Experiment set16IT021 for Pseudomonas putida KT2440

Compare to:

L-Isoleucine carbon source

200 most detrimental genes:

  gene name fitness t score description  
PP_1623 +3.1 26.7 RNA polymerase, sigma S (sigma 38) factor compare
PP_1650 +3.1 27.7 Sensor protein GacS compare
PP_4099 +3.1 29.4 two-componenent system BarA/UvrY - regulatory subunit compare
PP_2387 +2.5 12.0 conserved protein of unknown function compare
PP_1898 +2.2 12.8 MotA/TolQ/ExbB proton channel family protein compare
PP_4171 +2.2 13.4 conserved exported protein of unknown function compare
PP_5053 +2.1 8.3 Protein-export protein SecB compare
PP_4994 +2.1 14.1 conserved protein of unknown function compare
PP_2889 +1.8 7.2 putative Transmembrane regulator PrtR compare
PP_2389 +1.6 10.8 conserved protein of unknown function compare
PP_5232 +1.6 7.2 conserved protein of unknown function compare
PP_4754 +1.5 11.8 Transcriptional regulator, TetR family compare
PP_4947 +1.5 13.4 proline dehydrogenase/1-pyrroline-5-carboxylate dehydrogenase conserved
PP_4880 +1.4 10.4 exoribonuclease R compare
PP_3821 +1.4 10.9 UTP-glucose-1-phosphate uridylyltransferase compare
PP_2390 +1.4 9.3 Transcriptional regulator, LysR family compare
PP_5331 +1.4 4.9 Long-chain acyl-CoA thioester hydrolase compare
PP_1778 +1.3 6.9 Lipopolysaccharide ABC export system, permease protein compare
PP_1779 +1.2 7.1 Lipopolysaccharide ABC export system, ATP-binding protein compare
PP_0168 +1.2 11.1 putative surface adhesion protein compare
PP_0674 +1.1 9.7 ADP/ATP ratio sensor and inhibitor of translation compare
PP_2388 +1.1 5.6 Transporter, LysE family compare
PP_0166 +1.1 10.2 HlyD family secretion protein compare
PP_4938 +1.1 7.5 putative Glycosyl transferase compare
PP_0833 +1.1 3.2 queuine tRNA-ribosyltransferase compare
PP_4519 +1.1 9.4 Agglutination protein compare
PP_0167 +1.1 9.8 Toxin secretion ATP-binding protein compare
PP_0165 +1.0 9.2 GGDEF domain protein compare
PP_2144 +1.0 3.8 Transcriptional regulator, TetR family compare
PP_4173 +0.9 6.3 Sensor histidine kinase/response regulator compare
PP_4697 +0.9 3.3 poly(A) polymerase compare
PP_0959 +0.9 3.4 phospholipid ABC transporter compare
PP_0185 +0.9 6.8 Positive alginate biosynthesis regulatory protein compare
PP_4785 +0.8 5.6 conserved exported protein of unknown function compare
PP_0339 +0.8 4.9 Pyruvate dehydrogenase E1 component compare
PP_4936 +0.8 5.2 O-antigen polymerase compare
PP_4479 +0.8 4.1 arginine N-succinyltransferase, subunit beta compare
PP_4940 +0.8 5.4 Putative glycosyltransferase compare
PP_4529 +0.8 3.0 conserved protein of unknown function compare
PP_4484 +0.8 6.8 histidine / lysine / arginine / ornithine ABC transporter - permease subunit compare
PP_4820 +0.8 5.3 tRNA-dihydrouridine synthase B compare
PP_1776 +0.8 7.2 Mannose-6-phosphate isomerase/mannose-1-phosphate guanylyltransferase compare
PP_1780 +0.8 7.1 putative mannosyltransferase compare
PP_1236 +0.7 3.2 putative Glycine cleavage system transcriptional repressor compare
PP_4622 +0.7 3.2 Hmg transcriptional repressor compare
PP_4942 +0.7 2.3 conserved protein of unknown function compare
PP_3580 +0.7 2.4 conserved protein of unknown function compare
PP_1799 +0.7 6.3 GDP-mannose 4,6-dehydratase compare
PP_1310 +0.7 2.0 conserved hypothetical protein compare
PP_4199 +0.7 1.3 putative Lipoprotein compare
PP_4204 +0.7 3.4 antitoxin of the type II toxin-antitoxin MqsRA system and DNA-binding transcriptional repressor compare
PP_1568 +0.7 1.6 conserved protein of unknown function compare
PP_5429 +0.7 3.6 protein of unknown function compare
PP_2575 +0.7 2.1 conserved exported protein of unknown function compare
PP_4787 +0.7 2.8 putative protein with nucleoside triphosphate hydrolase domain compare
PP_3481 +0.7 2.6 conserved exported protein of unknown function compare
PP_1575 +0.7 2.3 conserved protein of unknown function compare
PP_0191 +0.7 2.9 Transcriptional regulatory protein AlgQ compare
PP_0697 +0.6 5.0 ribosomal-protein-S18-alanine N-acetyltransferase compare
PP_4342 +0.6 2.0 flagellar synthesis regulator, putative ATPase compare
PP_1635 +0.6 2.0 DNA-binding response regulator compare
PP_5223 +0.6 2.9 regulator of nucleotide diphosphokinase compare
PP_1214 +0.6 2.3 putative transcriptional regulatory protein compare
PP_2765 +0.6 1.0 putative Sulfonate monooxygenase MsuD compare
PP_4133 +0.6 2.3 Transcriptional regulator-related protein compare
PP_4363 +0.6 4.3 Sensor histidine kinase/response regulator compare
PP_t29 +0.6 1.0 tRNA-Ala compare
PP_1269 +0.6 1.3 Universal stress protein family compare
PP_4486 +0.6 4.2 lysine / arginine / ornithine ABC transporter - periplasmic binding protein compare
PP_2147 +0.6 2.5 conserved exported protein of unknown function compare
PP_4944 +0.6 2.6 Carbamoyltransferase compare
PP_1979 +0.6 2.4 putative Hydrolase compare
PP_5533 +0.6 1.3 conserved protein of unknown function compare
PP_1805 +0.6 5.4 Polysaccharide biosynthesis protein compare
PP_2457 +0.6 4.2 DNA-binding transcriptional repressor compare
PP_4957 +0.6 2.5 conserved protein of unknown function compare
PP_4050 +0.6 5.0 glycogen synthase compare
PP_4930 +0.6 3.1 putative small multidrug resistance protein compare
PP_0306 +0.6 1.3 conserved protein of unknown function compare
PP_1801 +0.6 4.8 Glycosyl transferase WbpY compare
PP_2107 +0.6 1.9 conserved protein of unknown function compare
PP_4262 +0.6 1.7 Cytochrome oxidase maturation protein, cbb3-type compare
PP_4172 +0.6 3.2 conserved exported protein of unknown function compare
PP_4483 +0.5 3.6 histidine lysine / arginine / ornithine ABC transporter - ATP binding subunit compare
PP_1804 +0.5 4.4 Glycosyl transferase WbpL compare
PP_t12 +0.5 1.1 tRNA-Thr compare
PP_0003 +0.5 2.0 16S RNA methyltransferase compare
PP_1930 +0.5 1.8 arsenic resistance transcriptional regulator compare
PP_4959 +0.5 4.0 diguanylate cyclase compare
PP_1544 +0.5 2.0 conserved protein of unknown function compare
PP_2716 +0.5 2.3 arsenate reductase compare
PP_4485 +0.5 3.8 histidine / lysine / arginine / ornithine ABC transporter - permease subunit compare
PP_1453 +0.5 4.1 putative NUDIX hydrolase with low 3-phosphohydroxypyruvate phosphatase activity compare
PP_1800 +0.5 4.0 Oxidoreductase Rmd compare
PP_0856 +0.5 2.0 conserved lipoprotein of unknown function compare
PP_3020 +0.5 2.4 putative Serine/threonine protein phosphatase compare
PP_2163 +0.5 3.0 VacJ lipoprotein compare
PP_5093 +0.5 1.2 twitching motility protein compare
PP_5038 +0.5 2.3 conserved lipoprotein of unknown function compare
PP_1663 +0.5 3.9 conserved exported protein of unknown function compare
PP_0725 +0.5 2.8 conserved hypothetical TPR repeat protein compare
PP_1802 +0.5 4.4 glycosyl transferase compare
PP_4100 +0.5 2.2 Transcriptional regulator, Cro/CI family compare
PP_3967 +0.5 2.3 MutT/nudix family protein compare
PP_3043 +0.5 1.0 conserved protein of unknown function compare
PP_2385 +0.5 3.0 Branched-chain amino acid transport protein AzlC compare
PP_4720 +0.5 1.9 putative RNA binding protein compare
PP_5496 +0.5 2.2 conserved exported protein of unknown function compare
PP_2437 +0.5 3.2 putative Acyl-CoA dehydrogenase compare
PP_2220 +0.5 2.2 C4-type zinc finger protein, DksA/TraR family compare
PP_3761 +0.5 3.9 Sensor histidine kinase/response regulator compare
PP_1113 +0.5 3.7 Pyridoxal-phosphate dependent enzyme family protein compare
PP_2459 +0.5 1.5 ribose pyranase compare
PP_3191 +0.5 2.7 putative threonine ammonia-lyase / dehydratase compare
PP_0958 +0.5 2.5 phospholipid ABC transporter ATP-binding subunit compare
PP_2499 +0.5 1.0 conserved protein of unknown function compare
PP_4136 +0.5 1.1 Transcriptional regulator, LuxR family compare
PP_0761 +0.5 3.0 Ribosomal RNA small subunit methyltransferase C compare
PP_5633 +0.5 1.5 conserved protein of unknown function compare
PP_1917 +0.5 3.0 4-amino-4-deoxychorismate lyase compare
PP_2082 +0.5 3.8 phosphoenolpyruvate synthetase compare
PP_2903 +0.5 1.7 peptidyl-prolyl cis-trans isomerase B (rotamase B) compare
PP_2513 +0.5 1.8 4-oxalomesaconate tautomerase compare
PP_1109 +0.4 3.7 Transcriptional regulator, GntR family compare
PP_4710 +0.4 3.6 tRNA pseudouridine 55 synthase compare
PP_4499 +0.4 1.8 putative maturation enzyme compare
PP_4225 +0.4 2.2 two component system DNA-binding transcriptional activator QseB compare
PP_1803 +0.4 3.7 UDP-sugar epimerase compare
PP_2247 +0.4 1.3 putative Endoribonuclease compare
PP_5324 +0.4 1.6 Response regulator compare
PP_1041 +0.4 0.7 twin arginine protein export complex subunit compare
PP_5160 +0.4 3.1 conserved exported protein of unknown function compare
PP_2958 +0.4 2.1 Glutaredoxin compare
PP_4340 +0.4 2.1 response regulator for chemotactic signal transduction compare
PP_2668 +0.4 0.9 ABC efflux transporter, ATP-binding protein compare
PP_0864 +0.4 3.6 ornithine decarboxylase compare
PP_0202 +0.4 1.8 CBS domain-containing protein compare
PP_1777 +0.4 3.5 phosphomannomutase compare
PP_4424 +0.4 1.4 Uncharacterized HTH-type transcriptional regulator y4tD compare
PP_1325 +0.4 2.7 putative lipoprotein compare
PP_3509 +0.4 1.5 Glyoxalase family protein compare
PP_3522 +0.4 1.9 conserved protein of unknown function compare
PP_2760 +0.4 2.4 putative ribose transport permease protein compare
PP_1268 +0.4 1.3 putative HtrA suppressor protein sohA compare
PP_2101 +0.4 1.7 DNA-binding response regulator in two-component regulatory system with EvgS compare
PP_1074 +0.4 1.6 DNA-binding transcriptional repressor - GlpR-glycerol-3-phosphate compare
PP_1632 +0.4 1.3 conserved protein of unknown function compare
PP_2231 +0.4 1.1 putative permease of the drug/metabolite transporter (DMT) superfamily compare
PP_5594 +0.4 1.5 conserved protein of unknown function compare
PP_2458 +0.4 3.0 ribokinase compare
PP_1537 +0.4 1.7 conserved protein of unknown function compare
PP_1824 +0.4 0.9 Smr domain protein compare
PP_2503 +0.4 1.7 putative 3-oxoacyl-(Acyl-carrier-protein) reductase compare
PP_1007 +0.4 2.7 putative Transmembrane sensor compare
PP_1048 +0.4 1.4 putative protein secretion protein for export compare
PP_5549 +0.4 2.3 conserved protein of unknown function compare
PP_4817 +0.4 1.6 MaoC domain protein compare
PP_4980 +0.4 2.8 ATP-dependent RNA helicase compare
PP_1208 +0.4 1.3 conserved protein of unknown function, SlyX family compare
PP_3098 +0.4 0.9 conserved protein of unknown function compare
PP_4835 +0.4 1.6 conserved exported protein of unknown function compare
PP_3110 +0.4 1.3 protein of unknown function compare
PP_5667 +0.4 1.7 putative microcin B17-like-processing protein, McbC family compare
PP_4575 +0.4 1.4 Urea amidolyase-related protein compare
PP_0258 +0.4 1.5 regulator of murein cross-linking compare
PP_2311 +0.4 1.5 Mg-dependent cytoplasmic DNase / RNase compare
PP_5490 +0.4 2.2 site-specific DNA recombinase compare
PP_3122 +0.4 2.4 acetoacetyl CoA-transferase (subunit A) compare
PP_1142 +0.4 0.8 conserved protein of unknown function compare
PP_5058 +0.4 1.9 Carboxy-terminal-processing protease compare
PP_2510 +0.4 0.7 conserved protein of unknown function compare
PP_1356 +0.4 2.2 conserved protein of unknown function compare
PP_4349 +0.4 1.9 conserved protein of unknown function compare
PP_1352 +0.4 1.4 UPF0234 protein PP_1352 compare
PP_3357 +0.4 1.7 p-hydroxybenzaldehyde dehydrogenase vdh (EC 1.2.1.64) (from data) compare
PP_2884 +0.4 2.6 XRE family transcriptional regulator compare
PP_2383 +0.4 1.7 Transcriptional regulator, AraC family compare
PP_1004 +0.4 1.6 conserved protein of unknown function compare
PP_5532 +0.4 1.8 conserved protein of unknown function compare
PP_3971 +0.4 1.0 conserved protein of unknown function compare
PP_1854 +0.4 2.4 conserved protein of unknown function compare
PP_0961 +0.4 2.5 toluene tolerance protein compare
PP_5283 +0.4 2.3 periplasmic dipeptide transport protein compare
PP_0692 +0.4 2.3 conserved protein of unknown function compare
PP_3891 +0.4 1.2 conserved protein of unknown function compare
PP_2826 +0.4 1.8 Transcriptional regulator MexT compare
PP_4669 +0.4 1.4 OmpA family protein compare
PP_5279 +0.4 1.0 conserved protein of unknown function compare
PP_3908 +0.4 0.9 conserved protein of unknown function compare
PP_1523 +0.4 1.7 conserved protein of unknown function compare
PP_4449 +0.4 1.8 conserved protein of unknown function compare
PP_0682 +0.4 1.4 conserved inner membrane protein of unknown function, UPF0114 family compare
PP_5500 +0.4 1.4 protein of unknown function compare
PP_2441 +0.4 1.1 conserved protein of unknown function compare
PP_3643 +0.4 1.5 putative Oxidoreductase compare
PP_2729 +0.4 1.8 conserved protein of unknown function compare
PP_4253 +0.4 1.5 cytochrome c oxidase subunit, cbb3-type compare
PP_5491 +0.3 1.3 conserved protein of unknown function with SEC-C motif domain compare
PP_2939 +0.3 1.8 toxin of the YefM-YoeB antitoxin/toxin complex and DNA-binding transcriptional repressor compare
PP_0921 +0.3 1.7 Transcriptional regulator, ArsR family compare


Specific Phenotypes

For 27 genes in this experiment

For carbon source L-Isoleucine in Pseudomonas putida KT2440

For carbon source L-Isoleucine across organisms