Experiment set18IT016 for Pseudomonas putida KT2440

Compare to:

Temperature shift 30_to_25; with MOPS

200 most important genes:

  gene name fitness t score description  
PP_4890 -7.4 -5.1 ATP phosphoribosyltransferase regulatory subunit compare
PP_0422 -6.9 -4.8 Indole-3-glycerol phosphate synthase compare
PP_3511 -6.8 -4.7 Branched-chain-amino-acid aminotransferase compare
PP_1079 -6.7 -4.6 Ornithine carbamoyltransferase compare
PP_1988 -6.6 -4.6 3-isopropylmalate dehydrogenase compare
PP_2341 -6.4 -3.0 6-carboxy-5,6,7,8-tetrahydropterin synthase compare
PP_1231 -6.4 -4.4 quinolinate synthase [4Fe-4S] cluster subunit compare
PP_5303 -6.3 -4.4 aminoacrylate/iminopropionate hydrolase/deaminase compare
PP_1985 -6.2 -4.3 3-isopropylmalate dehydratase large subunit compare
PP_4829 -6.2 -4.0 putative precorrin-3B synthase compare
PP_0293 -6.2 -2.8 Imidazole glycerol phosphate synthase subunit HisF compare
PP_0290 -6.1 -4.2 Imidazole glycerol phosphate synthase subunit HisH compare
PP_4680 -6.0 -12.8 acetohydroxybutanoate synthase / acetolactate synthase compare
PP_4678 -6.0 -14.0 Ketol-acid reductoisomerase compare
PP_0420 -6.0 -12.1 aminodeoxychorismate synthase / para-aminobenzoate synthase multi-enzyme complex compare
PP_0967 -5.9 -11.4 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
PP_5097 -5.9 -13.2 homoserine O-acetyltransferase compare
PP_0965 -5.9 -11.3 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
PP_5185 -5.8 -4.0 acetylglutamate kinase-like protein (regulatory domain)/amino acid N-acetyltransferase compare
PP_2371 -5.7 -3.9 Sulphite reductase hemoprotein, beta subunit compare
PP_0082 -5.5 -3.8 tryptophan synthase alpha chain compare
PP_0184 -5.5 -3.8 Argininosuccinate lyase compare
PP_0289 -5.5 -8.3 Imidazoleglycerol-phosphate dehydratase compare
PP_2370 -5.4 -3.5 conserved protein of unknown function compare
PP_5582 -5.4 -1.4 conserved protein of unknown function compare
PP_0083 -5.3 -3.7 tryptophan synthase beta chain compare
PP_5289 -5.3 -3.7 Acetylglutamate kinase compare
PP_5347 -5.3 -9.5 pyruvate carboxylase subunit A compare
PP_2168 -5.2 -13.0 Transaldolase compare
PP_0966 -5.1 -11.3 Histidinol dehydrogenase compare
PP_2327 -5.1 -3.5 transcriptional dual regulator / CysB-O-acetyl-L-serine compare
PP_1088 -5.1 -10.9 Argininosuccinate synthase compare
PP_0417 -5.0 -17.0 Anthranilate synthase component 1 compare
PP_0421 -4.8 -8.0 Anthranilate phosphoribosyltransferase compare
PP_2001 -4.8 -8.4 O-succinylhomoserine sulfhydrylase compare
PP_0362 -4.7 -11.8 Biotin synthase compare
PP_5017 -4.7 -1.3 Sec-independent protein translocase protein TatB compare
PP_5014 -4.5 -3.1 Phosphoribosyl-AMP cyclohydrolase compare
PP_1995 -4.5 -8.0 N-(5'-phosphoribosyl)anthranilate isomerase compare
PP_5155 -4.4 -4.9 D-3-phosphoglycerate dehydrogenase / alpha-ketoglutarate reductase compare
PP_4561 -4.4 -1.2 stress response protein compare
PP_3999 -4.4 -3.0 Uroporphyrinogen-III C-methyltransferase/Precorrin-2 dehydrogenase/Sirohydrochlorin ferrochelatase compare
PP_5346 -4.3 -7.5 pyruvate carboxylase subunit B compare
PP_0735 -4.3 -1.6 molybdopterin-synthase adenylyltransferase compare
PP_4696 -4.3 -4.1 Nitrogen regulation protein NR(I) compare
PP_4909 -4.1 -6.9 phosphoserine phosphatase compare
PP_2581 -4.1 -1.5 conserved protein of unknown function compare
PP_2328 -4.0 -6.7 Phosphoadenosine phosphosulfate reductase compare
PP_5128 -4.0 -7.2 Dihydroxy-acid dehydratase compare
PP_5348 -4.0 -7.7 Transcriptional regulator, LysR family compare
PP_2390 -4.0 -7.1 Transcriptional regulator, LysR family compare
PP_4679 -3.9 -6.2 acetohydroxybutanoate synthase / acetolactate synthase compare
PP_5393 -3.6 -1.3 putative metal-binding chaperone compare
PP_2402 -3.6 -2.5 putative Sensor histidine kinase compare
PP_5098 -3.5 -5.6 methionine biosynthesis protein MetW compare
PP_4122 -3.5 -2.1 proton-pumping NADH:ubiquinone oxidoreductase, respiratory complex I, subunit E compare
PP_4699 -3.5 -5.5 3-methyl-2-oxobutanoate hydroxymethyltransferase compare
PP_0065 -3.4 -3.3 NAD-binding component of TrK potassium transporter compare
PP_0292 -3.3 -2.5 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
PP_5015 -3.3 -3.0 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
PP_5350 -3.2 -4.4 Transcriptional regulator, RpiR family compare
PP_4984 -3.2 -6.7 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase compare
PP_0363 -3.2 -7.5 8-amino-7-oxononanoate synthase compare
PP_4922 -3.2 -7.7 Phosphomethylpyrimidine synthase compare
PP_1233 -3.1 -3.6 sulfurtransferase compare
PP_0365 -3.0 -6.3 Malonyl-[acyl-carrier protein] O-methyltransferase compare
PP_1986 -3.0 -3.2 3-isopropylmalate dehydratase small subunit compare
PP_1025 -3.0 -7.7 2-isopropylmalate synthase compare
PP_1268 -3.0 -2.0 putative HtrA suppressor protein sohA compare
PP_1679 -2.8 -2.3 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase compare
PP_1672 -2.8 -4.4 cob(I)alamin adenolsyltransferase/cobinamide ATP-dependent adenolsyltransferase compare
PP_4977 -2.8 -7.9 5,10-methylenetetrahydrofolate reductase compare
PP_1048 -2.8 -2.4 putative protein secretion protein for export compare
PP_4804 -2.7 -4.0 RlpA-like lipoprotein compare
PP_1994 -2.6 -2.5 tRNA pseudouridine (38-40)synthase compare
PP_4782 -2.6 -3.3 Phosphomethylpyrimidine kinase compare
PP_1678 -2.6 -2.3 bifunctional cobinamide-P guanylyltransferase - adenosylcobinamide kinase compare
PP_1677 -2.6 -4.3 Adenosyl-cobyric acid synthase compare
PP_0291 -2.5 -2.6 conserved protein of unknown function compare
PP_5104 -2.5 -4.5 thiazole synthase compare
PP_2898 -2.4 -1.8 conserved exported protein of unknown function compare
PP_1362 -2.4 -3.6 pyruvate kinase II compare
PP_4271 -2.4 -1.1 conserved protein of unknown function compare
PP_2378 -2.3 -3.3 Fe/S biogenesis protein NfuA compare
PP_0366 -2.3 -3.6 dethiobiotin synthetase compare
PP_1912 -2.2 -4.5 Phosphate acyltransferase compare
PP_1426 -2.2 -6.4 L-aspartate oxidase compare
PP_3790 -2.2 -5.6 diaminopimelate epimerase compare
PP_4480 -2.2 -6.0 arginine N-succinyltransferase, subunit alpha compare
PP_1675 -2.2 -5.8 Subunit of adenosylcobinamide-phosphate synthase beta component compare
PP_3507 -2.2 -6.3 Aerobic cobaltochelatase subunit CobN compare
PP_0364 -2.1 -4.6 pimeloyl-[acp] methyl ester esterase compare
PP_1681 -2.1 -6.3 cobalamin 5'-phosphate synthase / Cobalamin synthase compare
PP_4830 -2.1 -3.9 precorrin-6Y C(5,15)-methyltransferase compare
PP_2375 -2.1 -8.0 cobalamin-dependent methionine synthase compare
PP_4700 -2.1 -1.4 pantothenate synthetase compare
PP_4824 -2.0 -6.1 Sensor histidine kinase/response regulator compare
PP_0164 -2.0 -4.8 conserved protein of unknown function compare
PP_4832 -2.0 -2.5 Precorrin-6x reductase compare
PP_1022 -2.0 -3.2 glucose 6-phosphate-1-dehydrogenase compare
PP_1303 -2.0 -4.5 Sulfate adenylyltransferase subunit 2 compare
PP_5448 -2.0 -2.6 conserved protein of unknown function compare
PP_4902 -2.0 -2.1 Oligoribonuclease compare
PP_1366 -2.0 -1.1 Transcriptional regulator MvaT, P16 subunit compare
PP_2388 -2.0 -2.8 Transporter, LysE family compare
PP_5095 -2.0 -1.0 pyrroline-5-carboxylate reductase compare
PP_5203 -1.9 -3.6 5-formyltetrahydrofolate cyclo-ligase compare
PP_2313 -1.9 -2.2 conserved membrane protein of unknown function compare
PP_1892 -1.9 -1.4 conserved protein of unknown function compare
PP_4262 -1.9 -1.8 Cytochrome oxidase maturation protein, cbb3-type compare
PP_5495 -1.9 -1.5 protein of unknown function compare
PP_0547 -1.8 -5.8 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase compare
PP_4828 -1.7 -1.4 Precorrin-8X methylmutase compare
PP_5500 -1.7 -1.9 protein of unknown function compare
PP_1664 -1.7 -2.5 phosphoribosylglycinamide formyltransferase 1 compare
PP_1439 -1.7 -1.6 conserved exported protein of unknown function compare
PP_4827 -1.7 -5.4 Precorrin-2 C(20)-methyltransferase compare
PP_4124 -1.7 -3.9 NADH-quinone oxidoreductase subunit G compare
PP_2403 -1.6 -1.2 Chemotaxis protein CheY compare
PP_3328 -1.6 -1.4 putative Ring-cleaving dioxygenase compare
PP_2336 -1.6 -3.8 aconitate hydratase 1 compare
PP_4273 -1.6 -1.4 Transcriptional regulator, MerR family compare
PP_0787 -1.6 -1.6 quinolinate phosphoribosyltransferase (decarboxylating) monomer compare
PP_4338 -1.6 -4.6 Chemotaxis histidine kinase CheA compare
PP_1304 -1.6 -4.5 sulfate adenylyltransferase subunit 1/adenylyl-sulfate kinase compare
PP_5475 -1.6 -1.0 conserved protein of unknown function compare
PP_1348 -1.6 -3.7 putative MutT/nudix family protein/thiamine-phosphate pyrophosphorylase compare
PP_2232 -1.6 -1.8 XRE family transcriptional regulator compare
PP_2530 -1.6 -1.6 conserved protein of unknown function compare
PP_3649 -1.6 -2.4 Transcriptional regulator, GntR family compare
PP_0393 -1.5 -1.1 putative 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase compare
PP_5022 -1.5 -1.5 Glutamine transport ATP-binding protein GlnQ compare
PP_3365 -1.5 -1.0 Acetolactate synthase compare
PP_4004 -1.5 -2.4 DNA translocase FtsK compare
PP_1917 -1.5 -4.1 4-amino-4-deoxychorismate lyase compare
PP_2088 -1.5 -1.8 RNA polymerase sigma factor SigX compare
PP_2253 -1.5 -2.3 Transcriptional regulator, GntR family compare
PP_4471 -1.5 -3.2 Magnesium transporter compare
PP_3417 -1.5 -2.3 D-gluconate transporter compare
PP_4964 -1.5 -2.7 D-erythrose 4-phosphate dehydrogenase compare
PP_3241 -1.5 -1.2 conserved exported protein of unknown function compare
PP_1009 -1.4 -2.5 glyceraldehyde-3-phosphate dehydrogenase compare
PP_1673 -1.4 -3.3 cobyrinate a,c-diamide synthase compare
PP_4364 -1.4 -3.0 putative Anti-sigma F factor antagonist compare
PP_1000 -1.4 -2.8 ornithine carbamoyltransferase, catabolic compare
PP_4785 -1.4 -3.9 conserved exported protein of unknown function compare
PP_0232 -1.4 -1.0 ATP-binding taurine transporter subunit compare
PP_3946 -1.4 -1.1 HTH-type transcriptional repressor NicR compare
PP_0685 -1.4 -1.8 conserved protein of unknown function compare
PP_3906 -1.4 -2.3 conserved protein of unknown function compare
PP_1381 -1.4 -1.0 4-carboxymuconolactone decarboxylase compare
PP_1898 -1.4 -2.8 MotA/TolQ/ExbB proton channel family protein compare
PP_3277 -1.4 -3.5 ring 1,2-phenylacetyl-CoA epoxidase regulatory subunit compare
PP_1198 -1.4 -2.1 transcriptional regulator, Cro/CI family (higA antitoxin like) compare
PP_4482 -1.4 -2.1 Transcriptional regulator, AraC family compare
PP_0122 -1.4 -1.2 conserved exported protein of unknown function compare
PP_1654 -1.4 -1.8 cysteine synthase B compare
PP_3938 -1.4 -1.0 conserved protein of unknown function compare
PP_1878 -1.3 -3.2 conserved protein of unknown function conserved
PP_2878 -1.3 -1.5 conserved protein of unknown function compare
PP_4546 -1.3 -3.2 ATP-dependent helicase HrpA compare
PP_4392 -1.3 -4.2 chemotaxis protein methyltransferase compare
PP_2302 -1.3 -3.7 DNA-binding, ATP-dependent protease compare
PP_1041 -1.3 -1.7 twin arginine protein export complex subunit compare
PP_5328 -1.3 -1.4 putative phosphate transport system permease protein compare
PP_4479 -1.3 -2.3 arginine N-succinyltransferase, subunit beta compare
PP_4126 -1.2 -1.4 NADH-quinone oxidoreductase subunit I compare
PP_4739 -1.2 -2.1 conserved protein of unknown function compare
PP_4693 -1.2 -3.5 RNA polymerase-binding transcription factor DksA compare
PP_2820 -1.2 -2.3 HTH-type transcriptional regulator nfxB compare
PP_1128 -1.2 -2.2 OmpA family protein compare
PP_2442 -1.2 -1.6 conserved protein of unknown function, DUF480 family compare
PP_1770 -1.2 -1.4 3-phosphoshikimate 1-carboxyvinyltransferase compare
PP_0833 -1.2 -0.8 queuine tRNA-ribosyltransferase compare
PP_4826 -1.2 -3.0 Precorrin-3B C17-methyltransferase compare
PP_0719 -1.2 -0.7 ribosome-associated potassium-dependent informational ATP/GTPase compare
PP_2970 -1.2 -1.3 conserved exported protein of unknown function compare
PP_3539 -1.1 -1.3 putative Transcriptional regulator compare
PP_0846 -1.1 -0.7 DnaK-like molecular chaperone specific for IscU compare
PP_5075 -1.1 -5.2 glutamate synthase (NADPH) beta subunit compare
PP_4199 -1.1 -0.8 putative Lipoprotein compare
PP_0575 -1.1 -2.4 conserved membrane protein of unknown function compare
PP_1834 -1.1 -2.4 conserved protein of unknown function compare
PP_4131 -1.1 -3.4 NADH-quinone oxidoreductase subunit N compare
PP_4917 -1.1 -2.2 3',5'-cyclic-nucleotide phosphodiesterase compare
PP_2032 -1.1 -2.5 putative ATPase compare
PP_5639 -1.1 -4.0 conserved exported protein of unknown function compare
PP_4477 -1.1 -3.2 N-succinylarginine dihydrolase compare
PP_1589 -1.1 -3.7 uridylyltransferase compare
PP_5514 -1.1 -1.2 conserved protein of unknown function compare
PP_3105 -1.1 -1.8 conserved membrane protein of unknown function compare
PP_0949 -1.1 -2.3 putative ATP-binding protein UPF0042 compare
PP_4591 -1.1 -1.7 Ribonuclease D compare
PP_1224 -1.1 -2.9 periplasmic subunit of the TolQRA transport system compare
PP_5106 -1.1 -1.9 conserved inner membrane protein compare
PP_4340 -1.1 -1.1 response regulator for chemotactic signal transduction compare
PP_5073 -1.1 -1.3 conserved exported protein of unknown function compare
PP_5331 -1.0 -1.8 Long-chain acyl-CoA thioester hydrolase compare
PP_1055 -1.0 -0.6 Type II secretion pathway protein GspN compare
PP_4662 -1.0 -1.5 conserved protein of unknown function compare


Specific Phenotypes

For 3 genes in this experiment

For temperature shift D-Glucose in Pseudomonas putida KT2440

For temperature shift D-Glucose across organisms