Experiment set1IT026 for Pseudomonas fluorescens GW456-L13

Compare to:

L-Tryptophan carbon source

200 most important genes:

  gene name fitness t score description  
PfGW456L13_172 -6.5 -6.4 Phosphoserine phosphatase (EC 3.1.3.3) compare
PfGW456L13_727 -6.4 -7.6 LysR family transcriptional regulator PA5437 compare
PfGW456L13_362 -6.2 -7.4 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
PfGW456L13_149 -6.2 -6.0 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
PfGW456L13_2842 -6.2 -4.3 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
PfGW456L13_303 -6.2 -3.7 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
PfGW456L13_3948 -6.1 -4.2 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
PfGW456L13_3934 -6.1 -9.4 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
PfGW456L13_358 -6.1 -3.1 Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) compare
PfGW456L13_1007 -6.0 -8.3 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
PfGW456L13_644 -5.9 -8.1 Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) compare
PfGW456L13_1010 -5.9 -5.7 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) compare
PfGW456L13_361 -5.8 -11.9 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
PfGW456L13_1540 -5.8 -6.9 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
PfGW456L13_1472 -5.8 -5.6 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA compare
PfGW456L13_845 -5.6 -3.9 Diaminopimelate decarboxylase (EC 4.1.1.20) compare
PfGW456L13_359 -5.5 -9.9 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
PfGW456L13_2046 -5.4 -6.5 Glycerol-3-phosphate dehydrogenase [NAD(P)+] (EC 1.1.1.94) compare
PfGW456L13_5096 -5.4 -3.6 FIG004454: RNA binding protein compare
PfGW456L13_2176 -5.4 -10.6 Chorismate mutase I (EC 5.4.99.5) / Prephenate dehydratase (EC 4.2.1.51) compare
PfGW456L13_913 -5.3 -7.3 N-acetylglutamate synthase (EC 2.3.1.1) compare
PfGW456L13_973 -5.3 -14.5 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
PfGW456L13_2032 -5.3 -3.6 Cysteine synthase B (EC 2.5.1.47) compare
PfGW456L13_5001 -5.3 -10.7 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
PfGW456L13_4999 -5.2 -12.2 Histidinol-phosphate aminotransferase (EC 2.6.1.9) compare
PfGW456L13_1739 -5.2 -10.0 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
PfGW456L13_951 -5.2 -14.2 Phosphoserine phosphatase (EC 3.1.3.3) compare
PfGW456L13_3945 -5.1 -12.8 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
PfGW456L13_5000 -5.1 -15.7 Histidinol dehydrogenase (EC 1.1.1.23) compare
PfGW456L13_3947 -5.1 -6.9 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
PfGW456L13_4585 -5.0 -4.6 Beta-ketoadipate enol-lactone hydrolase (EC 3.1.1.24) compare
PfGW456L13_1538 -4.9 -9.5 Acetolactate synthase large subunit (EC 2.2.1.6) compare
PfGW456L13_1603 -4.8 -3.2 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
PfGW456L13_793 -4.8 -3.3 Acetylglutamate kinase (EC 2.7.2.8) compare
PfGW456L13_1539 -4.8 -12.0 Acetolactate synthase small subunit (EC 2.2.1.6) compare
PfGW456L13_2843 -4.8 -10.6 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
PfGW456L13_1050 -4.8 -10.1 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
PfGW456L13_728 -4.8 -14.3 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
PfGW456L13_812 -4.7 -3.2 D-amino acid dehydrogenase small subunit (EC 1.4.99.1) compare
PfGW456L13_2230 -4.6 -10.7 Cys regulon transcriptional activator CysB compare
PfGW456L13_1368 -4.6 -6.7 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
PfGW456L13_1233 -4.6 -4.4 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) compare
PfGW456L13_854 -4.5 -3.1 Argininosuccinate lyase (EC 4.3.2.1) compare
PfGW456L13_4590 -4.4 -6.0 Beta-ketoadipyl CoA thiolase (EC 2.3.1.-) compare
PfGW456L13_729 -4.4 -11.8 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
PfGW456L13_1006 -4.4 -6.6 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
PfGW456L13_943 -4.4 -9.6 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
PfGW456L13_1749 -4.4 -3.0 Argininosuccinate synthase (EC 6.3.4.5) compare
PfGW456L13_779 -4.4 -11.0 Bona fide RidA/YjgF/TdcF/RutC subgroup compare
PfGW456L13_2034 -4.3 -2.5 hypothetical protein compare
PfGW456L13_1151 -4.3 -12.2 Dethiobiotin synthetase (EC 6.3.3.3) compare
PfGW456L13_4594 -4.2 -16.7 Pca regulon regulatory protein PcaR conserved
PfGW456L13_4026 -4.1 -3.1 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
PfGW456L13_4229 -4.1 -15.3 Long-chain fatty acid transport protein compare
PfGW456L13_4859 -4.1 -2.8 Outer membrane protein YfgL, lipoprotein component of the protein assembly complex (forms a complex with YaeT, YfiO, and NlpB) compare
PfGW456L13_1198 -4.1 -6.7 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
PfGW456L13_1972 -4.0 -3.1 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
PfGW456L13_1153 -4.0 -13.3 Acyl-CoA dehydrogenase (EC 1.3.8.7) compare
PfGW456L13_2551 -4.0 -4.7 Cell division trigger factor (EC 5.2.1.8) compare
PfGW456L13_4041 -4.0 -2.7 Enoyl-CoA hydratase (EC 4.2.1.17) / Delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase (EC 5.3.3.8) / 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) / 3-hydroxybutyryl-CoA epimerase (EC 5.1.2.3) compare
PfGW456L13_2656 -4.0 -8.2 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
PfGW456L13_1973 -4.0 -6.6 Arginine N-succinyltransferase (EC 2.3.1.109) compare
PfGW456L13_4592 -3.9 -11.0 3-oxoadipate CoA-transferase subunit A (EC 2.8.3.6) (from data) conserved
PfGW456L13_302 -3.9 -6.0 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
PfGW456L13_1524 -3.9 -7.9 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
PfGW456L13_3824 -3.8 -3.2 Muconate cycloisomerase (EC 5.5.1.1) compare
PfGW456L13_4165 -3.8 -5.4 Chorismate synthase (EC 4.2.3.5) compare
PfGW456L13_4088 -3.8 -3.5 Transcriptional regulator, GntR family compare
PfGW456L13_5086 -3.7 -5.7 tRNA pseudouridine synthase B (EC 4.2.1.70) compare
PfGW456L13_1147 -3.7 -14.6 Biotin synthase (EC 2.8.1.6) compare
PfGW456L13_275 -3.7 -2.5 3-dehydroquinate synthase (EC 4.2.3.4) compare
PfGW456L13_4740 -3.7 -10.4 Phosphoenolpyruvate carboxylase (EC 4.1.1.31) compare
PfGW456L13_5060 -3.7 -3.6 Peptide chain release factor 3 compare
PfGW456L13_1584 -3.7 -4.1 Molybdopterin biosynthesis protein MoeB compare
PfGW456L13_5082 -3.7 -8.1 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
PfGW456L13_276 -3.6 -1.5 Shikimate kinase I (EC 2.7.1.71) compare
PfGW456L13_4288 -3.6 -14.6 Kynureninase (EC 3.7.1.3) (from data) conserved
PfGW456L13_751 -3.6 -5.3 cytosolic long-chain acyl-CoA thioester hydrolase family protein compare
PfGW456L13_3960 -3.5 -9.8 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
PfGW456L13_1148 -3.5 -16.0 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
PfGW456L13_2035 -3.5 -11.3 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) compare
PfGW456L13_1553 -3.4 -9.8 Carbonic anhydrase (EC 4.2.1.1) compare
PfGW456L13_1863 -3.4 -10.6 Quinolinate synthetase (EC 2.5.1.72) compare
PfGW456L13_4038 -3.4 -2.3 DNA topoisomerase I (EC 5.99.1.2) compare
PfGW456L13_1150 -3.4 -15.5 Biotin synthesis protein BioC compare
PfGW456L13_852 -3.4 -1.4 FIG00954215: hypothetical protein compare
PfGW456L13_811 -3.4 -6.2 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system compare
PfGW456L13_4292 -3.4 -6.3 Tryptophan 2,3-dioxygenase (EC 1.13.11.11) (from data) conserved
PfGW456L13_1911 -3.3 -10.4 Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) compare
PfGW456L13_4854 -3.3 -9.5 2-isopropylmalate synthase (EC 2.3.3.13) compare
PfGW456L13_350 -3.3 -5.7 Protein export cytoplasm chaperone protein (SecB, maintains protein to be exported in unfolded state) compare
PfGW456L13_329 -3.2 -5.8 Histidine utilization repressor compare
PfGW456L13_4591 -3.2 -4.5 3-oxoadipate CoA-transferase subunit B (EC 2.8.3.6) (from data) compare
PfGW456L13_2552 -3.2 -8.7 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
PfGW456L13_4589 -3.2 -6.3 Protocatechuate 3,4-dioxygenase beta chain (EC 1.13.11.3) compare
PfGW456L13_1009 -3.2 -3.5 Integral membrane protein YggT, involved in response to extracytoplasmic stress (osmotic shock) compare
PfGW456L13_5067 -3.2 -13.8 Ornithine decarboxylase (EC 4.1.1.17) / Arginine decarboxylase (EC 4.1.1.19) compare
PfGW456L13_150 -3.2 -2.0 hypothetical protein compare
PfGW456L13_50 -3.1 -9.5 3-dehydroquinate dehydratase II (EC 4.2.1.10) compare
PfGW456L13_427 -3.1 -2.6 Two-component system response regulator OmpR compare
PfGW456L13_1847 -3.1 -1.8 Glycerate kinase (EC 2.7.1.31) compare
PfGW456L13_2103 -3.1 -6.1 Phosphate:acyl-ACP acyltransferase PlsX compare
PfGW456L13_1044 -3.0 -10.8 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
PfGW456L13_3894 -3.0 -1.5 Integration host factor alpha subunit compare
PfGW456L13_784 -3.0 -7.7 Ribonuclease PH (EC 2.7.7.56) compare
PfGW456L13_5150 -3.0 -4.4 Exodeoxyribonuclease V alpha chain (EC 3.1.11.5) compare
PfGW456L13_4842 -2.9 -3.9 Translation elongation factor LepA compare
PfGW456L13_5089 -2.9 -1.9 Transcription termination protein NusA compare
PfGW456L13_4170 -2.9 -6.2 Isochorismatase (EC 3.3.2.1) compare
PfGW456L13_3823 -2.8 -4.1 Muconolactone isomerase (EC 5.3.3.4) (from data) conserved
PfGW456L13_1479 -2.8 -1.1 FKBP-type peptidyl-prolyl cis-trans isomerase SlpA (EC 5.2.1.8) compare
PfGW456L13_4293 -2.8 -11.2 Kynurenine formamidase, bacterial (EC 3.5.1.9) (from data) conserved
PfGW456L13_4145 -2.7 -8.6 Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
PfGW456L13_1845 -2.7 -5.0 Cold shock protein CspC compare
PfGW456L13_1735 -2.6 -4.6 Glycerol uptake facilitator protein compare
PfGW456L13_5008 -2.6 -2.5 Uncharacterized ABC transporter, ATP-binding protein YrbF compare
PfGW456L13_2636 -2.6 -5.3 FIG002776: hypothetical protein compare
PfGW456L13_3398 -2.6 -3.9 Transcriptional regulator, TetR family compare
PfGW456L13_1824 -2.5 -2.3 transcriptional regulator MvaT, P16 subunit compare
PfGW456L13_4289 -2.5 -9.7 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system conserved
PfGW456L13_990 -2.5 -3.2 Ribosomal RNA small subunit methyltransferase D (EC 2.1.1.-) compare
PfGW456L13_3810 -2.5 -2.2 hypothetical protein compare
PfGW456L13_949 -2.4 -11.6 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
PfGW456L13_1615 -2.4 -2.5 Probable transmembrane protein compare
PfGW456L13_5006 -2.4 -3.0 Uncharacterized ABC transporter, periplasmic component YrbD compare
PfGW456L13_4961 -2.4 -6.6 Fumarylacetoacetase (EC 3.7.1.2) compare
PfGW456L13_67 -2.4 -6.7 Cobalamin biosynthesis protein CobG compare
PfGW456L13_926 -2.3 -10.0 glutamine synthetase family protein compare
PfGW456L13_757 -2.3 -2.2 Phosphate transport system regulatory protein PhoU compare
PfGW456L13_4009 -2.3 -7.6 Transaldolase (EC 2.2.1.2) compare
PfGW456L13_430 -2.3 -9.3 Glutamate--cysteine ligase (EC 6.3.2.2) compare
PfGW456L13_1838 -2.2 -6.3 Sensory box histidine kinase compare
PfGW456L13_477 -2.2 -1.7 Alkanesulfonates ABC transporter ATP-binding protein / Sulfonate ABC transporter, ATP-binding subunit SsuB compare
PfGW456L13_2221 -2.2 -8.2 ErfK/YbiS/YcfS/YnhG family protein compare
PfGW456L13_4511 -2.2 -1.9 Rhodanese-like domain protein compare
PfGW456L13_5121 -2.2 -1.2 hypothetical protein compare
PfGW456L13_2885 -2.2 -7.2 BarA-associated response regulator UvrY (= GacA = SirA) compare
PfGW456L13_2631 -2.2 -3.1 NADH-ubiquinone oxidoreductase chain C (EC 1.6.5.3) / NADH-ubiquinone oxidoreductase chain D (EC 1.6.5.3) compare
PfGW456L13_4882 -2.1 -3.5 tRNA-guanine transglycosylase (EC 2.4.2.29) compare
PfGW456L13_355 -2.1 -4.7 Carboxyl-terminal protease (EC 3.4.21.102) compare
PfGW456L13_5017 -2.1 -2.6 Hypothetical ATP-binding protein UPF0042, contains P-loop compare
PfGW456L13_1453 -2.1 -8.5 Glutathione-regulated potassium-efflux system ATP-binding protein compare
PfGW456L13_3822 -2.1 -8.2 Catechol 1,2-dioxygenase (EC 1.13.11.1) (from data) conserved
PfGW456L13_4125 -2.0 -2.7 Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10) compare
PfGW456L13_2029 -2.0 -9.4 BarA sensory histidine kinase (= VarS = GacS) compare
PfGW456L13_2237 -2.0 -2.1 Organic hydroperoxide resistance transcriptional regulator compare
PfGW456L13_3179 -2.0 -3.9 Organic hydroperoxide resistance transcriptional regulator compare
PfGW456L13_1580 -1.9 -6.6 FIG140336: TPR domain protein compare
PfGW456L13_360 -1.9 -2.1 FIG00956267: hypothetical protein compare
PfGW456L13_5005 -1.9 -5.2 Uncharacterized ABC transporter, auxiliary component YrbC compare
PfGW456L13_2436 -1.9 -4.7 Phenylacetic acid degradation operon negative regulatory protein PaaX compare
PfGW456L13_1574 -1.8 -3.1 GTP-binding and nucleic acid-binding protein YchF compare
PfGW456L13_2739 -1.8 -7.5 Anthranilate 1,2-dioxygenase (deaminating, decarboxylating) (EC 1.14.12.1) (from data) conserved
PfGW456L13_4478 -1.8 -4.1 Lactam utilization protein LamB compare
PfGW456L13_3825 -1.7 -2.1 Aromatic hydrocarbon utilization transcriptional regulator CatR (LysR family) compare
PfGW456L13_2553 -1.7 -6.0 ATP-dependent Clp protease ATP-binding subunit ClpX compare
PfGW456L13_1139 -1.7 -7.2 Malate synthase G (EC 2.3.3.9) compare
PfGW456L13_777 -1.7 -10.0 Nucleoside-diphosphate-sugar epimerases compare
PfGW456L13_4042 -1.7 -2.4 FIG00953628: hypothetical protein compare
PfGW456L13_1655 -1.7 -1.3 D-alanine--D-alanine ligase (EC 6.3.2.4) compare
PfGW456L13_421 -1.7 -2.0 hypothetical protein compare
PfGW456L13_1981 -1.7 -3.8 Aspartokinase (EC 2.7.2.4) compare
PfGW456L13_4451 -1.7 -4.2 ATP-dependent RNA helicase SrmB compare
PfGW456L13_527 -1.6 -2.5 Transcriptional regulator compare
PfGW456L13_4668 -1.6 -4.5 RecA protein compare
PfGW456L13_902 -1.6 -7.7 Aminomethyltransferase (glycine cleavage system T protein) (EC 2.1.2.10) compare
PfGW456L13_4012 -1.6 -2.4 VacJ-like lipoprotein precursor compare
PfGW456L13_213 -1.6 -9.5 Glutamate-ammonia-ligase adenylyltransferase (EC 2.7.7.42) compare
PfGW456L13_352 -1.6 -3.5 FIG136845: Rhodanese-related sulfurtransferase compare
PfGW456L13_118 -1.6 -2.3 hypothetical protein compare
PfGW456L13_3303 -1.5 -6.1 BatA (Bacteroides aerotolerance operon) compare
PfGW456L13_2740 -1.5 -8.8 Anthranilate 1,2-dioxygenase (deaminating, decarboxylating) (EC 1.14.12.1) (from data) conserved
PfGW456L13_4108 -1.5 -2.0 CrfX protein compare
PfGW456L13_1020 -1.5 -4.8 Ferric siderophore transport system, periplasmic binding protein TonB compare
PfGW456L13_3304 -1.5 -5.8 TPR domain protein in aerotolerance operon compare
PfGW456L13_4477 -1.5 -2.1 Allophanate hydrolase 2 subunit 1 (EC 3.5.1.54) compare
PfGW456L13_2273 -1.5 -3.3 Molybdenum cofactor biosynthesis protein MoaB compare
PfGW456L13_4512 -1.5 -4.8 Exported zinc metalloprotease YfgC precursor compare
PfGW456L13_140 -1.5 -2.3 FIG003573: hypothetical protein compare
PfGW456L13_1021 -1.5 -5.4 Glutathione synthetase (EC 6.3.2.3) compare
PfGW456L13_155 -1.5 -4.4 tRNA dimethylallyltransferase (EC 2.5.1.75) compare
PfGW456L13_426 -1.4 -6.5 Osmolarity sensory histidine kinase EnvZ compare
PfGW456L13_843 -1.4 -3.4 Protein of unknown function DUF484 compare
PfGW456L13_4579 -1.4 -6.1 Transcription repressor of multidrug efflux pump acrAB operon, TetR (AcrR) family compare
PfGW456L13_4517 -1.4 -10.1 L-aspartate oxidase (EC 1.4.3.16) compare
PfGW456L13_62 -1.4 -1.2 hypothetical protein compare
PfGW456L13_600 -1.4 -5.8 Zinc ABC transporter, inner membrane permease protein ZnuB compare
PfGW456L13_3808 -1.4 -2.6 Predicted transcriptional regulator of NADH dehydrogenase, Rrf2 family compare
PfGW456L13_1936 -1.4 -0.9 RNA polymerase sigma-70 factor, ECF subfamily compare
PfGW456L13_351 -1.4 -2.4 Glutaredoxin 3 (Grx3) compare
PfGW456L13_125 -1.4 -0.9 hypothetical protein compare
PfGW456L13_2768 -1.4 -2.2 FIG00959468: hypothetical protein compare
PfGW456L13_2741 -1.4 -4.4 hypothetical protein compare
PfGW456L13_322 -1.4 -2.6 Histidine ABC transporter, ATP-binding protein (TC 3.A.1) compare
PfGW456L13_1528 -1.4 -1.7 C4-type zinc finger protein, DksA/TraR family compare
PfGW456L13_1363 -1.4 -3.7 Rare lipoprotein A precursor compare
PfGW456L13_4118 -1.4 -5.6 Methylisocitrate lyase (EC 4.1.3.30) compare
PfGW456L13_4155 -1.3 -3.3 Spermidine synthase (EC 2.5.1.16) compare
PfGW456L13_874 -1.3 -8.5 Polyphosphate kinase (EC 2.7.4.1) compare
PfGW456L13_1525 -1.3 -5.7 Two-component sensor CbrA: intrcellular carbon:nitrogen balance compare


Specific Phenotypes

For 18 genes in this experiment

For carbon source L-Tryptophan in Pseudomonas fluorescens GW456-L13

For carbon source L-Tryptophan across organisms