Experiment set1IT032 for Pontibacter actiniarum KMM 6156, DSM 19842

Compare to:

marine broth with Cisplatin 0.025 mg/ml

200 most detrimental genes:

  gene name fitness t score description  
CA264_05275 +3.0 9.2 MFS transporter compare
CA264_19970 +2.4 2.6 hypothetical protein compare
CA264_13660 +2.3 12.6 putative DNA modification/repair radical SAM protein compare
CA264_09340 +2.2 14.7 hypothetical protein compare
CA264_12605 +2.1 13.3 stress protection protein MarC compare
CA264_17020 +2.0 8.2 methyltransferase type 11 compare
CA264_01820 +1.8 9.6 hypothetical protein compare
CA264_12440 +1.7 1.9 methionyl-tRNA formyltransferase compare
CA264_07425 +1.5 10.4 AI-2E family transporter compare
CA264_13655 +1.5 9.0 DNA metabolism protein compare
CA264_19760 +1.4 4.8 hypothetical protein compare
CA264_17860 +1.4 7.6 tRNA dihydrouridine synthase DusB compare
CA264_01390 +1.4 8.0 iron ABC transporter permease compare
CA264_04415 +1.4 2.9 hypothetical protein compare
CA264_19770 +1.3 6.7 ATPase compare
CA264_03100 +1.3 8.7 Xaa-Pro aminopeptidase compare
CA264_20285 +1.2 3.3 hypothetical protein compare
CA264_07245 +1.2 6.7 hypothetical protein compare
CA264_19965 +1.2 5.6 dipeptidyl aminopeptidase compare
CA264_20060 +1.2 2.4 ribosome silencing factor RsfS compare
CA264_01385 +1.2 7.2 iron ABC transporter substrate-binding protein compare
CA264_09355 +1.1 3.0 nitroreductase compare
CA264_19220 +1.1 2.9 hypothetical protein compare
CA264_14515 +1.1 5.2 peptidase M23 compare
CA264_07185 +1.1 6.4 TetR family transcriptional regulator compare
CA264_20650 +1.0 4.4 diviva domain containing protein compare
CA264_19150 +1.0 6.9 TonB dependent receptor compare
CA264_17565 +1.0 1.7 hypothetical protein compare
CA264_18135 +1.0 3.9 ABC transporter ATP-binding protein compare
CA264_20615 +1.0 5.7 N-acetylmuramoyl-L-alanine amidase compare
CA264_04655 +1.0 5.4 cell division protein compare
CA264_21225 +1.0 2.8 hypothetical protein compare
CA264_14625 +1.0 1.1 phosphoribosylformylglycinamidine synthase subunit PurS compare
CA264_15850 +1.0 5.4 IclR family transcriptional regulator compare
CA264_03810 +1.0 2.4 hypothetical protein compare
CA264_10920 +1.0 5.7 helix-turn-helix-type transcriptional regulator compare
CA264_04895 +1.0 6.3 peptidase M23 compare
CA264_02685 +1.0 3.5 hypothetical protein compare
CA264_07020 +1.0 5.2 phosphatidylglycerophosphatase A compare
CA264_12610 +0.9 6.1 hypothetical protein compare
CA264_01805 +0.9 1.8 6-phosphogluconate dehydrogenase (decarboxylating) compare
CA264_00660 +0.9 5.6 hypothetical protein compare
CA264_14775 +0.9 2.8 hypothetical protein compare
CA264_17875 +0.9 1.6 amino acid dehydrogenase compare
CA264_18270 +0.9 1.8 hypothetical protein compare
CA264_12195 +0.9 2.2 DoxX family protein compare
CA264_15160 +0.9 3.1 nucleoside triphosphate pyrophosphohydrolase compare
CA264_02680 +0.8 2.3 RNA polymerase subunit sigma-70 compare
CA264_01815 +0.8 1.9 N-acetyltransferase compare
CA264_04350 +0.8 3.5 alanine dehydrogenase compare
CA264_01970 +0.8 3.2 multidrug ABC transporter ATP-binding protein compare
CA264_18345 +0.8 1.4 hypothetical protein compare
CA264_01065 +0.8 2.3 MarR family transcriptional regulator compare
CA264_11795 +0.8 5.3 aerotolerance regulator BatB compare
CA264_08250 +0.8 2.1 hypothetical protein compare
CA264_02690 +0.8 3.6 rhodanese compare
CA264_09070 +0.8 1.5 hypothetical protein compare
CA264_15150 +0.8 3.8 hypothetical protein compare
CA264_15880 +0.8 1.6 5-formyltetrahydrofolate cyclo-ligase compare
CA264_07260 +0.8 4.0 hypothetical protein compare
CA264_12625 +0.8 1.3 RDD family protein compare
CA264_17755 +0.8 4.7 ABC transporter compare
CA264_19960 +0.8 3.8 NUDIX hydrolase compare
CA264_09730 +0.8 2.1 hypothetical protein compare
CA264_07030 +0.8 4.2 UDP-glucose 4-epimerase compare
CA264_20115 +0.8 4.2 phosphoribosylamine--glycine ligase compare
CA264_12855 +0.8 1.5 hypothetical protein compare
CA264_00045 +0.8 4.6 endopeptidase La compare
CA264_03590 +0.8 1.9 hypothetical protein compare
CA264_12300 +0.8 2.5 RNase III inhibitor compare
CA264_19030 +0.7 2.1 ribosomal subunit interface protein compare
CA264_05930 +0.7 1.5 glyoxalase compare
CA264_00220 +0.7 1.9 pyrophosphatase compare
CA264_06330 +0.7 1.3 cation:proton antiporter compare
CA264_00170 +0.7 2.7 ATP:cob(I)alamin adenosyltransferase compare
CA264_01995 +0.7 4.7 SH3 domain-containing protein compare
CA264_17185 +0.7 2.2 peptide-methionine (R)-S-oxide reductase compare
CA264_18480 +0.7 0.9 hypothetical protein compare
CA264_13865 +0.7 1.3 hypothetical protein compare
CA264_17735 +0.7 5.0 antibiotic ABC transporter ATP-binding protein compare
CA264_16490 +0.7 3.4 glucose-1-phosphate thymidylyltransferase compare
CA264_14560 +0.7 1.2 VanZ family protein compare
CA264_06070 +0.7 1.3 kinase compare
CA264_16935 +0.7 1.9 hypothetical protein compare
CA264_01585 +0.7 2.8 hypothetical protein compare
CA264_18410 +0.7 1.8 glycine dehydrogenase (aminomethyl-transferring) compare
CA264_12005 +0.7 2.6 hypothetical protein compare
CA264_09740 +0.7 2.1 hypothetical protein compare
CA264_17560 +0.6 4.6 hypothetical protein compare
CA264_00745 +0.6 3.3 ribonuclease III compare
CA264_14840 +0.6 5.6 hypothetical protein compare
CA264_12940 +0.6 2.9 alcohol dehydrogenase compare
CA264_13860 +0.6 2.5 hypothetical protein compare
CA264_19830 +0.6 3.6 hypothetical protein compare
CA264_06990 +0.6 4.3 PA-phosphatase compare
CA264_19730 +0.6 5.0 peptidylprolyl isomerase compare
CA264_07590 +0.6 3.6 hypothetical protein compare
CA264_12785 +0.6 1.7 Rieske (2Fe-2S) protein compare
CA264_05075 +0.6 3.1 hypothetical protein compare
CA264_20945 +0.6 1.5 hypothetical protein compare
CA264_02195 +0.6 3.4 dioxygenase compare
CA264_01940 +0.6 1.8 antibiotic biosynthesis monooxygenase compare
CA264_14675 +0.6 1.5 hypothetical protein compare
CA264_09820 +0.6 2.5 hypothetical protein compare
CA264_09710 +0.6 0.9 transcriptional regulator compare
CA264_10255 +0.6 1.4 hypothetical protein compare
CA264_05630 +0.6 2.1 glycerol-3-phosphate dehydrogenase compare
CA264_17355 +0.6 3.3 ribonuclease R compare
CA264_20345 +0.6 1.7 hypothetical protein compare
CA264_01425 +0.6 4.5 RelA/SpoT family protein compare
CA264_09430 +0.6 2.8 2-isopropylmalate synthase compare
CA264_16105 +0.6 2.3 3-hydroxybutyryl-CoA dehydrogenase compare
CA264_07735 +0.6 1.5 hypothetical protein compare
CA264_20935 +0.6 1.0 transcriptional regulator compare
CA264_02695 +0.6 2.6 glycosyltransferase compare
CA264_17500 +0.6 1.6 molecular chaperone DnaK compare
CA264_19135 +0.6 2.0 hypothetical protein compare
CA264_14875 +0.6 4.2 hypothetical protein compare
CA264_07200 +0.6 3.1 glutamate dehydrogenase compare
CA264_21220 +0.6 4.4 hypothetical protein compare
CA264_09735 +0.6 1.2 5-hydroxyisourate hydrolase compare
CA264_12340 +0.5 1.8 acetyltransferase compare
CA264_17365 +0.5 2.3 rhomboid family intramembrane serine protease compare
CA264_15045 +0.5 3.2 acetyl-CoA acetyltransferase compare
CA264_14615 +0.5 2.6 MBL fold hydrolase compare
CA264_02945 +0.5 1.9 hypothetical protein compare
CA264_03635 +0.5 1.9 DoxX family protein compare
CA264_07570 +0.5 2.3 hypothetical protein compare
CA264_05080 +0.5 2.9 tryptophan synthase subunit beta compare
CA264_18765 +0.5 3.9 ATPase compare
CA264_10530 +0.5 1.3 hypothetical protein compare
CA264_09230 +0.5 1.2 hydroxymethylglutaryl-CoA lyase compare
CA264_12910 +0.5 1.1 acyl-CoA-binding protein compare
CA264_08805 +0.5 1.0 inosine/xanthosine triphosphatase compare
CA264_13495 +0.5 3.0 aldehyde dehydrogenase compare
CA264_18545 +0.5 3.8 DNA mismatch repair protein MutS compare
CA264_12800 +0.5 3.4 amino acid transporter compare
CA264_08015 +0.5 2.8 fructose-6-phosphate aldolase compare
CA264_12735 +0.5 1.3 hypothetical protein compare
CA264_16575 +0.5 1.8 hypothetical protein compare
CA264_08940 +0.5 1.8 cysteine synthase B compare
CA264_14485 +0.5 1.6 enoyl-CoA hydratase compare
CA264_08005 +0.5 0.7 phosphonate ABC transporter ATP-binding protein compare
CA264_15195 +0.5 1.9 phosphate ABC transporter substrate-binding protein, PhoT family compare
CA264_18005 +0.5 2.8 3-hydroxyanthranilate 3,4-dioxygenase compare
CA264_14835 +0.5 3.6 hypothetical protein compare
CA264_18275 +0.5 2.0 hypothetical protein compare
CA264_01595 +0.5 1.2 hypothetical protein compare
CA264_18630 +0.5 2.3 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
CA264_14975 +0.5 2.4 hypothetical protein compare
CA264_02565 +0.5 1.5 hypothetical protein compare
CA264_15715 +0.5 3.0 GTPase HflX compare
CA264_20070 +0.5 2.8 hypothetical protein compare
CA264_01800 +0.5 3.3 gluconate kinase compare
CA264_18015 +0.5 2.7 kynureninase compare
CA264_17740 +0.5 3.1 AraC family transcriptional regulator compare
CA264_19785 +0.5 3.7 TonB-dependent receptor compare
CA264_03480 +0.5 2.2 hypothetical protein compare
CA264_00730 +0.5 1.8 hypothetical protein compare
CA264_05025 +0.5 1.6 ATP phosphoribosyltransferase compare
CA264_07075 +0.5 1.7 hypothetical protein compare
CA264_08510 +0.5 1.6 thiol oxidoreductase compare
CA264_17680 +0.5 1.5 CoB--CoM heterodisulfide reductase compare
CA264_21555 +0.5 2.5 phosphoribosylpyrophosphate synthetase compare
CA264_20505 +0.5 1.7 hypothetical protein compare
CA264_04465 +0.5 2.9 alpha/beta hydrolase compare
CA264_05500 +0.5 1.4 hypothetical protein compare
CA264_00420 +0.5 1.7 fructose-bisphosphatase class I compare
CA264_11800 +0.5 2.9 aerotolerance protein compare
CA264_19865 +0.5 1.8 hypothetical protein compare
CA264_01790 +0.5 1.4 hypothetical protein compare
CA264_04460 +0.5 1.3 ABC transporter compare
CA264_13825 +0.5 0.8 hypothetical protein compare
CA264_03300 +0.4 1.1 hypothetical protein compare
CA264_02720 +0.4 2.6 peroxiredoxin compare
CA264_16820 +0.4 1.7 hypothetical protein compare
CA264_02020 +0.4 3.0 histidinol-phosphate transaminase compare
CA264_03610 +0.4 1.9 hypothetical protein compare
CA264_15450 +0.4 1.9 hypothetical protein compare
CA264_06995 +0.4 1.8 fatty acid hydroxylase compare
CA264_15790 +0.4 2.1 hypothetical protein compare
CA264_09165 +0.4 2.3 AraC family transcriptional regulator compare
CA264_12540 +0.4 2.0 glycoside hydrolase compare
CA264_15050 +0.4 3.8 3-hydroxyacyl-CoA dehydrogenase compare
CA264_05375 +0.4 3.1 hypothetical protein compare
CA264_15515 +0.4 2.4 peptidase compare
CA264_15725 +0.4 2.2 polyphosphate kinase 1 compare
CA264_13705 +0.4 2.3 30S ribosomal protein S6--L-glutamate ligase compare
CA264_07610 +0.4 1.7 chemotaxis protein CheW compare
CA264_05085 +0.4 2.3 tryptophan synthase subunit alpha compare
CA264_09065 +0.4 2.7 PAS domain-containing sensor histidine kinase compare
CA264_04340 +0.4 3.3 hypothetical protein compare
CA264_03800 +0.4 1.2 hypothetical protein compare
CA264_12890 +0.4 1.3 iron-binding protein compare
CA264_02925 +0.4 3.1 hypothetical protein compare
CA264_02725 +0.4 2.2 hypothetical protein compare
CA264_17045 +0.4 1.6 serine hydroxymethyltransferase compare
CA264_00435 +0.4 1.2 energy transducer TonB compare
CA264_01950 +0.4 2.1 PhoH family protein compare
CA264_12615 +0.4 2.4 peptidase M16 compare


Specific Phenotypes

For 6 genes in this experiment

For stress Cisplatin in Pontibacter actiniarum KMM 6156, DSM 19842

For stress Cisplatin across organisms