Experiment set1IT028 for Pseudomonas simiae WCS417

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a-Ketoglutaric acid disodium salt hydrate carbon source

200 most important genes:

  gene name fitness t score description  
PS417_01575 -6.3 -6.8 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
PS417_27040 -6.1 -5.7 3-phosphoglycerate dehydrogenase compare
PS417_18595 -6.0 -8.2 3-isopropylmalate dehydratase compare
PS417_25720 -5.8 -13.0 anthranilate synthase component II compare
PS417_27795 -5.5 -2.2 orotate phosphoribosyltransferase compare
PS417_23800 -5.4 -18.9 ketol-acid reductoisomerase compare
PS417_18585 -5.4 -10.3 3-isopropylmalate dehydrogenase compare
PS417_25725 -5.4 -21.8 anthranilate synthase component I compare
PS417_18560 -5.3 -11.5 N-(5'-phosphoribosyl)anthranilate isomerase compare
PS417_18600 -5.3 -6.3 isopropylmalate isomerase compare
PS417_26740 -5.3 -15.9 homoserine acetyltransferase compare
PS417_04415 -5.3 -13.2 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
PS417_01565 -5.2 -6.2 imidazole glycerol phosphate synthase compare
PS417_24745 -5.1 -7.5 gamma-glutamyl phosphate reductase compare
PS417_23805 -5.0 -8.5 acetolactate synthase 3 regulatory subunit compare
PS417_02005 -5.0 -15.9 glutamate synthase compare
PS417_16465 -5.0 -15.0 sirohydrochlorin ferrochelatase compare
PS417_01855 -5.0 -5.1 phosphoribosyl-AMP cyclohydrolase compare
PS417_23545 -4.9 -4.9 gamma-glutamyl kinase compare
PS417_01850 -4.8 -13.4 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
PS417_23810 -4.7 -13.8 acetolactate synthase 3 catalytic subunit compare
PS417_23995 -4.7 -1.8 preprotein translocase subunit SecG compare
PS417_06375 -4.7 -1.8 deoxycytidine triphosphate deaminase compare
PS417_02510 -4.6 -8.0 ATP phosphoribosyltransferase regulatory subunit compare
PS417_02000 -4.5 -19.8 glutamate synthase compare
PS417_27835 -4.5 -12.8 endoribonuclease compare
PS417_04420 -4.4 -11.4 histidinol dehydrogenase compare
PS417_26745 -4.3 -5.7 methionine biosynthesis protein MetW compare
PS417_26730 -4.3 -2.4 pyrroline-5-carboxylate reductase compare
PS417_00185 -4.2 -5.4 tryptophan synthase subunit beta compare
PS417_27195 -4.1 -2.2 N-acetylglutamate synthase compare
PS417_01605 -4.1 -3.9 phosphoglycerate mutase compare
PS417_20985 -3.9 -6.2 porin compare
PS417_12290 -3.8 -10.6 sulfite reductase compare
PS417_26995 -3.8 -13.9 phosphoserine phosphatase compare
PS417_18530 -3.6 -7.1 O-succinylhomoserine sulfhydrylase compare
PS417_05595 -3.6 -7.8 ornithine carbamoyltransferase compare
PS417_20125 -3.5 -7.3 phosphoribosylglycinamide formyltransferase compare
PS417_12855 -3.4 -9.3 3-phosphoshikimate 1-carboxyvinyltransferase compare
PS417_07640 -3.4 -6.3 glyceraldehyde-3-phosphate dehydrogenase compare
PS417_02415 -3.2 -7.1 phosphoserine phosphatase compare
PS417_25715 -3.2 -5.8 anthranilate phosphoribosyltransferase compare
PS417_26890 -3.2 -5.6 dihydroxy-acid dehydratase compare
PS417_00180 -3.2 -5.6 tryptophan synthase subunit alpha compare
PS417_23110 -3.1 -7.2 2-isopropylmalate synthase compare
PS417_08125 -3.0 -2.8 prephenate dehydratase compare
PS417_20160 -3.0 -3.6 cysteine synthase compare
PS417_01570 -2.7 -2.5 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase compare
PS417_01580 -2.7 -1.3 imidazole glycerol phosphate synthase compare
PS417_01950 -2.5 -8.8 malate dehydrogenase compare
PS417_24155 -2.5 -4.3 ATP-binding protein compare
PS417_25710 -2.4 -2.7 indole-3-glycerol-phosphate synthase compare
PS417_21705 -2.4 -8.6 arginine N-succinyltransferase compare
PS417_18690 -2.3 -7.4 aromatic amino acid aminotransferase compare
PS417_01560 -2.2 -4.0 imidazoleglycerol-phosphate dehydratase compare
PS417_22640 -2.1 -6.3 cytochrome C biogenesis protein CcmE conserved
PS417_08220 -2.1 -1.6 epimerase compare
PS417_07170 -2.0 -4.3 hypothetical protein compare
PS417_20610 -1.9 -3.1 hypothetical protein compare
PS417_08195 -1.7 -8.5 hypothetical protein compare
PS417_08205 -1.7 -7.1 acetyltransferase compare
PS417_23775 -1.7 -3.0 exodeoxyribonuclease V subunit beta compare
PS417_08245 -1.7 -2.1 CDP-6-deoxy-L-threo-D-glycero-4-hexulose-3- dehydrase reductase compare
PS417_08225 -1.6 -7.6 acetolactate synthase compare
PS417_08200 -1.6 -5.2 hypothetical protein compare
PS417_22650 -1.4 -10.6 MFS transporter conserved
PS417_24835 -1.4 -5.3 hypothetical protein compare
PS417_01210 -1.4 -8.4 hypothetical protein compare
PS417_22645 -1.4 -6.2 C4-dicarboxylate ABC transporter conserved
PS417_08230 -1.3 -2.9 lipopolysaccharide biosynthesis protein RfbH compare
PS417_26990 -1.2 -2.1 RNA pyrophosphohydrolase compare
PS417_00065 -1.2 -2.4 3-methyladenine DNA glycosylase compare
PS417_20665 -1.2 -6.0 hypothetical protein compare
PS417_21700 -1.1 -5.3 arginine N-succinyltransferase compare
PS417_22520 -1.1 -3.5 histidine kinase compare
PS417_13800 -1.1 -3.2 4-deoxy-4-formamido-L-arabinose-phospho-UDP deformylase compare
PS417_27010 -1.1 -6.6 threonine dehydratase compare
PS417_21425 -1.1 -2.4 4-amino-4-deoxychorismate lyase compare
PS417_21690 -1.1 -5.8 N-succinylarginine dihydrolase compare
PS417_05165 -1.1 -2.6 cytosol aminopeptidase compare
PS417_05570 -1.1 -4.9 DeoR faimly transcriptional regulator compare
PS417_01995 -1.1 -2.0 hypothetical protein compare
PS417_21125 -1.1 -5.9 phosphoadenosine phosphosulfate reductase compare
PS417_04410 -1.0 -1.5 hypothetical protein compare
PS417_23770 -1.0 -2.7 exodeoxyribonuclease V subunit alpha compare
PS417_22115 -1.0 -3.9 transcriptional regulator compare
PS417_18590 -1.0 -2.6 SAM-dependent methyltransferase compare
PS417_21020 -1.0 -7.9 phosphoenolpyruvate synthase compare
PS417_22450 -1.0 -1.8 ATP-dependent DNA helicase RuvA compare
PS417_17610 -1.0 -2.5 AsnC family transcriptional regulator compare
PS417_00570 -0.9 -4.6 NADP transhydrogenase subunit alpha compare
PS417_02555 -0.9 -7.5 exoribonuclease R compare
PS417_00565 -0.9 -3.1 NAD(P) transhydrogenase compare
PS417_07595 -0.9 -3.1 PasA protein compare
PS417_04585 -0.8 -1.3 hypothetical protein compare
PS417_02890 -0.8 -2.6 cobalt-precorrin-6X reductase compare
PS417_19605 -0.8 -1.9 hypothetical protein compare
PS417_20620 -0.8 -5.0 glycosyl transferase family 2 compare
PS417_04270 -0.8 -5.7 ribonuclease G compare
PS417_16490 -0.8 -2.6 cell division protein FtsK compare
PS417_06195 -0.8 -5.0 succinyldiaminopimelate aminotransferase compare
PS417_00560 -0.8 -6.2 NAD synthetase compare
PS417_08540 -0.8 -3.1 RNA helicase compare
PS417_13075 -0.8 -1.8 hypothetical protein compare
PS417_04365 -0.7 -0.6 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase compare
PS417_06200 -0.7 -3.9 protein-PII uridylyltransferase compare
PS417_23900 -0.7 -4.8 poly(A) polymerase compare
PS417_00755 -0.7 -1.0 biofilm PGA synthesis protein PgaD compare
PS417_02370 -0.7 -2.3 ADP-ribose pyrophosphatase compare
PS417_21480 -0.7 -1.6 23S rRNA pseudouridylate synthase compare
PS417_12565 -0.7 -1.4 2-dehydro-3-deoxygluconokinase compare
PS417_27870 -0.7 -3.2 ATP-dependent DNA helicase RecG compare
PS417_02690 -0.7 -3.4 N-acylglucosamine 2-epimerase compare
PS417_06895 -0.7 -2.5 DNA-binding protein compare
PS417_06970 -0.7 -1.7 LysR family transcriptional regulator compare
PS417_28070 -0.7 -3.2 phosphate ABC transporter ATP-binding protein compare
PS417_01710 -0.7 -4.3 histidine utilization repressor compare
PS417_06530 -0.7 -2.0 membrane protein compare
PS417_05455 -0.7 -3.9 XRE family transcriptional regulator compare
PS417_08580 -0.7 -4.0 histidine kinase compare
PS417_15095 -0.6 -1.7 hypothetical protein compare
PS417_23170 -0.6 -1.5 FeS assembly protein IscX compare
PS417_13510 -0.6 -1.2 polyketide cyclase compare
PS417_21725 -0.6 -2.3 amino acid transporter compare
PS417_18445 -0.6 -2.4 glycerol-3-phosphatase compare
PS417_08170 -0.6 -4.3 capsular biosynthesis protein compare
PS417_08990 -0.6 -2.3 ABC transporter substrate-binding protein compare
PS417_11705 -0.6 -4.2 cyclic peptide transporter compare
PS417_27435 -0.6 -4.2 polyphosphate kinase compare
PS417_04425 -0.6 -3.7 histidinol-phosphate aminotransferase compare
PS417_04375 -0.6 -2.0 ABC transporter ATP-binding protein compare
PS417_24615 -0.6 -1.1 hypothetical protein compare
PS417_26815 -0.6 -1.8 peptidase M16 compare
PS417_15085 -0.6 -2.7 ATPase AAA compare
PS417_21655 -0.6 -0.9 aspartate kinase compare
PS417_00295 -0.6 -3.0 hypothetical protein compare
PS417_03550 -0.6 -2.0 hypothetical protein compare
PS417_10220 -0.6 -2.3 hypothetical protein compare
PS417_13205 -0.6 -1.5 isochorismate-pyruvate lyase compare
PS417_07950 -0.6 -1.9 MFS transporter compare
PS417_04915 -0.6 -1.6 glutamine ABC transporter ATP-binding protein compare
PS417_15540 -0.6 -1.1 NUDIX hydrolase compare
PS417_23490 -0.6 -1.4 dihydrofolate reductase compare
PS417_19065 -0.6 -1.1 monooxygenase compare
PS417_17510 -0.6 -3.9 histidine kinase compare
PS417_18455 -0.6 -1.8 hypothetical protein compare
PS417_21510 -0.6 -1.2 histidine kinase compare
PS417_28080 -0.6 -4.6 phosphate ABC transporter permease compare
PS417_24620 -0.6 -1.5 hypothetical protein compare
PS417_12310 -0.6 -3.8 methionine synthase compare
PS417_22060 -0.6 -1.2 hypothetical protein compare
PS417_11440 -0.6 -1.8 hypothetical protein compare
PS417_00650 -0.6 -0.9 LysR family transcriptional regulator compare
PS417_05445 -0.5 -1.3 DNA mismatch repair protein MutT compare
PS417_27875 -0.5 -4.0 histidine kinase compare
PS417_01115 -0.5 -1.5 serine acetyltransferase compare
PS417_26445 -0.5 -2.0 ArsR family transcriptional regulator compare
PS417_09440 -0.5 -1.3 MerR family transcriptional regulator compare
PS417_05695 -0.5 -2.9 transcriptional regulator compare
PS417_00370 -0.5 -1.0 hypothetical protein compare
PS417_04650 -0.5 -1.0 D-alanine--D-alanine ligase compare
PS417_12505 -0.5 -2.3 peptidase compare
PS417_18420 -0.5 -1.5 deoxyribonuclease compare
PS417_08430 -0.5 -2.2 phospho-2-dehydro-3-deoxyheptonate aldolase compare
PS417_14200 -0.5 -1.5 hypothetical protein compare
PS417_00220 -0.5 -1.1 hypothetical protein compare
PS417_28075 -0.5 -2.5 phosphate ABC transporter permease compare
PS417_24785 -0.5 -1.0 nucleoside-diphosphate sugar epimerase compare
PS417_12355 -0.5 -1.5 magnesium chelatase compare
PS417_21750 -0.5 -4.6 acetyl-CoA synthetase compare
PS417_13050 -0.5 -1.3 N-acetylglucosamine-6-sulfatase compare
PS417_13710 -0.5 -1.4 hypothetical protein compare
PS417_13245 -0.5 -1.2 saccharopine dehydrogenase compare
PS417_25270 -0.5 -2.4 NrdR family transcriptional regulator compare
PS417_14980 -0.5 -0.9 universal stress protein UspA compare
PS417_17545 -0.5 -2.0 2-oxoisovalerate dehydrogenase compare
PS417_04775 -0.5 -2.6 short-chain dehydrogenase compare
PS417_15285 -0.5 -0.9 type VI secretion protein compare
PS417_22445 -0.5 -2.4 ATP-dependent DNA helicase RuvB compare
PS417_23375 -0.5 -1.5 cytochrome C oxidase compare
PS417_11180 -0.5 -2.0 TetR family transcriptional regulator compare
PS417_08685 -0.5 -1.3 flagellar hook-length control protein FliK compare
PS417_26725 -0.5 -2.6 hypothetical protein compare
PS417_19075 -0.5 -2.6 ABC transporter ATP-binding protein compare
PS417_26100 -0.5 -2.7 amino acid ABC transporter compare
PS417_08650 -0.5 -0.8 transcriptional regulator compare
PS417_18400 -0.5 -1.9 D-ribose ABC transporter, ATPase component RbsA (from data) compare
PS417_20030 -0.5 -1.6 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase compare
PS417_19195 -0.5 -2.0 hypothetical protein compare
PS417_26985 -0.5 -2.2 phosphoenolpyruvate-protein phosphotransferase compare
PS417_10370 -0.5 -2.2 ATPase compare
PS417_06835 -0.5 -1.5 phospholipase compare
PS417_08250 -0.5 -1.0 competence protein ComEA compare
PS417_07865 -0.5 -0.9 hypothetical protein compare
PS417_02700 -0.5 -2.0 urease accessory protein UreG compare
PS417_04220 -0.5 -1.1 4-carboxymuconolactone decarboxylase compare
PS417_12595 -0.5 -1.3 transcriptional regulator compare
PS417_05850 -0.5 -2.3 LysR family transcriptional regulator compare
PS417_17735 -0.5 -1.8 LacI family transcriptional regulator compare
PS417_19840 -0.5 -3.3 flagellar cap protein FliD compare


Specific Phenotypes

For 3 genes in this experiment

For carbon source a-Ketoglutaric acid disodium salt hydrate in Pseudomonas simiae WCS417

For carbon source a-Ketoglutaric acid disodium salt hydrate across organisms