Experiment set1IT043 for Pseudomonas fluorescens GW456-L13

Compare to:

LB with Zinc sulfate heptahydrate 1 mM

200 most detrimental genes:

  gene name fitness t score description  
PfGW456L13_1391 +1.2 3.3 Transcriptional regulator, AsnC family compare
PfGW456L13_1637 +1.1 5.5 Stringent starvation protein A compare
PfGW456L13_3260 +1.1 2.3 hypothetical protein compare
PfGW456L13_5008 +1.0 2.4 Uncharacterized ABC transporter, ATP-binding protein YrbF compare
PfGW456L13_4026 +1.0 1.8 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
PfGW456L13_62 +0.9 1.9 hypothetical protein compare
PfGW456L13_3990 +0.9 3.8 Response regulator receiver domain protein (CheY) compare
PfGW456L13_5003 +0.9 1.7 YrbA protein compare
PfGW456L13_4243 +0.9 2.3 Cob(I)alamin adenosyltransferase (EC 2.5.1.17) compare
PfGW456L13_1848 +0.9 1.1 hypothetical protein compare
PfGW456L13_4013 +0.8 2.9 Phosphonoacetaldehyde phosphonohydrolase-related protein compare
PfGW456L13_2695 +0.8 1.8 hypothetical protein compare
PfGW456L13_4642 +0.8 2.5 Cold shock protein CspA compare
PfGW456L13_2931 +0.8 1.4 transcriptional regulator MvaT, P16 subunit, putative compare
PfGW456L13_5096 +0.8 1.7 FIG004454: RNA binding protein compare
PfGW456L13_4781 +0.8 2.4 Nudix hydrolase family protein PA3470 compare
PfGW456L13_4036 +0.8 1.8 FIG00954079: hypothetical protein compare
PfGW456L13_1883 +0.7 3.4 Heme oxygenase HemO, associated with heme uptake compare
PfGW456L13_4742 +0.7 2.6 FIG00953405: hypothetical protein compare
PfGW456L13_2797 +0.7 2.7 hypothetical protein compare
PfGW456L13_2968 +0.7 3.3 hypothetical protein compare
PfGW456L13_5059 +0.7 1.2 hypothetical protein compare
PfGW456L13_2946 +0.7 1.5 Aspartate aminotransferase (EC 2.6.1.1) compare
PfGW456L13_3964 +0.7 1.8 Asl2195 protein compare
PfGW456L13_4701 +0.7 4.4 Membrane-associated zinc metalloprotease compare
PfGW456L13_4932 +0.7 4.7 Heme O synthase, protoheme IX farnesyltransferase (EC 2.5.1.-) COX10-CtaB compare
PfGW456L13_1954 +0.7 1.4 hypothetical protein compare
PfGW456L13_1537 +0.7 2.5 Hypothetical protein YqcC (clustered with tRNA pseudouridine synthase C) compare
PfGW456L13_3300 +0.6 4.6 MoxR-like ATPase in aerotolerance operon compare
PfGW456L13_1838 +0.6 2.7 Sensory box histidine kinase compare
PfGW456L13_3683 +0.6 2.5 FIG00957787: hypothetical protein compare
PfGW456L13_234 +0.6 1.8 3-oxoacyl-[ACP] synthase compare
PfGW456L13_4883 +0.6 2.5 S-adenosylmethionine:tRNA ribosyltransferase-isomerase (EC 5.-.-.-) compare
PfGW456L13_4955 +0.6 1.2 FIG00954638: hypothetical protein compare
PfGW456L13_3846 +0.6 1.9 Predicted secretion system X FIG084745: hypothetical protein compare
PfGW456L13_1022 +0.6 2.0 twitching motility protein PilG compare
PfGW456L13_3709 +0.6 1.4 Cation efflux system protein CusF precursor compare
PfGW456L13_2889 +0.6 1.5 hypothetical protein compare
PfGW456L13_1997 +0.6 2.9 Negative regulator of flagellin synthesis FlgM compare
PfGW456L13_4051 +0.6 1.5 LSU rRNA 2'-O-methyl-C2498 methyltransferase RlmM compare
PfGW456L13_4831 +0.6 2.6 Glucosamine-6-phosphate deaminase [isomerizing], alternative (EC 3.5.99.6) (from data) compare
PfGW456L13_1886 +0.6 2.4 FIG006045: Sigma factor, ECF subfamily compare
PfGW456L13_249 +0.6 2.0 FIG085779: Lipoprotein compare
PfGW456L13_2987 +0.6 2.3 Transcriptional regulator compare
PfGW456L13_4125 +0.6 1.9 Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10) compare
PfGW456L13_2435 +0.6 2.4 Phenylacetic acid degradation protein PaaY compare
PfGW456L13_1050 +0.6 3.8 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
PfGW456L13_1749 +0.6 2.6 Argininosuccinate synthase (EC 6.3.4.5) compare
PfGW456L13_4171 +0.6 0.8 FIG00956876: hypothetical protein compare
PfGW456L13_1421 +0.6 2.1 Sugar phosphate isomerases/epimerases compare
PfGW456L13_1829 +0.6 1.7 glycosyl transferase, group 1 family protein compare
PfGW456L13_2314 +0.5 1.8 ABC-type proline/glycine betaine transport systems, ATPase components compare
PfGW456L13_4466 +0.5 2.5 hypothetical protein compare
PfGW456L13_4154 +0.5 1.8 FIG00957412: hypothetical protein compare
PfGW456L13_1985 +0.5 2.2 Alginate biosynthesis transcriptional activator compare
PfGW456L13_3303 +0.5 3.3 BatA (Bacteroides aerotolerance operon) compare
PfGW456L13_4255 +0.5 2.4 FIG00964480: hypothetical protein compare
PfGW456L13_766 +0.5 0.8 hypothetical protein compare
PfGW456L13_3818 +0.5 2.3 Benzoate 1,2-dioxygenase beta subunit (EC 1.14.12.10) compare
PfGW456L13_2699 +0.5 2.0 Exopolyphosphatase (EC 3.6.1.11) compare
PfGW456L13_200 +0.5 4.1 Glycosyl transferase in large core OS assembly cluster compare
PfGW456L13_3326 +0.5 2.1 FIG00953934: hypothetical protein compare
PfGW456L13_4711 +0.5 4.2 [Protein-PII] uridylyltransferase (EC 2.7.7.59) compare
PfGW456L13_199 +0.5 2.7 alpha-1,3-rhamnosyltransferase compare
PfGW456L13_3433 +0.5 1.3 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100) compare
PfGW456L13_75 +0.5 1.7 Putative multicopper oxidases compare
PfGW456L13_73 +0.5 0.9 FIG00955840: hypothetical protein compare
PfGW456L13_3012 +0.5 1.1 Fap amyloid fibril minor component compare
PfGW456L13_4936 +0.5 3.3 Cytochrome O ubiquinol oxidase subunit II (EC 1.10.3.-) compare
PfGW456L13_1669 +0.5 2.4 Na+-dependent transporters of the SNF family compare
PfGW456L13_3537 +0.5 1.4 Transcriptional regulator, ArsR family compare
PfGW456L13_3466 +0.5 1.4 Probable vanillate O-demethylase oxygenase subunit oxidoreductase protein (EC 1.14.13.-) compare
PfGW456L13_1300 +0.5 1.4 dTDP-4-dehydrorhamnose reductase (EC 1.1.1.133) compare
PfGW456L13_4008 +0.5 1.1 hypothetical protein compare
PfGW456L13_2271 +0.5 0.9 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
PfGW456L13_3954 +0.5 1.5 Probable hydrolase compare
PfGW456L13_3667 +0.5 1.2 hypothetical protein compare
PfGW456L13_468 +0.5 0.8 FIG00953394: hypothetical protein compare
PfGW456L13_4145 +0.5 3.1 Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
PfGW456L13_4096 +0.5 1.4 hypothetical protein compare
PfGW456L13_3874 +0.5 2.1 Transcriptional regulator, TetR family compare
PfGW456L13_66 +0.5 1.1 Cobalt-precorrin-8x methylmutase (EC 5.4.1.2) compare
PfGW456L13_2623 +0.5 0.7 NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3) compare
PfGW456L13_1524 +0.5 2.4 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
PfGW456L13_2277 +0.5 1.4 DNA-binding response regulator, LuxR family compare
PfGW456L13_2776 +0.5 1.1 Phage protein compare
PfGW456L13_621 +0.5 1.4 hypothetical protein compare
PfGW456L13_2024 +0.5 2.1 Arsenate reductase (EC 1.20.4.1) compare
PfGW456L13_4253 +0.4 1.2 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
PfGW456L13_3574 +0.4 2.3 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain compare
PfGW456L13_1990 +0.4 1.4 hypothetical protein compare
PfGW456L13_3302 +0.4 1.0 FIG00954674: hypothetical protein compare
PfGW456L13_1801 +0.4 1.6 FIG00954888: hypothetical protein compare
PfGW456L13_3372 +0.4 1.5 hypothetical protein compare
PfGW456L13_4933 +0.4 2.0 Cytochrome O ubiquinol oxidase subunit IV (EC 1.10.3.-) compare
PfGW456L13_758 +0.4 1.0 Phosphate regulon transcriptional regulatory protein PhoB (SphR) compare
PfGW456L13_1501 +0.4 1.7 Benzoate transport protein compare
PfGW456L13_2868 +0.4 0.8 hypothetical protein compare
PfGW456L13_1021 +0.4 1.7 Glutathione synthetase (EC 6.3.2.3) compare
PfGW456L13_1466 +0.4 2.1 FIG00953595: hypothetical protein compare
PfGW456L13_4618 +0.4 1.6 Outer membrane lipoprotein compare
PfGW456L13_1219 +0.4 1.3 hypothetical protein compare
PfGW456L13_3380 +0.4 1.7 hypothetical protein compare
PfGW456L13_3997 +0.4 1.9 hypothetical protein compare
PfGW456L13_3751 +0.4 1.5 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1; Vanillate O-demethylase oxidoreductase (EC 1.14.13.-) compare
PfGW456L13_5218 +0.4 1.1 tRNA-Pro-GGG compare
PfGW456L13_182 +0.4 2.1 ADP-ribose pyrophosphatase (EC 3.6.1.13) compare
PfGW456L13_3596 +0.4 1.9 Transcriptional regulator, AraC family compare
PfGW456L13_4836 +0.4 2.6 Transglycosylase, Slt family compare
PfGW456L13_3445 +0.4 0.9 hypothetical protein compare
PfGW456L13_1410 +0.4 2.0 NAD(FAD)-utilizing dehydrogenases compare
PfGW456L13_247 +0.4 1.1 FIG022199: FAD-binding protein compare
PfGW456L13_3727 +0.4 1.4 FIG00956189: hypothetical protein compare
PfGW456L13_3629 +0.4 0.6 Lactoylglutathione lyase and related lyases compare
PfGW456L13_3989 +0.4 1.8 FIG00964275: hypothetical protein compare
PfGW456L13_1131 +0.4 1.5 FIG00953361: hypothetical protein compare
PfGW456L13_2164 +0.4 1.6 Thioredoxin compare
PfGW456L13_3333 +0.4 1.3 hypothetical protein compare
PfGW456L13_844 +0.4 1.2 Diaminopimelate epimerase (EC 5.1.1.7) compare
PfGW456L13_1757 +0.4 2.1 Electron transport complex protein RnfB compare
PfGW456L13_2952 +0.4 1.1 2-ketogluconate utilization repressor PtxS compare
PfGW456L13_2990 +0.4 2.0 Dihydrofolate reductase (EC 1.5.1.3) compare
PfGW456L13_4365 +0.4 1.6 3-oxoacyl-[acyl-carrier-protein] synthase, KASIII (EC 2.3.1.180) compare
PfGW456L13_5029 +0.4 2.9 Cytoplasmic axial filament protein CafA and Ribonuclease G (EC 3.1.4.-) compare
PfGW456L13_843 +0.4 1.5 Protein of unknown function DUF484 compare
PfGW456L13_2380 +0.4 1.7 Lactoylglutathione lyase (EC 4.4.1.5) compare
PfGW456L13_498 +0.4 0.7 hypothetical protein compare
PfGW456L13_2438 +0.4 2.3 Transcriptional activator feaR compare
PfGW456L13_1438 +0.4 2.5 23S rRNA (guanine-N-2-) -methyltransferase rlmG (EC 2.1.1.-) compare
PfGW456L13_2191 +0.4 2.8 nucleotide sugar epimerase/dehydratase WbpM compare
PfGW456L13_4357 +0.4 1.9 Flagellar regulatory protein FleQ compare
PfGW456L13_5039 +0.4 1.6 4-carboxymuconolactone decarboxylase (EC 4.1.1.44) compare
PfGW456L13_2897 +0.4 1.2 hypothetical protein compare
PfGW456L13_770 +0.4 1.3 Superfamily II DNA and RNA helicases compare
PfGW456L13_4957 +0.4 2.4 FIG00957554: hypothetical protein compare
PfGW456L13_812 +0.4 1.3 D-amino acid dehydrogenase small subunit (EC 1.4.99.1) compare
PfGW456L13_3617 +0.4 1.7 TPR repeat precursor compare
PfGW456L13_1099 +0.4 1.1 FIG00953563: hypothetical protein compare
PfGW456L13_1784 +0.4 1.2 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
PfGW456L13_1745 +0.4 1.8 Alkyl hydroperoxide reductase subunit C-like protein compare
PfGW456L13_3028 +0.4 2.2 FIG00962948: hypothetical protein compare
PfGW456L13_2159 +0.4 0.7 hypothetical protein compare
PfGW456L13_4200 +0.4 1.7 hypothetical protein compare
PfGW456L13_3094 +0.4 2.3 formate dehydrogenase formation protein FdhE compare
PfGW456L13_1063 +0.4 1.5 hypothetical protein compare
PfGW456L13_2231 +0.4 1.7 Transcription elongation factor compare
PfGW456L13_2250 +0.4 2.4 Probable protease htpX homolog (EC 3.4.24.-) compare
PfGW456L13_1433 +0.4 1.7 DJ-1/YajL/PfpI superfamily, includes chaperone protein YajL (former ThiJ), parkinsonism-associated protein DJ-1, peptidases PfpI, Hsp31 compare
PfGW456L13_2430 +0.4 1.5 Acetyl-CoA acetyltransferase (EC 2.3.1.9) @ Beta-ketoadipyl CoA thiolase (EC 2.3.1.-) compare
PfGW456L13_3636 +0.4 1.3 Enoyl-CoA hydratase (EC 4.2.1.17) compare
PfGW456L13_1404 +0.4 2.1 Uncharacterized protein conserved in bacteria compare
PfGW456L13_3862 +0.4 0.6 DoxX family protein compare
PfGW456L13_607 +0.4 1.7 Heme A synthase, cytochrome oxidase biogenesis protein Cox15-CtaA compare
PfGW456L13_4072 +0.4 1.8 Adenine phosphoribosyltransferase (EC 2.4.2.7) compare
PfGW456L13_2118 +0.4 1.8 L-arabinolactonase (EC 3.1.1.15) (from data) compare
PfGW456L13_3443 +0.4 1.5 putative cytochrome P450 hydroxylase compare
PfGW456L13_3774 +0.3 1.0 Organic hydroperoxide resistance protein compare
PfGW456L13_2434 +0.3 1.5 Phenylacetate degradation enoyl-CoA hydratase PaaA (EC 4.2.1.17) compare
PfGW456L13_2382 +0.3 1.8 Glyoxalase family protein compare
PfGW456L13_2866 +0.3 2.0 Transcriptional regulator, IclR family compare
PfGW456L13_4925 +0.3 1.5 Probable glutathione S-transferase (EC 2.5.1.18), YfcF homolog compare
PfGW456L13_165 +0.3 1.8 Peptidase C14, caspase catalytic subunit p20 compare
PfGW456L13_581 +0.3 1.0 hypothetical protein compare
PfGW456L13_2529 +0.3 1.7 Alkanal monooxygenase alpha chain (EC 1.14.14.3) compare
PfGW456L13_4934 +0.3 2.2 Cytochrome O ubiquinol oxidase subunit III (EC 1.10.3.-) compare
PfGW456L13_3610 +0.3 0.8 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100) compare
PfGW456L13_1948 +0.3 0.9 Transcriptional regulator, LysR family compare
PfGW456L13_2196 +0.3 1.6 FIG00956575: hypothetical protein compare
PfGW456L13_2702 +0.3 1.5 Glycine cleavage system transcriptional activator compare
PfGW456L13_903 +0.3 2.0 Glycine cleavage system H protein compare
PfGW456L13_1409 +0.3 2.1 ATP-dependent RNA helicase PA3950 compare
PfGW456L13_4104 +0.3 1.5 Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
PfGW456L13_432 +0.3 1.4 Taurine transport ATP-binding protein TauB compare
PfGW456L13_392 +0.3 2.1 FIG00459469: hypothetical protein compare
PfGW456L13_3522 +0.3 1.8 Cytochrome C550 (Soluble cytochrome C) compare
PfGW456L13_4109 +0.3 1.5 Magnesium and cobalt transport protein CorA compare
PfGW456L13_3348 +0.3 0.7 Transcriptional regulator compare
PfGW456L13_2553 +0.3 2.0 ATP-dependent Clp protease ATP-binding subunit ClpX compare
PfGW456L13_3138 +0.3 1.0 phosphoesterase, putative compare
PfGW456L13_2547 +0.3 1.8 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
PfGW456L13_3440 +0.3 1.3 Aldehyde dehydrogenase (EC 1.2.1.3) compare
PfGW456L13_4769 +0.3 1.1 hypothetical protein compare
PfGW456L13_500 +0.3 0.8 FIG00954152: hypothetical protein compare
PfGW456L13_31 +0.3 1.3 Acyl dehydratase compare
PfGW456L13_421 +0.3 1.5 hypothetical protein compare
PfGW456L13_4479 +0.3 2.2 Sialic acid transporter (permease) NanT compare
PfGW456L13_1486 +0.3 1.7 hypothetical protein compare
PfGW456L13_4465 +0.3 1.8 3-oxoacyl-[acyl-carrier-protein] synthase, KASIII (EC 2.3.1.180) compare
PfGW456L13_2682 +0.3 1.4 Gll0911 protein compare
PfGW456L13_906 +0.3 1.2 Putative activity regulator of membrane protease YbbK compare
PfGW456L13_2445 +0.3 1.4 Cytosine deaminase (EC 3.5.4.1) compare
PfGW456L13_4918 +0.3 1.6 FIG00959654: hypothetical protein compare
PfGW456L13_2103 +0.3 1.4 Phosphate:acyl-ACP acyltransferase PlsX compare
PfGW456L13_1570 +0.3 1.2 hypothetical protein compare
PfGW456L13_1845 +0.3 1.0 Cold shock protein CspC compare
PfGW456L13_3750 +0.3 2.0 Transcriptional activator feaR compare
PfGW456L13_1344 +0.3 0.9 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase (EC 6.3.2.-) compare
PfGW456L13_3924 +0.3 0.9 Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family compare
PfGW456L13_4570 +0.3 1.9 FIG00953409: hypothetical protein compare
PfGW456L13_1819 +0.3 2.0 FIG00955538: hypothetical protein compare


Specific Phenotypes

For 6 genes in this experiment

For stress Zinc sulfate heptahydrate in Pseudomonas fluorescens GW456-L13

For stress Zinc sulfate heptahydrate across organisms