| Pathway | #Steps | #Present | #Specific |
|---|
| glycolate and glyoxylate degradation I | 4 | 4 | 4 |
| NAD salvage pathway IV (from nicotinamide riboside) | 2 | 2 | 2 |
| glycolate and glyoxylate degradation II | 2 | 2 | 2 |
| acetate conversion to acetyl-CoA | 1 | 1 | 1 |
| acetate and ATP formation from acetyl-CoA III | 1 | 1 | 1 |
| L-malate degradation I | 1 | 1 | 1 |
| long-chain fatty acid activation | 1 | 1 | 1 |
| superpathway of glycol metabolism and degradation | 7 | 7 | 5 |
| D-glucarate degradation I | 4 | 4 | 2 |
| D-galactarate degradation I | 4 | 4 | 2 |
| superoxide radicals degradation | 2 | 2 | 1 |
| glutathione degradation (DUG pathway) | 2 | 2 | 1 |
| polyphosphate metabolism | 2 | 2 | 1 |
| 2-O-α-mannosyl-D-glycerate degradation | 2 | 2 | 1 |
| chitin deacetylation | 4 | 3 | 2 |
| pyruvate fermentation to (R)-acetoin II | 2 | 1 | 1 |
| linoleate biosynthesis II (animals) | 2 | 1 | 1 |
| cinnamoyl-CoA biosynthesis | 2 | 1 | 1 |
| γ-linolenate biosynthesis II (animals) | 2 | 1 | 1 |
| NAD biosynthesis from nicotinamide | 2 | 1 | 1 |
| 2-methylcitrate cycle I | 5 | 5 | 2 |
| superpathway of D-glucarate and D-galactarate degradation | 5 | 5 | 2 |
| glyoxylate cycle | 6 | 6 | 2 |
| superpathway of acetate utilization and formation | 3 | 3 | 1 |
| ethanol degradation IV | 3 | 3 | 1 |
| cardiolipin biosynthesis I | 3 | 3 | 1 |
| cardiolipin biosynthesis II | 3 | 3 | 1 |
| L-homoserine biosynthesis | 3 | 3 | 1 |
| pentose phosphate pathway (oxidative branch) I | 3 | 3 | 1 |
| pyruvate fermentation to (S)-acetoin | 3 | 3 | 1 |
| ethanol degradation II | 3 | 3 | 1 |
| L-isoleucine biosynthesis IV | 6 | 4 | 2 |
| L-isoleucine biosynthesis V | 3 | 2 | 1 |
| ethanol degradation III | 3 | 2 | 1 |
| pyruvate fermentation to (R)-acetoin I | 3 | 2 | 1 |
| 3-methyl-branched fatty acid α-oxidation | 6 | 3 | 2 |
| oleate biosynthesis I (plants) | 3 | 1 | 1 |
| alkane biosynthesis II | 3 | 1 | 1 |
| glycolate and glyoxylate degradation III | 3 | 1 | 1 |
| C4 photosynthetic carbon assimilation cycle, NADP-ME type | 7 | 4 | 2 |
| reactive oxygen species degradation | 4 | 4 | 1 |
| L-valine biosynthesis | 4 | 4 | 1 |
| glycogen biosynthesis I (from ADP-D-Glucose) | 4 | 4 | 1 |
| cardiolipin and phosphatidylethanolamine biosynthesis (Xanthomonas) | 4 | 3 | 1 |
| phytol degradation | 4 | 3 | 1 |
| dipicolinate biosynthesis | 4 | 3 | 1 |
| phosphatidylcholine acyl editing | 4 | 2 | 1 |
| spermidine biosynthesis II | 4 | 2 | 1 |
| L-methionine biosynthesis IV | 4 | 2 | 1 |
| 2-deoxy-D-ribose degradation II | 8 | 3 | 2 |
| wax esters biosynthesis II | 4 | 1 | 1 |
| pinosylvin metabolism | 4 | 1 | 1 |
| glycogen biosynthesis II (from UDP-D-Glucose) | 4 | 1 | 1 |
| long chain fatty acid ester synthesis (engineered) | 4 | 1 | 1 |
| Entner-Doudoroff pathway II (non-phosphorylative) | 9 | 6 | 2 |
| photorespiration I | 9 | 5 | 2 |
| photorespiration III | 9 | 5 | 2 |
| sporopollenin precursors biosynthesis | 18 | 5 | 4 |
| superpathway of glyoxylate cycle and fatty acid degradation | 14 | 11 | 3 |
| C4 photosynthetic carbon assimilation cycle, PEPCK type | 14 | 9 | 3 |
| Rubisco shunt | 10 | 9 | 2 |
| 5,6-dehydrokavain biosynthesis (engineered) | 10 | 8 | 2 |
| pyruvate fermentation to isobutanol (engineered) | 5 | 4 | 1 |
| photorespiration II | 10 | 6 | 2 |
| starch biosynthesis | 10 | 6 | 2 |
| sphingosine and sphingosine-1-phosphate metabolism | 10 | 4 | 2 |
| superpathway of (R,R)-butanediol biosynthesis | 5 | 2 | 1 |
| octane oxidation | 5 | 2 | 1 |
| benzoate biosynthesis III (CoA-dependent, non-β-oxidative) | 5 | 2 | 1 |
| ectoine biosynthesis | 5 | 2 | 1 |
| superpathway of L-threonine biosynthesis | 6 | 6 | 1 |
| ppGpp metabolism | 6 | 6 | 1 |
| superpathway of glyoxylate bypass and TCA | 12 | 11 | 2 |
| fatty acid salvage | 6 | 5 | 1 |
| γ-glutamyl cycle | 6 | 5 | 1 |
| stearate biosynthesis II (bacteria and plants) | 6 | 5 | 1 |
| stearate biosynthesis IV | 6 | 4 | 1 |
| pyruvate fermentation to butanol II (engineered) | 6 | 4 | 1 |
| 2-methylcitrate cycle II | 6 | 4 | 1 |
| superpathway of 2,3-butanediol biosynthesis | 6 | 3 | 1 |
| 6-gingerol analog biosynthesis (engineered) | 6 | 2 | 1 |
| norspermidine biosynthesis | 6 | 2 | 1 |
| methylgallate degradation | 6 | 2 | 1 |
| superpathway of bitter acids biosynthesis | 18 | 3 | 3 |
| lupulone and humulone biosynthesis | 6 | 1 | 1 |
| β-alanine biosynthesis II | 6 | 1 | 1 |
| colupulone and cohumulone biosynthesis | 6 | 1 | 1 |
| stearate biosynthesis I (animals) | 6 | 1 | 1 |
| adlupulone and adhumulone biosynthesis | 6 | 1 | 1 |
| gluconeogenesis I | 13 | 13 | 2 |
| superpathway of L-isoleucine biosynthesis I | 13 | 13 | 2 |
| superpathway of cardiolipin biosynthesis (bacteria) | 13 | 11 | 2 |
| L-isoleucine biosynthesis I (from threonine) | 7 | 7 | 1 |
| ethene biosynthesis III (microbes) | 7 | 6 | 1 |
| L-lysine biosynthesis VI | 7 | 6 | 1 |
| L-lysine biosynthesis III | 7 | 6 | 1 |
| fatty acid β-oxidation I (generic) | 7 | 6 | 1 |
| anaerobic energy metabolism (invertebrates, cytosol) | 7 | 5 | 1 |
| L-isoleucine biosynthesis III | 7 | 4 | 1 |
| superpathway of NAD biosynthesis in eukaryotes | 14 | 7 | 2 |
| 3-dehydroquinate biosynthesis II (archaea) | 7 | 3 | 1 |
| D-xylose degradation IV | 7 | 3 | 1 |
| cremeomycin biosynthesis | 7 | 2 | 1 |
| ceramide degradation by α-oxidation | 7 | 2 | 1 |
| icosapentaenoate biosynthesis III (8-desaturase, mammals) | 7 | 1 | 1 |
| icosapentaenoate biosynthesis II (6-desaturase, mammals) | 7 | 1 | 1 |
| capsaicin biosynthesis | 7 | 1 | 1 |
| arachidonate biosynthesis III (6-desaturase, mammals) | 7 | 1 | 1 |
| pentose phosphate pathway | 8 | 8 | 1 |
| superpathway of L-homoserine and L-methionine biosynthesis | 8 | 8 | 1 |
| L-isoleucine biosynthesis II | 8 | 4 | 1 |
| glycogen biosynthesis III (from α-maltose 1-phosphate) | 8 | 3 | 1 |
| protocatechuate degradation I (meta-cleavage pathway) | 8 | 3 | 1 |
| ceramide and sphingolipid recycling and degradation (yeast) | 16 | 4 | 2 |
| grixazone biosynthesis | 8 | 2 | 1 |
| superpathway of polyamine biosynthesis III | 8 | 2 | 1 |
| L-arabinose degradation IV | 8 | 2 | 1 |
| superpathway of branched chain amino acid biosynthesis | 17 | 17 | 2 |
| superpathway of glucose and xylose degradation | 17 | 17 | 2 |
| superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass | 26 | 25 | 3 |
| oleate β-oxidation | 35 | 32 | 4 |
| L-lysine biosynthesis I | 9 | 9 | 1 |
| superpathway of S-adenosyl-L-methionine biosynthesis | 9 | 9 | 1 |
| Entner-Doudoroff pathway I | 9 | 9 | 1 |
| superpathway of L-methionine biosynthesis (transsulfuration) | 9 | 9 | 1 |
| 1-butanol autotrophic biosynthesis (engineered) | 27 | 19 | 3 |
| L-lysine biosynthesis II | 9 | 6 | 1 |
| reductive glycine pathway of autotrophic CO2 fixation | 9 | 6 | 1 |
| Entner-Doudoroff pathway III (semi-phosphorylative) | 9 | 6 | 1 |
| benzoate biosynthesis I (CoA-dependent, β-oxidative) | 9 | 4 | 1 |
| tunicamycin biosynthesis | 9 | 2 | 1 |
| cis-geranyl-CoA degradation | 9 | 1 | 1 |
| NiFe(CO)(CN)2 cofactor biosynthesis | 10 | 9 | 1 |
| glycolysis IV | 10 | 8 | 1 |
| glycolysis V (Pyrococcus) | 10 | 7 | 1 |
| superpathway of coenzyme A biosynthesis II (plants) | 10 | 5 | 1 |
| 3-phenylpropanoate degradation | 10 | 4 | 1 |
| superpathway of vanillin and vanillate degradation | 10 | 3 | 1 |
| suberin monomers biosynthesis | 20 | 3 | 2 |
| superpathway of fatty acid biosynthesis II (plant) | 43 | 38 | 4 |
| glycolysis II (from fructose 6-phosphate) | 11 | 11 | 1 |
| glycolysis III (from glucose) | 11 | 11 | 1 |
| glycolysis VI (from fructose) | 11 | 8 | 1 |
| pyruvate fermentation to hexanol (engineered) | 11 | 8 | 1 |
| homolactic fermentation | 12 | 12 | 1 |
| superpathway of phospholipid biosynthesis III (E. coli) | 12 | 12 | 1 |
| superpathway of L-methionine biosynthesis (by sulfhydrylation) | 12 | 10 | 1 |
| chorismate biosynthesis II (archaea) | 12 | 8 | 1 |
| syringate degradation | 12 | 3 | 1 |
| glycolysis I (from glucose 6-phosphate) | 13 | 13 | 1 |
| Calvin-Benson-Bassham cycle | 13 | 10 | 1 |
| photosynthetic 3-hydroxybutanoate biosynthesis (engineered) | 26 | 19 | 2 |
| formaldehyde assimilation I (serine pathway) | 13 | 8 | 1 |
| crotonyl-CoA/ethylmalonyl-CoA/hydroxybutyryl-CoA cycle (engineered) | 14 | 2 | 1 |
| superpathway of L-lysine, L-threonine and L-methionine biosynthesis II | 15 | 13 | 1 |
| Bifidobacterium shunt | 15 | 13 | 1 |
| palmitate biosynthesis II (type II fatty acid synthase) | 31 | 29 | 2 |
| superpathway of microbial D-galacturonate and D-glucuronate degradation | 31 | 19 | 2 |
| mixed acid fermentation | 16 | 16 | 1 |
| glycerol degradation to butanol | 16 | 11 | 1 |
| cutin biosynthesis | 16 | 2 | 1 |
| superpathway of glycolysis and the Entner-Doudoroff pathway | 17 | 17 | 1 |
| superpathway of anaerobic energy metabolism (invertebrates) | 17 | 12 | 1 |
| oxygenic photosynthesis | 17 | 11 | 1 |
| superpathway of hexitol degradation (bacteria) | 18 | 18 | 1 |
| superpathway of L-lysine, L-threonine and L-methionine biosynthesis I | 18 | 18 | 1 |
| superpathway of L-threonine metabolism | 18 | 16 | 1 |
| heterolactic fermentation | 18 | 16 | 1 |
| hexitol fermentation to lactate, formate, ethanol and acetate | 19 | 19 | 1 |
| superpathway of anaerobic sucrose degradation | 19 | 17 | 1 |
| superpathway of N-acetylneuraminate degradation | 22 | 22 | 1 |
| superpathway of cytosolic glycolysis (plants), pyruvate dehydrogenase and TCA cycle | 22 | 18 | 1 |
| aspartate superpathway | 25 | 24 | 1 |
| ethene biosynthesis V (engineered) | 25 | 18 | 1 |
| platensimycin biosynthesis | 26 | 6 | 1 |
| superpathway of fatty acids biosynthesis (E. coli) | 53 | 51 | 2 |
| palmitate biosynthesis III | 29 | 21 | 1 |
| superpathway of pentose and pentitol degradation | 42 | 18 | 1 |