Experiment set15IT056 for Pseudomonas putida KT2440

Compare to:

4-Methyl-2-oxopentanoic acid carbon source

200 most detrimental genes:

  gene name fitness t score description  
PP_3286 +5.5 26.1 DNA-binding transcriptional repressor PaaX(phenylacetyl-CoA) compare
PP_1779 +1.8 8.8 Lipopolysaccharide ABC export system, ATP-binding protein compare
PP_1778 +1.7 7.4 Lipopolysaccharide ABC export system, permease protein compare
PP_1650 +1.6 16.1 Sensor protein GacS compare
PP_4099 +1.6 15.4 two-componenent system BarA/UvrY - regulatory subunit compare
PP_3551 +1.3 3.0 DNA-binding response regulator, LuxR family compare
PP_1410 +1.3 2.3 conserved protein of unknown function compare
PP_1898 +1.3 2.5 MotA/TolQ/ExbB proton channel family protein compare
PP_4196 +1.3 4.0 conserved exported protein of unknown function compare
PP_4008 +1.2 6.4 ATP-dependent serine protease compare
PP_3926 +1.2 2.8 short-chain dehydrogenase compare
PP_4994 +1.2 6.0 conserved protein of unknown function compare
PP_5000 +1.2 2.1 peptidase component of the ATP-dependent HslVU protease compare
PP_2335 +1.2 7.0 methylcitrate synthase compare
PP_5232 +1.2 2.2 conserved protein of unknown function compare
PP_4561 +1.2 1.7 stress response protein compare
PP_4227 +1.1 2.6 conserved protein of unknown function compare
PP_0276 +1.1 1.8 Transcriptional regulator, Cro/CI family compare
PP_4296 +1.1 1.5 conserved exported protein of unknown function compare
PP_2889 +1.0 3.4 putative Transmembrane regulator PrtR compare
PP_5572 +1.0 2.2 protein of unknown function compare
PP_2214 +1.0 3.1 3-hydroxyacyl-CoA dehydrogenase type-2 compare
PP_2773 +1.0 2.1 conserved protein of unknown function compare
PP_2430 +1.0 4.8 Transcriptional regulator, AraC family compare
PP_1122 +1.0 1.5 OmpA family protein compare
PP_4697 +1.0 2.9 poly(A) polymerase compare
PP_3035 +1.0 3.0 conserved protein of unknown function compare
PP_3365 +0.9 1.7 Acetolactate synthase compare
PP_4329 +0.9 2.5 FlhB domain protein compare
PP_1025 +0.9 6.7 2-isopropylmalate synthase compare
PP_5039 +0.9 1.5 conserved protein of unknown function compare
PP_4793 +0.9 2.3 conserved protein of unknown function compare
PP_0352 +0.9 2.2 RNA polymerase sigma-70 factor, ECF subfamily compare
PP_4667 +0.9 5.0 methylmalonate-semialdehyde dehydrogenase compare
PP_4268 +0.8 1.3 nucleoid-associated broad specificity regulator compare
PP_2070 +0.8 2.2 Transcriptional regulator, AraC family compare
PP_5073 +0.8 1.8 conserved exported protein of unknown function compare
PP_5569 +0.8 1.4 protein of unknown function of phage origin compare
PP_3504 +0.8 3.2 conserved protein of unknown function compare
PP_3946 +0.8 0.8 HTH-type transcriptional repressor NicR compare
PP_4172 +0.8 4.6 conserved exported protein of unknown function compare
PP_0283 +0.8 3.6 Arginine/ornithine transport ATP-binding protein AotP compare
PP_5448 +0.8 3.0 conserved protein of unknown function compare
PP_5008 +0.8 1.2 Poly granule-associated protein compare
PP_3318 +0.8 2.4 conserved protein of unknown function compare
PP_1562 +0.8 1.3 putative Phage terminase, small subunit compare
PP_5331 +0.8 3.5 Long-chain acyl-CoA thioester hydrolase compare
PP_4776 +0.8 5.6 AsnC family transcriptional regulator compare
PP_4785 +0.8 5.0 conserved exported protein of unknown function compare
PP_2387 +0.8 1.7 conserved protein of unknown function compare
PP_0025 +0.8 1.4 hypothetical protein compare
PP_0674 +0.8 5.8 ADP/ATP ratio sensor and inhibitor of translation compare
PP_2002 +0.7 2.3 putative enzyme compare
PP_2718 +0.7 1.4 arsenic resistance transcriptional regulator compare
PP_2976 +0.7 1.2 putative transposase compare
PP_2633 +0.7 1.7 conserved protein of unknown function compare
PP_0640 +0.7 1.8 conserved protein of unknown function compare
PP_0335 +0.7 2.1 Glutathione S-transferase family protein compare
PP_0540 +0.7 3.3 conserved inner membrane protein compare
PP_4262 +0.7 2.7 Cytochrome oxidase maturation protein, cbb3-type compare
PP_5054 +0.7 1.3 glutaredoxin 3 compare
PP_0832 +0.7 2.2 S-adenosylmethionine:tRNA ribosyltransferase-isomerase compare
PP_4980 +0.7 3.0 ATP-dependent RNA helicase compare
PP_2700 +0.7 1.6 AhpC/TSA family protein compare
PP_4171 +0.7 6.2 conserved exported protein of unknown function compare
PP_5440 +0.7 3.1 conserved protein of unknown function compare
PP_3891 +0.7 1.7 conserved protein of unknown function compare
PP_5253 +0.7 2.3 Arylesterase compare
PP_5075 +0.7 5.3 glutamate synthase (NADPH) beta subunit compare
PP_0945 +0.7 3.2 conserved protein of unknown function compare
PP_5546 +0.7 1.5 conserved protein of unknown function compare
PP_2322 +0.7 3.8 Major outer membrane lipoprotein compare
PP_4271 +0.7 0.6 conserved protein of unknown function compare
PP_5058 +0.7 2.9 Carboxy-terminal-processing protease compare
PP_2970 +0.7 1.8 conserved exported protein of unknown function compare
PP_2067 +0.7 2.1 putative EmrB/QacA family drug resistance transporter compare
PP_3519 +0.7 0.9 putative Lipoprotein compare
PP_5496 +0.7 3.1 conserved exported protein of unknown function compare
PP_0307 +0.7 1.6 conserved exported protein of unknown function compare
PP_1224 +0.6 2.4 periplasmic subunit of the TolQRA transport system compare
PP_5469 +0.6 1.8 putative SAM-dependent methyltransferase compare
PP_0725 +0.6 2.5 conserved hypothetical TPR repeat protein compare
PP_1776 +0.6 5.2 Mannose-6-phosphate isomerase/mannose-1-phosphate guanylyltransferase compare
PP_3409 +0.6 2.3 putative Cobalamin biosynthesis protein cobE compare
PP_1813 +0.6 2.0 ComEA-related protein compare
PP_0398 +0.6 3.0 Thiosulfate sulfurtransferase GlpE compare
PP_1513 +0.6 2.7 Ribosomal RNA small subunit methyltransferase J compare
PP_1096 +0.6 1.3 putative electron transport complex protein compare
PP_5229 +0.6 2.5 conserved protein of unknown function compare
PP_5256 +0.6 2.6 Cyclic nucleotide-binding protein compare
PP_2319 +0.6 2.4 conserved protein of unknown function compare
PP_4102 +0.6 2.5 conserved protein of unknown function compare
PP_2103 +0.6 1.7 conserved protein of unknown function compare
PP_1649 +0.6 1.9 D-lactate dehydrogenase compare
PP_4136 +0.6 1.1 Transcriptional regulator, LuxR family compare
PP_5106 +0.6 1.6 conserved inner membrane protein compare
PP_1770 +0.6 2.3 3-phosphoshikimate 1-carboxyvinyltransferase compare
PP_5648 +0.6 2.6 conserved exported protein of unknown function compare
PP_0566 +0.6 1.0 translation-related factor compare
PP_3770 +0.6 1.6 conserved protein of unknown function compare
PP_0262 +0.6 1.9 conserved protein of unknown function compare
PP_1142 +0.6 1.0 conserved protein of unknown function compare
PP_1293 +0.6 0.5 molybdopterin synthase small subunit compare
PP_4820 +0.6 2.7 tRNA-dihydrouridine synthase B compare
PP_4159 +0.6 1.3 Potassium-transporting ATPase C chain compare
PP_3434 +0.6 0.8 conserved protein of unknown function compare
PP_2389 +0.6 2.5 conserved protein of unknown function compare
PP_3840 +0.6 0.9 conserved protein of unknown function compare
PP_0152 +0.6 1.1 conserved exported protein of unknown function compare
PP_5698 +0.6 3.4 conserved exported protein of unknown function compare
PP_0979 +0.6 1.4 DNA polymerase III subunit chi compare
PP_1198 +0.6 1.3 transcriptional regulator, Cro/CI family (higA antitoxin like) compare
PP_2764 +0.6 1.3 FMN reductase (NADPH) compare
PP_4531 +0.6 1.9 conserved exported protein of unknown function compare
PP_1390 +0.6 1.1 conserved exported protein of unknown function compare
PP_1987 +0.6 0.4 Methlytransferase, UbiE/COQ5 family compare
PP_5557 +0.6 1.5 protein of unknown function compare
PP_5200 +0.6 3.3 proline aminopeptidase P II compare
PP_3392 +0.6 1.2 conserved protein of unknown function compare
PP_2873 +0.6 1.6 conserved protein of unknown function, UPF0145 family compare
PP_4238 +0.6 2.0 conserved protein of unknown function compare
PP_4354 +0.6 1.5 flagellar export apparatus subunit compare
PP_0886 +0.6 1.6 conserved exported protein of unknown function compare
PP_5730 +0.6 1.5 conserved protein of unknown function compare
PP_0533 +0.6 2.2 histidine kinase compare
PP_2898 +0.6 0.6 conserved exported protein of unknown function compare
PP_2816 +0.6 2.5 putative Transcriptional regulator NfxB compare
PP_5001 +0.6 1.3 protease HslVU, ATPase component compare
PP_5597 +0.5 1.4 conserved protein of unknown function compare
PP_4273 +0.5 0.6 Transcriptional regulator, MerR family compare
PP_2462 +0.5 1.5 conserved protein of unknown function compare
PP_2082 +0.5 3.5 phosphoenolpyruvate synthetase compare
PP_2054 +0.5 1.4 putative DNA-binding transcriptional regulator compare
PP_4936 +0.5 2.2 O-antigen polymerase compare
PP_5542 +0.5 2.1 protein of unknown function compare
PP_3508 +0.5 1.5 Protein CobW compare
PP_4365 +0.5 2.7 Flagellar protein FliJ compare
PP_1001 +0.5 2.0 arginine deiminase compare
PP_5076 +0.5 4.5 L-glutamate synthase(NADPH) alpha subunit compare
PP_3198 +0.5 0.9 Ferredoxin, 2Fe-2S compare
PP_0244 +0.5 2.5 conserved protein of unknown function compare
PP_2683 +0.5 2.5 putative sensory box histidine kinase/response regulator compare
PP_1364 +0.5 3.2 conserved exported protein of unknown function compare
PP_4197 +0.5 3.8 Transcriptional regulator, GntR family compare
PP_3378 +0.5 1.2 putative 2-ketogluconokinase compare
PP_3098 +0.5 0.7 conserved protein of unknown function compare
PP_5188 +0.5 2.4 putative transcriptional regulator (AsnC/Lrp family) compare
PP_3277 +0.5 1.8 ring 1,2-phenylacetyl-CoA epoxidase regulatory subunit compare
PP_2528 +0.5 1.7 O-acetylhomoserine (thiol)-lyase compare
PP_4892 +0.5 2.3 integral membrane ATP-dependent zinc metallopeptidase / HflK-HflC complex compare
PP_0959 +0.5 1.1 phospholipid ABC transporter compare
PP_1836 +0.5 1.8 putative metal transporter, ZIP family compare
PP_2189 +0.5 1.2 conserved protein of unknown function compare
PP_2848 +0.5 1.4 urease accessory protein compare
PP_2900 +0.5 1.7 conserved protein of unknown function compare
PP_4929 +0.5 1.5 Transcriptional regulator, LysR family compare
PP_2396 +0.5 1.0 conserved exported protein of unknown function compare
PP_2142 +0.5 1.9 Cell division inhibitor SulA compare
PP_4435 +0.5 1.6 conserved protein of unknown function compare
PP_0801 +0.5 0.8 conserved exported protein of unknown function compare
PP_5514 +0.5 2.2 conserved protein of unknown function compare
PP_2011 +0.5 1.7 conserved exported protein of unknown function compare
PP_4828 +0.5 0.7 Precorrin-8X methylmutase compare
PP_5184 +0.5 2.4 glutamylpolyamine synthetase compare
PP_4001 +0.5 2.4 Putative fluoride ion transporter CrcB compare
PP_2798 +0.5 1.7 putative Oxidoreductase compare
PP_0607 +0.5 1.8 putative Type IV pili biogenesis protein FimT compare
PP_4642 +0.5 1.0 Cyclic diguanosine monophosphate-binding protein compare
PP_4328 +0.5 1.4 conserved protein of unknown function compare
PP_4050 +0.5 3.8 glycogen synthase compare
PP_3846 +0.5 2.6 (R)-stereoselective amidase compare
PP_2197 +0.5 2.3 conserved exported protein of unknown function compare
PP_1207 +0.5 1.3 conserved protein of unknown function compare
PP_0679 +0.5 2.3 conserved exported protein of unknown function compare
PP_1242 +0.5 2.0 conserved protein of unknown function compare
PP_4253 +0.5 2.0 cytochrome c oxidase subunit, cbb3-type compare
PP_1167 +0.5 1.4 D-glucuronate / D-galacturonate TRAP transporter, large permease component (from data) compare
PP_3083 +0.5 2.5 putative Membrane protein compare
PP_3810 +0.5 1.0 conserved protein of unknown function compare
PP_5053 +0.5 1.9 Protein-export protein SecB compare
PP_0258 +0.5 1.1 regulator of murein cross-linking compare
PP_3107 +0.5 2.0 conserved protein of unknown function compare
PP_5723 +0.5 2.0 protein of unknown function compare
PP_1780 +0.5 4.1 putative mannosyltransferase compare
PP_2681 +0.5 1.1 coenzyme PQQ synthesis protein D compare
PP_4217 +0.5 4.4 outer membrane ferripyoverdine receptor FpvA, TonB-dependent compare
PP_1153 +0.5 1.6 putative lipoprotein compare
PP_2946 +0.5 2.2 peptidyl-tRNA hydrolase, ribosome rescue factor compare
PP_1051 +0.5 1.7 Type II secretion pathway protein XcpV compare
PP_0574 +0.5 3.5 DNA-binding response regulator, LuxR family compare
PP_2148 +0.5 3.1 transcription-repair coupling factor compare
PP_4832 +0.5 1.6 Precorrin-6x reductase compare
PP_2933 +0.5 2.5 GSH-dependent disulfide bond oxidoreductase compare
PP_4803 +0.5 3.3 D-alanyl-D-alanine carboxypeptidase compare
PP_1225 +0.5 1.6 7-carboxy-7-deazaguanine synthase compare
PP_1228 +0.5 2.2 Methyl-accepting chemotaxis transducer compare
PP_1799 +0.5 3.6 GDP-mannose 4,6-dehydratase compare
PP_1226 +0.5 1.5 pre-queuosine 0 synthase compare
PP_1554 +0.5 1.0 conserved protein of unknown function compare
PP_1386 +0.5 2.8 Probable efflux pump periplasmic linker TtgA compare


Specific Phenotypes

For 9 genes in this experiment

For carbon source 4-Methyl-2-oxovaleric acid in Pseudomonas putida KT2440

For carbon source 4-Methyl-2-oxovaleric acid across organisms