Experiment set15IT069 for Pseudomonas putida KT2440

Compare to:

3-Methyl-2-Oxobutanoic Acid carbon source

200 most detrimental genes:

  gene name fitness t score description  
PP_4994 +1.8 9.0 conserved protein of unknown function compare
PP_1623 +1.8 12.2 RNA polymerase, sigma S (sigma 38) factor compare
PP_1650 +1.7 16.9 Sensor protein GacS compare
PP_4099 +1.7 16.6 two-componenent system BarA/UvrY - regulatory subunit compare
PP_2031 +1.5 2.5 conserved protein of unknown function compare
PP_0547 +1.4 5.6 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase compare
PP_3198 +1.4 1.7 Ferredoxin, 2Fe-2S compare
PP_1224 +1.2 5.6 periplasmic subunit of the TolQRA transport system compare
PP_1898 +1.2 2.6 MotA/TolQ/ExbB proton channel family protein compare
PP_4296 +1.1 1.3 conserved exported protein of unknown function compare
PP_1778 +1.1 6.2 Lipopolysaccharide ABC export system, permease protein compare
PP_2144 +1.1 3.5 Transcriptional regulator, TetR family compare
PP_0274 +1.0 2.3 putative transcriptional regulator containing HTH domain compare
PP_0022 +1.0 1.4 hypothetical protein compare
PP_1164 +1.0 2.2 Transcriptional regulator, LysR family compare
PP_3532 +1.0 2.0 Transcriptional regulator, AsnC family compare
PP_4171 +1.0 7.9 conserved exported protein of unknown function compare
PP_0276 +0.9 1.5 Transcriptional regulator, Cro/CI family compare
PP_1779 +0.9 4.7 Lipopolysaccharide ABC export system, ATP-binding protein compare
PP_4981 +0.9 3.3 polyisoprene-binding protein, acidic stress response factor compare
PP_4227 +0.9 1.5 conserved protein of unknown function compare
PP_4874 +0.9 0.9 50S ribosomal protein L9 compare
PP_4196 +0.9 3.0 conserved exported protein of unknown function compare
PP_3241 +0.9 1.5 conserved exported protein of unknown function compare
PP_2499 +0.9 1.2 conserved protein of unknown function compare
PP_2580 +0.9 2.5 conserved protein of unknown function compare
PP_5008 +0.9 1.7 Poly granule-associated protein compare
PP_5445 +0.9 3.4 conserved protein of unknown function compare
PP_2027 +0.9 2.7 conserved exported protein of unknown function compare
PP_1004 +0.9 2.5 conserved protein of unknown function compare
PP_4265 +0.9 2.8 DNA-binding transcriptional dual regulator compare
PP_3411 +0.9 1.4 conserved protein of unknown function compare
PP_5106 +0.9 1.9 conserved inner membrane protein compare
PP_t10 +0.9 1.2 tRNA-Pro compare
PP_5546 +0.8 2.3 conserved protein of unknown function compare
PP_1113 +0.8 5.5 Pyridoxal-phosphate dependent enzyme family protein compare
PP_4271 +0.8 0.7 conserved protein of unknown function compare
PP_4133 +0.8 1.8 Transcriptional regulator-related protein compare
PP_1198 +0.8 2.0 transcriptional regulator, Cro/CI family (higA antitoxin like) compare
PP_3880 +0.8 1.6 conserved exported protein of unknown function compare
PP_4835 +0.8 0.9 conserved exported protein of unknown function compare
PP_2137 +0.8 2.0 beta-ketoadipyl CoA thiolase, beta component compare
PP_4354 +0.8 3.8 flagellar export apparatus subunit compare
PP_4847 +0.8 1.2 chaperone modulatory of CbpA co-chaperone protein compare
PP_3254 +0.7 2.8 putative Nucleosidase compare
PP_2668 +0.7 2.0 ABC efflux transporter, ATP-binding protein compare
PP_5066 +0.7 3.0 K(+)/H(+) antiporter NhaP2 compare
PP_4561 +0.7 1.0 stress response protein compare
PP_5000 +0.7 1.2 peptidase component of the ATP-dependent HslVU protease compare
PP_5712 +0.7 2.9 conserved protein of unknown function compare
PP_0138 +0.7 4.3 conserved membrane protein of unknown function compare
PP_3726 +0.7 1.0 Enoyl-CoA hydratase/isomerase family protein compare
PP_1410 +0.7 1.1 conserved protein of unknown function compare
PP_4697 +0.7 1.9 poly(A) polymerase compare
PP_4102 +0.7 1.5 conserved protein of unknown function compare
PP_4707 +0.7 1.1 OsmY-related protein compare
PP_1344 +0.7 0.9 conserved protein of unknown function compare
PP_5241 +0.6 1.2 DNA-binding response regulator, LuxR family compare
PP_3234 +0.6 1.7 Heat shock protein, HSP20 family compare
PP_3810 +0.6 2.0 conserved protein of unknown function compare
PP_1776 +0.6 5.1 Mannose-6-phosphate isomerase/mannose-1-phosphate guanylyltransferase compare
PP_4356 +0.6 2.2 Flagellar protein FliO compare
PP_0711 +0.6 2.0 putative hydrolase compare
PP_2109 +0.6 2.4 conserved protein of unknown function compare
PP_4660 +0.6 2.0 Transcriptional regulator, LysR family compare
PP_4273 +0.6 1.2 Transcriptional regulator, MerR family compare
PP_3899 +0.6 1.2 conserved protein of unknown function, hicB family compare
PP_5201 +0.6 0.9 conserved protein of unknown function, UPF0149 family compare
PP_2322 +0.6 4.6 Major outer membrane lipoprotein compare
PP_1649 +0.6 2.3 D-lactate dehydrogenase compare
PP_4528 +0.6 1.7 conserved protein of unknown function compare
PP_4034 +0.6 2.6 N-carbamoyl-beta-alanine amidohydrolase/allantoine amidohydrolase 2 compare
PP_3923 +0.6 2.3 Phosphoglycerate mutase compare
PP_0674 +0.6 4.6 ADP/ATP ratio sensor and inhibitor of translation compare
PP_2772 +0.6 2.6 putative Monooxygenase compare
PP_5658 +0.6 1.3 protein of unknown function compare
PP_1062 +0.6 2.0 MutT/nudix family protein compare
PP_1804 +0.6 4.4 Glycosyl transferase WbpL compare
PP_0502 +0.6 1.9 conserved protein of unknown function compare
PP_3792 +0.6 1.5 conserved protein of unknown function compare
PP_2813 +0.6 1.5 BNR domain protein compare
PP_2320 +0.6 4.8 conserved exported protein of unknown function compare
PP_2725 +0.6 1.1 Protease PfpI compare
PP_2459 +0.6 1.4 ribose pyranase compare
PP_0398 +0.6 1.2 Thiosulfate sulfurtransferase GlpE compare
PP_4050 +0.6 4.5 glycogen synthase compare
PP_3341 +0.6 2.2 nickel-responsive regulator compare
PP_0086 +0.6 0.9 conserved protein of unknown function compare
PP_2147 +0.6 1.2 conserved exported protein of unknown function compare
PP_5499 +0.6 1.9 conserved protein of unknown function compare
PP_5425 +0.6 2.6 conserved protein of unknown function compare
PP_0206 +0.6 1.7 Ferredoxin, 4Fe-4S compare
PP_1528 +0.6 0.8 conserved protein of unknown function compare
PP_5143 +0.6 1.0 conserved membrane protein of unknown function compare
PP_2581 +0.6 0.9 conserved protein of unknown function compare
PP_5597 +0.6 1.1 conserved protein of unknown function compare
PP_3888 +0.6 2.3 conserved protein of unknown function compare
PP_5191 +0.6 2.2 conserved exported protein of unknown function compare
PP_2009 +0.5 2.5 putative 1-aminocyclopropane-1-carboxylate deaminase compare
PP_2916 +0.5 1.8 riboflavin synthase compare
PP_0801 +0.5 0.8 conserved exported protein of unknown function compare
PP_3773 +0.5 1.7 conserved protein of unknown function compare
PP_1381 +0.5 0.6 4-carboxymuconolactone decarboxylase compare
PP_4373 +0.5 3.8 Transcriptional regulator FleQ compare
PP_3000 +0.5 2.6 MaoC domain protein compare
PP_0191 +0.5 1.7 Transcriptional regulatory protein AlgQ compare
PP_5428 +0.5 2.6 conserved exported protein of unknown function compare
PP_2718 +0.5 0.5 arsenic resistance transcriptional regulator compare
PP_5475 +0.5 0.5 conserved protein of unknown function compare
PP_5483 +0.5 0.7 conserved protein of unknown function compare
PP_2160 +0.5 1.7 NADPH-dependent 7-cyano-7-deazaguanine reductase compare
PP_4367 +0.5 1.7 Flagellar assembly protein FliH compare
PP_3509 +0.5 1.2 Glyoxalase family protein compare
PP_0250 +0.5 0.9 heat shock protein Hsp15 involved in ribosome recycling compare
PP_4687 +0.5 2.4 Hemin import ATP-binding protein HmuV compare
PP_0492 +0.5 2.6 formate dehydrogenase formation protein compare
PP_2357 +0.5 1.7 putative Type 1 pili protein CsuB compare
PP_4217 +0.5 4.5 outer membrane ferripyoverdine receptor FpvA, TonB-dependent compare
PP_4262 +0.5 1.4 Cytochrome oxidase maturation protein, cbb3-type compare
PP_2908 +0.5 1.0 DNA-binding transcriptional repressor compare
PP_2422 +0.5 1.7 conserved protein of unknown function compare
PP_2196 +0.5 1.4 agmatinase compare
PP_2835 +0.5 1.4 putative oxidoreductase compare
PP_2764 +0.5 1.2 FMN reductase (NADPH) compare
PP_3637 +0.5 0.8 putative Sulfonate ABC transporter, ATP-binding protein compare
PP_3797 +0.5 2.2 conserved membrane protein of unknown function compare
PP_0640 +0.5 0.9 conserved protein of unknown function compare
PP_1801 +0.5 3.3 Glycosyl transferase WbpY compare
PP_1170 +0.5 2.1 D-glucaro-1,5-lactonase UxuL (from data) compare
PP_0540 +0.5 1.6 conserved inner membrane protein compare
PP_2319 +0.5 2.4 conserved protein of unknown function compare
PP_2387 +0.5 1.3 conserved protein of unknown function compare
PP_4368 +0.5 2.5 flagellar motor switch protein compare
PP_1454 +0.5 1.5 conserved protein of unknown function compare
PP_4870 +0.5 1.4 Azurin compare
PP_4785 +0.5 2.8 conserved exported protein of unknown function compare
PP_3884 +0.5 1.7 Phage holin, lambda family compare
PP_3892 +0.5 0.9 conserved protein of unknown function compare
PP_4490 +0.5 3.0 phenylalanine-4-hydroxylase compare
PP_1371 +0.5 2.1 Methyl-accepting chemotaxis protein PctA compare
PP_3730 +0.5 0.6 Transcriptional regulatory protein AruR compare
PP_2203 +0.5 1.1 conserved protein of unknown function compare
PP_1299 +0.5 2.6 putative amino acid ABC transporter - membrane subunit compare
PP_2745 +0.5 1.4 Universal stress protein family compare
PP_5194 +0.5 2.6 aminomethyltransferase compare
PP_1068 +0.5 1.3 glutamate / aspartate ABC transporter - ATP binding subunit compare
PP_2049 +0.5 2.4 Alcohol dehydrogenase, iron-containing compare
PP_0679 +0.5 2.1 conserved exported protein of unknown function compare
PP_0653 +0.5 0.9 conserved protein of unknown function compare
PP_4054 +0.5 0.9 conserved protein of unknown function compare
PP_0960 +0.5 1.7 phospholipid ABC transporter binding protein compare
PP_4669 +0.5 0.8 OmpA family protein compare
PP_1805 +0.5 3.8 Polysaccharide biosynthesis protein compare
PP_4706 +0.5 1.7 conserved protein of unknown function compare
PP_1733 +0.5 1.2 membrane ATPase of the MinC-MinD-MinE system compare
PP_3083 +0.5 2.1 putative Membrane protein compare
PP_4159 +0.5 1.3 Potassium-transporting ATPase C chain compare
PP_4214 +0.4 1.3 pyoverdine biosynthesis related protein compare
PP_2323 +0.4 3.4 conserved protein of unknown function compare
PP_1478 +0.4 2.2 putative Xenobiotic reductase compare
PP_0262 +0.4 1.5 conserved protein of unknown function compare
PP_2388 +0.4 1.6 Transporter, LysE family compare
PP_3589 +0.4 2.0 serine:H+ symport permease, threonine-insensitive compare
PP_0984 +0.4 2.3 conserved membrane protein of unknown function compare
PP_1269 +0.4 0.8 Universal stress protein family compare
PP_3744 +0.4 2.0 transcriptional dual regulator GlcC-Glycolate compare
PP_3173 +0.4 2.0 N-ethylmaleimide reductase, FMN-linked compare
PP_2067 +0.4 2.1 putative EmrB/QacA family drug resistance transporter compare
PP_4385 +0.4 1.8 flagellar basal-body rod protein FlgG compare
PP_1780 +0.4 3.9 putative mannosyltransferase compare
PP_1777 +0.4 3.1 phosphomannomutase compare
PP_1803 +0.4 3.6 UDP-sugar epimerase compare
PP_5184 +0.4 1.9 glutamylpolyamine synthetase compare
PP_0833 +0.4 0.7 queuine tRNA-ribosyltransferase compare
PP_1012 +0.4 1.7 DNA-binding response regulator compare
PP_3233 +0.4 1.3 transcriptional regulator with 4Fe-4S cluster, Crp/Fnr family compare
PP_4804 +0.4 1.6 RlpA-like lipoprotein compare
PP_4308 +0.4 1.3 Transcriptional regulator, AsnC family compare
PP_2951 +0.4 2.0 Transcriptional regulator, TetR family compare
PP_3365 +0.4 0.7 Acetolactate synthase compare
PP_0713 +0.4 2.6 Kef-type potassium/proton antiporter, CPA2 family compare
PP_0361 +0.4 1.5 putative Competence protein ComF compare
PP_2036 +0.4 2.0 putative 4-hydroxy-tetrahydrodipicolinate synthase compare
PP_2389 +0.4 1.8 conserved protein of unknown function compare
PP_1503 +0.4 0.8 conserved protein of unknown function compare
PP_4208 +0.4 2.2 RNA polymerase sigma-70 factor, ECF subfamily compare
PP_t13 +0.4 0.7 tRNA-Lys compare
PP_1135 +0.4 2.2 conserved exported protein of unknown function compare
PP_0961 +0.4 2.0 toluene tolerance protein compare
PP_1808 +0.4 1.1 glucose-6-phosphate isomerase compare
PP_3380 +0.4 1.5 2-ketogluconate utilization repressor compare
PP_0332 +0.4 1.4 putative Acyltransferase compare
PP_1799 +0.4 3.3 GDP-mannose 4,6-dehydratase compare
PP_2798 +0.4 1.4 putative Oxidoreductase compare
PP_4751 +0.4 2.3 Amino acid ABC transporter, ATP-binding protein compare
PP_1476 +0.4 1.8 conserved protein of unknown function compare
PP_1310 +0.4 1.2 conserved hypothetical protein compare
PP_3578 +0.4 2.4 phosphoglucomutase compare
PP_3821 +0.4 2.3 UTP-glucose-1-phosphate uridylyltransferase compare
PP_1723 +0.4 2.3 putative 2-aminoethylphosphonate transport system permease compare


Specific Phenotypes

For 14 genes in this experiment

For carbon source 3-Methyl-2-Oxobutanoic Acid in Pseudomonas putida KT2440

For carbon source 3-Methyl-2-Oxobutanoic Acid across organisms