Experiment set15IT054 for Pseudomonas putida KT2440

Compare to:

Butyl stearate carbon source

200 most detrimental genes:

  gene name fitness t score description  
PP_1623 +2.1 16.7 RNA polymerase, sigma S (sigma 38) factor compare
PP_5145 +1.5 14.2 phosphoenolpyruvate-dependent regulator (with NPR and NTR proteins) compare
PP_0948 +1.4 6.0 Phosphocarrier protein HPr compare
PP_1799 +1.3 10.5 GDP-mannose 4,6-dehydratase compare
PP_1058 +1.3 11.3 conserved protein of unknown function compare
PP_4504 +1.2 0.9 conserved exported protein of unknown function compare
PP_1780 +1.1 10.5 putative mannosyltransferase compare
PP_4952 +1.1 2.5 ATP-dependent RNA helicase, specific for 23S rRNA compare
PP_4271 +1.1 1.3 conserved protein of unknown function compare
PP_0138 +1.1 7.3 conserved membrane protein of unknown function compare
PP_5008 +1.1 1.8 Poly granule-associated protein compare
PP_1410 +1.1 2.3 conserved protein of unknown function compare
PP_0547 +1.0 3.6 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase compare
PP_1293 +1.0 0.8 molybdopterin synthase small subunit compare
PP_2144 +1.0 3.5 Transcriptional regulator, TetR family compare
PP_1381 +0.9 1.5 4-carboxymuconolactone decarboxylase compare
PP_4227 +0.9 2.5 conserved protein of unknown function compare
PP_1004 +0.9 1.7 conserved protein of unknown function compare
PP_2581 +0.9 1.6 conserved protein of unknown function compare
PP_2764 +0.8 2.4 FMN reductase (NADPH) compare
PP_4517 +0.8 2.0 conserved protein of unknown function compare
PP_2060 +0.8 2.3 DNA-binding transcriptional dual regulator - SoxR-reversible one-electron oxidation of its [2Fe-2S] cluster, NADPH-dependent compare
PP_1776 +0.8 6.7 Mannose-6-phosphate isomerase/mannose-1-phosphate guanylyltransferase compare
PP_1803 +0.8 6.3 UDP-sugar epimerase compare
PP_2061 +0.8 2.6 conserved protein of unknown function compare
PP_4265 +0.7 2.5 DNA-binding transcriptional dual regulator compare
PP_1122 +0.7 2.2 OmpA family protein compare
PP_2067 +0.7 3.0 putative EmrB/QacA family drug resistance transporter compare
PP_4006 +0.7 5.6 Putative arginyl-tRNA--protein transferase compare
PP_5232 +0.7 1.6 conserved protein of unknown function compare
PP_5552 +0.7 2.5 conserved protein of unknown function compare
PP_2550 +0.7 2.1 putative transcriptional regulatory protein compare
PP_3883 +0.7 1.7 putative Phage holin compare
PP_1802 +0.7 6.2 glycosyl transferase compare
PP_1390 +0.7 1.8 conserved exported protein of unknown function compare
PP_2323 +0.7 5.4 conserved protein of unknown function compare
PP_1801 +0.7 5.0 Glycosyl transferase WbpY compare
PP_5561 +0.7 3.0 conserved protein of unknown function compare
PP_5106 +0.7 2.1 conserved inner membrane protein compare
PP_4159 +0.7 3.2 Potassium-transporting ATPase C chain compare
PP_0191 +0.7 2.6 Transcriptional regulatory protein AlgQ compare
PP_4874 +0.7 0.6 50S ribosomal protein L9 compare
PP_0240 +0.6 2.3 Aliphatic sulfonates import ATP-binding protein SsuB compare
PP_4308 +0.6 3.2 Transcriptional regulator, AsnC family compare
PP_1800 +0.6 4.6 Oxidoreductase Rmd compare
PP_1805 +0.6 5.6 Polysaccharide biosynthesis protein compare
PP_0540 +0.6 3.3 conserved inner membrane protein compare
PP_0893 +0.6 1.8 ThiJ/PfpI family protein compare
PP_3770 +0.6 1.5 conserved protein of unknown function compare
PP_4528 +0.6 1.8 conserved protein of unknown function compare
PP_2681 +0.6 1.9 coenzyme PQQ synthesis protein D compare
PP_2130 +0.6 3.9 putative Soluble lytic transglycosylase compare
PP_5168 +0.6 1.6 sulfate/thiosulfate import ATP-binding protein compare
PP_0874 +0.6 2.2 conserved protein of unknown function compare
PP_1512 +0.6 1.5 conserved protein of unknown function compare
PP_3892 +0.6 1.4 conserved protein of unknown function compare
PP_4337 +0.6 2.7 chemotaxis response regulator protein-glutamate methylesterase of group 1 operon compare
PP_4835 +0.6 1.4 conserved exported protein of unknown function compare
PP_0274 +0.6 1.8 putative transcriptional regulator containing HTH domain compare
PP_2835 +0.6 1.8 putative oxidoreductase compare
PP_1352 +0.6 1.5 UPF0234 protein PP_1352 compare
PP_1871 +0.6 3.2 Protease HtpX compare
PP_2737 +0.6 1.3 Oxidoreductase, short-chain dehydrogenase/reductase family compare
PP_5058 +0.5 2.9 Carboxy-terminal-processing protease compare
PP_4424 +0.5 2.2 Uncharacterized HTH-type transcriptional regulator y4tD compare
PP_2197 +0.5 2.6 conserved exported protein of unknown function compare
PP_5298 +0.5 1.5 putative glutamine amidotransferase compare
PP_4561 +0.5 0.9 stress response protein compare
PP_2027 +0.5 2.3 conserved exported protein of unknown function compare
PP_2335 +0.5 3.6 methylcitrate synthase compare
PP_0398 +0.5 2.7 Thiosulfate sulfurtransferase GlpE compare
PP_4847 +0.5 1.1 chaperone modulatory of CbpA co-chaperone protein compare
PP_5583 +0.5 1.3 conserved protein of unknown function compare
PP_2378 +0.5 1.1 Fe/S biogenesis protein NfuA compare
PP_0508 +0.5 2.5 conserved exported protein of unknown function compare
PP_2437 +0.5 3.3 putative Acyl-CoA dehydrogenase compare
PP_4961 +0.5 1.4 putative Lipoprotein compare
PP_1864 +0.5 2.3 conserved protein of unknown function compare
PP_2765 +0.5 1.2 putative Sulfonate monooxygenase MsuD compare
PP_5146 +0.5 2.8 RNA pyrophosphohydrolase compare
PP_5469 +0.5 2.3 putative SAM-dependent methyltransferase compare
PP_3447 +0.5 1.3 conserved membrane protein of unknown function compare
PP_1683 +0.5 1.6 Transcriptional regulator, MarR family compare
PP_3938 +0.5 0.7 conserved protein of unknown function compare
PP_0135 +0.5 2.0 conserved exported protein of unknown function compare
PP_4771 +0.5 1.9 conserved membrane protein of unknown function compare
PP_5144 +0.5 1.8 conserved protein of unknown function compare
PP_2389 +0.5 2.6 conserved protein of unknown function compare
PP_0132 +0.5 2.9 Alginate biosynthesis sensor protein KinB compare
PP_1074 +0.5 1.4 DNA-binding transcriptional repressor - GlpR-glycerol-3-phosphate compare
PP_4891 +0.5 1.6 integral membrane ATP-dependent zinc metallopeptidase / HflK-HflC complex compare
PP_0770 +0.5 2.5 PemI-like protein compare
PP_0841 +0.5 1.7 DNA-binding transcriptional dual regulator 2Fe-2S cluster IscR compare
PP_0103 +0.5 2.7 cytochrome c oxidase subunit 2 compare
PP_2648 +0.5 1.9 Universal stress protein family compare
PP_0152 +0.5 1.0 conserved exported protein of unknown function compare
PP_1164 +0.5 1.6 Transcriptional regulator, LysR family compare
PP_1836 +0.5 1.1 putative metal transporter, ZIP family compare
PP_2798 +0.5 2.1 putative Oxidoreductase compare
PP_4217 +0.5 4.4 outer membrane ferripyoverdine receptor FpvA, TonB-dependent compare
PP_1415 +0.5 2.0 putative membrane associated enzyme subunit compare
PP_2153 +0.5 1.9 conserved protein of unknown function compare
PP_4734 +0.5 2.8 DNA-binding transcriptional dual regulator, LldR-L-lactate compare
PP_1444 +0.5 3.4 quinoprotein glucose dehydrogenase compare
PP_5271 +0.5 2.9 DNA-binding transcriptional dual regulator, leucine-binding compare
PP_4828 +0.5 0.9 Precorrin-8X methylmutase compare
PP_4833 +0.5 1.8 SURF1 domain protein compare
PP_1513 +0.4 1.3 Ribosomal RNA small subunit methyltransferase J compare
PP_4803 +0.4 3.4 D-alanyl-D-alanine carboxypeptidase compare
PP_2878 +0.4 1.3 conserved protein of unknown function compare
PP_2793 +0.4 0.7 Acyl-CoA dehydrogenase family protein compare
PP_0821 +0.4 1.8 conserved exported protein of unknown function compare
PP_5626 +0.4 2.9 putative phage repressor-like, DNA-binding domain compare
PP_2611 +0.4 1.6 membrane protein of unknown function compare
PP_0273 +0.4 2.5 conserved protein of unknown function compare
PP_0319 +0.4 1.1 conserved protein of unknown function compare
PP_5522 +0.4 1.6 protein of unknown function compare
PP_5331 +0.4 2.1 Long-chain acyl-CoA thioester hydrolase compare
PP_3730 +0.4 0.9 Transcriptional regulatory protein AruR compare
PP_5675 +0.4 1.4 conserved protein of unknown function compare
PP_0254 +0.4 2.4 conserved protein of unknown function compare
PP_0236 +0.4 1.9 NAD(P)H-dependent FMN reductase subunit compare
PP_0781 +0.4 1.4 conserved protein of unknown function compare
PP_2672 +0.4 2.4 Transcriptional activator protein ExaE compare
PP_1855 +0.4 1.5 conserved exported protein of unknown function compare
PP_0357 +0.4 2.0 ACT domain protein compare
PP_3192 +0.4 1.6 conserved protein of unknown function compare
PP_1804 +0.4 2.6 Glycosyl transferase WbpL compare
PP_1605 +0.4 1.8 Ribonuclease HII compare
PP_0905 +0.4 1.2 conserved exported protein of unknown function compare
PP_3799 +0.4 1.6 conserved exported protein of unknown function compare
PP_4844 +0.4 1.7 putative Urea ABC transporter, ATP-binding protein compare
PP_4102 +0.4 1.0 conserved protein of unknown function compare
PP_0610 +0.4 1.8 conserved exported protein of unknown function compare
PP_3797 +0.4 1.9 conserved membrane protein of unknown function compare
PP_5051 +0.4 1.3 conserved protein of unknown function compare
PP_3060 +0.4 2.2 putative tail sheath protein compare
PP_2705 +0.4 0.9 conserved protein of unknown function compare
PP_4697 +0.4 1.1 poly(A) polymerase compare
PP_1650 +0.4 3.8 Sensor protein GacS compare
PP_0725 +0.4 2.0 conserved hypothetical TPR repeat protein compare
PP_3064 +0.4 1.3 Phage tail protein compare
PP_2196 +0.4 1.3 agmatinase compare
PP_3765 +0.4 1.7 H-NS family protein MvaT compare
PP_5648 +0.4 1.6 conserved exported protein of unknown function compare
PP_1824 +0.4 0.9 Smr domain protein compare
PP_2313 +0.4 1.3 conserved membrane protein of unknown function compare
PP_2646 +0.4 1.3 conserved protein of unknown function compare
PP_5131 +0.4 2.4 sodium-cystine symporter compare
PP_5201 +0.4 0.7 conserved protein of unknown function, UPF0149 family compare
PP_4166 +0.4 1.7 conserved protein of unknown function compare
PP_2846 +0.4 1.5 urease accessory protein compare
PP_2121 +0.4 1.1 putative Lipoprotein compare
PP_0361 +0.4 1.3 putative Competence protein ComF compare
PP_5537 +0.4 1.2 conserved membrane protein of unknown function compare
PP_2700 +0.4 0.7 AhpC/TSA family protein compare
PP_2677 +0.4 1.2 conserved exported protein of unknown function compare
PP_5644 +0.4 1.6 conserved membrane protein of unknown function compare
PP_4296 +0.4 0.8 conserved exported protein of unknown function compare
PP_0306 +0.4 1.3 conserved protein of unknown function compare
PP_4196 +0.4 1.4 conserved exported protein of unknown function compare
PP_4871 +0.4 1.6 putative lysine decarboxylase family protein compare
PP_1893 +0.4 2.6 medium-long chain acyl-CoA dehydrogenase compare
PP_2319 +0.4 2.5 conserved protein of unknown function compare
PP_1104 +0.4 2.1 AotO-related protein compare
PP_5505 +0.4 1.2 conserved transmembrane protein of unknown function compare
PP_3749 +0.4 1.9 conserved protein of unknown function compare
PP_3228 +0.4 1.8 putative Periplasmic aliphatic sulfonate-binding protein compare
PP_3899 +0.4 0.8 conserved protein of unknown function, hicB family compare
PP_5481 +0.4 2.0 conserved protein of unknown function compare
PP_t12 +0.4 0.6 tRNA-Thr compare
PP_1867 +0.4 1.6 conserved protein of unknown function compare
PP_5580 +0.4 0.7 protein of unknown function compare
PP_3935 +0.4 1.1 conserved protein of unknown function compare
PP_5083 +0.4 1.2 putative Type IV pili biogenesis protein PilM compare
PP_5039 +0.4 0.8 conserved protein of unknown function compare
PP_5093 +0.4 0.5 twitching motility protein compare
PP_2741 +0.4 2.4 conserved membrane protein of unknown function compare
PP_4792 +0.4 1.5 conserved exported protein of unknown function compare
PP_2597 +0.3 1.3 conserved protein of unknown function compare
PP_1550 +0.3 1.7 Transcriptional regulator, Cro/CI family compare
PP_0380 +0.3 2.1 Coenzyme PQQ synthesis protein A compare
PP_2342 +0.3 1.2 conserved protein of unknown function compare
PP_1113 +0.3 2.0 Pyridoxal-phosphate dependent enzyme family protein compare
PP_5001 +0.3 1.3 protease HslVU, ATPase component compare
PP_3179 +0.3 1.1 Transcriptional regulator, LysR family compare
PP_0211 +0.3 2.3 conserved protein of unknown function compare
PP_3052 +0.3 0.6 conserved protein of unknown function compare
PP_1198 +0.3 1.4 transcriptional regulator, Cro/CI family (higA antitoxin like) compare
PP_2528 +0.3 1.6 O-acetylhomoserine (thiol)-lyase compare
PP_1829 +0.3 1.4 Hydrolase, alpha/beta fold family compare
PP_2320 +0.3 2.9 conserved exported protein of unknown function compare
PP_2227 +0.3 1.7 putative Multicomponent potassium-proton antiporter, subunit E compare
PP_1890 +0.3 2.0 Type 1 pili chaperone protein FimC compare
PP_3219 +0.3 1.9 putative Alkansulfonate monooxygenase compare
PP_1509 +0.3 2.1 conserved protein of unknown function compare
PP_5337 +0.3 1.6 LysR family transcriptional regulator compare
PP_4268 +0.3 0.5 nucleoid-associated broad specificity regulator compare
PP_0628 +0.3 1.7 conserved protein of unknown function compare
PP_0106 +0.3 2.3 cytochrome c oxidase subunit 3 compare


Specific Phenotypes

For 5 genes in this experiment

For carbon source Butyl stearate in Pseudomonas putida KT2440

For carbon source Butyl stearate across organisms