Experiment set1IT027 for Pseudomonas fluorescens GW456-L13

Compare to:

D-Serine carbon source

200 most important genes:

  gene name fitness t score description  
PfGW456L13_1222 -6.3 -4.4 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
PfGW456L13_3947 -6.2 -4.3 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
PfGW456L13_1368 -6.1 -4.2 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
PfGW456L13_362 -5.8 -8.8 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
PfGW456L13_359 -5.7 -10.2 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
PfGW456L13_1540 -5.7 -9.4 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
PfGW456L13_2046 -5.6 -5.5 Glycerol-3-phosphate dehydrogenase [NAD(P)+] (EC 1.1.1.94) compare
PfGW456L13_3945 -5.6 -8.6 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
PfGW456L13_951 -5.6 -15.2 Phosphoserine phosphatase (EC 3.1.3.3) compare
PfGW456L13_779 -5.5 -12.8 Bona fide RidA/YjgF/TdcF/RutC subgroup compare
PfGW456L13_3940 -5.4 -9.8 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
PfGW456L13_845 -5.4 -7.3 Diaminopimelate decarboxylase (EC 4.1.1.20) compare
PfGW456L13_5001 -5.4 -9.6 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
PfGW456L13_5000 -5.3 -15.9 Histidinol dehydrogenase (EC 1.1.1.23) compare
PfGW456L13_728 -5.3 -17.2 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
PfGW456L13_1233 -5.2 -3.6 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) compare
PfGW456L13_4026 -5.2 -3.5 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
PfGW456L13_1221 -5.1 -14.8 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
PfGW456L13_1010 -5.1 -8.4 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) compare
PfGW456L13_1739 -5.1 -10.8 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
PfGW456L13_149 -5.0 -7.9 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
PfGW456L13_3948 -5.0 -8.3 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
PfGW456L13_913 -5.0 -9.5 N-acetylglutamate synthase (EC 2.3.1.1) compare
PfGW456L13_565 -5.0 -4.8 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
PfGW456L13_1472 -5.0 -7.5 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA compare
PfGW456L13_727 -4.9 -11.9 LysR family transcriptional regulator PA5437 compare
PfGW456L13_1205 -4.8 -9.6 Glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) compare
PfGW456L13_1217 -4.7 -18.1 Anthranilate synthase, aminase component (EC 4.1.3.27) compare
PfGW456L13_302 -4.7 -6.9 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
PfGW456L13_854 -4.6 -3.2 Argininosuccinate lyase (EC 4.3.2.1) compare
PfGW456L13_358 -4.6 -4.0 Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) compare
PfGW456L13_4165 -4.6 -5.4 Chorismate synthase (EC 4.2.3.5) compare
PfGW456L13_1972 -4.6 -3.1 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
PfGW456L13_1007 -4.6 -13.7 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
PfGW456L13_1538 -4.5 -14.9 Acetolactate synthase large subunit (EC 2.2.1.6) compare
PfGW456L13_1642 -4.5 -9.0 LppC putative lipoprotein compare
PfGW456L13_282 -4.5 -16.9 Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-) compare
PfGW456L13_3934 -4.4 -14.9 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
PfGW456L13_2103 -4.4 -8.3 Phosphate:acyl-ACP acyltransferase PlsX compare
PfGW456L13_793 -4.4 -4.2 Acetylglutamate kinase (EC 2.7.2.8) compare
PfGW456L13_3648 -4.3 -16.6 D-serine ammonia-lyase (EC 4.3.1.18) (from data) conserved
PfGW456L13_1749 -4.2 -4.1 Argininosuccinate synthase (EC 6.3.4.5) compare
PfGW456L13_656 -4.2 -4.1 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
PfGW456L13_1539 -4.2 -13.0 Acetolactate synthase small subunit (EC 2.2.1.6) compare
PfGW456L13_4859 -4.1 -2.8 Outer membrane protein YfgL, lipoprotein component of the protein assembly complex (forms a complex with YaeT, YfiO, and NlpB) compare
PfGW456L13_3647 -4.1 -17.9 D-serine dehydratase transcriptional activator conserved
PfGW456L13_1142 -4.1 -14.6 Protein rarD compare
PfGW456L13_2035 -4.0 -16.0 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) compare
PfGW456L13_361 -3.8 -12.6 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
PfGW456L13_275 -3.8 -2.6 3-dehydroquinate synthase (EC 4.2.3.4) compare
PfGW456L13_4031 -3.8 -3.4 Beta N-acetyl-glucosaminidase (EC 3.2.1.52) compare
PfGW456L13_50 -3.7 -11.6 3-dehydroquinate dehydratase II (EC 4.2.1.10) compare
PfGW456L13_276 -3.7 -2.1 Shikimate kinase I (EC 2.7.1.71) compare
PfGW456L13_2032 -3.6 -7.6 Cysteine synthase B (EC 2.5.1.47) compare
PfGW456L13_729 -3.6 -10.2 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
PfGW456L13_303 -3.6 -2.3 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
PfGW456L13_1235 -3.5 -12.3 Anhydro-N-acetylmuramic acid kinase (EC 2.7.1.-) compare
PfGW456L13_2034 -3.5 -2.8 hypothetical protein compare
PfGW456L13_644 -3.4 -10.9 Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) compare
PfGW456L13_973 -3.4 -14.8 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
PfGW456L13_5006 -3.4 -3.3 Uncharacterized ABC transporter, periplasmic component YrbD compare
PfGW456L13_1735 -3.4 -3.2 Glycerol uptake facilitator protein compare
PfGW456L13_4999 -3.4 -11.3 Histidinol-phosphate aminotransferase (EC 2.6.1.9) compare
PfGW456L13_1845 -3.3 -4.5 Cold shock protein CspC compare
PfGW456L13_874 -3.3 -19.2 Polyphosphate kinase (EC 2.7.4.1) compare
PfGW456L13_1863 -3.3 -11.1 Quinolinate synthetase (EC 2.5.1.72) compare
PfGW456L13_3649 -3.3 -8.6 D-serine permease (from data) conserved
PfGW456L13_5082 -3.3 -8.4 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
PfGW456L13_1615 -3.2 -3.1 Probable transmembrane protein compare
PfGW456L13_566 -3.2 -7.0 Tryptophan synthase beta chain (EC 4.2.1.20) compare
PfGW456L13_4854 -3.2 -9.0 2-isopropylmalate synthase (EC 2.3.3.13) compare
PfGW456L13_4088 -3.2 -3.1 Transcriptional regulator, GntR family compare
PfGW456L13_2176 -3.1 -6.6 Chorismate mutase I (EC 5.4.99.5) / Prephenate dehydratase (EC 4.2.1.51) compare
PfGW456L13_2385 -3.0 -3.4 PvdE, pyoverdine ABC export system, fused ATPase and permease components compare
PfGW456L13_1220 -3.0 -7.5 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
PfGW456L13_2842 -3.0 -7.5 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
PfGW456L13_1204 -2.9 -14.3 COG3178: Predicted phosphotransferase related to Ser/Thr protein kinases compare
PfGW456L13_1050 -2.9 -10.5 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
PfGW456L13_1150 -2.9 -15.4 Biotin synthesis protein BioC compare
PfGW456L13_1580 -2.9 -11.1 FIG140336: TPR domain protein compare
PfGW456L13_1006 -2.9 -5.0 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
PfGW456L13_1148 -2.9 -16.2 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
PfGW456L13_1553 -2.8 -12.0 Carbonic anhydrase (EC 4.2.1.1) compare
PfGW456L13_1973 -2.8 -7.2 Arginine N-succinyltransferase (EC 2.3.1.109) compare
PfGW456L13_1151 -2.8 -10.0 Dethiobiotin synthetase (EC 6.3.3.3) compare
PfGW456L13_2552 -2.7 -8.5 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
PfGW456L13_4012 -2.7 -3.6 VacJ-like lipoprotein precursor compare
PfGW456L13_1044 -2.7 -11.8 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
PfGW456L13_355 -2.6 -6.2 Carboxyl-terminal protease (EC 3.4.21.102) compare
PfGW456L13_2553 -2.6 -11.0 ATP-dependent Clp protease ATP-binding subunit ClpX compare
PfGW456L13_2221 -2.5 -13.9 ErfK/YbiS/YcfS/YnhG family protein compare
PfGW456L13_172 -2.5 -10.1 Phosphoserine phosphatase (EC 3.1.3.3) compare
PfGW456L13_5150 -2.5 -4.2 Exodeoxyribonuclease V alpha chain (EC 3.1.11.5) compare
PfGW456L13_757 -2.4 -3.1 Phosphate transport system regulatory protein PhoU compare
PfGW456L13_1655 -2.4 -3.8 D-alanine--D-alanine ligase (EC 6.3.2.4) compare
PfGW456L13_2656 -2.4 -8.2 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
PfGW456L13_140 -2.3 -5.2 FIG003573: hypothetical protein compare
PfGW456L13_949 -2.3 -12.9 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
PfGW456L13_952 -2.3 -6.8 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
PfGW456L13_144 -2.2 -6.1 3'-to-5' exoribonuclease RNase R compare
PfGW456L13_726 -2.1 -7.3 Phosphogluconate repressor HexR, RpiR family compare
PfGW456L13_4125 -2.1 -3.4 Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10) compare
PfGW456L13_1523 -2.1 -3.3 Poly(A) polymerase (EC 2.7.7.19) compare
PfGW456L13_4836 -2.1 -7.8 Transglycosylase, Slt family compare
PfGW456L13_2170 -2.1 -4.6 Similar to phosphoglycolate phosphatase, clustered with ubiquinone biosynthesis SAM-dependent O-methyltransferase compare
PfGW456L13_2551 -2.0 -2.4 Cell division trigger factor (EC 5.2.1.8) compare
PfGW456L13_5008 -2.0 -2.2 Uncharacterized ABC transporter, ATP-binding protein YrbF compare
PfGW456L13_150 -2.0 -1.3 hypothetical protein compare
PfGW456L13_4842 -2.0 -3.5 Translation elongation factor LepA compare
PfGW456L13_5005 -1.9 -5.1 Uncharacterized ABC transporter, auxiliary component YrbC compare
PfGW456L13_3960 -1.9 -9.0 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
PfGW456L13_4511 -1.9 -2.6 Rhodanese-like domain protein compare
PfGW456L13_1889 -1.9 -4.1 Phosphogluconate dehydratase (EC 4.2.1.12) compare
PfGW456L13_2843 -1.9 -7.6 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
PfGW456L13_990 -1.8 -4.8 Ribosomal RNA small subunit methyltransferase D (EC 2.1.1.-) compare
PfGW456L13_1981 -1.8 -4.2 Aspartokinase (EC 2.7.2.4) compare
PfGW456L13_1985 -1.8 -3.8 Alginate biosynthesis transcriptional activator compare
PfGW456L13_2237 -1.7 -1.6 Organic hydroperoxide resistance transcriptional regulator compare
PfGW456L13_943 -1.7 -4.8 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
PfGW456L13_3179 -1.7 -3.6 Organic hydroperoxide resistance transcriptional regulator compare
PfGW456L13_4207 -1.7 -5.0 Periplasmic protease compare
PfGW456L13_2250 -1.7 -7.7 Probable protease htpX homolog (EC 3.4.24.-) compare
PfGW456L13_953 -1.6 -10.5 FIG001592: Phosphocarrier protein kinase/phosphorylase, nitrogen regulation associated compare
PfGW456L13_5017 -1.6 -5.1 Hypothetical ATP-binding protein UPF0042, contains P-loop compare
PfGW456L13_1852 -1.6 -5.3 Holliday junction DNA helicase RuvA compare
PfGW456L13_5011 -1.6 -2.1 Uncharacterized protein YrbK clustered with lipopolysaccharide transporters compare
PfGW456L13_4451 -1.6 -4.6 ATP-dependent RNA helicase SrmB compare
PfGW456L13_1546 -1.5 -10.6 Paraquat-inducible protein B compare
PfGW456L13_1853 -1.5 -2.6 Holliday junction DNA helicase RuvB compare
PfGW456L13_2029 -1.5 -10.5 BarA sensory histidine kinase (= VarS = GacS) compare
PfGW456L13_784 -1.5 -6.8 Ribonuclease PH (EC 2.7.7.56) compare
PfGW456L13_1603 -1.5 -2.3 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
PfGW456L13_2651 -1.4 -2.8 Cell division protein FtsK compare
PfGW456L13_1011 -1.4 -3.3 Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC compare
PfGW456L13_928 -1.4 -6.5 Putrescine ABC transporter putrescine-binding protein PotF (TC 3.A.1.11.2) compare
PfGW456L13_4254 -1.4 -5.7 FIG00955360: hypothetical protein compare
PfGW456L13_1160 -1.4 -3.5 Putative DNA-binding protein in cluster with Type I restriction-modification system compare
PfGW456L13_1606 -1.4 -9.2 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
PfGW456L13_2885 -1.4 -7.0 BarA-associated response regulator UvrY (= GacA = SirA) compare
PfGW456L13_39 -1.4 -2.7 Permeases of the major facilitator superfamily compare
PfGW456L13_4009 -1.4 -8.0 Transaldolase (EC 2.2.1.2) compare
PfGW456L13_1574 -1.4 -3.8 GTP-binding and nucleic acid-binding protein YchF compare
PfGW456L13_1382 -1.4 -5.3 FOG: TPR repeat, SEL1 subfamily compare
PfGW456L13_1528 -1.4 -1.7 C4-type zinc finger protein, DksA/TraR family compare
PfGW456L13_4645 -1.4 -10.3 AmpG permease compare
PfGW456L13_4641 -1.4 -1.9 Deoxycytidine triphosphate deaminase (EC 3.5.4.13) compare
PfGW456L13_1198 -1.3 -5.4 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
PfGW456L13_2271 -1.3 -2.2 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
PfGW456L13_3667 -1.3 -0.9 hypothetical protein compare
PfGW456L13_3077 -1.3 -3.9 hypothetical protein compare
PfGW456L13_494 -1.3 -8.7 5-aminovalerate aminotransferase (EC 2.6.1.48) / Gamma-aminobutyrate:alpha-ketoglutarate aminotransferase (EC 2.6.1.19) compare
PfGW456L13_2956 -1.3 -3.9 Transcriptional regulatory protein RstA compare
PfGW456L13_1544 -1.3 -6.5 Paraquat-inducible protein A compare
PfGW456L13_1363 -1.3 -5.0 Rare lipoprotein A precursor compare
PfGW456L13_742 -1.3 -4.7 Aspartate ammonia-lyase (EC 4.3.1.1) compare
PfGW456L13_843 -1.2 -2.8 Protein of unknown function DUF484 compare
PfGW456L13_3398 -1.2 -3.5 Transcriptional regulator, TetR family compare
PfGW456L13_1524 -1.2 -5.8 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
PfGW456L13_4512 -1.2 -5.6 Exported zinc metalloprotease YfgC precursor compare
PfGW456L13_4639 -1.2 -3.1 Histidine ABC transporter, ATP-binding protein HisP (TC 3.A.1.3.1) compare
PfGW456L13_1153 -1.2 -6.9 Acyl-CoA dehydrogenase (EC 1.3.8.7) compare
PfGW456L13_2941 -1.2 -1.7 Glycerate kinase (EC 2.7.1.31) compare
PfGW456L13_652 -1.2 -3.1 Ribosomal RNA small subunit methyltransferase B (EC 2.1.1.-) compare
PfGW456L13_1842 -1.2 -7.0 Outer membrane porin, OprD family compare
PfGW456L13_360 -1.2 -2.0 FIG00956267: hypothetical protein compare
PfGW456L13_1545 -1.1 -5.5 Paraquat-inducible protein A compare
PfGW456L13_772 -1.1 -4.5 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
PfGW456L13_3047 -1.1 -2.7 Response regulator compare
PfGW456L13_3502 -1.1 -2.6 4-carboxymuconolactone decarboxylase domain/alkylhydroperoxidase AhpD family core domain protein compare
PfGW456L13_3845 -1.1 -1.4 Predicted secretion system X transmembrane protein 1 compare
PfGW456L13_4041 -1.1 -1.8 Enoyl-CoA hydratase (EC 4.2.1.17) / Delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase (EC 5.3.3.8) / 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) / 3-hydroxybutyryl-CoA epimerase (EC 5.1.2.3) compare
PfGW456L13_1020 -1.1 -4.6 Ferric siderophore transport system, periplasmic binding protein TonB compare
PfGW456L13_4145 -1.1 -5.0 Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
PfGW456L13_160 -1.1 -4.8 Epoxyqueuosine (oQ) reductase QueG compare
PfGW456L13_5086 -1.1 -3.0 tRNA pseudouridine synthase B (EC 4.2.1.70) compare
PfGW456L13_1140 -1.1 -1.5 Glycine cleavage system transcriptional antiactivator GcvR compare
PfGW456L13_2957 -1.1 -3.5 Sensory histidine kinase QseC compare
PfGW456L13_1386 -1.1 -9.5 Sensor histidine kinase compare
PfGW456L13_2632 -1.1 -2.6 NADH-ubiquinone oxidoreductase chain B (EC 1.6.5.3) compare
PfGW456L13_2979 -1.1 -3.3 hypothetical protein compare
PfGW456L13_852 -1.0 -1.2 FIG00954215: hypothetical protein compare
PfGW456L13_3300 -1.0 -6.9 MoxR-like ATPase in aerotolerance operon compare
PfGW456L13_44 -1.0 -3.3 Translation initiation factor SUI1-related protein compare
PfGW456L13_271 -1.0 -8.0 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
PfGW456L13_2223 -1.0 -5.4 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
PfGW456L13_1009 -1.0 -2.2 Integral membrane protein YggT, involved in response to extracytoplasmic stress (osmotic shock) compare
PfGW456L13_3260 -1.0 -1.3 hypothetical protein compare
PfGW456L13_5152 -1.0 -2.5 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
PfGW456L13_932 -1.0 -4.2 Putrescine transport system permease protein PotI (TC 3.A.1.11.2) compare
PfGW456L13_5060 -1.0 -3.2 Peptide chain release factor 3 compare
PfGW456L13_151 -1.0 -2.2 HflC protein compare
PfGW456L13_4733 -1.0 -2.1 SAM-dependent methyltransferase (EC 2.1.1.-) compare
PfGW456L13_4217 -1.0 -1.5 Sodium-dependent transporter compare
PfGW456L13_1913 -1.0 -5.3 Ribonuclease BN (EC 3.1.-.-) compare
PfGW456L13_927 -0.9 -6.6 Omega-amino acid--pyruvate aminotransferase (EC 2.6.1.18) compare
PfGW456L13_2857 -0.9 -1.2 ChlD component of cobalt chelatase involved in B12 biosynthesis compare
PfGW456L13_930 -0.9 -5.4 Putrescine transport ATP-binding protein PotG (TC 3.A.1.11.2) compare
PfGW456L13_272 -0.9 -8.3 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
PfGW456L13_4668 -0.9 -2.9 RecA protein compare
PfGW456L13_4218 -0.9 -1.8 Quaternary ammonium compound-resistance protein SugE compare


Specific Phenotypes

For 5 genes in this experiment

For carbon source D-Serine in Pseudomonas fluorescens GW456-L13

For carbon source D-Serine across organisms