare
Echvi_0120 +0.5 2.6 2-keto-3-deoxy-D-arabino-heptulosonate-7-phosphate synthase / chorismate mutase (EC 2.5.1.54; EC 5.4.99.5) (from data) compare
Echvi_1366 +0.5 1.9 hypothetical protein compare
Echvi_0391 +0.5 2.0 Bacterial mobilisation protein (MobC). compare
Echvi_2934 +0.5 3.6 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain compare
Echvi_3075 +0.5 1.1 hypothetical protein compare
Echvi_4420 +0.5 2.0 hypothetical protein compare
Echvi_0817 +0.5 1.9 hypothetical protein compare
Echvi_0717 +0.5 1.4 DnaK suppressor protein compare
Echvi_4361 +0.5 1.4 hypothetical protein compare
Echvi_1578 +0.5 2.6 hypothetical protein compare
Echvi_4465 +0.5 1.5 hypothetical protein compare
Echvi_1022 +0.5 3.3 ABC-type spermidine/putrescine transport systems, ATPase components compare
Echvi_2937 +0.5 0.8 Uncharacterized conserved protein compare
Echvi_3193 +0.5 0.8 hypothetical protein compare
Echvi_3919 +0.5 3.3 Domain of Unknown Function (DUF1080). compare
Echvi_0113 +0.5 2.9 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) compare
Echvi_3164 +0.5 2.2 hypothetical protein compare
Echvi_0679 +0.5 3.3 hypothetical protein compare
Echvi_0357 +0.5 2.0 hypothetical protein compare
Echvi_0086 +0.5 3.3 Glycosyltransferases, probably involved in cell wall biogenesis compare
Echvi_0347 +0.5 2.3 Phosphate starvation-inducible protein PhoH, predicted ATPase compare
Echvi_0390 +0.5 2.8 Relaxase/Mobilisation nuclease domain. compare
Echvi_3111 +0.5 2.6 ABC-type Fe3+-siderophore transport system, permease component compare
Echvi_2088 +0.5 2.1 Restriction endonuclease compare
Echvi_1997 +0.5 1.8 hypothetical protein compare


Specific Phenotypes

For 50 genes in this experiment

For stress Polymyxin B sulfate in Echinicola vietnamensis KMM 6221, DSM 17526

For stress Polymyxin B sulfate across organisms