Experiment set1IT021 for Pseudomonas sp. S08-1

Compare to:

D,L-Malic Acid carbon source

200 most important genes:

  gene name fitness t score description  
OH686_14595 -3.7 -7.1 Imidazole glycerol phosphate synthase cyclase subunit compare
OH686_14100 -3.5 -16.5 dihydroxy-acid dehydratase compare
OH686_10005 -3.4 -24.8 Glutamate synthase [NADPH] large chain compare
OH686_13590 -3.4 -2.4 Orotate phosphoribosyltransferase compare
OH686_04480 -3.4 -11.8 3-isopropylmalate dehydratase large subunit compare
OH686_13545 -3.4 -12.1 RidA/YER057c/UK114 superfamily protein compare
OH686_13600 -3.3 -14.7 N-acetylglutamate kinase compare
OH686_13885 -3.3 -12.3 argininosuccinate lyase compare
OH686_04475 -3.3 -8.4 3-isopropylmalate dehydratase small subunit compare
OH686_12425 -3.2 -12.8 tryptophan synthase, beta subunit compare
OH686_10020 -3.1 -7.5 Shikimate kinase I compare
OH686_03475 -3.1 -6.3 Oxidoreductase putative compare
OH686_00475 -3.1 -15.4 Glycerol-3-phosphate dehydrogenase [NAD(P)+] compare
OH686_04470 -3.1 -16.7 3-isopropylmalate dehydrogenase compare
OH686_10000 -3.0 -16.8 Glutamate synthase [NADPH] small chain compare
OH686_08130 -3.0 -18.4 acetolactate synthase, large subunit, biosynthetic type compare
OH686_14580 -2.9 -13.8 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit compare
OH686_09445 -2.9 -14.0 ATP phosphoribosyltransferase, regulatory subunit compare
OH686_08125 -2.9 -13.8 acetolactate synthase, small subunit compare
OH686_13800 -2.9 -2.0 diaminopimelate decarboxylase compare
OH686_03930 -2.9 -15.0 argininosuccinate synthase compare
OH686_09555 -2.9 -14.0 phosphoserine phosphatase SerB compare
OH686_00285 -2.8 -13.9 Precorrin-2 oxidase or Sirohydrochlorin ferrochelatase activity of CysG / Uroporphyrinogen-III methyltransferase compare
OH686_08115 -2.8 -11.1 ketol-acid reductoisomerase compare
OH686_12485 -2.8 -5.3 Shikimate 5-dehydrogenase I alpha compare
OH686_11400 -2.8 -14.2 threonine ammonia-lyase, biosynthetic compare
OH686_12430 -2.8 -14.0 tryptophan synthase, alpha subunit compare
OH686_20870 -2.7 -4.9 Chorismate mutase I / Prephenate dehydratase compare
OH686_15195 -2.7 -9.4 N-acetyl-gamma-glutamyl-phosphate reductase compare
OH686_07585 -2.7 -6.4 3-dehydroquinate dehydratase, type II compare
OH686_11120 -2.6 -10.6 amino-acid N-acetyltransferase compare
OH686_17570 -2.6 -14.6 2-isopropylmalate synthase compare
OH686_21295 -2.6 -4.9 arginine/ornithine succinyltransferase, alpha subunit compare
OH686_17765 -2.6 -1.8 threonine synthase compare
OH686_08475 -2.6 -12.9 ATP phosphoribosyltransferase compare
OH686_03470 -2.6 -14.3 Sulfite reductase [NADPH] hemoprotein beta-component compare
OH686_15135 -2.5 -3.2 Anthranilate phosphoribosyltransferase compare
OH686_20405 -2.5 -9.0 ornithine carbamoyltransferase compare
OH686_14590 -2.5 -12.2 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase compare
OH686_08470 -2.5 -14.6 Histidinol dehydrogenase compare
OH686_10160 -2.5 -8.2 Phosphoribosyl-AMP cyclohydrolase compare
OH686_10820 -2.5 -13.6 methylenetetrahydrofolate reductase [NAD(P)H] compare
OH686_21330 -2.5 -2.7 aspartate kinase, monofunctional class compare
OH686_10980 -2.5 -3.7 pyrroline-5-carboxylate reductase compare
OH686_15125 -2.5 -14.4 anthranilate synthase component I compare
OH686_09710 -2.5 -3.7 pyruvate dehydrogenase (acetyl-transferring), homodimeric type compare
OH686_04445 -2.4 -12.5 Phosphoribosylanthranilate isomerase compare
OH686_15140 -2.4 -14.1 Indole-3-glycerol phosphate synthase compare
OH686_14435 -2.4 -17.3 Glycosyl transferase, group 1 family protein compare
OH686_11000 -2.3 -11.9 homoserine O-acetyltransferase compare
OH686_11285 -2.3 -14.8 D-2-hydroxyglutarate dehydrogenase compare
OH686_08495 -2.3 -2.2 Phospholipid ABC transporter shuttle protein MlaC compare
OH686_09340 -2.3 -7.3 Gamma-glutamyl phosphate reductase compare
OH686_14575 -2.3 -7.4 Imidazoleglycerol-phosphate dehydratase compare
OH686_02215 -2.3 -2.6 Putative analog of CcoH, COG3198 compare
OH686_08465 -2.3 -14.2 histidinol-phosphate transaminase compare
OH686_18180 -2.2 -2.1 Murein hydrolase activator NlpD compare
OH686_14390 -2.2 -14.3 UDP-N-acetyl-D-mannosamine dehydrogenase compare
OH686_16305 -2.2 -7.5 Glutamate 5-kinase / RNA-binding C-terminal domain PUA compare
OH686_04415 -2.2 -10.8 O-succinylhomoserine sulfhydrylase compare
OH686_11420 -2.2 -9.8 Phosphoserine phosphatase compare
OH686_08505 -2.2 -2.1 Phospholipid ABC transporter permease protein MlaE compare
OH686_20435 -2.2 -2.0 monothiol glutaredoxin, Grx4 family compare
OH686_20060 -2.1 -2.0 HtrA protease/chaperone protein compare
OH686_14385 -2.1 -13.9 UDP-N-acetylglucosamine 2-epimerase compare
OH686_12075 -2.1 -1.4 Exodeoxyribonuclease V beta chain compare
OH686_18990 -2.1 -2.4 phosphoribosylglycinamide formyltransferase compare
OH686_09860 -2.1 -2.4 Thioredoxin 2 compare
OH686_14355 -2.0 -7.6 C4-dicarboxylate transport transcriptional regulatory protein compare
OH686_22720 -2.0 -2.3 Outer-membrane-phospholipid-binding lipoprotein MlaA compare
OH686_20585 -1.9 -9.2 Na+/H+-dicarboxylate symporter compare
OH686_07640 -1.9 -2.2 probable sensor/response regulator hybrid compare
OH686_11005 -1.9 -8.3 methionine biosynthesis protein MetW compare
OH686_21570 -1.9 -2.8 Phage recombination protein NinG compare
OH686_12250 -1.9 -5.5 Zinc ABC transporter, permease protein ZnuB compare
OH686_21550 -1.9 -1.9 Origin specific replication binding factor compare
OH686_21965 -1.9 -2.4 Predicted transcriptional regulator for fatty acid degradation FadQ, TetR family compare
OH686_02190 -1.8 -4.2 cytochrome c oxidase, cbb3-type, subunit I compare
OH686_20895 -1.8 -2.9 integration host factor, beta subunit compare
OH686_13830 -1.8 -1.7 hypothetical protein compare
OH686_00140 -1.8 -4.0 NADH-ubiquinone oxidoreductase chain E compare
OH686_17760 -1.8 -2.4 Homoserine dehydrogenase compare
OH686_18175 -1.8 -5.1 protein-L-isoaspartate O-methyltransferase compare
OH686_08500 -1.8 -2.3 outer membrane lipid asymmetry maintenance protein MlaD compare
OH686_17100 -1.7 -2.0 Cell division-associated, ATP-dependent zinc metalloprotease FtsH compare
OH686_09625 -1.7 -7.6 hypothetical protein compare
OH686_12545 -1.7 -2.0 Lipid A biosynthesis lauroyl acyltransferase compare
OH686_02205 -1.7 -2.2 cytochrome c oxidase, cbb3-type, subunit III compare
OH686_08510 -1.7 -2.7 Phospholipid ABC transporter ATP-binding protein MlaF compare
OH686_00130 -1.7 -5.4 NADH dehydrogenase (quinone), G subunit compare
OH686_17260 -1.7 -6.2 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
OH686_00150 -1.7 -5.6 NADH-ubiquinone oxidoreductase chain B compare
OH686_14420 -1.7 -6.7 hypothetical protein compare
OH686_17470 -1.7 -2.9 iron-sulfur cluster assembly transcription factor IscR compare
OH686_09475 -1.6 -4.0 tRNA dimethylallyltransferase compare
OH686_09505 -1.6 -3.4 3'-to-5' oligoribonuclease (orn) compare
OH686_14360 -1.6 -8.0 Signal transduction histidine kinase regulating C4-dicarboxylate transport system compare
OH686_21945 -1.5 -6.4 hypothetical protein compare
OH686_22870 -1.5 -2.3 integration host factor, alpha subunit compare
OH686_16400 -1.5 -1.6 hypothetical protein compare
OH686_07905 -1.5 -2.3 protein-(glutamine-N5) methyltransferase, release factor-specific compare
OH686_10165 -1.4 -4.5 Phosphoribosyl-ATP pyrophosphatase compare
OH686_11110 -1.4 -4.2 glutamate--cysteine ligase compare
OH686_14285 -1.4 -9.2 Thiazole synthase compare
OH686_14835 -1.4 -2.2 CDS compare
OH686_12130 -1.4 -1.8 UPF0391 membrane protein YtjA compare
OH686_00095 -1.4 -6.2 NADH-ubiquinone oxidoreductase chain N compare
OH686_00145 -1.3 -6.2 NADH-ubiquinone oxidoreductase chain C / NADH-ubiquinone oxidoreductase chain D compare
OH686_20815 -1.3 -1.6 hypothetical protein compare
OH686_12235 -1.3 -2.8 Zinc ABC transporter, substrate-binding protein ZnuA compare
OH686_21290 -1.3 -5.3 Succinylornithine transaminase compare
OH686_00105 -1.3 -5.0 NADH-ubiquinone oxidoreductase chain L compare
OH686_11275 -1.3 -5.0 Exopolyphosphatase compare
OH686_04115 -1.3 -1.6 hypothetical protein compare
OH686_21970 -1.3 -3.5 L,D-transpeptidase compare
OH686_11280 -1.3 -3.4 D-3-phosphoglycerate dehydrogenase compare
OH686_09560 -1.3 -2.0 HAMP domain protein compare
OH686_00155 -1.2 -3.4 NADH ubiquinone oxidoreductase chain A compare
OH686_00115 -1.2 -1.6 NADH-ubiquinone oxidoreductase chain J compare
OH686_00695 -1.2 -3.4 2,3-diketo-5-methylthio-1-phosphopentane phosphatase compare
OH686_11060 -1.2 -4.5 phosphoenolpyruvate carboxykinase (ATP) compare
OH686_12080 -1.2 -3.5 exodeoxyribonuclease V, gamma subunit compare
OH686_13550 -1.2 -1.7 Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase / GTP pyrophosphokinase , (p)ppGpp synthetase II compare
OH686_08245 -1.2 -4.5 glutamate N-acetyltransferase/amino-acid acetyltransferase compare
OH686_13425 -1.2 -6.2 phosphate ABC transporter, ATP-binding protein compare
OH686_00125 -1.2 -2.5 NADH-ubiquinone oxidoreductase chain H compare
OH686_19125 -1.2 -4.3 crossover junction endodeoxyribonuclease RuvC compare
OH686_00135 -1.2 -3.7 NADH oxidoreductase (quinone), F subunit compare
OH686_14425 -1.2 -8.4 glycosyl transferase, group 1 family protein compare
OH686_01680 -1.1 -3.2 2-methylisocitrate dehydratase, Fe/S-dependent compare
OH686_17740 -1.1 -1.8 ribosomal protein L19 compare
OH686_12195 -1.1 -2.6 Periplasmic thiol:disulfide interchange protein DsbA compare
OH686_08525 -1.1 -2.0 LPS export ABC transporter periplasmic protein LptC compare
OH686_14280 -1.1 -6.3 thiamine biosynthesis protein ThiS compare
OH686_18170 -1.1 -3.7 5'/3'-nucleotidase SurE compare
OH686_01730 -1.1 -6.4 Cys regulon transcriptional activator CysB compare
OH686_01780 -1.1 -5.8 L,D-transpeptidase compare
OH686_21300 -1.1 -4.4 arginine N-succinyltransferase compare
OH686_07900 -1.1 -5.0 Molybdopterin-synthase adenylyltransferase compare
OH686_17405 -1.1 -2.1 Predicted transmembrane protein compare
OH686_09190 -1.1 -5.9 Thiamin-phosphate pyrophosphorylase compare
OH686_04185 -1.0 -1.5 Bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) compare
OH686_09185 -1.0 -6.4 Hydroxymethylpyrimidine phosphate kinase ThiD compare
OH686_19770 -1.0 -3.0 septum site-determining protein MinD compare
OH686_18760 -1.0 -2.5 D-erythro-7,8-dihydroneopterin triphosphate epimerase compare
OH686_22150 -1.0 -3.2 beta-ketoacyl-acyl-carrier-protein synthase II compare
OH686_04550 -1.0 -1.5 tRNA-Ala compare
OH686_11225 -1.0 -6.0 5-formyltetrahydrofolate cyclo-ligase compare
OH686_00120 -1.0 -2.2 NADH-ubiquinone oxidoreductase chain I compare
OH686_19135 -1.0 -4.4 Holliday junction DNA helicase RuvB compare
OH686_19980 -1.0 -1.6 Ammonia monooxygenase compare
OH686_18240 -1.0 -2.0 Two-component transcriptional response regulator, LuxR family compare
OH686_14145 -1.0 -1.0 Uncharacterized ferredoxin-like protein YfhL compare
OH686_21585 -1.0 -4.1 hypothetical protein compare
OH686_13415 -1.0 -6.6 Phosphate ABC transporter, permease protein PstC compare
OH686_05085 -1.0 -6.7 precorrin-6A synthase (deacetylating) compare
OH686_04045 -1.0 -1.3 hypothetical protein compare
OH686_05545 -0.9 -1.1 hypothetical protein compare
OH686_13410 -0.9 -6.8 Phosphate ABC transporter, substrate-binding protein PstS compare
OH686_09055 -0.9 -1.7 Transcriptional regulator, AcrR family compare
OH686_04340 -0.9 -1.4 tRNA-Asp compare
OH686_03640 -0.9 -1.5 ATP-dependent Clp protease, ATP-binding subunit ClpX compare
OH686_19540 -0.9 -1.3 hypothetical protein compare
OH686_19190 -0.9 -6.4 quinolinate synthetase complex, A subunit compare
OH686_01625 -0.9 -1.8 Nonspecific porin and structural outer membrane protein OprF compare
OH686_00100 -0.9 -3.3 NADH-ubiquinone oxidoreductase chain M compare
OH686_00845 -0.9 -3.3 Methylglutaconyl-CoA hydratase compare
OH686_03635 -0.9 -5.0 endopeptidase La compare
OH686_14415 -0.9 -5.2 Adenylylsulfate kinase compare
OH686_16520 -0.8 -5.7 nicotinate-nucleotide diphosphorylase (carboxylating) compare
OH686_15625 -0.8 -4.6 dTDP-4-dehydrorhamnose reductase compare
OH686_21350 -0.8 -1.7 tRNA-Arg compare
OH686_17465 -0.8 -2.5 serine O-acetyltransferase compare
OH686_09470 -0.8 -1.1 RNA chaperone Hfq compare
OH686_17820 -0.8 -1.0 Amino acid ABC transporter, ATP-binding protein YhdZ compare
OH686_10060 -0.8 -5.4 NADP-dependent malic enzyme compare
OH686_19335 -0.8 -1.8 hypothetical protein compare
OH686_10235 -0.8 -1.2 hypothetical protein compare
OH686_15870 -0.8 -2.7 hypothetical protein compare
OH686_07035 -0.8 -1.6 hypothetical protein compare
OH686_10905 -0.8 -2.7 twitching motility protein PilH compare
OH686_13460 -0.8 -4.0 phosphate regulon sensor kinase PhoR compare
OH686_23190 -0.8 -0.9 hypothetical protein compare
OH686_22050 -0.8 -1.5 MotA/TolQ/ExbB proton channel family protein compare
OH686_07395 -0.8 -4.5 copper-translocating P-type ATPase compare
OH686_09620 -0.8 -4.2 Serine acetyltransferase compare
OH686_10190 -0.7 -2.7 hypothetical protein compare
OH686_05835 -0.7 -1.4 Transcriptional regulator, MarR family compare
OH686_23130 -0.7 -1.4 2-hydroxymuconate tautomerase-like protein compare
OH686_10030 -0.7 -3.2 CDS compare
OH686_10025 -0.7 -4.5 Type IV pilus biogenesis protein PilQ compare
OH686_08255 -0.7 -1.4 hypothetical protein compare
OH686_07610 -0.7 -2.7 tRNA-dihydrouridine synthase DusB compare
OH686_02020 -0.7 -2.0 Inhibitor of the KinA pathway to sporulation, predicted exonuclease compare
OH686_18680 -0.7 -2.4 peroxiredoxin compare
OH686_08565 -0.7 -0.7 Phosphocarrier protein, nitrogen regulation associated compare
OH686_18290 -0.7 -1.5 transcriptional regulator MvaT, P16 subunit compare
OH686_05075 -0.7 -2.7 ChlI component of cobalt chelatase compare
OH686_12215 -0.7 -5.3 DNA polymerase I compare
OH686_15690 -0.7 -2.2 transcriptional regulator NrdR compare


Specific Phenotypes

None in this experiment

For Pseudomonas sp. S08-1 in carbon source experiments

For carbon source D,L-Malic Acid across organisms