Experiment set1IT007 for Pseudomonas sp. RS175

Compare to:

L-Hydroxyproline carbon 10 mM

200 most important genes:

  gene name fitness t score description  
PFR28_04933 -6.7 -4.2 Imidazole glycerol phosphate synthase subunit HisF compare
PFR28_04932 -6.0 -5.8 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase compare
PFR28_04278 -6.0 -10.0 Dihydroxy-acid dehydratase compare
PFR28_03714 -5.9 -18.1 RNA polymerase-binding transcription factor DksA compare
PFR28_04985 -5.8 -4.0 Phosphoribosyl-ATP pyrophosphatase compare
PFR28_01783 -5.4 -10.4 HTH-type transcriptional activator RhaS conserved
PFR28_04071 -5.3 -1.8 Multifunctional CCA protein compare
PFR28_03227 -5.3 -12.8 Signal transduction histidine-protein kinase BarA compare
PFR28_05125 -5.3 -10.1 ATP phosphoribosyltransferase regulatory subunit compare
PFR28_01782 -5.2 -16.6 Membrane-bound lytic murein transglycosylase F compare
PFR28_01787 -5.2 -10.2 4-hydroxyproline 2-epimerase conserved
PFR28_00187 -5.0 -16.0 Histidinol dehydrogenase compare
PFR28_02823 -5.0 -2.8 3-isopropylmalate dehydratase small subunit 1 compare
PFR28_01786 -4.9 -6.7 Hydrogen cyanide synthase subunit HcnC compare
PFR28_01930 -4.9 -3.4 HTH-type transcriptional regulator McbR compare
PFR28_03697 -4.9 -17.3 Ketol-acid reductoisomerase (NADP(+)) compare
PFR28_04245 -4.9 -17.7 Homoserine O-succinyltransferase compare
PFR28_00186 -4.8 -7.3 ATP phosphoribosyltransferase compare
PFR28_00305 -4.8 -13.6 2-isopropylmalate synthase compare
PFR28_04834 -4.7 -19.4 L-threonine dehydratase biosynthetic IlvA compare
PFR28_05015 -4.7 -27.9 Glutamate synthase [NADPH] large chain compare
PFR28_03698 -4.7 -9.9 Acetolactate synthase isozyme 3 small subunit compare
PFR28_02821 -4.6 -20.8 3-isopropylmalate dehydrogenase compare
PFR28_01410 -4.5 -9.9 Response regulator GacA compare
PFR28_05105 -4.5 -11.3 Phosphoserine phosphatase SerB2 compare
PFR28_01784 -4.4 -9.4 Hydrogen cyanide synthase subunit HcnB compare
PFR28_01780 -4.4 -9.4 Octopine transport system permease protein OccM compare
PFR28_00403 -4.4 -5.2 Regulator of sigma-E protease RseP compare
PFR28_04308 -4.4 -3.0 Amino-acid acetyltransferase compare
PFR28_05053 -4.4 -20.5 Bifunctional protein PutA conserved
PFR28_04202 -4.4 -3.0 5,10-methylenetetrahydrofolate reductase compare
PFR28_03363 -4.3 -19.6 Ornithine carbamoyltransferase 1, anabolic compare
PFR28_02810 -4.3 -15.0 O-succinylhomoserine sulfhydrylase compare
PFR28_04246 -4.2 -11.7 Bifunctional methionine biosynthesis protein MetXA/MetW compare
PFR28_00194 -4.2 -12.2 Bifunctional enzyme CysN/CysC compare
PFR28_00303 -4.1 -12.8 Omega-amidase YafV compare
PFR28_04565 -4.1 -16.6 Protein RarD compare
PFR28_03217 -4.1 -2.8 Phosphoribosylformylglycinamidine cyclo-ligase compare
PFR28_04930 -4.1 -11.2 Imidazole glycerol phosphate synthase subunit HisH compare
PFR28_02824 -4.1 -6.5 3-isopropylmalate dehydratase large subunit compare
PFR28_05016 -4.0 -14.8 Glutamate synthase [NADPH] small chain compare
PFR28_01777 -4.0 -1.9 putative trans-3-hydroxy-L-proline dehydratase compare
PFR28_03282 -3.9 -9.4 Arginine N-succinyltransferase subunit alpha compare
PFR28_00089 -3.9 -1.7 Transcription termination/antitermination protein NusA compare
PFR28_01778 -3.8 -5.8 Glutamine transport ATP-binding protein GlnQ compare
PFR28_03860 -3.8 -5.5 putative murein peptide carboxypeptidase compare
PFR28_01779 -3.7 -8.2 Arginine transport system permease protein ArtQ compare
PFR28_04986 -3.7 -8.2 Phosphoribosyl-AMP cyclohydrolase compare
PFR28_03281 -3.6 -5.8 Arginine N-succinyltransferase subunit beta compare
PFR28_03699 -3.6 -10.1 Acetolactate synthase isozyme 3 large subunit compare
PFR28_01366 -3.5 -12.8 Sulfite reductase [ferredoxin] compare
PFR28_01776 -3.5 -7.0 4-hydroxy-tetrahydrodipicolinate synthase compare
PFR28_03718 -3.5 -5.8 Transcriptional regulatory protein ZraR compare
PFR28_04564 -3.5 -13.3 Aspartate-semialdehyde dehydrogenase compare
PFR28_02811 -3.5 -8.5 Amidophosphoribosyltransferase compare
PFR28_00193 -3.4 -11.0 Sulfate adenylyltransferase subunit 2 compare
PFR28_03388 -3.3 -12.7 Quinolinate synthase A compare
PFR28_04566 -3.3 -11.1 4-chloro-allylglycine synthase compare
PFR28_04929 -3.3 -6.2 Histidine biosynthesis bifunctional protein HisB compare
PFR28_04569 -3.2 -7.9 HTH-type transcriptional regulator CdhR compare
PFR28_01114 -3.2 -6.0 hypothetical protein compare
PFR28_02603 -3.2 -7.6 Siroheme synthase compare
PFR28_00188 -3.1 -11.1 Histidinol-phosphate aminotransferase compare
PFR28_04064 -3.1 -5.1 Ribosomal RNA small subunit methyltransferase A compare
PFR28_00098 -3.1 -10.1 Nicotinate-nucleotide pyrophosphorylase [carboxylating] compare
PFR28_04831 -3.1 -4.1 RNA pyrophosphohydrolase compare
PFR28_04958 -3.1 -2.6 hypothetical protein compare
PFR28_04567 -3.0 -13.0 hypothetical protein compare
PFR28_04755 -3.0 -12.4 Glutarate-semialdehyde dehydrogenase compare
PFR28_01365 -3.0 -5.3 hypothetical protein compare
PFR28_04436 -2.9 -9.4 hypothetical protein compare
PFR28_00837 -2.9 -6.9 hypothetical protein compare
PFR28_04832 -2.8 -10.4 putative phosphatase compare
PFR28_03218 -2.8 -5.9 Phosphoribosylglycinamide formyltransferase compare
PFR28_04842 -2.7 -5.3 D-3-phosphoglycerate dehydrogenase compare
PFR28_03223 -2.7 -12.7 GTP pyrophosphokinase compare
PFR28_00689 -2.7 -13.3 L-aspartate oxidase compare
PFR28_03273 -2.6 -3.9 Aspartate kinase compare
PFR28_05120 -2.6 -10.5 tRNA dimethylallyltransferase compare
PFR28_04712 -2.4 -1.5 Dodecin compare
PFR28_03719 -2.4 -6.1 Poly(A) polymerase I compare
PFR28_05078 -2.3 -3.1 hypothetical protein compare
PFR28_00851 -2.3 -2.2 Flagellum site-determining protein YlxH compare
PFR28_05212 -2.2 -10.8 Sensor histidine kinase RcsC compare
PFR28_05134 -2.2 -3.3 hypothetical protein compare
PFR28_02838 -2.2 -8.6 Aromatic-amino-acid aminotransferase compare
PFR28_00913 -2.2 -5.0 Integration host factor subunit beta compare
PFR28_02449 -2.2 -8.5 putative branched-chain-amino-acid aminotransferase compare
PFR28_02846 -2.2 -6.9 Adaptive-response sensory-kinase SasA compare
PFR28_01265 -2.1 -6.6 (R)-benzylsuccinyl-CoA dehydrogenase compare
PFR28_01127 -2.1 -9.3 Soluble pyridine nucleotide transhydrogenase compare
PFR28_04491 -2.1 -2.8 putative acyl-CoA thioester hydrolase compare
PFR28_02127 -2.1 -2.4 hypothetical protein compare
PFR28_03748 -2.1 -6.1 Ribosomal large subunit pseudouridine synthase D compare
PFR28_00980 -2.0 -2.0 ATP-dependent RNA helicase DeaD compare
PFR28_00596 -1.9 -9.3 Glutamate-pyruvate aminotransferase AlaC compare
PFR28_01142 -1.8 -10.2 Transaldolase compare
PFR28_03844 -1.8 -5.2 Thiamine-phosphate synthase compare
PFR28_04830 -1.8 -9.0 Phosphoenolpyruvate-dependent phosphotransferase system compare
PFR28_00356 -1.7 -3.9 Protein-glutamate methylesterase/protein-glutamine glutaminase compare
PFR28_01113 -1.7 -3.3 DNA topoisomerase 1 compare
PFR28_03414 -1.7 -3.1 Crossover junction endodeoxyribonuclease RuvC compare
PFR28_02608 -1.7 -1.6 DNA translocase FtsK compare
PFR28_01876 -1.6 -1.4 hypothetical protein compare
PFR28_01372 -1.6 -2.4 Precorrin-4 C(11)-methyltransferase compare
PFR28_00941 -1.6 -1.3 Potassium-transporting ATPase KdpC subunit compare
PFR28_01060 -1.6 -4.8 HTH-type transcriptional repressor NanR compare
PFR28_02740 -1.4 -1.6 hypothetical protein compare
PFR28_00966 -1.4 -9.1 HTH-type transcriptional regulator CysB compare
PFR28_01376 -1.4 -1.9 hypothetical protein compare
PFR28_04585 -1.4 -5.0 Chromosome partitioning protein ParA compare
PFR28_01884 -1.4 -2.8 putative enoyl-CoA hydratase echA8 compare
PFR28_04262 -1.4 -4.8 Ribosomal RNA small subunit methyltransferase D compare
PFR28_00873 -1.4 -3.6 hypothetical protein compare
PFR28_00926 -1.3 -1.9 hypothetical protein compare
PFR28_03627 -1.3 -2.5 SOS response-associated protein YedK compare
PFR28_00730 -1.3 -2.7 5-oxoprolinase subunit C compare
PFR28_02613 -1.3 -6.9 ATP-dependent Clp protease ATP-binding subunit ClpA compare
PFR28_03412 -1.3 -3.0 Holliday junction ATP-dependent DNA helicase RuvB compare
PFR28_04903 -1.3 -5.1 hypothetical protein compare
PFR28_02727 -1.3 -2.2 Cold shock protein CapB compare
PFR28_04902 -1.3 -4.8 Inner membrane protein YgaZ compare
PFR28_02314 -1.3 -2.6 Fumarate and nitrate reduction regulatory protein compare
PFR28_01661 -1.3 -1.7 Delta(1)-pyrroline-2-carboxylate/Delta(1)- piperideine-2-carboxylate reductase compare
PFR28_05216 -1.2 -4.2 tRNA-dihydrouridine synthase B compare
PFR28_03854 -1.2 -3.9 hypothetical protein compare
PFR28_04418 -1.2 -2.0 Exodeoxyribonuclease compare
PFR28_04344 -1.2 -3.0 Exopolyphosphatase compare
PFR28_04396 -1.2 -4.6 HTH-type transcriptional regulator PuuR compare
PFR28_03086 -1.2 -6.7 Chaperone protein HtpG compare
PFR28_04030 -1.2 -7.8 hypothetical protein compare
PFR28_04607 -1.2 -1.3 Organic hydroperoxide resistance protein OhrB compare
PFR28_03413 -1.2 -2.7 Holliday junction ATP-dependent DNA helicase RuvA compare
PFR28_03657 -1.2 -4.0 Beta-barrel assembly-enhancing protease compare
PFR28_04297 -1.2 -5.9 Gamma-glutamylputrescine synthetase PuuA compare
PFR28_02704 -1.2 -0.9 hypothetical protein compare
PFR28_03816 -1.2 -6.6 Riboflavin transporter compare
PFR28_00839 -1.1 -3.7 hypothetical protein compare
PFR28_01927 -1.1 -3.8 Apulose-4-phosphate transketolase subunit A compare
PFR28_04369 -1.1 -1.4 hypothetical protein compare
PFR28_03279 -1.1 -5.5 N-succinylarginine dihydrolase compare
PFR28_03465 -1.1 -2.9 CS1 fimbrial subunit A compare
PFR28_02506 -1.1 -6.3 'Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase' transl_table=11 compare
PFR28_03530 -1.1 -0.9 hypothetical protein compare
PFR28_04252 -1.1 -4.3 Thiazole synthase compare
PFR28_03427 -1.1 -3.5 Sensor histidine kinase RcsC compare
PFR28_04103 -1.1 -5.0 Biotin synthase compare
PFR28_04485 -1.1 -2.0 Phosphate-specific transport system accessory protein PhoU compare
PFR28_03716 -1.1 -3.6 hypothetical protein compare
PFR28_01748 -1.1 -2.1 hypothetical protein compare
PFR28_02426 -1.1 -6.4 HTH-type transcriptional regulator MurR compare
PFR28_01644 -1.1 -1.5 hypothetical protein compare
PFR28_04963 -1.1 -4.2 HTH-type transcriptional repressor NagR compare
PFR28_00139 -1.1 -5.0 HTH-type transcriptional regulator LutR compare
PFR28_01081 -1.1 -2.6 hypothetical protein compare
PFR28_04473 -1.1 -1.5 DNA-binding protein HU-beta compare
PFR28_01375 -1.1 -1.7 hypothetical protein compare
PFR28_04568 -1.1 -3.5 Na(+)/H(+)-K(+) antiporter GerN compare
PFR28_00325 -1.0 -2.1 Inner membrane protein YpjD compare
PFR28_00787 -1.0 -2.4 hypothetical protein compare
PFR28_04236 -1.0 -3.3 Bifunctional protein PyrR compare
PFR28_00938 -1.0 -2.0 hypothetical protein compare
PFR28_04529 -1.0 -2.6 hypothetical protein compare
PFR28_02289 -1.0 -1.0 HTH-type transcriptional repressor NicS compare
PFR28_03843 -1.0 -3.9 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase compare
PFR28_05204 -1.0 -2.5 Sulfite reductase [ferredoxin] compare
PFR28_03018 -1.0 -5.7 Ribosomal large subunit pseudouridine synthase C compare
PFR28_03635 -1.0 -3.0 Malate:quinone oxidoreductase compare
PFR28_01435 -1.0 -1.8 Response regulator UvrY compare
PFR28_01600 -1.0 -1.0 HTH-type transcriptional regulator KdgR compare
PFR28_03272 -1.0 -1.2 Translational regulator CsrA2 compare
PFR28_00856 -1.0 -4.1 Protein-glutamate methylesterase/protein-glutamine glutaminase 1 compare
PFR28_03369 -1.0 -3.7 Glycerol-3-phosphate regulon repressor compare
PFR28_00064 -1.0 -5.7 Pyruvate dehydrogenase complex repressor compare
PFR28_00425 -1.0 -5.3 Protein-L-isoaspartate O-methyltransferase compare
PFR28_01230 -0.9 -3.2 Lon protease compare
PFR28_00860 -0.9 -3.9 hypothetical protein compare
PFR28_04681 -0.9 -1.8 hypothetical protein compare
PFR28_01378 -0.9 -2.3 Magnesium-chelatase 38 kDa subunit compare
PFR28_05091 -0.9 -7.2 Phosphomethylpyrimidine synthase compare
PFR28_00728 -0.9 -4.6 5-oxoprolinase subunit A 3 compare
PFR28_02592 -0.9 -3.0 Peroxyureidoacrylate/ureidoacrylate amidohydrolase RutB compare
PFR28_03883 -0.9 -4.1 UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl- meso-2,6-diaminoheptandioate ligase compare
PFR28_01263 -0.9 -2.7 HTH-type transcriptional regulator CueR compare
PFR28_02100 -0.9 -0.8 hypothetical protein compare
PFR28_03552 -0.9 -5.2 hypothetical protein compare
PFR28_02719 -0.9 -3.2 Integration host factor subunit alpha compare
PFR28_04461 -0.9 -1.1 hypothetical protein compare
PFR28_04377 -0.9 -2.3 hypothetical protein compare
PFR28_03596 -0.9 -1.1 Transcriptional regulator MraZ compare
PFR28_01774 -0.9 -2.4 hypothetical protein compare
PFR28_04586 -0.9 -3.8 Ribosomal RNA small subunit methyltransferase G compare
PFR28_04345 -0.9 -6.2 Polyphosphate kinase compare
PFR28_04865 -0.9 -4.2 Glutamate--cysteine ligase compare
PFR28_03310 -0.9 -2.2 Peptidyl-tRNA hydrolase ArfB compare
PFR28_04222 -0.9 -1.9 '2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase' transl_table=11 compare
PFR28_04633 -0.9 -1.7 Alginate biosynthesis sensor protein KinB compare
PFR28_01003 -0.9 -3.2 hypothetical protein compare
PFR28_01881 -0.9 -1.5 putative oxidoreductase compare
PFR28_03615 -0.9 -3.8 hypothetical protein compare


Specific Phenotypes

For 13 genes in this experiment

For carbon source Hydroxy-L-Proline in Pseudomonas sp. RS175

For carbon source Hydroxy-L-Proline across organisms