Experiment set15IT060 for Pseudomonas putida KT2440

Compare to:

Valeric acid carbon source

200 most detrimental genes:

  gene name fitness t score description  
PP_3539 +3.8 16.0 putative Transcriptional regulator compare
PP_1650 +3.1 30.0 Sensor protein GacS compare
PP_4099 +3.0 27.3 two-componenent system BarA/UvrY - regulatory subunit compare
PP_3551 +2.9 8.7 DNA-binding response regulator, LuxR family compare
PP_1968 +2.5 12.6 TetR family transcriptional regulator compare
PP_1623 +2.5 16.9 RNA polymerase, sigma S (sigma 38) factor compare
PP_2215 +2.1 12.1 acetyl-CoA acetyltransferase compare
PP_2214 +1.6 7.6 3-hydroxyacyl-CoA dehydrogenase type-2 compare
PP_4171 +1.2 8.7 conserved exported protein of unknown function compare
PP_2889 +1.2 4.1 putative Transmembrane regulator PrtR compare
PP_0177 +1.1 6.5 conserved protein of unknown function compare
PP_0176 +1.1 8.4 putative efflux transporter compare
PP_3328 +1.1 2.8 putative Ring-cleaving dioxygenase compare
PP_1293 +1.1 0.9 molybdopterin synthase small subunit compare
PP_0179 +1.1 8.6 putative efflux transporter compare
PP_0893 +1.1 2.3 ThiJ/PfpI family protein compare
PP_4710 +1.1 7.7 tRNA pseudouridine 55 synthase compare
PP_2210 +1.1 2.9 LysR family transcriptional regulator compare
PP_3651 +1.0 8.3 Sensor histidine kinase/response regulator compare
PP_1164 +1.0 2.9 Transcriptional regulator, LysR family compare
PP_5232 +1.0 3.6 conserved protein of unknown function compare
PP_3552 +1.0 4.0 Sensory box histidine kinase compare
PP_0508 +1.0 4.4 conserved exported protein of unknown function compare
PP_4828 +1.0 2.1 Precorrin-8X methylmutase compare
PP_1655 +1.0 4.5 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD compare
PP_3637 +1.0 2.0 putative Sulfonate ABC transporter, ATP-binding protein compare
PP_1004 +0.9 2.0 conserved protein of unknown function compare
PP_2568 +0.9 1.6 Ring-cleaving dioxygenase compare
PP_2437 +0.9 5.9 putative Acyl-CoA dehydrogenase compare
PP_1656 +0.9 4.4 ATP:GTP 3'-pyrophosphotransferase compare
PP_4227 +0.9 1.2 conserved protein of unknown function compare
PP_0178 +0.9 6.7 putative efflux pump compare
PP_0948 +0.9 3.3 Phosphocarrier protein HPr compare
PP_1553 +0.9 1.7 conserved protein of unknown function compare
PP_2387 +0.9 3.0 conserved protein of unknown function compare
PP_5582 +0.8 1.7 conserved protein of unknown function compare
PP_4804 +0.8 3.0 RlpA-like lipoprotein compare
PP_2747 +0.8 2.3 conserved protein of unknown function compare
PP_1736 +0.8 3.8 conserved protein of unknown function compare
PP_2103 +0.8 2.1 conserved protein of unknown function compare
PP_2970 +0.8 2.5 conserved exported protein of unknown function compare
PP_4159 +0.8 3.5 Potassium-transporting ATPase C chain compare
PP_3532 +0.8 1.7 Transcriptional regulator, AsnC family compare
PP_4707 +0.8 2.4 OsmY-related protein compare
PP_2899 +0.8 1.5 conserved exported protein of unknown function compare
PP_4065 +0.7 5.2 methylcrotonyl-CoA carboxylase biotin-containing subunit beta compare
PP_5610 +0.7 2.4 protein of unknown function compare
PP_4054 +0.7 1.5 conserved protein of unknown function compare
PP_0674 +0.7 5.3 ADP/ATP ratio sensor and inhibitor of translation compare
PP_3874 +0.7 1.8 conserved protein of unknown function compare
PP_1344 +0.7 0.9 conserved protein of unknown function compare
PP_3052 +0.7 1.2 conserved protein of unknown function compare
PP_4066 +0.7 2.2 methylglutaconyl-CoA hydratase compare
PP_5145 +0.7 6.6 phosphoenolpyruvate-dependent regulator (with NPR and NTR proteins) compare
PP_3614 +0.7 3.0 conserved membrane protein of unknown function compare
PP_0765 +0.7 5.7 putative adhesin (DUF1302) (from data) compare
PP_3380 +0.7 2.7 2-ketogluconate utilization repressor compare
PP_5508 +0.7 1.1 conserved protein of unknown function compare
PP_4207 +0.7 1.1 conserved protein of unknown function compare
PP_2389 +0.7 2.7 conserved protein of unknown function compare
PP_3908 +0.6 2.7 conserved protein of unknown function compare
PP_5648 +0.6 2.6 conserved exported protein of unknown function compare
PP_4370 +0.6 3.1 Flagellar hook-basal body complex protein FliE compare
PP_3580 +0.6 1.2 conserved protein of unknown function compare
PP_0979 +0.6 2.2 DNA polymerase III subunit chi compare
PP_0533 +0.6 3.1 histidine kinase compare
PP_4785 +0.6 3.7 conserved exported protein of unknown function compare
PP_5298 +0.6 2.0 putative glutamine amidotransferase compare
PP_4006 +0.6 4.6 Putative arginyl-tRNA--protein transferase compare
PP_3823 +0.6 2.3 Cytochrome c-type protein compare
PP_0122 +0.6 2.1 conserved exported protein of unknown function compare
PP_3411 +0.6 0.6 conserved protein of unknown function compare
PP_4739 +0.6 3.0 conserved protein of unknown function compare
PP_4519 +0.6 5.3 Agglutination protein compare
PP_0685 +0.6 1.1 conserved protein of unknown function compare
PP_2835 +0.6 1.8 putative oxidoreductase compare
PP_0340 +0.6 4.7 Glutamate-ammonia-ligase adenylyltransferase compare
PP_3546 +0.6 4.7 Sensory box histidine kinase/response regulator compare
PP_2922 +0.6 2.4 Urea amidolyase-related protein compare
PP_2718 +0.6 1.3 arsenic resistance transcriptional regulator compare
PP_1575 +0.6 1.4 conserved protein of unknown function compare
PP_4373 +0.6 4.5 Transcriptional regulator FleQ compare
PP_2189 +0.6 2.6 conserved protein of unknown function compare
PP_0891 +0.6 2.7 conserved exported protein of unknown function compare
PP_2118 +0.6 1.5 conserved protein of unknown function compare
PP_0766 +0.6 4.6 adhesin-associated sorting protein (DUF1329) (from data) compare
PP_2018 +0.6 2.0 adhesin-associated BNR repeat protein (from data) compare
PP_2700 +0.6 1.1 AhpC/TSA family protein compare
PP_2672 +0.6 2.7 Transcriptional activator protein ExaE compare
PP_4406 +0.6 1.5 conserved protein of unknown function compare
PP_0138 +0.6 3.1 conserved membrane protein of unknown function compare
PP_0547 +0.6 2.0 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase compare
PP_4050 +0.6 4.6 glycogen synthase compare
PP_3831 +0.6 3.1 conserved protein of unknown function compare
PP_0168 +0.5 5.1 putative surface adhesion protein compare
PP_5480 +0.5 2.9 conserved exported protein of unknown function compare
PP_4803 +0.5 4.1 D-alanyl-D-alanine carboxypeptidase compare
PP_3971 +0.5 0.8 conserved protein of unknown function compare
PP_5157 +0.5 1.5 conserved exported protein of unknown function compare
PP_2365 +0.5 2.6 Transcriptional regulator, AraC family compare
PP_4067 +0.5 4.1 methylcrotonyl-CoA carboxylase biotin-containing subunit alpha compare
PP_1729 +0.5 1.5 conserved protein of unknown function compare
PP_4108 +0.5 2.1 2-aminoadipate transaminase (EC 2.6.1.39) (from data) compare
PP_4830 +0.5 2.8 precorrin-6Y C(5,15)-methyltransferase compare
PP_5469 +0.5 2.3 putative SAM-dependent methyltransferase compare
PP_0880 +0.5 1.1 dipeptide ABC transporter - putative membrane subunit compare
PP_0803 +0.5 3.0 Protein secretion ABC efflux system, membrane fusion protein compare
PP_2073 +0.5 2.4 Acetyltransferase, GNAT family compare
PP_2814 +0.5 1.7 conserved protein of unknown function compare
PP_2742 +0.5 2.7 conserved protein of unknown function compare
PP_1774 +0.5 0.8 conserved exported protein of unknown function compare
PP_3743 +0.5 3.3 conserved exported protein of unknown function compare
PP_4513 +0.5 1.8 conserved protein of unknown function compare
PP_5328 +0.5 1.9 putative phosphate transport system permease protein compare
PP_2916 +0.5 1.3 riboflavin synthase compare
PP_5644 +0.5 2.0 conserved membrane protein of unknown function compare
PP_2422 +0.5 2.5 conserved protein of unknown function compare
PP_1512 +0.5 1.6 conserved protein of unknown function compare
PP_3061 +0.5 1.6 conserved protein of unknown function compare
PP_1867 +0.5 2.6 conserved protein of unknown function compare
PP_1245 +0.5 1.9 conserved exported protein of unknown function compare
PP_5381 +0.5 1.9 hypothetical protein compare
PP_0512 +0.5 1.1 hypothetical protein compare
PP_4499 +0.5 2.2 putative maturation enzyme compare
PP_1755 +0.5 2.6 fumarate hydratase (class 2) compare
PP_2350 +0.5 2.8 LysR family transcriptional regulator compare
PP_1702 +0.5 1.3 Recombination-associated protein RdgC compare
PP_1352 +0.5 1.6 UPF0234 protein PP_1352 compare
PP_3247 +0.5 1.5 Transporter, bile acid/Na+ symporter family compare
PP_2254 +0.5 2.9 Transcriptional regulator, GntR family compare
PP_5163 +0.5 2.8 maltose acetyltransferase compare
PP_3930 +0.5 1.1 conserved exported protein of unknown function compare
PP_3241 +0.5 0.8 conserved exported protein of unknown function compare
PP_4929 +0.5 1.7 Transcriptional regulator, LysR family compare
PP_4961 +0.5 0.7 putative Lipoprotein compare
PP_2772 +0.5 2.3 putative Monooxygenase compare
PP_4271 +0.5 0.5 conserved protein of unknown function compare
PP_1113 +0.5 3.0 Pyridoxal-phosphate dependent enzyme family protein compare
PP_0191 +0.5 1.8 Transcriptional regulatory protein AlgQ compare
PP_1855 +0.5 2.2 conserved exported protein of unknown function compare
PP_3434 +0.5 1.8 conserved protein of unknown function compare
PP_0206 +0.5 1.5 Ferredoxin, 4Fe-4S compare
PP_2712 +0.5 1.5 conserved exported protein of unknown function compare
PP_1415 +0.5 1.2 putative membrane associated enzyme subunit compare
PP_2675 +0.5 1.7 Cytochrome c-type protein compare
PP_1674 +0.5 1.9 5,6-dimethylbenzimidazole synthase compare
PP_2061 +0.5 1.2 conserved protein of unknown function compare
PP_5483 +0.5 0.9 conserved protein of unknown function compare
PP_3392 +0.5 0.4 conserved protein of unknown function compare
PP_2740 +0.5 1.3 Transcriptional regulator, MerR family compare
PP_4517 +0.5 1.4 conserved protein of unknown function compare
PP_5053 +0.5 2.0 Protein-export protein SecB compare
PP_0899 +0.5 3.3 putative Ferredoxin reductase compare
PP_5457 +0.5 2.1 conserved protein of unknown function compare
PP_2705 +0.5 1.3 conserved protein of unknown function compare
PP_1066 +0.5 2.2 C4-dicarboxylate transport transcriptional regulatory protein compare
PP_0804 +0.5 3.2 Protein secretion ABC efflux system, permease and ATP-binding protein compare
PP_0941 +0.5 1.2 putative ribosome associated protein compare
PP_5254 +0.5 2.6 conserved protein of unknown function compare
PP_3522 +0.5 1.5 conserved protein of unknown function compare
PP_3209 +0.5 2.7 Isoxanthopterin deaminase compare
PP_2390 +0.5 2.6 Transcriptional regulator, LysR family compare
PP_0806 +0.5 4.2 putative Surface adhesion protein compare
PP_2172 +0.5 2.1 conserved exported protein of unknown function compare
PP_2459 +0.5 1.1 ribose pyranase compare
PP_5504 +0.5 2.3 conserved protein of unknown function compare
PP_4835 +0.5 1.1 conserved exported protein of unknown function compare
PP_1534 +0.5 1.9 conserved protein of unknown function compare
PP_4871 +0.5 1.6 putative lysine decarboxylase family protein compare
PP_4833 +0.5 2.0 SURF1 domain protein compare
PP_0610 +0.5 1.3 conserved exported protein of unknown function compare
PP_5225 +0.4 1.0 frataxin compare
PP_3040 +0.4 1.1 Pyocin R2_PP, holin compare
PP_3919 +0.4 1.2 conserved protein of unknown function compare
PP_4059 +0.4 3.7 fused trehalose synthase B/maltokinase compare
PP_0232 +0.4 0.6 ATP-binding taurine transporter subunit compare
PP_3135 +0.4 2.4 putative Glycosyl transferase compare
PP_2725 +0.4 1.0 Protease PfpI compare
PP_2907 +0.4 1.5 DNA-binding response regulator compare
PP_2677 +0.4 2.1 conserved exported protein of unknown function compare
PP_1084 +0.4 2.0 putative peroxiredoxin compare
PP_2894 +0.4 2.3 conserved protein of unknown function compare
PP_5628 +0.4 0.8 conserved protein of unknown function compare
PP_0395 +0.4 3.3 putative type IV piliation protein compare
PP_1676 +0.4 2.2 subunit of adenosylcobinamide-phosphate synthase beta component compare
PP_5096 +0.4 1.8 putative factor involved in shape determination compare
PP_0262 +0.4 2.1 conserved protein of unknown function compare
PP_4687 +0.4 1.7 Hemin import ATP-binding protein HmuV compare
PP_3097 +0.4 3.3 conserved protein of unknown function compare
PP_4102 +0.4 1.2 conserved protein of unknown function compare
PP_3805 +0.4 2.3 lipoprotein required for swarming compare
PP_2658 +0.4 1.9 phosphate ABC transporter compare
PP_5451 +0.4 1.8 protein of unknown function compare
PP_1042 +0.4 1.6 Type II secretion system protein K compare
PP_0886 +0.4 1.0 conserved exported protein of unknown function compare
PP_3145 +0.4 2.0 conserved protein of unknown function compare
PP_0532 +0.4 2.1 conserved exported protein of unknown function compare
PP_4329 +0.4 1.0 FlhB domain protein compare
PP_3254 +0.4 1.3 putative Nucleosidase compare
PP_2681 +0.4 0.8 coenzyme PQQ synthesis protein D compare


Specific Phenotypes

For 8 genes in this experiment

For carbon source Valeric acid in Pseudomonas putida KT2440

For carbon source Valeric acid across organisms