Experiment set16IT007 for Escherichia coli BW25113

Compare to:

LB_plus_SM_buffer

200 most important genes:

  gene name fitness t score description  
b1192 ldcA -3.5 -10.8 L,D-carboxypeptidase A (NCBI) compare
b3979 thrT -2.4 -1.0 tRNA-Thr (NCBI) compare
b2642 yfjW -2.4 -2.2 CP4-57 prophage; predicted inner membrane protein (NCBI) compare
b3613 yibP -2.1 -6.7 putative membrane protein (VIMSS) compare
b1286 rnb -2.0 -4.1 exoribonuclease II (NCBI) compare
b0149 mrcB -2.0 -13.4 penicillin-binding protein 1b (NCBI) compare
b1882 cheY -1.9 -1.3 chemotaxis regulator transmitting signal to flagellar motor component (NCBI) compare
b3021 ygiT -1.8 -4.4 predicted DNA-binding transcriptional regulator (NCBI) compare
b4042 dgkA -1.8 -3.4 diacylglycerol kinase (NCBI) compare
b2830 nudH -1.7 -2.0 dinucleoside polyphosphate hydrolase (NCBI) compare
b2699 recA -1.7 -1.6 recombinase A (NCBI) compare
b2318 truA -1.6 -3.2 tRNA pseudouridine synthase A (NCBI) compare
b4414 tff -1.6 -4.1 unknown RNA (NCBI) compare
b1290 sapF -1.6 -2.1 predicted antimicrobial peptide transporter subunit (NCBI) compare
b1863 ruvC -1.5 -3.1 Holliday junction resolvase (NCBI) compare
b1861 ruvA -1.5 -2.1 Holliday junction DNA helicase motor protein (NCBI) compare
b0049 apaH -1.5 -4.0 diadenosinetetraphosphatase (NCBI) compare
b4146 yjeK -1.5 -3.5 predicted lysine aminomutase (NCBI) compare
b0740 tolB -1.5 -5.7 translocation protein TolB precursor (NCBI) compare
b3778 rep -1.5 -8.2 DNA helicase and single-stranded DNA-dependent ATPase (NCBI) compare
b3863 polA -1.5 -1.9 DNA polymerase I (NCBI) compare
b2528 iscA -1.5 -1.9 iron-sulfur cluster assembly protein (NCBI) compare
b3940 metL -1.5 -7.0 bifunctional aspartate kinase II/homoserine dehydrogenase II (NCBI) compare
b2498 upp -1.4 -3.7 uracil phosphoribosyltransferase (VIMSS) compare
b1105 ycfM -1.4 -4.1 predicted outer membrane lipoprotein (NCBI) compare
b4171 miaA -1.4 -4.9 tRNA delta(2)-isopentenylpyrophosphate transferase (NCBI) compare
b1545 pinQ -1.4 -0.5 Qin prophage; predicted site-specific recombinase (NCBI) compare
b2912 ygfA -1.4 -3.4 putative ligase (VIMSS) compare
b2904 gcvH -1.3 -2.8 glycine cleavage system protein H (NCBI) compare
b0890 ftsK -1.3 -5.1 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b3390 aroK -1.3 -2.8 shikimate kinase I (NCBI) compare
b3620 rfaF -1.3 -5.2 ADP-heptose:LPS heptosyltransferase II (NCBI) compare
b1160 elbA -1.3 -1.4 hypothetical protein (NCBI) compare
b2567 rnc -1.3 -1.2 ribonuclease III (NCBI) compare
b2935 tktA -1.3 -2.2 transketolase 1, thiamin-binding (NCBI) compare
b3169 nusA -1.3 -3.2 transcription elongation factor NusA (NCBI) compare
b2330 yfcB -1.3 -2.3 putative adenine-specific methylase (VIMSS) compare
b1292 sapC -1.2 -2.1 predicted antimicrobial peptide transporter subunit (NCBI) compare
b1860 ruvB -1.2 -1.1 Holliday junction DNA helicase B (NCBI) compare
b4375 prfC -1.2 -5.6 peptide chain release factor 3 (NCBI) compare
b0200 gmhB -1.2 -1.5 hypothetical protein (NCBI) compare
b4593 ymgI -1.2 -1.6 hypothetical protein (RefSeq) compare
b2853 ygeI -1.2 -0.7 hypothetical protein (NCBI) compare
b2820 recB -1.2 -0.8 exonuclease V (RecBCD complex), beta subunit (NCBI) compare
b3839 tatC -1.2 -6.0 TatABCE protein translocation system subunit (NCBI) compare
b3290 trkA -1.2 -2.8 potassium transporter peripheral membrane component (NCBI) compare
b3977 tyrU -1.1 -1.2 tRNA-Tyr (NCBI) compare
b0738 tolR -1.1 -3.0 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b0949 uup -1.1 -7.3 fused predicted transporter subunits of ABC superfamily: ATP-binding components (NCBI) compare
b4201 priB -1.1 -2.7 primosomal replication protein N (NCBI) compare
b0683 fur -1.1 -1.2 ferric uptake regulator (NCBI) compare
b0741 pal -1.1 -3.7 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b2576 srmB -1.1 -3.8 ATP-dependent RNA helicase (NCBI) compare
b4685 yrbN -1.1 -3.0 expressed protein (RefSeq) compare
b3741 gidA -1.1 -4.8 glucose-inhibited division protein A (NCBI) compare
b2620 smpB -1.0 -1.4 SsrA-binding protein (NCBI) compare
b3500 gor -1.0 -1.9 glutathione reductase (NCBI) compare
b0730 mngR -1.0 -1.9 DNA-binding transcriptional dual regulator, fatty-acyl-binding (NCBI) compare
b3387 dam -1.0 -7.6 DNA adenine methylase (NCBI) compare
b3619 rfaD -1.0 -3.3 ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) compare
b3026 qseC -1.0 -4.1 sensory histidine kinase in two-component regulatory system with QseB (NCBI) compare
b1524 yneH -1.0 -1.0 predicted glutaminase (NCBI) compare
b3706 trmE -0.9 -4.4 tRNA modification GTPase (NCBI) compare
b2518 ndk -0.9 -2.9 nucleoside diphosphate kinase (NCBI) compare
b3792 wzxE -0.9 -5.4 O-antigen translocase (NCBI) compare
b2947 gshB -0.9 -4.2 glutathione synthetase (NCBI) compare
b1724 ydiZ -0.9 -2.3 hypothetical protein (NCBI) compare
b0222 lpcA -0.9 -2.5 phosphoheptose isomerase (NCBI) compare
b4155 yjeA -0.9 -0.9 putative lysyl-tRNA synthetase (VIMSS) compare
b2343 b2343 -0.9 -1.6 orf, hypothetical protein (VIMSS) compare
b1679 sufE -0.8 -2.9 cysteine desufuration protein SufE (NCBI) compare
b3870 glnA -0.8 -3.1 glutamine synthetase (NCBI) compare
b4481 rffT -0.8 -5.1 4-alpha-L-fucosyltransferase (NCBI) compare
b3162 deaD -0.8 -4.1 inducible ATP-independent RNA helicase (VIMSS) compare
b0658 ybeX -0.8 -0.6 predicteed ion transport (NCBI) compare
b2808 gcvA -0.8 -3.5 DNA-binding transcriptional dual regulator (NCBI) compare
b3916 pfkA -0.8 -2.2 6-phosphofructokinase (NCBI) compare
b3791 rffA -0.8 -5.2 TDP-4-oxo-6-deoxy-D-glucose transaminase (NCBI) compare
b4163 glyV -0.8 -1.9 tRNA-Gly (NCBI) compare
b1877 yecT -0.8 -2.2 orf, hypothetical protein (VIMSS) compare
b1361 ydaW -0.8 -0.5 orf, hypothetical protein (VIMSS) compare
b1497 b1497 -0.8 -0.4 putative enzyme (VIMSS) compare
b1165 ymgA -0.8 -0.5 hypothetical protein (NCBI) compare
b1257 yciE -0.8 -0.4 hypothetical protein (NCBI) compare
b2569 lepA -0.8 -3.1 GTP-binding protein LepA (NCBI) compare
b3726 pstA -0.8 -4.1 phosphate transporter subunit (NCBI) compare
b3636 rpmG -0.8 -1.6 50S ribosomal protein L33 (NCBI) compare
b4603 rseX -0.8 -0.6 sRNA regulating ompA and ompC translation, with Hfq (RefSeq) compare
b0113 pdhR -0.8 -4.1 transcriptional regulator of pyruvate dehydrogenase complex (NCBI) compare
b1164 ycgZ -0.8 -1.5 hypothetical protein (NCBI) compare
b1628 rsxB -0.8 -3.1 electron transport complex protein RnfB (NCBI) compare
b3405 ompR -0.8 -3.2 osmolarity response regulator (NCBI) compare
b2822 recC -0.8 -3.6 exonuclease V (RecBCD complex), gamma chain (NCBI) compare
b0928 aspC -0.7 -5.3 aspartate aminotransferase, PLP-dependent (NCBI) compare
b3463 ftsE -0.7 -0.5 predicted transporter subunit: ATP-binding component of ABC superfamily (NCBI) compare
b1550 b1550 -0.7 -1.1 orf, hypothetical protein (VIMSS) compare
b4048 yjbM -0.7 -1.4 hypothetical protein (NCBI) compare
b2501 ppk -0.7 -4.7 polyphosphate kinase (NCBI) compare
b1103 ycfF -0.7 -1.0 orf, hypothetical protein (VIMSS) compare
b2597 yfiA -0.7 -1.7 cold shock protein associated with 30S ribosomal subunit (NCBI) compare
b0739 tolA -0.7 -2.3 cell envelope integrity inner membrane protein TolA (NCBI) compare
b3237 argR -0.7 -3.9 arginine repressor (NCBI) compare
b1576 ydfD -0.7 -0.3 Qin prophage; predicted protein (NCBI) compare
b1129 phoQ -0.7 -1.4 sensory histidine kinase in two-compoent regulatory system with PhoP (NCBI) compare
b1499 ydeO -0.7 -0.3 predicted DNA-binding transcriptional acfivator (NCBI) compare
b1551 b1551 -0.7 -0.3 orf, hypothetical protein (VIMSS) compare
b3414 gntY -0.7 -3.6 predicted gluconate transport associated protein (NCBI) compare
b2421 cysM -0.7 -3.5 cysteine synthase B (O-acetylserine sulfhydrolase B) (NCBI) compare
b0617 citD -0.7 -1.9 citrate lyase, acyl carrier (gamma) subunit (NCBI) compare
b0167 glnD -0.7 -2.9 PII uridylyl-transferase (NCBI) compare
b0623 cspE -0.7 -1.6 cold shock protein E (NCBI) compare
b1182 hlyE -0.7 -0.6 hemolysin E (VIMSS) compare
b3052 rfaE -0.7 -2.7 fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) compare
b1125 potB -0.7 -2.3 spermidine/putrescine ABC transporter membrane protein (NCBI) compare
b2007 yeeX -0.7 -1.7 conserved protein (RefSeq) compare
b2297 pta -0.7 -0.4 phosphate acetyltransferase (NCBI) compare
b3631 rfaG -0.7 -5.8 glucosyltransferase I (NCBI) compare
b1258 yciF -0.7 -1.0 hypothetical protein (NCBI) compare
b0888 trxB -0.7 -2.6 thioredoxin reductase, FAD/NAD(P)-binding (NCBI) compare
b0746 valZ -0.7 -1.4 tRNA-Val (NCBI) compare
b2894 xerD -0.7 -0.9 site-specific tyrosine recombinase XerD (NCBI) compare
b1001 yccE -0.7 -0.4 hypothetical protein (NCBI) compare
b0737 tolQ -0.7 -2.0 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b1409 ynbB -0.6 -1.0 predicted CDP-diglyceride synthase (NCBI) compare
b3261 fis -0.6 -1.6 DNA-binding protein Fis (NCBI) compare
b0191 yaeJ -0.6 -3.5 hypothetical protein (NCBI) compare
b1480 sra -0.6 -1.4 30S ribosomal subunit protein S22 (NCBI) compare
b1347 ydaC -0.6 -0.3 Rac prophage; predicted protein (NCBI) compare
b1961 dcm -0.6 -0.7 DNA cytosine methylase (NCBI) compare
b1778 yeaA -0.6 -2.2 methionine sulfoxide reductase B (NCBI) compare
b4232 fbp -0.6 -5.2 fructose-1,6-bisphosphatase (NCBI) compare
b1865 nudB -0.6 -1.1 dATP pyrophosphohydrolase (NCBI) compare
b0785 moaE -0.6 -2.8 molybdopterin synthase, large subunit (NCBI) compare
b2897 ygfY -0.6 -2.3 hypothetical protein (NCBI) compare
b4497 yeeL -0.6 -1.0 no description compare
b1291 sapD -0.6 -0.9 predicted antimicrobial peptide transporter subunit (NCBI) compare
b3389 aroB -0.6 -4.3 3-dehydroquinate synthase (NCBI) compare
b0015 dnaJ -0.6 -4.5 chaperone Hsp40, co-chaperone with DnaK (NCBI) compare
b0161 degP -0.6 -3.8 serine endoprotease (protease Do), membrane-associated (NCBI) compare
b2448 yffQ -0.6 -2.5 CPZ-55 prophage; predicted protein (RefSeq) compare
b3621 rfaC -0.6 -3.2 ADP-heptose:LPS heptosyl transferase I (NCBI) compare
b0729 sucD -0.6 -1.7 succinyl-CoA synthetase subunit alpha (NCBI) compare
b1502 ydeQ -0.6 -1.5 predicted fimbrial-like adhesin protein (NCBI) compare
b3935 priA -0.6 -1.9 primosome assembly protein PriA (NCBI) compare
b3786 rffE -0.6 -4.9 UDP-N-acetyl glucosamine-2-epimerase (NCBI) compare
b2055 wcaE -0.6 -0.3 predicted glycosyl transferase (NCBI) compare
b4402 yjjY -0.6 -1.0 hypothetical protein (NCBI) compare
b1171 b1171 -0.6 -1.8 orf, hypothetical protein (VIMSS) compare
b0676 nagC -0.6 -3.6 DNA-binding transcriptional dual regulator, repressor of N-acetylglucosamine (NCBI) compare
b0688 pgm -0.6 -2.0 phosphoglucomutase (NCBI) compare
b4493 gapC -0.6 -1.5 no description compare
b0889 lrp -0.6 -2.0 DNA-binding transcriptional dual regulator, leucine-binding (NCBI) compare
b1236 galU -0.6 -2.4 glucose-1-phosphate uridylyltransferase (NCBI) compare
b1138 ymfE -0.6 -1.0 e14 prophage; predicted inner membrane protein (NCBI) compare
b0881 clpS -0.6 -1.1 ATP-dependent Clp protease adaptor protein ClpS (NCBI) compare
b3181 greA -0.6 -2.9 transcription elongation factor: cleaves 3' nucleotide of paused mRNA (VIMSS) compare
b0437 clpP -0.6 -3.3 ATP-dependent Clp protease proteolytic subunit (NCBI) compare
b2432 yfeY -0.6 -1.4 hypothetical protein (NCBI) compare
b1332 ynaJ -0.5 -0.4 predicted inner membrane protein (NCBI) compare
b3867 hemN -0.5 -4.4 O2-independent coproporphyrinogen III oxidase (VIMSS) compare
b1630 rsxD -0.5 -3.2 electron transport complex protein RnfD (NCBI) compare
b1334 fnr -0.5 -1.9 DNA-binding transcriptional dual regulator, global regulator of anaerobic growth (NCBI) compare
b1074 flgC -0.5 -1.6 flagellar basal-body rod protein C (NCBI) compare
b3388 damX -0.5 -4.5 hypothetical protein (NCBI) compare
b2784 relA -0.5 -4.3 (p)ppGpp synthetase I/GTP pyrophosphokinase (NCBI) compare
b4416 rybA -0.5 -1.0 unknown RNA (NCBI) compare
b2455 eutE -0.5 -2.9 predicted aldehyde dehydrogenase, ethanolamine utilization protein (NCBI) compare
b0310 ykgH -0.5 -0.9 predicted inner membrane protein (NCBI) compare
b0406 tgt -0.5 -2.9 queuine tRNA-ribosyltransferase (NCBI) compare
b3794 rffM -0.5 -3.7 putative UDP-N-acetyl-D-mannosaminuronic acid transferase (NCBI) compare
b1951 rcsA -0.5 -0.9 DNA-binding transcriptional activator, co-regulator with RcsB (NCBI) compare
b0418 pgpA -0.5 -2.9 phosphatidylglycerophosphatase A (NCBI) compare
b0439 lon -0.5 -2.8 DNA-binding ATP-dependent protease La (NCBI) compare
b2052 fcl -0.5 -3.5 bifunctional GDP-fucose synthetase: GDP-4-dehydro-6-deoxy-D-mannose epimerase/ GDP-4-dehydro-6-L-deoxygalactose reductase (NCBI) compare
b3890 yiiF -0.5 -2.3 orf, hypothetical protein (VIMSS) compare
b3849 trkH -0.5 -4.1 potassium transporter (NCBI) compare
b4413 sokC -0.5 -1.1 regulatory antisense RNA (NCBI) compare
b2433 b2433 -0.5 -1.5 orf, hypothetical protein (VIMSS) compare
b4426 isrA -0.5 -1.3 unknown RNA (NCBI) compare
b3787 rffD -0.5 -4.0 UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase (NCBI) compare
b1084 rne -0.5 -2.4 fused ribonucleaseE: endoribonuclease/RNA-binding protein/RNA degradosome binding protein (NCBI) compare
b2414 cysK -0.5 -3.3 cysteine synthase A, O-acetylserine sulfhydrolase A subunit (NCBI) compare
b1279 yciS -0.5 -0.8 conserved inner membrane protein (NCBI) compare
b4179 vacB -0.5 -2.7 putative enzyme (VIMSS) compare
b0677 nagA -0.5 -2.9 N-acetylglucosamine-6-phosphate deacetylase (NCBI) compare
b1527 yneK -0.5 -1.3 hypothetical protein (NCBI) compare
b0504 ybbS -0.5 -2.3 DNA-binding transcriptional activator of the allD operon (NCBI) compare
b2516 yfgA -0.5 -3.2 hypothetical protein (NCBI) compare
b2951 yggS -0.5 -2.1 predicted enzyme (NCBI) compare
b1161 ycgX -0.5 -0.5 hypothetical protein (NCBI) compare
b3652 recG -0.5 -3.4 ATP-dependent DNA helicase (NCBI) compare
b4702 mgtL -0.5 -1.0 regulatory leader peptide for mgtA (NCBI) compare
b3601 mtlR -0.5 -3.4 DNA-binding repressor (NCBI) compare
b0004 thrC -0.5 -3.3 threonine synthase (NCBI) compare
b1762 b1762 -0.5 -1.5 orf, hypothetical protein (VIMSS) compare
b1363 trkG -0.5 -0.5 Rac prophage; potassium transporter subunit (NCBI) compare
b1130 phoP -0.5 -0.8 DNA-binding response regulator in two-component regulatory system with PhoQ (NCBI) compare
b3341 rpsG -0.5 -0.6 30S ribosomal protein S7 (NCBI) compare
b0965 b0965 -0.5 -1.7 orf, hypothetical protein (VIMSS) compare
b0438 clpX -0.5 -2.9 ATP-dependent protease ATP-binding subunit (NCBI) compare


Specific Phenotypes

For 1 genes in this experiment