Experiment set1IT014 for Pseudomonas fluorescens GW456-L13

Compare to:

Glycerol carbon source

200 most important genes:

  gene name fitness t score description  
PfGW456L13_362 -6.6 -4.6 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
PfGW456L13_302 -6.4 -4.4 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
PfGW456L13_172 -6.3 -6.2 Phosphoserine phosphatase (EC 3.1.3.3) compare
PfGW456L13_3934 -6.3 -8.6 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
PfGW456L13_1007 -6.2 -4.3 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
PfGW456L13_1472 -6.2 -4.3 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA compare
PfGW456L13_3948 -6.1 -4.2 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
PfGW456L13_3940 -6.1 -4.2 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
PfGW456L13_1222 -6.1 -4.2 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
PfGW456L13_973 -6.1 -9.3 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
PfGW456L13_3947 -6.1 -4.2 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
PfGW456L13_1010 -6.0 -4.2 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) compare
PfGW456L13_361 -6.0 -11.5 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
PfGW456L13_303 -5.9 -3.2 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
PfGW456L13_5001 -5.9 -4.1 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
PfGW456L13_358 -5.9 -2.7 Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) compare
PfGW456L13_359 -5.8 -7.0 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
PfGW456L13_3945 -5.8 -4.0 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
PfGW456L13_1540 -5.8 -5.7 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
PfGW456L13_2842 -5.7 -5.5 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
PfGW456L13_1539 -5.7 -5.5 Acetolactate synthase small subunit (EC 2.2.1.6) compare
PfGW456L13_149 -5.5 -7.6 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
PfGW456L13_727 -5.5 -9.9 LysR family transcriptional regulator PA5437 compare
PfGW456L13_913 -5.5 -3.8 N-acetylglutamate synthase (EC 2.3.1.1) compare
PfGW456L13_728 -5.4 -13.5 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
PfGW456L13_5000 -5.4 -15.6 Histidinol dehydrogenase (EC 1.1.1.23) compare
PfGW456L13_845 -5.3 -3.7 Diaminopimelate decarboxylase (EC 4.1.1.20) compare
PfGW456L13_951 -5.3 -13.7 Phosphoserine phosphatase (EC 3.1.3.3) compare
PfGW456L13_644 -5.3 -9.2 Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) compare
PfGW456L13_1221 -5.2 -14.2 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
PfGW456L13_1739 -5.0 -9.0 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
PfGW456L13_2623 -5.0 -3.0 NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3) compare
PfGW456L13_4125 -5.0 -3.0 Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10) compare
PfGW456L13_1233 -5.0 -3.4 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) compare
PfGW456L13_150 -5.0 -2.2 hypothetical protein compare
PfGW456L13_2230 -4.9 -9.4 Cys regulon transcriptional activator CysB compare
PfGW456L13_1368 -4.9 -6.7 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
PfGW456L13_1217 -4.9 -18.2 Anthranilate synthase, aminase component (EC 4.1.3.27) compare
PfGW456L13_2032 -4.9 -4.7 Cysteine synthase B (EC 2.5.1.47) compare
PfGW456L13_1050 -4.8 -9.8 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
PfGW456L13_2176 -4.8 -8.1 Chorismate mutase I (EC 5.4.99.5) / Prephenate dehydratase (EC 4.2.1.51) compare
PfGW456L13_4088 -4.7 -3.7 Transcriptional regulator, GntR family compare
PfGW456L13_1147 -4.6 -15.0 Biotin synthase (EC 2.8.1.6) compare
PfGW456L13_729 -4.5 -13.7 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
PfGW456L13_1151 -4.5 -10.9 Dethiobiotin synthetase (EC 6.3.3.3) compare
PfGW456L13_1538 -4.5 -13.5 Acetolactate synthase large subunit (EC 2.2.1.6) compare
PfGW456L13_3960 -4.4 -11.1 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
PfGW456L13_1524 -4.4 -7.8 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
PfGW456L13_565 -4.3 -5.9 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
PfGW456L13_1749 -4.3 -3.0 Argininosuccinate synthase (EC 6.3.4.5) compare
PfGW456L13_854 -4.2 -2.9 Argininosuccinate lyase (EC 4.3.2.1) compare
PfGW456L13_5067 -4.2 -12.7 Ornithine decarboxylase (EC 4.1.1.17) / Arginine decarboxylase (EC 4.1.1.19) compare
PfGW456L13_2656 -4.2 -9.5 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
PfGW456L13_1148 -4.0 -17.3 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
PfGW456L13_4854 -4.0 -10.3 2-isopropylmalate synthase (EC 2.3.3.13) compare
PfGW456L13_2843 -4.0 -9.1 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
PfGW456L13_4859 -4.0 -2.8 Outer membrane protein YfgL, lipoprotein component of the protein assembly complex (forms a complex with YaeT, YfiO, and NlpB) compare
PfGW456L13_3472 -4.0 -3.1 Bll0377 protein compare
PfGW456L13_566 -3.9 -8.8 Tryptophan synthase beta chain (EC 4.2.1.20) compare
PfGW456L13_1044 -3.9 -11.3 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
PfGW456L13_2552 -3.8 -8.4 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
PfGW456L13_1615 -3.8 -1.9 Probable transmembrane protein compare
PfGW456L13_1150 -3.8 -16.0 Biotin synthesis protein BioC compare
PfGW456L13_943 -3.7 -7.3 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
PfGW456L13_793 -3.6 -3.8 Acetylglutamate kinase (EC 2.7.2.8) compare
PfGW456L13_5008 -3.5 -2.1 Uncharacterized ABC transporter, ATP-binding protein YrbF compare
PfGW456L13_5082 -3.5 -7.3 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
PfGW456L13_275 -3.5 -2.3 3-dehydroquinate synthase (EC 4.2.3.4) compare
PfGW456L13_4165 -3.5 -4.4 Chorismate synthase (EC 4.2.3.5) compare
PfGW456L13_276 -3.5 -1.3 Shikimate kinase I (EC 2.7.1.71) compare
PfGW456L13_1006 -3.4 -4.4 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
PfGW456L13_1845 -3.3 -4.5 Cold shock protein CspC compare
PfGW456L13_1220 -3.3 -4.8 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
PfGW456L13_1363 -3.3 -8.0 Rare lipoprotein A precursor compare
PfGW456L13_1735 -3.3 -3.2 Glycerol uptake facilitator protein compare
PfGW456L13_5006 -3.2 -3.1 Uncharacterized ABC transporter, periplasmic component YrbD compare
PfGW456L13_2651 -3.2 -5.8 Cell division protein FtsK compare
PfGW456L13_757 -3.2 -2.3 Phosphate transport system regulatory protein PhoU compare
PfGW456L13_953 -3.2 -12.3 FIG001592: Phosphocarrier protein kinase/phosphorylase, nitrogen regulation associated compare
PfGW456L13_2941 -3.2 -1.8 Glycerate kinase (EC 2.7.1.31) compare
PfGW456L13_4253 -3.1 -3.7 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
PfGW456L13_5005 -3.0 -3.6 Uncharacterized ABC transporter, auxiliary component YrbC compare
PfGW456L13_4041 -2.9 -3.0 Enoyl-CoA hydratase (EC 4.2.1.17) / Delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase (EC 5.3.3.8) / 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) / 3-hydroxybutyryl-CoA epimerase (EC 5.1.2.3) compare
PfGW456L13_2159 -2.9 -2.1 hypothetical protein compare
PfGW456L13_3894 -2.9 -1.8 Integration host factor alpha subunit compare
PfGW456L13_3755 -2.8 -2.9 Amidase (EC 3.5.1.4) compare
PfGW456L13_4254 -2.8 -6.9 FIG00955360: hypothetical protein compare
PfGW456L13_1972 -2.8 -2.6 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
PfGW456L13_952 -2.8 -5.9 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
PfGW456L13_5150 -2.7 -3.3 Exodeoxyribonuclease V alpha chain (EC 3.1.11.5) compare
PfGW456L13_1498 -2.7 -1.9 FIG060329: MOSC domain protein compare
PfGW456L13_5048 -2.7 -3.1 Dna binding response regulator PrrA (RegA) compare
PfGW456L13_1655 -2.6 -1.8 D-alanine--D-alanine ligase (EC 6.3.2.4) compare
PfGW456L13_1852 -2.6 -6.9 Holliday junction DNA helicase RuvA compare
PfGW456L13_1838 -2.6 -6.8 Sensory box histidine kinase compare
PfGW456L13_1574 -2.6 -4.3 GTP-binding and nucleic acid-binding protein YchF compare
PfGW456L13_779 -2.6 -10.2 Bona fide RidA/YjgF/TdcF/RutC subgroup compare
PfGW456L13_1863 -2.6 -7.4 Quinolinate synthetase (EC 2.5.1.72) compare
PfGW456L13_2237 -2.5 -2.8 Organic hydroperoxide resistance transcriptional regulator compare
PfGW456L13_2597 -2.5 -6.9 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) compare
PfGW456L13_874 -2.5 -15.6 Polyphosphate kinase (EC 2.7.4.1) compare
PfGW456L13_2553 -2.4 -8.3 ATP-dependent Clp protease ATP-binding subunit ClpX compare
PfGW456L13_756 -2.4 -6.3 Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1) compare
PfGW456L13_2800 -2.4 -1.9 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system compare
PfGW456L13_2551 -2.4 -3.1 Cell division trigger factor (EC 5.2.1.8) compare
PfGW456L13_5118 -2.3 -10.5 D-lactate dehydrogenase (quinone), FeS subunit (EC 1.1.5.12) (from data) conserved
PfGW456L13_296 -2.3 -2.5 Polyhydroxyalkanoate granule-associated protein PhaF compare
PfGW456L13_4009 -2.3 -9.8 Transaldolase (EC 2.2.1.2) compare
PfGW456L13_50 -2.3 -6.2 3-dehydroquinate dehydratase II (EC 4.2.1.10) compare
PfGW456L13_1981 -2.3 -6.3 Aspartokinase (EC 2.7.2.4) compare
PfGW456L13_4671 -2.2 -7.6 Transcriptional regulator, Cro/CI family compare
PfGW456L13_3179 -2.2 -4.2 Organic hydroperoxide resistance transcriptional regulator compare
PfGW456L13_3052 -2.2 -1.9 Response regulator compare
PfGW456L13_656 -2.2 -3.4 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
PfGW456L13_3835 -2.2 -3.0 FIG00957304: hypothetical protein compare
PfGW456L13_151 -2.1 -4.6 HflC protein compare
PfGW456L13_1580 -2.1 -6.7 FIG140336: TPR domain protein compare
PfGW456L13_4207 -2.1 -5.9 Periplasmic protease compare
PfGW456L13_2436 -2.1 -4.2 Phenylacetic acid degradation operon negative regulatory protein PaaX compare
PfGW456L13_1984 -2.1 -2.3 Mg/Co/Ni transporter MgtE / CBS domain compare
PfGW456L13_247 -2.1 -2.4 FIG022199: FAD-binding protein compare
PfGW456L13_2084 -2.1 -2.2 MotA/TolQ/ExbB proton channel family protein compare
PfGW456L13_3398 -2.0 -4.5 Transcriptional regulator, TetR family compare
PfGW456L13_718 -2.0 -2.6 Pyridoxal kinase (EC 2.7.1.35) compare
PfGW456L13_1734 -2.0 -8.1 Glycerol kinase (EC 2.7.1.30) compare
PfGW456L13_1370 -2.0 -3.4 FIG00957593: hypothetical protein compare
PfGW456L13_1889 -2.0 -3.6 Phosphogluconate dehydratase (EC 4.2.1.12) compare
PfGW456L13_1205 -2.0 -6.5 Glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) compare
PfGW456L13_140 -1.9 -3.5 FIG003573: hypothetical protein compare
PfGW456L13_5018 -1.9 -5.3 Phosphocarrier protein, nitrogen regulation associated compare
PfGW456L13_420 -1.9 -1.3 Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49) compare
PfGW456L13_2632 -1.9 -2.9 NADH-ubiquinone oxidoreductase chain B (EC 1.6.5.3) compare
PfGW456L13_3683 -1.9 -2.4 FIG00957787: hypothetical protein compare
PfGW456L13_2035 -1.8 -8.3 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) compare
PfGW456L13_4842 -1.8 -2.9 Translation elongation factor LepA compare
PfGW456L13_62 -1.8 -1.1 hypothetical protein compare
PfGW456L13_4015 -1.8 -3.7 NADPH dependent preQ0 reductase (EC 1.7.1.13) compare
PfGW456L13_2483 -1.8 -7.6 Permease of the drug/metabolite transporter (DMT) superfamily compare
PfGW456L13_144 -1.8 -4.8 3'-to-5' exoribonuclease RNase R compare
PfGW456L13_1219 -1.8 -1.9 hypothetical protein compare
PfGW456L13_3936 -1.8 -4.3 Colicin V production protein compare
PfGW456L13_2556 -1.7 -1.6 Peptidyl-prolyl cis-trans isomerase PpiD (EC 5.2.1.8) compare
PfGW456L13_355 -1.7 -3.7 Carboxyl-terminal protease (EC 3.4.21.102) compare
PfGW456L13_4999 -1.7 -8.5 Histidinol-phosphate aminotransferase (EC 2.6.1.9) compare
PfGW456L13_4574 -1.7 -2.4 1-acyl-sn-glycerol-3-phosphate acyltransferase (EC 2.3.1.51) compare
PfGW456L13_1160 -1.7 -5.1 Putative DNA-binding protein in cluster with Type I restriction-modification system compare
PfGW456L13_2826 -1.7 -1.2 hypothetical protein compare
PfGW456L13_1603 -1.7 -1.7 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
PfGW456L13_4365 -1.7 -3.0 3-oxoacyl-[acyl-carrier-protein] synthase, KASIII (EC 2.3.1.180) compare
PfGW456L13_784 -1.7 -5.5 Ribonuclease PH (EC 2.7.7.56) compare
PfGW456L13_2631 -1.7 -2.7 NADH-ubiquinone oxidoreductase chain C (EC 1.6.5.3) / NADH-ubiquinone oxidoreductase chain D (EC 1.6.5.3) compare
PfGW456L13_766 -1.7 -1.2 hypothetical protein compare
PfGW456L13_1936 -1.7 -1.5 RNA polymerase sigma-70 factor, ECF subfamily compare
PfGW456L13_1973 -1.7 -4.5 Arginine N-succinyltransferase (EC 2.3.1.109) compare
PfGW456L13_1153 -1.7 -7.9 Acyl-CoA dehydrogenase (EC 1.3.8.7) compare
PfGW456L13_5046 -1.6 -5.4 Predicted D-glucarate or D-galactorate regulator, GntR family compare
PfGW456L13_556 -1.6 -1.3 NAD(P) transhydrogenase alpha subunit (EC 1.6.1.2) compare
PfGW456L13_3445 -1.6 -2.3 hypothetical protein compare
PfGW456L13_1528 -1.6 -1.9 C4-type zinc finger protein, DksA/TraR family compare
PfGW456L13_949 -1.6 -7.4 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
PfGW456L13_236 -1.6 -1.9 Acyl carrier protein (ACP1) compare
PfGW456L13_1351 -1.6 -7.4 LrgA-associated membrane protein LrgB conserved
PfGW456L13_5086 -1.5 -3.2 tRNA pseudouridine synthase B (EC 4.2.1.70) compare
PfGW456L13_4170 -1.5 -3.1 Isochorismatase (EC 3.3.2.1) compare
PfGW456L13_1813 -1.5 -5.9 Pyruvate kinase (EC 2.7.1.40) compare
PfGW456L13_3433 -1.5 -1.8 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100) compare
PfGW456L13_3107 -1.5 -2.3 Type I restriction-modification system, specificity subunit S (EC 3.1.21.3) compare
PfGW456L13_2933 -1.5 -3.0 LysR family transcriptional regulator STM2281 compare
PfGW456L13_753 -1.5 -7.5 Phosphate ABC transporter, periplasmic phosphate-binding protein PstS (TC 3.A.1.7.1) compare
PfGW456L13_4477 -1.5 -2.4 Allophanate hydrolase 2 subunit 1 (EC 3.5.1.54) compare
PfGW456L13_2803 -1.5 -5.9 Glyceraldehyde-3-phosphate dehydrogenase, putative conserved
PfGW456L13_3718 -1.5 -2.6 Dihydrofolate reductase (EC 1.5.1.3) compare
PfGW456L13_4451 -1.5 -4.9 ATP-dependent RNA helicase SrmB compare
PfGW456L13_1067 -1.5 -2.2 FIG00955006: hypothetical protein compare
PfGW456L13_4071 -1.5 -2.9 Fumarate and nitrate reduction regulatory protein compare
PfGW456L13_274 -1.5 -7.0 DamX, an inner membrane protein involved in bile resistance compare
PfGW456L13_1738 -1.5 -2.5 Ferric iron ABC transporter, ATP-binding protein compare
PfGW456L13_2955 -1.5 -1.5 RND efflux system, membrane fusion protein CmeA compare
PfGW456L13_4711 -1.4 -8.8 [Protein-PII] uridylyltransferase (EC 2.7.7.59) compare
PfGW456L13_5022 -1.4 -3.6 Fumarate hydratase class II (EC 4.2.1.2) compare
PfGW456L13_581 -1.4 -1.4 hypothetical protein compare
PfGW456L13_1525 -1.4 -6.5 Two-component sensor CbrA: intrcellular carbon:nitrogen balance compare
PfGW456L13_4595 -1.4 -3.0 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
PfGW456L13_434 -1.4 -2.9 Alpha-ketoglutarate-dependent taurine dioxygenase (EC 1.14.11.17) compare
PfGW456L13_1523 -1.4 -2.3 Poly(A) polymerase (EC 2.7.7.19) compare
PfGW456L13_2164 -1.4 -1.9 Thioredoxin compare
PfGW456L13_3525 -1.4 -1.7 ABC transporter, ATP-binding protein compare
PfGW456L13_1888 -1.4 -7.3 NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) compare
PfGW456L13_2221 -1.4 -6.6 ErfK/YbiS/YcfS/YnhG family protein compare
PfGW456L13_4402 -1.4 -2.2 Segregation and condensation protein B compare
PfGW456L13_4641 -1.4 -1.7 Deoxycytidine triphosphate deaminase (EC 3.5.4.13) compare
PfGW456L13_350 -1.4 -2.6 Protein export cytoplasm chaperone protein (SecB, maintains protein to be exported in unfolded state) compare
PfGW456L13_59 -1.4 -4.4 Sensor histidine kinase/response regulator compare
PfGW456L13_2297 -1.4 -3.0 Cytochrome c-type biogenesis protein CcmG/DsbE, thiol:disulfide oxidoreductase compare
PfGW456L13_773 -1.4 -3.0 Hydrogen peroxide-inducible genes activator compare
PfGW456L13_5089 -1.4 -1.2 Transcription termination protein NusA compare
PfGW456L13_139 -1.3 -1.3 LSU ribosomal protein L9p compare
PfGW456L13_3610 -1.3 -1.4 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100) compare
PfGW456L13_4517 -1.3 -7.2 L-aspartate oxidase (EC 1.4.3.16) compare
PfGW456L13_4012 -1.3 -1.3 VacJ-like lipoprotein precursor compare


Specific Phenotypes

For 6 genes in this experiment

For carbon source Glycerol in Pseudomonas fluorescens GW456-L13

For carbon source Glycerol across organisms