Experiment set19IT072 for Escherichia coli BW25113

Compare to:

No phage control ML9a

200 most important genes:

  gene name fitness t score description  
b3183 obgE -3.1 -2.1 GTPase involved in cell partioning and DNA repair (NCBI) compare
b0142 folK -2.9 -1.4 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase (NCBI) compare
b3839 tatC -2.8 -10.9 TatABCE protein translocation system subunit (NCBI) compare
b3816 corA -2.7 -11.6 magnesium/nickel/cobalt transporter (NCBI) compare
b4535 yniD -2.7 -2.5 predicted protein (RefSeq) compare
b0053 surA -2.3 -6.5 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b1860 ruvB -2.3 -1.5 Holliday junction DNA helicase B (NCBI) compare
b0439 lon -2.2 -6.6 DNA-binding ATP-dependent protease La (NCBI) compare
b3979 thrT -2.0 -1.0 tRNA-Thr (NCBI) compare
b3341 rpsG -1.9 -1.6 30S ribosomal protein S7 (NCBI) compare
b0630 lipB -1.8 -1.2 protein of lipoate biosynthesis (VIMSS) compare
b1865 nudB -1.7 -2.1 dATP pyrophosphohydrolase (NCBI) compare
b1291 sapD -1.7 -2.7 predicted antimicrobial peptide transporter subunit (NCBI) compare
b4177 purA -1.7 -1.2 adenylosuccinate synthetase (NCBI) compare
b2281 nuoI -1.6 -3.7 NADH dehydrogenase subunit I (NCBI) compare
b4042 dgkA -1.6 -2.1 diacylglycerol kinase (NCBI) compare
b2894 xerD -1.6 -1.4 site-specific tyrosine recombinase XerD (NCBI) compare
b3500 gor -1.5 -1.8 glutathione reductase (NCBI) compare
b2318 truA -1.5 -3.1 tRNA pseudouridine synthase A (NCBI) compare
b2287 nuoB -1.5 -3.6 NADH dehydrogenase subunit B (NCBI) compare
b2699 recA -1.5 -1.0 recombinase A (NCBI) compare
b2935 tktA -1.5 -1.4 transketolase 1, thiamin-binding (NCBI) compare
b2830 nudH -1.4 -1.6 dinucleoside polyphosphate hydrolase (NCBI) compare
b2276 nuoN -1.4 -6.0 NADH:ubiquinone oxidoreductase, membrane subunit N (RefSeq) compare
b3778 rep -1.4 -7.6 DNA helicase and single-stranded DNA-dependent ATPase (NCBI) compare
b1730 ydjO -1.4 -1.2 predicted protein (RefSeq) compare
b0890 ftsK -1.4 -4.0 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b1160 elbA -1.3 -0.9 hypothetical protein (NCBI) compare
b0740 tolB -1.3 -4.0 translocation protein TolB precursor (NCBI) compare
b3619 rfaD -1.3 -3.7 ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) compare
b2284 nuoF -1.3 -4.4 NADH:ubiquinone oxidoreductase, chain F (NCBI) compare
b3761 trpT -1.3 -2.3 tRNA-Trp (NCBI) compare
b3164 pnp -1.2 -2.9 polynucleotide phosphorylase/polyadenylase (RefSeq) compare
b2280 nuoJ -1.2 -3.7 NADH dehydrogenase subunit J (NCBI) compare
b2277 nuoM -1.2 -5.3 NADH dehydrogenase subunit M (NCBI) compare
b1161 ycgX -1.2 -1.1 hypothetical protein (NCBI) compare
b2431 b2431 -1.2 -6.7 orf, hypothetical protein (VIMSS) compare
b3844 fre -1.2 -5.0 NAD(P)H-flavin reductase (NCBI) compare
b2822 recC -1.2 -4.4 exonuclease V (RecBCD complex), gamma chain (NCBI) compare
b2620 smpB -1.1 -1.1 SsrA-binding protein (NCBI) compare
b2168 fruK -1.1 -1.5 1-phosphofructokinase (NCBI) compare
b0049 apaH -1.1 -3.1 diadenosinetetraphosphatase (NCBI) compare
b3741 gidA -1.1 -3.7 glucose-inhibited division protein A (NCBI) compare
b0737 tolQ -1.1 -2.4 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b2531 iscR -1.1 -1.9 DNA-binding transcriptional repressor (NCBI) compare
b4593 ymgI -1.1 -1.2 hypothetical protein (RefSeq) compare
b2278 nuoL -1.1 -6.9 NADH dehydrogenase subunit L (NCBI) compare
b1292 sapC -1.1 -2.1 predicted antimicrobial peptide transporter subunit (NCBI) compare
b0627 tatE -1.1 -2.0 twin arginine translocase protein E (NCBI) compare
b2906 visC -1.1 -5.6 hypothetical protein (NCBI) compare
b2820 recB -1.1 -1.2 exonuclease V (RecBCD complex), beta subunit (NCBI) compare
b3706 trmE -1.0 -3.3 tRNA modification GTPase (NCBI) compare
b1332 ynaJ -1.0 -1.1 predicted inner membrane protein (NCBI) compare
b2285 nuoE -1.0 -2.2 NADH dehydrogenase subunit E (NCBI) compare
b3162 deaD -1.0 -4.2 inducible ATP-independent RNA helicase (VIMSS) compare
b1290 sapF -1.0 -1.5 predicted antimicrobial peptide transporter subunit (NCBI) compare
b3052 rfaE -1.0 -4.1 fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) compare
b2286 nuoC -1.0 -3.9 NADH:ubiquinone oxidoreductase, chain C,D (RefSeq) compare
b2288 nuoA -1.0 -2.3 NADH dehydrogenase I chain A (VIMSS) compare
b0200 gmhB -1.0 -1.5 hypothetical protein (NCBI) compare
b2282 nuoH -1.0 -2.9 NADH dehydrogenase subunit H (NCBI) compare
b4239 treC -1.0 -1.6 trehalose-6-P hydrolase (NCBI) compare
b2518 ndk -1.0 -2.5 nucleoside diphosphate kinase (NCBI) compare
b2258 b2258 -1.0 -1.3 putative transport/receptor protein (VIMSS) compare
b1286 rnb -1.0 -1.9 exoribonuclease II (NCBI) compare
b2567 rnc -0.9 -0.9 ribonuclease III (NCBI) compare
b1129 phoQ -0.9 -0.6 sensory histidine kinase in two-compoent regulatory system with PhoP (NCBI) compare
b1257 yciE -0.9 -0.5 hypothetical protein (NCBI) compare
b1548 nohA -0.9 -1.6 Qin prophage; predicted packaging protein (RefSeq) compare
b1351 racC -0.9 -0.6 Rac prophage; predicted protein (NCBI) compare
b1164 ycgZ -0.9 -1.2 hypothetical protein (NCBI) compare
b1628 rsxB -0.9 -2.8 electron transport complex protein RnfB (NCBI) compare
b0721 sdhC -0.9 -3.3 succinate dehydrogenase cytochrome b556 large membrane subunit (NCBI) compare
b1347 ydaC -0.9 -0.5 Rac prophage; predicted protein (NCBI) compare
b0051 ksgA -0.9 -3.4 dimethyladenosine transferase (NCBI) compare
b1762 b1762 -0.9 -1.8 orf, hypothetical protein (VIMSS) compare
b4655 ythA -0.8 -1.1 expressed protein (RefSeq) compare
b1176 minC -0.8 -2.4 septum formation inhibitor (NCBI) compare
b1556 b1556 -0.8 -2.1 orf, hypothetical protein (VIMSS) compare
b4410 ecnA -0.8 -1.4 entericidin A membrane lipoprotein, antidote entericidin B (NCBI) compare
b1183 umuD -0.8 -1.3 DNA polymerase V, subunit D (NCBI) compare
b0688 pgm -0.8 -3.0 phosphoglucomutase (NCBI) compare
b3237 argR -0.8 -3.5 arginine repressor (NCBI) compare
b3977 tyrU -0.8 -0.9 tRNA-Tyr (NCBI) compare
b0738 tolR -0.8 -2.1 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b2947 gshB -0.8 -3.2 glutathione synthetase (NCBI) compare
b3620 rfaF -0.8 -3.5 ADP-heptose:LPS heptosyltransferase II (NCBI) compare
b4179 vacB -0.8 -3.9 putative enzyme (VIMSS) compare
b2912 ygfA -0.8 -2.4 putative ligase (VIMSS) compare
b1505 ydeT -0.8 -0.8 hypothetical protein (RefSeq) compare
b3026 qseC -0.8 -2.8 sensory histidine kinase in two-component regulatory system with QseB (NCBI) compare
b1951 rcsA -0.8 -1.1 DNA-binding transcriptional activator, co-regulator with RcsB (NCBI) compare
b2688 gshA -0.8 -3.7 glutamate--cysteine ligase (NCBI) compare
b1409 ynbB -0.8 -0.5 predicted CDP-diglyceride synthase (NCBI) compare
b4435 isrC -0.8 -1.3 unknown RNA (NCBI) compare
b2283 nuoG -0.8 -4.3 NADH:ubiquinone oxidoreductase, chain G (RefSeq) compare
b0782 moaB -0.8 -1.8 molybdopterin biosynthesis protein B (NCBI) compare
b1558 cspF -0.8 -1.7 Qin prophage; cold shock protein (NCBI) compare
b0500 ybbD -0.8 -0.5 hypothetical protein (RefSeq) compare
b1758 b1758 -0.8 -1.1 putative cytochrome oxidase (VIMSS) compare
b1679 sufE -0.7 -1.7 cysteine desufuration protein SufE (NCBI) compare
b0430 cyoC -0.7 -2.2 cytochrome o ubiquinol oxidase subunit III (NCBI) compare
b2576 srmB -0.7 -2.2 ATP-dependent RNA helicase (NCBI) compare
b2895 fldB -0.7 -2.0 flavodoxin 2 (NCBI) compare
b0088 murD -0.7 -1.3 UDP-N-acetylmuramoyl-L-alanyl-D-glutamatesynthetase (NCBI) compare
b1293 sapB -0.7 -0.8 predicted antimicrobial peptide transporter subunit (NCBI) compare
b4595 yciY -0.7 -1.9 hypothetical protein (RefSeq) compare
b3075 ebgR -0.7 -3.4 DNA-binding transcriptional repressor (NCBI) compare
b0730 mngR -0.7 -1.1 DNA-binding transcriptional dual regulator, fatty-acyl-binding (NCBI) compare
b3390 aroK -0.7 -1.2 shikimate kinase I (NCBI) compare
b3623 rfaK -0.7 -1.5 lipopolysaccharide core biosynthesis (NCBI) compare
b0222 lpcA -0.7 -2.0 phosphoheptose isomerase (NCBI) compare
b2569 lepA -0.7 -2.8 GTP-binding protein LepA (NCBI) compare
b1258 yciF -0.7 -0.7 hypothetical protein (NCBI) compare
b3811 xerC -0.7 -0.9 site-specific tyrosine recombinase XerC (NCBI) compare
b4431 rprA -0.7 -1.5 Positive regulatory sRNA for RpoS translation; non-essential gene (RefSeq) compare
b2325 yfcL -0.7 -2.3 hypothetical protein (NCBI) compare
b1575 dicB -0.7 -1.2 Qin prophage; cell division inhibition protein (NCBI) compare
b3613 yibP -0.7 -2.1 putative membrane protein (VIMSS) compare
b0080 fruR -0.7 -3.6 DNA-binding transcriptional dual regulator (NCBI) compare
b1863 ruvC -0.7 -1.3 Holliday junction resolvase (NCBI) compare
b1363 trkG -0.7 -0.5 Rac prophage; potassium transporter subunit (NCBI) compare
b2279 nuoK -0.7 -1.1 NADH dehydrogenase subunit K (NCBI) compare
b1497 b1497 -0.7 -0.3 putative enzyme (VIMSS) compare
b1499 ydeO -0.7 -0.3 predicted DNA-binding transcriptional acfivator (NCBI) compare
b1109 ndh -0.7 -2.6 respiratory NADH dehydrogenase 2/cupric reductase (NCBI) compare
b1545 pinQ -0.7 -0.2 Qin prophage; predicted site-specific recombinase (NCBI) compare
b1551 b1551 -0.6 -0.3 orf, hypothetical protein (VIMSS) compare
b3405 ompR -0.6 -2.7 osmolarity response regulator (NCBI) compare
b1576 ydfD -0.6 -0.3 Qin prophage; predicted protein (NCBI) compare
b4411 ecnB -0.6 -2.1 entericidin B membrane lipoprotein (NCBI) compare
b1185 dsbB -0.6 -1.5 reoxidizes DsbA protein following formation of disulfide bond in P-ring of flagella. (VIMSS) compare
b4509 ylcG -0.6 -2.0 DLP12 prophage; predicted protein (NCBI) compare
b1192 ldcA -0.6 -2.4 L,D-carboxypeptidase A (NCBI) compare
b1182 hlyE -0.6 -0.4 hemolysin E (VIMSS) compare
b0178 hlpA -0.6 -2.2 periplasmic chaperone (NCBI) compare
b1438 ydcQ -0.6 -2.5 predicted DNA-binding transcriptional regulator (RefSeq) compare
b1850 eda -0.6 -1.5 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (NCBI) compare
b3916 pfkA -0.6 -1.6 6-phosphofructokinase (NCBI) compare
b4202 rpsR -0.6 -0.9 30S ribosomal protein S18 (NCBI) compare
b1165 ymgA -0.6 -0.4 hypothetical protein (NCBI) compare
b4181 yjfI -0.6 -1.9 hypothetical protein (NCBI) compare
b1493 gadB -0.6 -0.7 glutamate decarboxylase B, PLP-dependent (NCBI) compare
b1691 ydiN -0.6 -2.0 predicted transporter (RefSeq) compare
b0585 fes -0.6 -2.9 enterobactin/ferric enterobactin esterase (NCBI) compare
b1600 mdtJ -0.6 -1.1 multidrug efflux system transporter (NCBI) compare
b4594 ymgJ -0.6 -1.6 hypothetical protein (RefSeq) compare
b0726 sucA -0.6 -2.2 alpha-ketoglutarate decarboxylase (NCBI) compare
b1503 ydeR -0.6 -1.9 predicted fimbrial-like adhesin protein (NCBI) compare
b4178 yjeB -0.6 -2.2 predicted DNA-binding transcriptional regulator (NCBI) compare
b0724 sdhB -0.6 -3.5 succinate dehydrogenase, FeS subunit (NCBI) compare
b3636 rpmG -0.6 -1.4 50S ribosomal protein L33 (NCBI) compare
b1273 yciN -0.6 -1.2 hypothetical protein (NCBI) compare
b3290 trkA -0.6 -1.1 potassium transporter peripheral membrane component (NCBI) compare
b4494 arpB -0.6 -1.2 no description compare
b3742 mioC -0.6 -1.9 flavodoxin (NCBI) compare
b0143 pcnB -0.6 -2.8 poly(A) polymerase I (VIMSS) compare
b3443 yrhA -0.6 -0.9 orf, hypothetical protein (VIMSS) compare
b2330 yfcB -0.6 -0.9 putative adenine-specific methylase (VIMSS) compare
b2376 ypdI -0.6 -1.7 predicted lipoprotein involved in colanic acid biosynthesis (NCBI) compare
b2501 ppk -0.6 -3.8 polyphosphate kinase (NCBI) compare
b0741 pal -0.6 -1.9 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b3863 polA -0.6 -0.7 DNA polymerase I (NCBI) compare
b0866 ybjQ -0.6 -0.9 hypothetical protein (NCBI) compare
b0303 ykgI -0.6 -0.4 orf, hypothetical protein (VIMSS) compare
b0438 clpX -0.6 -3.2 ATP-dependent protease ATP-binding subunit (NCBI) compare
b1175 minD -0.6 -2.3 membrane ATPase of the MinC-MinD-MinE system (NCBI) compare
b2897 ygfY -0.6 -2.0 hypothetical protein (NCBI) compare
b1785 yeaI -0.6 -1.5 predicted diguanylate cyclase (NCBI) compare
b1739 osmE -0.6 -1.6 DNA-binding transcriptional activator (NCBI) compare
b4642 yoeD -0.6 -2.0 no description compare
b1690 ydiM -0.6 -1.4 predicted transporter (NCBI) compare
b0014 dnaK -0.6 -1.1 molecular chaperone DnaK (NCBI) compare
b3236 mdh -0.6 -3.1 malate dehydrogenase (NCBI) compare
b2252 ais -0.5 -2.1 hypothetical protein (NCBI) compare
b0888 trxB -0.5 -1.9 thioredoxin reductase, FAD/NAD(P)-binding (NCBI) compare
b1773 ydjI -0.5 -1.2 predicted aldolase (NCBI) compare
b3426 glpD -0.5 -1.4 sn-glycerol-3-phosphate dehydrogenase, aerobic, FAD/NAD(P)-binding (NCBI) compare
b1531 marA -0.5 -1.7 multiple antibiotic resistance; transcriptional activator of defense systems (VIMSS) compare
b1536 ydeI -0.5 -0.6 hypothetical protein (NCBI) compare
b1855 lpxM -0.5 -2.2 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase (NCBI) compare
b1728 ydjM -0.5 -1.5 predicted inner membrane protein regulated by LexA (RefSeq) compare
b1726 yniB -0.5 -1.3 predicted inner membrane protein (NCBI) compare
b1167 ymgC -0.5 -0.3 hypothetical protein (NCBI) compare
b2352 yfdI -0.5 -0.5 CPS-53 (KpLE1) prophage; predicted inner membrane protein (NCBI) compare
b4418 sraB -0.5 -1.3 unknown RNA (NCBI) compare
b4529 ydbJ -0.5 -0.7 hypothetical protein (NCBI) compare
b0310 ykgH -0.5 -0.6 predicted inner membrane protein (NCBI) compare
b3226 yhcK -0.5 -2.6 putative FADA-type transcriptional regulator (VIMSS) compare
b4648 ysaC -0.5 -1.8 no description compare
b1121 ycfZ -0.5 -1.0 predicted inner membrane protein (NCBI) compare
b4568 ytjA -0.5 -1.3 predicted protein (RefSeq) compare
b2498 upp -0.5 -1.1 uracil phosphoribosyltransferase (VIMSS) compare
b0949 uup -0.5 -3.1 fused predicted transporter subunits of ABC superfamily: ATP-binding components (NCBI) compare
b0386 proC -0.5 -2.2 pyrroline-5-carboxylate reductase (NCBI) compare
b1259 yciG -0.5 -1.1 orf, hypothetical protein (VIMSS) compare
b4653 yicT -0.5 -1.0 no description compare
b3261 fis -0.5 -0.9 DNA-binding protein Fis (NCBI) compare
b0605 ahpC -0.5 -2.1 alkyl hydroperoxide reductase, C22 subunit (NCBI) compare
b4172 hfq -0.5 -0.5 RNA-binding protein Hfq (NCBI) compare


Specific Phenotypes

For 4 genes in this experiment