Experiment set1IT036 for Pseudomonas sp. RS175

Compare to:

Sodium D,L-Lactate carbon 20 mM

200 most important genes:

  gene name fitness t score description  
PFR28_00063 -6.5 -4.5 Glycolate permease GlcA conserved
PFR28_00062 -5.9 -5.7 Lactate utilization protein A conserved
PFR28_00060 -5.9 -4.1 hypothetical protein conserved
PFR28_05016 -5.5 -13.4 Glutamate synthase [NADPH] small chain compare
PFR28_02824 -5.5 -6.6 3-isopropylmalate dehydratase large subunit compare
PFR28_04932 -5.4 -6.4 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase compare
PFR28_02821 -5.3 -16.1 3-isopropylmalate dehydrogenase compare
PFR28_03697 -5.3 -12.8 Ketol-acid reductoisomerase (NADP(+)) compare
PFR28_05015 -5.2 -22.1 Glutamate synthase [NADPH] large chain compare
PFR28_04278 -5.2 -10.0 Dihydroxy-acid dehydratase compare
PFR28_00061 -5.2 -11.6 Lactate utilization protein B conserved
PFR28_03363 -5.0 -13.7 Ornithine carbamoyltransferase 1, anabolic compare
PFR28_04933 -5.0 -4.8 Imidazole glycerol phosphate synthase subunit HisF compare
PFR28_04930 -4.9 -10.4 Imidazole glycerol phosphate synthase subunit HisH compare
PFR28_02823 -4.8 -3.3 3-isopropylmalate dehydratase small subunit 1 compare
PFR28_04832 -4.7 -12.2 putative phosphatase compare
PFR28_04986 -4.5 -6.9 Phosphoribosyl-AMP cyclohydrolase compare
PFR28_03860 -4.5 -6.8 putative murein peptide carboxypeptidase compare
PFR28_04929 -4.5 -6.1 Histidine biosynthesis bifunctional protein HisB compare
PFR28_05105 -4.5 -10.4 Phosphoserine phosphatase SerB2 compare
PFR28_02810 -4.4 -17.1 O-succinylhomoserine sulfhydrylase compare
PFR28_04245 -4.3 -16.1 Homoserine O-succinyltransferase compare
PFR28_01365 -4.3 -7.2 hypothetical protein compare
PFR28_02603 -4.3 -7.7 Siroheme synthase compare
PFR28_00188 -4.3 -13.3 Histidinol-phosphate aminotransferase compare
PFR28_00187 -4.2 -15.3 Histidinol dehydrogenase compare
PFR28_01366 -4.2 -10.5 Sulfite reductase [ferredoxin] compare
PFR28_00305 -4.2 -12.5 2-isopropylmalate synthase compare
PFR28_04202 -4.1 -2.9 5,10-methylenetetrahydrofolate reductase compare
PFR28_04246 -4.1 -13.0 Bifunctional methionine biosynthesis protein MetXA/MetW compare
PFR28_04985 -4.1 -5.8 Phosphoribosyl-ATP pyrophosphatase compare
PFR28_02811 -4.1 -4.8 Amidophosphoribosyltransferase compare
PFR28_03699 -4.0 -6.1 Acetolactate synthase isozyme 3 large subunit compare
PFR28_05244 -3.9 -17.9 Copper-exporting P-type ATPase compare
PFR28_05125 -3.8 -9.4 ATP phosphoribosyltransferase regulatory subunit compare
PFR28_04834 -3.7 -18.2 L-threonine dehydratase biosynthetic IlvA compare
PFR28_04842 -3.7 -7.1 D-3-phosphoglycerate dehydrogenase compare
PFR28_04517 -3.7 -16.2 Oxaloacetate decarboxylase alpha chain compare
PFR28_04519 -3.6 -8.6 HTH-type transcriptional activator CmpR compare
PFR28_04518 -3.6 -14.1 2-oxoglutarate carboxylase small subunit compare
PFR28_03217 -3.5 -3.3 Phosphoribosylformylglycinamidine cyclo-ligase compare
PFR28_00186 -3.4 -6.7 ATP phosphoribosyltransferase compare
PFR28_03012 -3.4 -8.6 Phosphate acyltransferase compare
PFR28_03223 -3.3 -16.4 GTP pyrophosphokinase compare
PFR28_04103 -3.1 -9.8 Biotin synthase compare
PFR28_03282 -3.1 -9.8 Arginine N-succinyltransferase subunit alpha compare
PFR28_03218 -3.0 -8.7 Phosphoribosylglycinamide formyltransferase compare
PFR28_04958 -2.8 -2.6 hypothetical protein compare
PFR28_03718 -2.7 -5.7 Transcriptional regulatory protein ZraR compare
PFR28_04308 -2.6 -4.3 Amino-acid acetyltransferase compare
PFR28_03698 -2.6 -10.5 Acetolactate synthase isozyme 3 small subunit compare
PFR28_00926 -2.6 -3.4 hypothetical protein compare
PFR28_04100 -2.5 -9.0 Malonyl-[acyl-carrier protein] O-methyltransferase compare
PFR28_04102 -2.4 -10.0 8-amino-7-oxononanoate synthase compare
PFR28_04208 -2.4 -7.1 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase compare
PFR28_02872 -2.3 -1.8 hypothetical protein compare
PFR28_00194 -2.3 -11.4 Bifunctional enzyme CysN/CysC compare
PFR28_04565 -2.2 -13.0 Protein RarD compare
PFR28_05005 -2.2 -10.9 NADP-dependent malic enzyme compare
PFR28_00837 -2.1 -6.7 hypothetical protein compare
PFR28_01156 -2.1 -6.4 hypothetical protein compare
PFR28_03388 -2.0 -12.5 Quinolinate synthase A compare
PFR28_00098 -2.0 -9.0 Nicotinate-nucleotide pyrophosphorylase [carboxylating] compare
PFR28_03369 -2.0 -6.5 Glycerol-3-phosphate regulon repressor compare
PFR28_03414 -1.9 -3.1 Crossover junction endodeoxyribonuclease RuvC compare
PFR28_03653 -1.9 -2.6 Molybdopterin-synthase adenylyltransferase compare
PFR28_03412 -1.9 -5.5 Holliday junction ATP-dependent DNA helicase RuvB compare
PFR28_03843 -1.9 -6.5 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase compare
PFR28_02484 -1.9 -9.0 UTP--glucose-1-phosphate uridylyltransferase compare
PFR28_00356 -1.9 -5.3 Protein-glutamate methylesterase/protein-glutamine glutaminase compare
PFR28_03420 -1.9 -5.3 hypothetical protein compare
PFR28_00918 -1.8 -8.1 UDP-N-acetylglucosamine 4,6-dehydratase (inverting) compare
PFR28_03664 -1.8 -3.7 Ribosome-binding ATPase YchF compare
PFR28_00966 -1.8 -12.2 HTH-type transcriptional regulator CysB compare
PFR28_05071 -1.8 -3.5 D-inositol-3-phosphate glycosyltransferase compare
PFR28_00193 -1.8 -9.6 Sulfate adenylyltransferase subunit 2 compare
PFR28_03304 -1.7 -1.8 hypothetical protein compare
PFR28_05000 -1.7 -2.8 Cell division protein FtsN compare
PFR28_03844 -1.6 -5.7 Thiamine-phosphate synthase compare
PFR28_03427 -1.6 -6.6 Sensor histidine kinase RcsC compare
PFR28_04072 -1.6 -4.2 Bifunctional folate synthesis protein compare
PFR28_01154 -1.5 -2.5 hypothetical protein compare
PFR28_04425 -1.5 -8.6 2-iminobutanoate/2-iminopropanoate deaminase compare
PFR28_04564 -1.4 -9.8 Aspartate-semialdehyde dehydrogenase compare
PFR28_04064 -1.4 -3.1 Ribosomal RNA small subunit methyltransferase A compare
PFR28_04566 -1.4 -8.7 4-chloro-allylglycine synthase compare
PFR28_00891 -1.4 -6.3 DNA-binding transcriptional regulator BolA compare
PFR28_02838 -1.4 -8.4 Aromatic-amino-acid aminotransferase compare
PFR28_04030 -1.4 -10.0 hypothetical protein compare
PFR28_03413 -1.4 -3.7 Holliday junction ATP-dependent DNA helicase RuvA compare
PFR28_04252 -1.4 -7.7 Thiazole synthase compare
PFR28_05091 -1.3 -10.4 Phosphomethylpyrimidine synthase compare
PFR28_03182 -1.3 -3.1 Recombination-associated protein RdgC compare
PFR28_00478 -1.3 -3.8 Transcriptional regulatory protein DegU compare
PFR28_05139 -1.3 -2.3 hypothetical protein compare
PFR28_04865 -1.3 -5.9 Glutamate--cysteine ligase compare
PFR28_04874 -1.3 -6.1 Phosphoenolpyruvate carboxykinase (ATP) compare
PFR28_03191 -1.3 -1.6 hypothetical protein compare
PFR28_00839 -1.2 -5.2 hypothetical protein compare
PFR28_02800 -1.2 -1.1 hypothetical protein compare
PFR28_02094 -1.2 -1.7 Glycerol-3-phosphate regulon repressor compare
PFR28_01372 -1.2 -2.4 Precorrin-4 C(11)-methyltransferase compare
PFR28_00695 -1.2 -2.3 Sulfur carrier protein TusA compare
PFR28_03721 -1.2 -4.0 3-methyl-2-oxobutanoate hydroxymethyltransferase compare
PFR28_00547 -1.2 -2.3 hypothetical protein compare
PFR28_01114 -1.2 -5.1 hypothetical protein compare
PFR28_01376 -1.1 -1.9 hypothetical protein compare
PFR28_04435 -1.1 -4.0 ATP-dependent DNA helicase RecG compare
PFR28_01876 -1.1 -1.5 hypothetical protein compare
PFR28_02704 -1.1 -1.2 hypothetical protein compare
PFR28_04071 -1.1 -1.5 Multifunctional CCA protein compare
PFR28_01258 -1.1 -3.6 1,4-dihydroxy-2-naphthoyl-CoA synthase compare
PFR28_05212 -1.1 -6.9 Sensor histidine kinase RcsC compare
PFR28_01933 -1.1 -1.8 Putative tartrate transporter compare
PFR28_04936 -1.0 -3.2 Carboxy-terminal processing protease CtpB compare
PFR28_04675 -1.0 -1.5 hypothetical protein compare
PFR28_03627 -1.0 -2.6 SOS response-associated protein YedK compare
PFR28_00480 -1.0 -4.1 HTH-type transcriptional activator CmpR compare
PFR28_04377 -1.0 -3.5 hypothetical protein compare
PFR28_04567 -1.0 -6.7 hypothetical protein compare
PFR28_00988 -1.0 -5.1 Sensor histidine kinase RcsC compare
PFR28_02608 -1.0 -1.5 DNA translocase FtsK compare
PFR28_04902 -1.0 -5.0 Inner membrane protein YgaZ compare
PFR28_00855 -1.0 -5.7 hypothetical protein compare
PFR28_04633 -0.9 -2.9 Alginate biosynthesis sensor protein KinB compare
PFR28_04232 -0.9 -3.7 Glutathione synthetase compare
PFR28_05205 -0.9 -2.9 Precorrin-8X methylmutase compare
PFR28_04585 -0.9 -4.2 Chromosome partitioning protein ParA compare
PFR28_03714 -0.9 -7.3 RNA polymerase-binding transcription factor DksA compare
PFR28_03837 -0.9 -5.1 Leucine-responsive regulatory protein compare
PFR28_01670 -0.9 -2.7 hypothetical protein compare
PFR28_04903 -0.9 -4.3 hypothetical protein compare
PFR28_03266 -0.9 -2.1 hypothetical protein compare
PFR28_01881 -0.9 -2.3 putative oxidoreductase compare
PFR28_00176 -0.9 -1.1 Lipopolysaccharide export system protein LptC compare
PFR28_00425 -0.9 -6.2 Protein-L-isoaspartate O-methyltransferase compare
PFR28_00980 -0.9 -1.6 ATP-dependent RNA helicase DeaD compare
PFR28_04931 -0.8 -1.6 hypothetical protein compare
PFR28_04040 -0.8 -1.4 Protein YhfA compare
PFR28_03430 -0.8 -4.7 Arginine biosynthesis bifunctional protein ArgJ compare
PFR28_01398 -0.8 -2.3 hypothetical protein compare
PFR28_01230 -0.8 -2.8 Lon protease compare
PFR28_03204 -0.8 -4.4 Cobyric acid synthase compare
PFR28_00069 -0.8 -2.4 Outer membrane protein assembly factor BamE compare
PFR28_03169 -0.8 -5.3 Tail-specific protease compare
PFR28_03281 -0.8 -3.7 Arginine N-succinyltransferase subunit beta compare
PFR28_01003 -0.8 -3.3 hypothetical protein compare
PFR28_01083 -0.8 -3.9 putative copper-importing P-type ATPase A compare
PFR28_03918 -0.8 -3.0 L-threonine 3-dehydrogenase compare
PFR28_04297 -0.8 -4.7 Gamma-glutamylputrescine synthetase PuuA compare
PFR28_04944 -0.8 -3.1 DNA-binding transcriptional regulator NtrC compare
PFR28_01600 -0.8 -1.7 HTH-type transcriptional regulator KdgR compare
PFR28_04569 -0.8 -3.6 HTH-type transcriptional regulator CdhR compare
PFR28_01930 -0.8 -2.3 HTH-type transcriptional regulator McbR compare
PFR28_02812 -0.8 -2.3 hypothetical protein compare
PFR28_00241 -0.8 -2.6 Disulfide bond formation protein B compare
PFR28_04724 -0.7 -4.5 NAD(P) transhydrogenase subunit alpha compare
PFR28_05058 -0.7 -5.7 hypothetical protein compare
PFR28_00861 -0.7 -5.4 Chemotaxis protein CheW compare
PFR28_00292 -0.7 -1.9 Protein IscX compare
PFR28_05068 -0.7 -1.8 hypothetical protein compare
PFR28_01118 -0.7 -2.1 hypothetical protein compare
PFR28_01378 -0.7 -1.7 Magnesium-chelatase 38 kDa subunit compare
PFR28_04723 -0.7 -5.6 NAD(P) transhydrogenase subunit beta compare
PFR28_05169 -0.7 -2.3 FMN-dependent NADH-azoreductase 1 compare
PFR28_03805 -0.7 -2.2 Aldehyde oxidoreductase iron-sulfur-binding subunit PaoA compare
PFR28_04725 -0.7 -4.9 NAD(P) transhydrogenase subunit alpha part 1 compare
PFR28_03283 -0.7 -3.3 Succinylornithine transaminase/acetylornithine aminotransferase compare
PFR28_01362 -0.7 -1.0 hypothetical protein compare
PFR28_01377 -0.7 -4.6 Aerobic cobaltochelatase subunit CobN compare
PFR28_00007 -0.7 -1.8 RecBCD enzyme subunit RecB compare
PFR28_00271 -0.7 -2.3 hypothetical protein compare
PFR28_00948 -0.7 -1.0 hypothetical protein compare
PFR28_03521 -0.7 -1.9 DNA repair protein RecO compare
PFR28_00460 -0.7 -2.0 hypothetical protein compare
PFR28_01408 -0.7 -2.1 hypothetical protein compare
PFR28_04369 -0.7 -1.2 hypothetical protein compare
PFR28_01212 -0.7 -1.5 hypothetical protein compare
PFR28_03322 -0.7 -1.8 hypothetical protein compare
PFR28_03916 -0.7 -1.1 hypothetical protein compare
PFR28_04904 -0.7 -3.8 HTH-type transcriptional regulator HdfR compare
PFR28_02688 -0.7 -1.4 hypothetical protein compare
PFR28_02990 -0.6 -1.8 hypothetical protein compare
PFR28_05199 -0.6 -3.1 Precorrin-6A reductase compare
PFR28_04378 -0.6 -2.3 Tyrosine recombinase XerC compare
PFR28_03208 -0.6 -4.2 Cobyrinate a,c-diamide synthase compare
PFR28_01231 -0.6 -1.7 Peptidyl-prolyl cis-trans isomerase D compare
PFR28_01470 -0.6 -1.8 Transcriptional regulatory protein WalR compare
PFR28_01092 -0.6 -1.9 Cbb3-type cytochrome c oxidase subunit CcoP1 compare
PFR28_01672 -0.6 -1.7 hypothetical protein compare
PFR28_03257 -0.6 -3.4 hypothetical protein compare
PFR28_01395 -0.6 -1.8 D-beta-hydroxybutyrate dehydrogenase compare
PFR28_03179 -0.6 -1.2 tRNA-Val compare
PFR28_03227 -0.6 -4.7 Signal transduction histidine-protein kinase BarA compare
PFR28_03877 -0.6 -1.9 Holin-like protein CidA compare
PFR28_05204 -0.6 -1.7 Sulfite reductase [ferredoxin] compare
PFR28_02616 -0.6 -5.0 Isocitrate dehydrogenase [NADP] compare
PFR28_01015 -0.6 -0.7 '3'-5' exonuclease DinG' transl_table=11 compare
PFR28_00873 -0.6 -3.3 hypothetical protein compare
PFR28_04344 -0.6 -2.1 Exopolyphosphatase compare


Specific Phenotypes

For 3 genes in this experiment

For carbon source Sodium D,L-Lactate in Pseudomonas sp. RS175

For carbon source Sodium D,L-Lactate across organisms