Experiment set1IT026 for Pseudomonas fluorescens GW456-L13

Compare to:

L-Tryptophan carbon source

200 most detrimental genes:

  gene name fitness t score description  
PfGW456L13_204 +3.9 29.7 Carbamoyltransferase in large core OS assembly cluster compare
PfGW456L13_200 +3.6 30.9 Glycosyl transferase in large core OS assembly cluster compare
PfGW456L13_199 +3.4 24.1 alpha-1,3-rhamnosyltransferase compare
PfGW456L13_2191 +3.1 20.6 nucleotide sugar epimerase/dehydratase WbpM compare
PfGW456L13_2185 +3.1 7.1 putative colanic acid biosynthesis glycosyl transferase compare
PfGW456L13_203 +2.9 16.9 Glycosyl transferase in large core OS assembly cluster compare
PfGW456L13_205 +2.8 8.6 hypothetical protein compare
PfGW456L13_202 +2.6 13.8 Probable transcription regulator Mig-14 compare
PfGW456L13_2095 +2.6 6.8 Ribonuclease E (EC 3.1.26.12) compare
PfGW456L13_743 +2.5 10.1 Transcriptional regulator compare
PfGW456L13_578 +2.5 16.1 Glutamate-aspartate carrier protein compare
PfGW456L13_1889 +2.5 8.4 Phosphogluconate dehydratase (EC 4.2.1.12) compare
PfGW456L13_787 +2.4 14.8 Exodeoxyribonuclease III (EC 3.1.11.2) compare
PfGW456L13_144 +2.4 11.4 3'-to-5' exoribonuclease RNase R compare
PfGW456L13_4936 +2.4 16.7 Cytochrome O ubiquinol oxidase subunit II (EC 1.10.3.-) compare
PfGW456L13_1968 +2.3 14.5 Arginine pathway regulatory protein ArgR, repressor of arg regulon compare
PfGW456L13_1637 +2.3 10.9 Stringent starvation protein A compare
PfGW456L13_4932 +2.3 15.9 Heme O synthase, protoheme IX farnesyltransferase (EC 2.5.1.-) COX10-CtaB compare
PfGW456L13_4935 +2.3 16.9 Cytochrome O ubiquinol oxidase subunit I (EC 1.10.3.-) compare
PfGW456L13_4582 +2.2 9.3 RND efflux system, outer membrane lipoprotein CmeC compare
PfGW456L13_2190 +2.2 8.2 Undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase (EC 2.7.8.-) compare
PfGW456L13_4934 +2.2 11.4 Cytochrome O ubiquinol oxidase subunit III (EC 1.10.3.-) compare
PfGW456L13_2189 +2.1 10.2 UDP-2,3-diacetamido-2,3-dideoxy-D-mannuronic acid transferase compare
PfGW456L13_201 +2.1 10.0 Hypothetical protein FIG015671 in large core OS assembly cluster compare
PfGW456L13_4253 +2.0 6.2 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
PfGW456L13_1966 +2.0 16.4 Arginine/ornithine ABC transporter, permease protein AotM compare
PfGW456L13_1967 +2.0 6.4 Arginine/ornithine ABC transporter, ATP-binding protein AotP compare
PfGW456L13_1970 +2.0 13.7 hypothetical protein compare
PfGW456L13_1964 +2.0 16.6 Arginine/ornithine ABC transporter, periplasmic arginine/ornithine binding protein compare
PfGW456L13_1965 +2.0 14.0 Arginine/ornithine ABC transporter, permease protein AotQ compare
PfGW456L13_4933 +2.0 9.2 Cytochrome O ubiquinol oxidase subunit IV (EC 1.10.3.-) compare
PfGW456L13_742 +1.9 6.8 Aspartate ammonia-lyase (EC 4.3.1.1) compare
PfGW456L13_1971 +1.8 10.4 Succinylornithine transaminase (EC 2.6.1.81) compare
PfGW456L13_1834 +1.7 9.9 Glutamate N-acetyltransferase (EC 2.3.1.35) / N-acetylglutamate synthase (EC 2.3.1.1) compare
PfGW456L13_43 +1.7 15.1 Biosynthetic arginine decarboxylase (EC 4.1.1.19) compare
PfGW456L13_1300 +1.7 5.0 dTDP-4-dehydrorhamnose reductase (EC 1.1.1.133) compare
PfGW456L13_1337 +1.6 8.1 DedA protein compare
PfGW456L13_4863 +1.6 2.9 FIG021952: putative membrane protein compare
PfGW456L13_2957 +1.6 5.7 Sensory histidine kinase QseC compare
PfGW456L13_4580 +1.5 8.2 Multidrug efflux RND membrane fusion protein MexC compare
PfGW456L13_4545 +1.5 1.8 Integral membrane protein compare
PfGW456L13_1745 +1.5 6.1 Alkyl hydroperoxide reductase subunit C-like protein compare
PfGW456L13_4581 +1.5 11.0 RND efflux system, inner membrane transporter CmeB compare
PfGW456L13_1916 +1.4 2.3 hypothetical protein compare
PfGW456L13_364 +1.4 4.3 FIG00958480: hypothetical protein compare
PfGW456L13_4433 +1.4 2.7 FIG00955751: hypothetical protein compare
PfGW456L13_3050 +1.3 2.4 hypothetical protein compare
PfGW456L13_5003 +1.2 2.4 YrbA protein compare
PfGW456L13_2033 +1.2 4.1 23S rRNA (Uracil-5-) -methyltransferase RumA (EC 2.1.1.-) ## LSU rRNA m(5)U1939 compare
PfGW456L13_804 +1.2 0.8 hypothetical protein compare
PfGW456L13_4955 +1.2 2.1 FIG00954638: hypothetical protein compare
PfGW456L13_872 +1.2 6.4 FIG139438: lipoprotein B compare
PfGW456L13_2981 +1.2 1.9 Probable acyl-CoA dehydrogenase (EC 1.3.99.3) compare
PfGW456L13_1235 +1.2 6.7 Anhydro-N-acetylmuramic acid kinase (EC 2.7.1.-) compare
PfGW456L13_1441 +1.1 1.8 Large-conductance mechanosensitive channel compare
PfGW456L13_1850 +1.1 6.2 FIG000859: hypothetical protein YebC compare
PfGW456L13_4064 +1.1 2.8 Cytochrome c oxidase subunit CcoP (EC 1.9.3.1) compare
PfGW456L13_4645 +1.1 8.9 AmpG permease compare
PfGW456L13_1391 +1.1 1.1 Transcriptional regulator, AsnC family compare
PfGW456L13_740 +1.1 6.8 L-asparaginase (EC 3.5.1.1) (from data) compare
PfGW456L13_272 +1.1 10.2 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
PfGW456L13_4741 +1.1 3.3 FIG00958830: hypothetical protein compare
PfGW456L13_3667 +1.1 1.9 hypothetical protein compare
PfGW456L13_858 +1.1 4.0 Uroporphyrinogen-III synthase (EC 4.2.1.75) compare
PfGW456L13_2954 +1.1 6.1 RND efflux system, inner membrane transporter CmeB compare
PfGW456L13_741 +1.1 9.3 sodium/alanine transporter compare
PfGW456L13_2589 +1.0 3.8 Methylglutaconyl-CoA hydratase (EC 4.2.1.18) compare
PfGW456L13_1636 +1.0 4.7 ubiquinol cytochrome C oxidoreductase, cytochrome C1 subunit compare
PfGW456L13_789 +1.0 4.0 hypothetical protein compare
PfGW456L13_4264 +1.0 8.0 Branched-chain amino acid transport system carrier protein compare
PfGW456L13_3232 +1.0 1.8 hypothetical protein compare
PfGW456L13_2594 +1.0 5.6 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) compare
PfGW456L13_931 +1.0 5.8 Putrescine transport system permease protein PotH (TC 3.A.1.11.2) compare
PfGW456L13_577 +1.0 4.5 Fused spore maturation proteins A and B compare
PfGW456L13_739 +1.0 4.3 Transcriptional regulator, AraC family compare
PfGW456L13_4896 +1.0 1.5 hypothetical protein compare
PfGW456L13_2608 +1.0 1.4 Peptidyl-prolyl cis-trans isomerase PpiB (EC 5.2.1.8) compare
PfGW456L13_2504 +1.0 2.7 4-oxalocrotonate decarboxylase (EC 4.1.1.77) compare
PfGW456L13_579 +1.0 2.3 hypothetical protein compare
PfGW456L13_1729 +1.0 3.3 YaeQ protein compare
PfGW456L13_4259 +1.0 1.2 FIG00953296: hypothetical protein compare
PfGW456L13_207 +1.0 4.1 InaA protein compare
PfGW456L13_859 +1.0 4.1 Uncharacterized protein EC-HemY, likely associated with heme metabolism based on gene clustering with hemC, hemD in Proteobacteria (unrelated to HemY-type PPO in GramPositives) compare
PfGW456L13_866 +1.0 4.1 Small-conductance mechanosensitive channel compare
PfGW456L13_5047 +1.0 6.4 ABC transporter, ATP-binding protein compare
PfGW456L13_375 +0.9 7.4 transport permease protein of gamma-aminobutyrate compare
PfGW456L13_903 +0.9 5.0 Glycine cleavage system H protein compare
PfGW456L13_3291 +0.9 1.3 4-carboxymuconolactone decarboxylase domain/alkylhydroperoxidase AhpD family core domain protein compare
PfGW456L13_795 +0.9 1.8 hypothetical protein compare
PfGW456L13_1714 +0.9 1.5 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
PfGW456L13_1181 +0.9 1.5 hypothetical protein compare
PfGW456L13_2800 +0.9 1.2 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system compare
PfGW456L13_4790 +0.9 6.3 D-serine/D-alanine/glycine transporter compare
PfGW456L13_4924 +0.9 4.5 Lysine 2,3-aminomutase (EC 5.4.3.2) compare
PfGW456L13_1192 +0.9 2.7 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) compare
PfGW456L13_4067 +0.9 5.4 Type cbb3 cytochrome oxidase biogenesis protein CcoI; Copper-translocating P-type ATPase (EC 3.6.3.4) compare
PfGW456L13_498 +0.9 1.1 hypothetical protein compare
PfGW456L13_5049 +0.9 4.7 Sensor histidine kinase PrrB (RegB) (EC 2.7.3.-) compare
PfGW456L13_420 +0.9 1.3 Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49) compare
PfGW456L13_1204 +0.9 5.8 COG3178: Predicted phosphotransferase related to Ser/Thr protein kinases compare
PfGW456L13_930 +0.9 6.2 Putrescine transport ATP-binding protein PotG (TC 3.A.1.11.2) compare
PfGW456L13_2184 +0.9 2.3 putative polysaccharide polymerase compare
PfGW456L13_2956 +0.9 3.6 Transcriptional regulatory protein RstA compare
PfGW456L13_1523 +0.9 2.0 Poly(A) polymerase (EC 2.7.7.19) compare
PfGW456L13_573 +0.9 2.1 FIG00955509: hypothetical protein compare
PfGW456L13_2186 +0.8 3.0 UDP-N-acetylglucosamine 4,6-dehydratase (EC 4.2.1.-) compare
PfGW456L13_839 +0.8 2.0 FIG004064: hypothetical protein compare
PfGW456L13_1534 +0.8 5.8 FIG00955330: hypothetical protein compare
PfGW456L13_3333 +0.8 1.6 hypothetical protein compare
PfGW456L13_4062 +0.8 4.3 Cytochrome c oxidase subunit CcoO (EC 1.9.3.1) compare
PfGW456L13_153 +0.8 4.7 GTP-binding protein HflX compare
PfGW456L13_1205 +0.8 3.6 Glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) compare
PfGW456L13_346 +0.8 3.1 Nitrogen regulation protein NtrB (EC 2.7.13.3) compare
PfGW456L13_3034 +0.8 1.6 hypothetical protein compare
PfGW456L13_2113 +0.8 5.6 Transcriptional regulator, TetR family compare
PfGW456L13_3577 +0.8 1.0 hypothetical protein compare
PfGW456L13_1611 +0.8 1.6 FIG00954698: hypothetical protein compare
PfGW456L13_1795 +0.8 2.3 Aldehyde dehydrogenase (EC 1.2.1.3) compare
PfGW456L13_4354 +0.8 1.2 Flagellar hook-basal body complex protein FliE compare
PfGW456L13_591 +0.8 2.5 Cytochrome c4 compare
PfGW456L13_3671 +0.8 2.5 hypothetical protein compare
PfGW456L13_4925 +0.8 2.4 Probable glutathione S-transferase (EC 2.5.1.18), YfcF homolog compare
PfGW456L13_1599 +0.8 4.3 Hypoxanthine-guanine phosphoribosyltransferase (EC 2.4.2.8) compare
PfGW456L13_2603 +0.8 1.2 Transcriptional regulator, MarR family compare
PfGW456L13_584 +0.8 2.6 alginate biosynthesis transcriptional regulatory protein AlgB compare
PfGW456L13_4107 +0.8 3.5 CmpX compare
PfGW456L13_1630 +0.8 3.8 Butyryl-CoA dehydrogenase (EC 1.3.99.2) compare
PfGW456L13_2011 +0.8 2.5 Transcriptional regulatory protein PhoP compare
PfGW456L13_873 +0.8 4.1 Porphobilinogen synthase (EC 4.2.1.24) compare
PfGW456L13_1289 +0.8 2.4 Transcriptional regulator, AraC family compare
PfGW456L13_1864 +0.8 3.3 FIG023103: Predicted transmembrane protein compare
PfGW456L13_397 +0.8 3.1 Agmatine deiminase (EC 3.5.3.12) compare
PfGW456L13_2526 +0.8 2.0 4-hydroxyphenylacetate 3-monooxygenase, reductase component (EC 1.6.8.-) compare
PfGW456L13_481 +0.8 1.2 transcriptional regulator, Crp/Fnr family compare
PfGW456L13_1731 +0.8 1.5 NADH:flavin oxidoreductases, Old Yellow Enzyme family compare
PfGW456L13_1075 +0.8 4.8 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain compare
PfGW456L13_4068 +0.8 3.0 Type cbb3 cytochrome oxidase biogenesis protein CcoS, involved in heme b insertion compare
PfGW456L13_2638 +0.8 2.6 FIG002903: a protein of unknown function perhaps involved in purine metabolism compare
PfGW456L13_4008 +0.8 1.1 hypothetical protein compare
PfGW456L13_4743 +0.7 4.2 Outer membrane lipoprotein omp16 precursor compare
PfGW456L13_885 +0.7 3.0 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases / CDP-6-deoxy-delta-3,4-glucoseen reductase-like compare
PfGW456L13_898 +0.7 2.7 FIG00954652: hypothetical protein compare
PfGW456L13_3660 +0.7 2.8 Isochorismate pyruvate-lyase (EC 4.-.-.-) compare
PfGW456L13_2172 +0.7 4.9 S-adenosylhomocysteine deaminase (EC 3.5.4.28); Methylthioadenosine deaminase compare
PfGW456L13_932 +0.7 3.3 Putrescine transport system permease protein PotI (TC 3.A.1.11.2) compare
PfGW456L13_1977 +0.7 3.1 Succinylglutamate desuccinylase (EC 3.5.1.96) (from data) compare
PfGW456L13_1222 +0.7 3.2 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
PfGW456L13_5075 +0.7 3.4 Phosphoenolpyruvate-protein phosphotransferase of PTS system (EC 2.7.3.9) compare
PfGW456L13_4065 +0.7 5.2 Type cbb3 cytochrome oxidase biogenesis protein CcoG, involved in Cu oxidation compare
PfGW456L13_1862 +0.7 2.5 Queuosine Biosynthesis QueC ATPase compare
PfGW456L13_1696 +0.7 4.9 ATP-dependent RNA helicase RhlB compare
PfGW456L13_3989 +0.7 1.7 FIG00964275: hypothetical protein compare
PfGW456L13_3000 +0.7 0.7 FIG00961385: hypothetical protein compare
PfGW456L13_609 +0.7 3.6 Cytochrome oxidase biogenesis protein Surf1, facilitates heme A insertion compare
PfGW456L13_4031 +0.7 1.1 Beta N-acetyl-glucosaminidase (EC 3.2.1.52) compare
PfGW456L13_1634 +0.7 2.9 Ubiquinol-cytochrome C reductase iron-sulfur subunit (EC 1.10.2.2) compare
PfGW456L13_3210 +0.7 2.2 Enoyl-CoA hydratase (EC 4.2.1.17) compare
PfGW456L13_895 +0.7 1.5 FIG001590: Putative conserved exported protein precursor compare
PfGW456L13_4060 +0.7 4.7 hypothetical protein compare
PfGW456L13_752 +0.7 5.4 L-Proline/Glycine betaine transporter ProP compare
PfGW456L13_773 +0.7 2.8 Hydrogen peroxide-inducible genes activator compare
PfGW456L13_4865 +0.7 2.2 Ribosomal RNA large subunit methyltransferase N (EC 2.1.1.-) compare
PfGW456L13_1635 +0.7 4.5 Ubiquinol--cytochrome c reductase, cytochrome B subunit (EC 1.10.2.2) compare
PfGW456L13_3862 +0.7 1.2 DoxX family protein compare
PfGW456L13_1381 +0.7 2.5 FIG00955339: hypothetical protein compare
PfGW456L13_4127 +0.7 2.9 Hydantoin racemase (EC 5.1.99.-) compare
PfGW456L13_2686 +0.7 1.1 Glycine cleavage system H protein compare
PfGW456L13_4037 +0.7 2.2 FIG00953287: hypothetical protein compare
PfGW456L13_4576 +0.6 0.7 Transcriptional regulator, ArsR family compare
PfGW456L13_5151 +0.6 1.6 Exodeoxyribonuclease V beta chain (EC 3.1.11.5) compare
PfGW456L13_5056 +0.6 2.8 Dipeptide transport system permease protein DppC (TC 3.A.1.5.2) compare
PfGW456L13_3995 +0.6 3.3 UDP-N-acetylglucosamine 2-epimerase (EC 5.1.3.14) compare
PfGW456L13_3409 +0.6 1.3 Transcriptional regulator, IclR family compare
PfGW456L13_5123 +0.6 2.0 Ais protein, putative compare
PfGW456L13_1041 +0.6 1.0 Putative translation initiation inhibitor, yjgF family compare
PfGW456L13_4679 +0.6 1.9 tRNA pseudouridine 13 synthase (EC 4.2.1.-) compare
PfGW456L13_4745 +0.6 3.3 Hydrolase of the alpha/beta superfamily in cluster with COG2110 compare
PfGW456L13_2888 +0.6 3.5 Mobile element protein compare
PfGW456L13_194 +0.6 3.1 Cation transport ATPase compare
PfGW456L13_1536 +0.6 2.1 FOG: TPR repeat compare
PfGW456L13_3694 +0.6 1.5 Arsenical resistance operon repressor compare
PfGW456L13_765 +0.6 1.4 Chorismate--pyruvate lyase (EC 4.1.3.40) compare
PfGW456L13_2955 +0.6 1.4 RND efflux system, membrane fusion protein CmeA compare
PfGW456L13_792 +0.6 1.9 hypothetical protein compare
PfGW456L13_3830 +0.6 2.5 FIG00955248: hypothetical protein compare
PfGW456L13_249 +0.6 2.2 FIG085779: Lipoprotein compare
PfGW456L13_1604 +0.6 2.5 hypothetical protein compare
PfGW456L13_3771 +0.6 1.4 lipoprotein, putative compare
PfGW456L13_170 +0.6 4.1 Thiosulfate sulfurtransferase, rhodanese (EC 2.8.1.1) compare
PfGW456L13_3859 +0.6 1.4 Nicotinamidase family protein YcaC compare
PfGW456L13_152 +0.6 1.9 HflK protein compare
PfGW456L13_4069 +0.6 3.2 Heavy-metal-associated domain (N-terminus) and membrane-bounded cytochrome biogenesis cycZ-like domain, possible membrane copper tolerance protein compare
PfGW456L13_4972 +0.6 1.5 Hypothetical flavoprotein YqcA (clustered with tRNA pseudouridine synthase C) compare
PfGW456L13_1854 +0.6 1.3 4-hydroxybenzoyl-CoA thioesterase family active site compare
PfGW456L13_3125 +0.6 2.3 Glutathione-dependent formaldehyde-activating enzyme (EC 4.4.1.22) compare
PfGW456L13_97 +0.6 2.4 membrane protein, putative compare
PfGW456L13_2964 +0.6 2.6 CopG protein compare
PfGW456L13_4466 +0.6 2.0 hypothetical protein compare
PfGW456L13_1012 +0.6 1.8 Twitching motility protein PilT compare
PfGW456L13_1974 +0.6 2.1 Succinylglutamic semialdehyde dehydrogenase (EC 1.2.1.71) (from data) compare


Specific Phenotypes

For 18 genes in this experiment

For carbon source L-Tryptophan in Pseudomonas fluorescens GW456-L13

For carbon source L-Tryptophan across organisms