Experiment set19IT084 for Escherichia coli BW25113

Compare to:

P2 dilution 10-3 cacl2

200 most important genes:

  gene name fitness t score description  
b0888 trxB -4.3 -5.1 thioredoxin reductase, FAD/NAD(P)-binding (NCBI) compare
b0439 lon -3.6 -5.5 DNA-binding ATP-dependent protease La (NCBI) compare
b2819 recD -3.5 -10.8 exonuclease V (RecBCD complex), alpha chain (NCBI) compare
b3839 tatC -3.4 -8.9 TatABCE protein translocation system subunit (NCBI) compare
b2830 nudH -3.1 -2.1 dinucleoside polyphosphate hydrolase (NCBI) compare
b0053 surA -3.0 -7.1 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b2620 smpB -3.0 -2.7 SsrA-binding protein (NCBI) compare
b1860 ruvB -2.7 -1.8 Holliday junction DNA helicase B (NCBI) compare
b0912 ihfB -2.6 -6.2 integration host factor subunit beta (NCBI) compare
b4603 rseX -2.6 -1.2 sRNA regulating ompA and ompC translation, with Hfq (RefSeq) compare
b1293 sapB -2.5 -2.9 predicted antimicrobial peptide transporter subunit (NCBI) compare
b4171 miaA -2.4 -4.3 tRNA delta(2)-isopentenylpyrophosphate transferase (NCBI) compare
b3816 corA -2.4 -11.1 magnesium/nickel/cobalt transporter (NCBI) compare
b0683 fur -2.3 -2.9 ferric uptake regulator (NCBI) compare
b3390 aroK -2.2 -3.0 shikimate kinase I (NCBI) compare
b2501 ppk -2.2 -11.2 polyphosphate kinase (NCBI) compare
b1493 gadB -2.1 -1.7 glutamate decarboxylase B, PLP-dependent (NCBI) compare
b3613 yibP -2.1 -4.2 putative membrane protein (VIMSS) compare
b1361 ydaW -2.1 -0.9 orf, hypothetical protein (VIMSS) compare
b0890 ftsK -2.0 -4.6 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b3706 trmE -2.0 -4.9 tRNA modification GTPase (NCBI) compare
b3741 gidA -1.9 -3.5 glucose-inhibited division protein A (NCBI) compare
b3781 trxA -1.9 -3.8 thioredoxin 1 (VIMSS) compare
b3628 rfaB -1.9 -10.6 UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase (RefSeq) compare
b3977 tyrU -1.9 -1.5 tRNA-Tyr (NCBI) compare
b3630 rfaP -1.9 -10.4 kinase that phosphorylates core heptose of lipopolysaccharide (NCBI) compare
b0730 mngR -1.8 -2.1 DNA-binding transcriptional dual regulator, fatty-acyl-binding (NCBI) compare
b2912 ygfA -1.8 -4.5 putative ligase (VIMSS) compare
b4402 yjjY -1.8 -1.4 hypothetical protein (NCBI) compare
b3916 pfkA -1.8 -2.6 6-phosphofructokinase (NCBI) compare
b2935 tktA -1.8 -2.0 transketolase 1, thiamin-binding (NCBI) compare
b1290 sapF -1.7 -2.7 predicted antimicrobial peptide transporter subunit (NCBI) compare
b2814 metZ -1.7 -2.4 tRNA-Met (NCBI) compare
b2846 yqeH -1.6 -1.1 orf, hypothetical protein (VIMSS) compare
b2569 lepA -1.6 -5.0 GTP-binding protein LepA (NCBI) compare
b4146 yjeK -1.6 -1.5 predicted lysine aminomutase (NCBI) compare
b4527 b1354 -1.5 -5.2 orf, hypothetical protein (VIMSS) compare
b4593 ymgI -1.5 -0.9 hypothetical protein (RefSeq) compare
b3863 polA -1.5 -1.9 DNA polymerase I (NCBI) compare
b0688 pgm -1.5 -4.4 phosphoglucomutase (NCBI) compare
b4201 priB -1.4 -3.4 primosomal replication protein N (NCBI) compare
b3652 recG -1.4 -8.8 ATP-dependent DNA helicase (NCBI) compare
b0767 ybhE -1.4 -3.7 6-phosphogluconolactonase (NCBI) compare
b2822 recC -1.4 -3.6 exonuclease V (RecBCD complex), gamma chain (NCBI) compare
b1827 kdgR -1.4 -4.0 predicted DNA-binding transcriptional regulator (NCBI) compare
b0167 glnD -1.4 -4.7 PII uridylyl-transferase (NCBI) compare
b4535 yniD -1.4 -1.5 predicted protein (RefSeq) compare
b0630 lipB -1.4 -1.9 protein of lipoate biosynthesis (VIMSS) compare
b1286 rnb -1.4 -2.2 exoribonuclease II (NCBI) compare
b0142 folK -1.4 -0.9 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase (NCBI) compare
b3979 thrT -1.3 -0.6 tRNA-Thr (NCBI) compare
b1291 sapD -1.3 -1.8 predicted antimicrobial peptide transporter subunit (NCBI) compare
b4025 pgi -1.3 -7.7 glucose-6-phosphate isomerase (NCBI) compare
b1355 b1355 -1.3 -2.5 orf, hypothetical protein (VIMSS) compare
b4179 vacB -1.3 -6.0 putative enzyme (VIMSS) compare
b3183 obgE -1.2 -1.7 GTPase involved in cell partioning and DNA repair (NCBI) compare
b3405 ompR -1.2 -4.4 osmolarity response regulator (NCBI) compare
b2699 recA -1.2 -1.1 recombinase A (NCBI) compare
b2318 truA -1.2 -3.4 tRNA pseudouridine synthase A (NCBI) compare
b0739 tolA -1.2 -3.2 cell envelope integrity inner membrane protein TolA (NCBI) compare
b1187 fadR -1.2 -6.2 fatty acid metabolism regulator (NCBI) compare
b1712 ihfA -1.2 -1.1 integration host factor subunit alpha (NCBI) compare
b3811 xerC -1.2 -1.9 site-specific tyrosine recombinase XerC (NCBI) compare
b1863 ruvC -1.2 -1.9 Holliday junction resolvase (NCBI) compare
b1292 sapC -1.2 -2.3 predicted antimicrobial peptide transporter subunit (NCBI) compare
b0738 tolR -1.1 -2.4 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b3290 trkA -1.1 -1.7 potassium transporter peripheral membrane component (NCBI) compare
b2518 ndk -1.1 -2.8 nucleoside diphosphate kinase (NCBI) compare
b0114 aceE -1.1 -0.8 pyruvate dehydrogenase subunit E1 (NCBI) compare
b4239 treC -1.1 -1.7 trehalose-6-P hydrolase (NCBI) compare
b4520 ymgF -1.1 -2.0 hypothetical protein (NCBI) compare
b4701 sokX -1.1 -1.2 sok-related sRNA, function unknown (RefSeq) compare
b2431 b2431 -1.1 -6.2 orf, hypothetical protein (VIMSS) compare
b1109 ndh -1.1 -4.0 respiratory NADH dehydrogenase 2/cupric reductase (NCBI) compare
b3787 rffD -1.1 -7.5 UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase (NCBI) compare
b1130 phoP -1.1 -1.3 DNA-binding response regulator in two-component regulatory system with PhoQ (NCBI) compare
b2895 fldB -1.1 -3.6 flavodoxin 2 (NCBI) compare
b0605 ahpC -1.1 -3.3 alkyl hydroperoxide reductase, C22 subunit (NCBI) compare
b4522 yciX_1 -1.1 -2.9 hypothetical protein (NCBI) compare
b3844 fre -1.0 -5.5 NAD(P)H-flavin reductase (NCBI) compare
b1105 ycfM -1.0 -4.2 predicted outer membrane lipoprotein (NCBI) compare
b3790 rffC -1.0 -5.0 TDP-fucosamine acetyltransferase (RefSeq) compare
b3778 rep -1.0 -6.0 DNA helicase and single-stranded DNA-dependent ATPase (NCBI) compare
b3838 tatB -1.0 -3.5 sec-independent translocase (NCBI) compare
b3725 pstB -1.0 -0.7 phosphate transporter subunit (NCBI) compare
b3842 rfaH -1.0 -4.7 transcriptional activator RfaH (NCBI) compare
b4006 purH -1.0 -7.3 bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (NCBI) compare
b3794 rffM -1.0 -5.1 putative UDP-N-acetyl-D-mannosaminuronic acid transferase (NCBI) compare
b1861 ruvA -1.0 -1.2 Holliday junction DNA helicase motor protein (NCBI) compare
b1907 tyrP -0.9 -4.4 tyrosine transporter (NCBI) compare
b3204 ptsN -0.9 -3.9 sugar-specific enzyme IIA component of PTS (NCBI) compare
b3238 yhcN -0.9 -2.0 orf, hypothetical protein (VIMSS) compare
b1269 rluB -0.9 -2.4 23S rRNA pseudouridylate synthase (NCBI) compare
b2531 iscR -0.9 -1.4 DNA-binding transcriptional repressor (NCBI) compare
b1984 asnW -0.9 -1.2 tRNA-Asn (NCBI) compare
b4552 yrhC -0.9 -0.9 no description compare
b0406 tgt -0.9 -4.2 queuine tRNA-ribosyltransferase (NCBI) compare
b3389 aroB -0.9 -6.1 3-dehydroquinate synthase (NCBI) compare
b2528 iscA -0.9 -1.4 iron-sulfur cluster assembly protein (NCBI) compare
b4613 dinQ -0.9 -1.9 Damage inducible, function unknown (RefSeq) compare
b1175 minD -0.9 -4.1 membrane ATPase of the MinC-MinD-MinE system (NCBI) compare
b0741 pal -0.9 -2.9 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b3169 nusA -0.9 -2.7 transcription elongation factor NusA (NCBI) compare
b1804 rnd -0.9 -3.7 ribonuclease D (NCBI) compare
b3281 aroE -0.9 -6.9 dehydroshikimate reductase, NAD(P)-binding (NCBI) compare
b2498 upp -0.9 -2.3 uracil phosphoribosyltransferase (VIMSS) compare
b3163 nlpI -0.9 -3.0 hypothetical protein (NCBI) compare
b0726 sucA -0.9 -2.3 alpha-ketoglutarate decarboxylase (NCBI) compare
b3017 sufI -0.9 -6.0 repressor protein for FtsI (NCBI) compare
b3465 yhhF -0.9 -4.3 predicted methyltransferase (NCBI) compare
b1739 osmE -0.9 -1.5 DNA-binding transcriptional activator (NCBI) compare
b2892 recJ -0.8 -6.0 ssDNA exonuclease, 5' --> 3'-specific (NCBI) compare
b1593 b1593 -0.8 -2.2 orf, hypothetical protein (VIMSS) compare
b4172 hfq -0.8 -0.5 RNA-binding protein Hfq (NCBI) compare
b2393 nupC -0.8 -3.9 nucleoside (except guanosine) transporter (NCBI) compare
b3205 yhbJ -0.8 -3.0 hypothetical protein (NCBI) compare
b1353 sieB -0.8 -3.4 phage superinfection exclusion protein (VIMSS) compare
b4202 rpsR -0.8 -1.2 30S ribosomal protein S18 (NCBI) compare
b4481 rffT -0.8 -4.2 4-alpha-L-fucosyltransferase (NCBI) compare
b3868 glnG -0.8 -3.4 fused DNA-binding response regulator in two-component regulatory system with GlnL: response regulator/sigma54 interaction protein (NCBI) compare
b3210 arcB -0.8 -4.6 hybrid sensory histidine kinase in two-component regulatory system with ArcA (NCBI) compare
b1025 ycdT -0.7 -1.1 predicted diguanylate cyclase (NCBI) compare
b0251 yafY -0.7 -2.7 CP4-6 prophage; predicted DNA-binding transcriptional regulator (RefSeq) compare
b0149 mrcB -0.7 -5.9 penicillin-binding protein 1b (NCBI) compare
b1183 umuD -0.7 -2.0 DNA polymerase V, subunit D (NCBI) compare
b0429 cyoD -0.7 -3.4 cytochrome o ubiquinol oxidase subunit IV (NCBI) compare
b3484 yhhI -0.7 -2.1 predicted transposase (NCBI) compare
b3728 pstS -0.7 -2.2 phosphate transporter subunit (NCBI) compare
b1573 ydfC -0.7 -1.1 Qin prophage; predicted protein (RefSeq) compare
b3198 kdsC -0.7 -1.7 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (NCBI) compare
b3237 argR -0.7 -2.4 arginine repressor (NCBI) compare
b2906 visC -0.7 -4.1 hypothetical protein (NCBI) compare
b0740 tolB -0.7 -2.8 translocation protein TolB precursor (NCBI) compare
b3933 ftsN -0.7 -4.6 essential cell division protein (NCBI) compare
b0143 pcnB -0.7 -2.9 poly(A) polymerase I (VIMSS) compare
b1651 gloA -0.7 -2.6 glyoxalase I, Ni-dependent (NCBI) compare
b3426 glpD -0.7 -2.2 sn-glycerol-3-phosphate dehydrogenase, aerobic, FAD/NAD(P)-binding (NCBI) compare
b1613 manA -0.7 -1.4 mannose-6-phosphate isomerase (VIMSS) compare
b2038 rfbC -0.7 -3.8 dTDP-4-deoxyrhamnose-3,5-epimerase (NCBI) compare
b2820 recB -0.7 -0.5 exonuclease V (RecBCD complex), beta subunit (NCBI) compare
b2156 lysP -0.7 -4.9 lysine transporter (NCBI) compare
b4592 yccB -0.7 -1.2 hypothetical protein (RefSeq) compare
b3786 rffE -0.7 -5.0 UDP-N-acetyl glucosamine-2-epimerase (NCBI) compare
b3791 rffA -0.7 -4.1 TDP-4-oxo-6-deoxy-D-glucose transaminase (NCBI) compare
b0082 mraW -0.7 -2.4 S-adenosyl-methyltransferase (NCBI) compare
b3813 uvrD -0.7 -5.2 DNA-dependent ATPase I and helicase II (NCBI) compare
b2282 nuoH -0.7 -1.8 NADH dehydrogenase subunit H (NCBI) compare
b2114 metG -0.7 -1.7 methionyl-tRNA synthetase (NCBI) compare
b0990 cspG -0.7 -0.6 DNA-binding transcriptional regulator (NCBI) compare
b0989 cspH -0.7 -1.7 stress protein, member of the CspA-family (NCBI) compare
b3289 rsmB -0.7 -4.7 16S rRNA m5C967 methyltransferase, S-adenosyl-L-methionine-dependent (NCBI) compare
b1161 ycgX -0.7 -0.7 hypothetical protein (NCBI) compare
b1129 phoQ -0.7 -0.8 sensory histidine kinase in two-compoent regulatory system with PhoP (NCBI) compare
b3414 gntY -0.7 -3.5 predicted gluconate transport associated protein (NCBI) compare
b2937 speB -0.6 -3.4 agmatinase (NCBI) compare
b1693 aroD -0.6 -2.9 3-dehydroquinate dehydratase (NCBI) compare
b1865 nudB -0.6 -1.0 dATP pyrophosphohydrolase (NCBI) compare
b3026 qseC -0.6 -2.5 sensory histidine kinase in two-component regulatory system with QseB (NCBI) compare
b4494 arpB -0.6 -1.2 no description compare
b0469 apt -0.6 -3.5 adenine phosphoribosyltransferase (NCBI) compare
b4504 ykfH -0.6 -2.7 hypothetical protein (NCBI) compare
b4383 deoB -0.6 -4.4 phosphopentomutase (NCBI) compare
b0564 appY -0.6 -0.9 DLP12 prophage; DNA-binding transcriptional activator (NCBI) compare
b4585 sroB -0.6 -0.9 Novel sRNA, function unknown (RefSeq) compare
b1676 pykF -0.6 -1.9 pyruvate kinase (NCBI) compare
b4042 dgkA -0.6 -1.2 diacylglycerol kinase (NCBI) compare
b3387 dam -0.6 -4.8 DNA adenine methylase (NCBI) compare
b3803 hemX -0.6 -4.0 predicted uroporphyrinogen III methylase (NCBI) compare
b3146 yraL -0.6 -3.8 predicted methyltransferase (NCBI) compare
b1176 minC -0.6 -2.0 septum formation inhibitor (NCBI) compare
b2900 yqfB -0.6 -2.7 hypothetical protein (NCBI) compare
b1551 b1551 -0.6 -0.3 orf, hypothetical protein (VIMSS) compare
b0161 degP -0.6 -3.1 serine endoprotease (protease Do), membrane-associated (NCBI) compare
b3181 greA -0.6 -2.6 transcription elongation factor: cleaves 3' nucleotide of paused mRNA (VIMSS) compare
b1671 ydhX -0.6 -1.4 predicted 4Fe-4S ferridoxin-type protein (RefSeq) compare
b0535 fimZ -0.6 -1.9 predicted DNA-binding transcriptional regulator (NCBI) compare
b1506 yneL -0.6 -0.9 predicted transcriptional regulator (NCBI) compare
b4413 sokC -0.6 -1.2 regulatory antisense RNA (NCBI) compare
b0976 hyaE -0.6 -2.0 protein involved in processing of HyaA and HyaB proteins (NCBI) compare
b2319 usg -0.6 -2.2 hypothetical protein (NCBI) compare
b2058 wcaB -0.6 -0.8 predicted acyl transferase (NCBI) compare
b2954 yggV -0.6 -2.5 putative deoxyribonucleotide triphosphate pyrophosphatase (NCBI) compare
b1103 ycfF -0.6 -0.9 orf, hypothetical protein (VIMSS) compare
b4384 deoD -0.6 -3.9 purine nucleoside phosphorylase (NCBI) compare
b2143 cdd -0.6 -2.6 cytidine deaminase (NCBI) compare
b1862 yebB -0.5 -1.7 orf, hypothetical protein (VIMSS) compare
b0407 yajC -0.5 -1.3 preprotein translocase subunit YajC (NCBI) compare
b1754 b1754 -0.5 -1.7 orf, hypothetical protein (VIMSS) compare
b2512 yfgL -0.5 -2.7 protein assembly complex, lipoprotein component (NCBI) compare
b2934 cmtB -0.5 -0.5 predicted mannitol-specific enzyme IIA component of PTS (NCBI) compare
b2435 amiA -0.5 -3.0 N-acetylmuramoyl-l-alanine amidase I (NCBI) compare
b0522 purK -0.5 -3.5 phosphoribosylaminoimidazole carboxylase (NCBI) compare
b3443 yrhA -0.5 -0.5 orf, hypothetical protein (VIMSS) compare
b0841 ybjG -0.5 -2.8 undecaprenyl pyrophosphate phosphatase (NCBI) compare
b2236 yfaE -0.5 -2.0 predicted 2Fe-2S cluster-containing protein (NCBI) compare
b3858 yihD -0.5 -1.5 hypothetical protein (NCBI) compare
b3870 glnA -0.5 -1.8 glutamine synthetase (NCBI) compare
b1346 ydaQ -0.5 -0.6 orf, hypothetical protein (VIMSS) compare
b3650 spoT -0.5 -2.5 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (NCBI) compare
b0737 tolQ -0.5 -1.3 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare


Specific Phenotypes

For 4 genes in this experiment

For phage P2_phage in Escherichia coli BW25113

For phage P2_phage across organisms