Experiment set14IT019 for Escherichia coli BW25113

Compare to:

LB

200 most important genes:

  gene name fitness t score description  
b2512 yfgL -3.3 -3.8 protein assembly complex, lipoprotein component (NCBI) compare
b1192 ldcA -2.7 -3.9 L,D-carboxypeptidase A (NCBI) compare
b2431 b2431 -2.7 -6.8 orf, hypothetical protein (VIMSS) compare
b3405 ompR -2.4 -1.7 osmolarity response regulator (NCBI) compare
b2215 ompC -2.2 -7.3 outer membrane porin protein C (NCBI) compare
b1863 ruvC -2.2 -1.4 Holliday junction resolvase (NCBI) compare
b1476 fdnI -2.1 -1.7 formate dehydrogenase-N, cytochrome B556 (gamma) subunit, nitrate-inducible (NCBI) compare
b3839 tatC -2.1 -4.2 TatABCE protein translocation system subunit (NCBI) compare
b0741 pal -2.0 -2.6 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b0088 murD -2.0 -2.2 UDP-N-acetylmuramoyl-L-alanyl-D-glutamatesynthetase (NCBI) compare
b0688 pgm -1.9 -1.8 phosphoglucomutase (NCBI) compare
b2017 yefM -1.9 -1.2 orf, hypothetical protein (VIMSS) compare
b1942 fliJ -1.9 -1.3 flagellar biosynthesis chaperone (NCBI) compare
b1090 plsX -1.9 -5.1 glycerolphosphate auxotrophy in plsB background (VIMSS) compare
b4242 mgtA -1.9 -1.3 magnesium transporter (NCBI) compare
b0019 nhaA -1.8 -7.3 pH-dependent sodium/proton antiporter (NCBI) compare
b0053 surA -1.7 -1.7 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b3652 recG -1.7 -6.5 ATP-dependent DNA helicase (NCBI) compare
b0740 tolB -1.7 -3.0 translocation protein TolB precursor (NCBI) compare
b0439 lon -1.7 -2.2 DNA-binding ATP-dependent protease La (NCBI) compare
b1304 pspA -1.7 -2.5 regulatory protein for phage-shock-protein operon (NCBI) compare
b3778 rep -1.7 -4.9 DNA helicase and single-stranded DNA-dependent ATPase (NCBI) compare
b1830 prc -1.6 -4.2 carboxy-terminal protease for penicillin-binding protein 3 (NCBI) compare
b3026 qseC -1.6 -1.1 sensory histidine kinase in two-component regulatory system with QseB (NCBI) compare
b3390 aroK -1.5 -2.3 shikimate kinase I (NCBI) compare
b3229 sspA -1.5 -1.7 stringent starvation protein A (NCBI) compare
b2518 ndk -1.5 -2.0 nucleoside diphosphate kinase (NCBI) compare
b4171 miaA -1.5 -1.0 tRNA delta(2)-isopentenylpyrophosphate transferase (NCBI) compare
b3404 envZ -1.5 -7.0 osmolarity sensor protein (NCBI) compare
b3962 udhA -1.5 -3.0 putative oxidoreductase (VIMSS) compare
b4481 rffT -1.5 -4.7 4-alpha-L-fucosyltransferase (NCBI) compare
b1540 ydfH -1.4 -2.3 predicted DNA-binding transcriptional regulator (NCBI) compare
b2282 nuoH -1.4 -2.7 NADH dehydrogenase subunit H (NCBI) compare
b0957 ompA -1.4 -2.5 outer membrane protein A (3a;II*;G;d) (NCBI) compare
b1175 minD -1.4 -3.3 membrane ATPase of the MinC-MinD-MinE system (NCBI) compare
b2808 gcvA -1.4 -2.7 DNA-binding transcriptional dual regulator (NCBI) compare
b4603 rseX -1.4 -0.7 sRNA regulating ompA and ompC translation, with Hfq (RefSeq) compare
b2576 srmB -1.4 -2.1 ATP-dependent RNA helicase (NCBI) compare
b1865 nudB -1.3 -1.3 dATP pyrophosphohydrolase (NCBI) compare
b0014 dnaK -1.3 -1.9 molecular chaperone DnaK (NCBI) compare
b3387 dam -1.3 -7.0 DNA adenine methylase (NCBI) compare
b2280 nuoJ -1.3 -3.9 NADH dehydrogenase subunit J (NCBI) compare
b4685 yrbN -1.3 -2.0 expressed protein (RefSeq) compare
b3863 polA -1.3 -0.8 DNA polymerase I (NCBI) compare
b1185 dsbB -1.3 -2.8 reoxidizes DsbA protein following formation of disulfide bond in P-ring of flagella. (VIMSS) compare
b3613 yibP -1.3 -1.9 putative membrane protein (VIMSS) compare
b1292 sapC -1.3 -1.8 predicted antimicrobial peptide transporter subunit (NCBI) compare
b3977 tyrU -1.3 -1.2 tRNA-Tyr (NCBI) compare
b2285 nuoE -1.2 -1.6 NADH dehydrogenase subunit E (NCBI) compare
b3838 tatB -1.2 -4.7 sec-independent translocase (NCBI) compare
b1109 ndh -1.2 -3.4 respiratory NADH dehydrogenase 2/cupric reductase (NCBI) compare
b3650 spoT -1.2 -4.5 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (NCBI) compare
b3636 rpmG -1.2 -1.5 50S ribosomal protein L33 (NCBI) compare
b1847 yebF -1.2 -1.4 predicted protein (RefSeq) compare
b3792 wzxE -1.2 -3.7 O-antigen translocase (NCBI) compare
b0560 nohB -1.2 -2.2 DLP12 prophage; DNA packaging protein (NCBI) compare
b2830 nudH -1.2 -0.8 dinucleoside polyphosphate hydrolase (NCBI) compare
b1685 ydiH -1.1 -1.3 predicted protein (RefSeq) compare
b3443 yrhA -1.1 -1.5 orf, hypothetical protein (VIMSS) compare
b4436 ryeC -1.1 -1.3 Novel sRNA, function unknown; paralogous to the other QUAD sRNA genes unknown (RefSeq) compare
b0814 ompX -1.1 -2.4 outer membrane protein X (NCBI) compare
b0472 recR -1.1 -4.8 recombination protein RecR (NCBI) compare
b1085 b1085 -1.1 -1.8 orf, hypothetical protein (VIMSS) compare
b2175 spr -1.1 -2.5 predicted peptidase, outer membrane lipoprotein (NCBI) compare
b1293 sapB -1.1 -1.2 predicted antimicrobial peptide transporter subunit (NCBI) compare
b0149 mrcB -1.1 -6.5 penicillin-binding protein 1b (NCBI) compare
b1758 b1758 -1.1 -1.5 putative cytochrome oxidase (VIMSS) compare
b1095 fabF -1.1 -4.7 3-oxoacyl-(acyl carrier protein) synthase (NCBI) compare
b3644 yicC -1.1 -3.9 hypothetical protein (NCBI) compare
b2565 recO -1.1 -3.4 DNA repair protein RecO (NCBI) compare
b3791 rffA -1.1 -3.8 TDP-4-oxo-6-deoxy-D-glucose transaminase (NCBI) compare
b0605 ahpC -1.1 -2.9 alkyl hydroperoxide reductase, C22 subunit (NCBI) compare
b2912 ygfA -1.0 -2.4 putative ligase (VIMSS) compare
b2951 yggS -1.0 -3.0 predicted enzyme (NCBI) compare
b4042 dgkA -1.0 -1.5 diacylglycerol kinase (NCBI) compare
b1874 cutC -1.0 -2.0 copper homeostasis protein (NCBI) compare
b1161 ycgX -1.0 -0.6 hypothetical protein (NCBI) compare
b2424 cysU -1.0 -1.8 sulfate/thiosulfate transporter subunit (NCBI) compare
b3935 priA -1.0 -1.9 primosome assembly protein PriA (NCBI) compare
b3181 greA -1.0 -2.8 transcription elongation factor: cleaves 3' nucleotide of paused mRNA (VIMSS) compare
b3035 tolC -1.0 -4.6 outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes (VIMSS) compare
b0247 ykfG -1.0 -0.9 CP4-6 prophage; predicted DNA repair protein (NCBI) compare
b0737 tolQ -1.0 -1.2 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b1279 yciS -1.0 -1.0 conserved inner membrane protein (NCBI) compare
b3052 rfaE -1.0 -2.7 fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) compare
b1357 ydaS -0.9 -1.3 Rac prophage; predicted DNA-binding transcriptional regulator (NCBI) compare
b1520 b1520 -0.9 -2.4 orf, hypothetical protein (VIMSS) compare
b3620 rfaF -0.9 -2.5 ADP-heptose:LPS heptosyltransferase II (NCBI) compare
b3609 secB -0.9 -2.5 export protein SecB (NCBI) compare
b3726 pstA -0.9 -2.5 phosphate transporter subunit (NCBI) compare
b0739 tolA -0.9 -1.0 cell envelope integrity inner membrane protein TolA (NCBI) compare
b2620 smpB -0.9 -0.7 SsrA-binding protein (NCBI) compare
b1984 asnW -0.9 -1.3 tRNA-Asn (NCBI) compare
b1749 xthA -0.9 -2.2 exonuclease III (NCBI) compare
b0051 ksgA -0.9 -2.1 dimethyladenosine transferase (NCBI) compare
b4568 ytjA -0.9 -1.7 predicted protein (RefSeq) compare
b2277 nuoM -0.9 -3.1 NADH dehydrogenase subunit M (NCBI) compare
b2910 zapA -0.9 -2.9 protein that localizes to the cytokinetic ring (NCBI) compare
b1861 ruvA -0.9 -0.5 Holliday junction DNA helicase motor protein (NCBI) compare
b4509 ylcG -0.9 -1.3 DLP12 prophage; predicted protein (NCBI) compare
b1765 ydjA -0.9 -0.7 predicted oxidoreductase (NCBI) compare
b4217 ytfK -0.9 -2.9 orf, hypothetical protein (VIMSS) compare
b4533 ynfO -0.9 -1.2 Qin prophage; predicted protein (NCBI) compare
b3700 recF -0.9 -5.2 recombination protein F (NCBI) compare
b0092 ddlB -0.8 -2.6 D-alanylalanine synthetase (NCBI) compare
b3341 rpsG -0.8 -0.6 30S ribosomal protein S7 (NCBI) compare
b4163 glyV -0.8 -1.2 tRNA-Gly (NCBI) compare
b4203 rplI -0.8 -2.1 50S ribosomal protein L9 (NCBI) compare
b3790 rffC -0.8 -2.4 TDP-fucosamine acetyltransferase (RefSeq) compare
b4453 ldrD -0.8 -1.7 toxic polypeptide, small (NCBI) compare
b0438 clpX -0.8 -3.2 ATP-dependent protease ATP-binding subunit (NCBI) compare
b0263 afuB -0.8 -1.8 CP4-6 prophage; predicted ferric trasnporter subunit (RefSeq) compare
b4179 vacB -0.8 -2.6 putative enzyme (VIMSS) compare
b1502 ydeQ -0.8 -1.0 predicted fimbrial-like adhesin protein (NCBI) compare
b2080 b2080 -0.8 -1.2 orf, hypothetical protein (VIMSS) compare
b1730 ydjO -0.8 -0.5 predicted protein (RefSeq) compare
b0161 degP -0.8 -4.1 serine endoprotease (protease Do), membrane-associated (NCBI) compare
b1684 sufA -0.8 -1.1 iron-sulfur cluster assembly scaffold protein (NCBI) compare
b2618 b2618 -0.8 -2.2 orf, hypothetical protein (VIMSS) compare
b0890 ftsK -0.8 -1.1 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b4630 ykgP -0.8 -1.4 no description compare
b0843 ybjH -0.8 -1.2 hypothetical protein (NCBI) compare
b0738 tolR -0.8 -1.0 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b0802 ybiJ -0.8 -1.6 hypothetical protein (NCBI) compare
b4594 ymgJ -0.8 -1.2 hypothetical protein (RefSeq) compare
b0119 yacL -0.8 -4.2 orf, hypothetical protein (VIMSS) compare
b2432 yfeY -0.8 -1.3 hypothetical protein (NCBI) compare
b2617 smpA -0.8 -1.5 small membrane protein A (VIMSS) compare
b1630 rsxD -0.8 -2.5 electron transport complex protein RnfD (NCBI) compare
b1920 fliY -0.8 -1.3 cystine transporter subunit (NCBI) compare
b4441 glmY -0.8 -1.2 sRNA activator of glmS mRNA (RefSeq) compare
b1183 umuD -0.8 -0.9 DNA polymerase V, subunit D (NCBI) compare
b3180 yhbY -0.8 -2.8 predicted RNA-binding protein (NCBI) compare
b0125 hpt -0.8 -2.6 hypoxanthine phosphoribosyltransferase (VIMSS) compare
b3493 pitA -0.7 -2.7 phosphate transporter, low-affinity (NCBI) compare
b3813 uvrD -0.7 -5.3 DNA-dependent ATPase I and helicase II (NCBI) compare
b4634 ylcF -0.7 -2.1 no description compare
b3786 rffE -0.7 -4.7 UDP-N-acetyl glucosamine-2-epimerase (NCBI) compare
b1164 ycgZ -0.7 -0.8 hypothetical protein (NCBI) compare
b3260 dusB -0.7 -2.9 tRNA-dihydrouridine synthase B (NCBI) compare
b1712 ihfA -0.7 -0.9 integration host factor subunit alpha (NCBI) compare
b4201 priB -0.7 -1.5 primosomal replication protein N (NCBI) compare
b1159 mcrA -0.7 -0.4 e14 prophage; 5-methylcytosine-specific restriction endonuclease B (NCBI) compare
b1506 yneL -0.7 -0.7 predicted transcriptional regulator (NCBI) compare
b4596 yciZ -0.7 -1.0 hypothetical protein (RefSeq) compare
b2195 ccmG -0.7 -1.6 periplasmic thioredoxin of cytochrome c-type biogenesis (NCBI) compare
b1669 ydhT -0.7 -1.3 hypothetical protein (NCBI) compare
b1594 dgsA -0.7 -1.7 DNA-binding transcriptional repressor (NCBI) compare
b3950 frwB -0.7 -1.6 predicted enzyme IIB component of PTS (NCBI) compare
b3842 rfaH -0.7 -2.4 transcriptional activator RfaH (NCBI) compare
b1503 ydeR -0.7 -1.1 predicted fimbrial-like adhesin protein (NCBI) compare
b3787 rffD -0.7 -4.0 UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase (NCBI) compare
b4208 cycA -0.7 -4.0 D-alanine/D-serine/glycine transporter (NCBI) compare
b3961 oxyR -0.7 -4.0 DNA-binding transcriptional dual regulator (NCBI) compare
b2892 recJ -0.7 -3.7 ssDNA exonuclease, 5' --> 3'-specific (NCBI) compare
b2450 yffS -0.7 -1.3 CPZ-55 prophage; predicted protein (RefSeq) compare
b3761 trpT -0.7 -1.1 tRNA-Trp (NCBI) compare
b1855 lpxM -0.7 -2.2 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase (NCBI) compare
b0623 cspE -0.7 -1.0 cold shock protein E (NCBI) compare
b2894 xerD -0.7 -0.4 site-specific tyrosine recombinase XerD (NCBI) compare
b1846 yebE -0.7 -2.1 hypothetical protein (NCBI) compare
b1853 yebK -0.7 -1.4 predicted DNA-binding transcriptional regulator (NCBI) compare
b2390 ypeC -0.7 -2.1 hypothetical protein (NCBI) compare
b2340 sixA -0.7 -1.6 phosphohistidine phosphatase (NCBI) compare
b3205 yhbJ -0.7 -1.8 hypothetical protein (NCBI) compare
b2614 grpE -0.7 -1.1 heat shock protein (NCBI) compare
b4410 ecnA -0.7 -1.1 entericidin A membrane lipoprotein, antidote entericidin B (NCBI) compare
b3250 mreC -0.7 -0.8 cell wall structural complex MreBCD transmembrane component MreC (NCBI) compare
b4246 pyrL -0.7 -1.2 pyrBI operon leader peptide (NCBI) compare
b3915 fieF -0.7 -4.2 ferrous iron efflux protein F (NCBI) compare
b1763 topB -0.7 -2.1 DNA topoisomerase III (NCBI) compare
b3784 rfe -0.7 -4.2 UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase (NCBI) compare
b2082 ogrK -0.7 -1.3 DNA-binding transcriptional regulator prophage P2 remnant (NCBI) compare
b0720 gltA -0.7 -2.7 citrate synthase (NCBI) compare
b0407 yajC -0.7 -1.1 preprotein translocase subunit YajC (NCBI) compare
b1333 uspE -0.7 -1.7 stress-induced protein (NCBI) compare
b2007 yeeX -0.6 -1.7 conserved protein (RefSeq) compare
b0649 djlC -0.6 -2.7 Hsc56 co-chaperone of HscC (NCBI) compare
b1742 b1742 -0.6 -1.4 orf, hypothetical protein (VIMSS) compare
b1171 b1171 -0.6 -1.1 orf, hypothetical protein (VIMSS) compare
b3247 cafA -0.6 -3.9 bundles of cytoplasmic filaments (VIMSS) compare
b1708 nlpC -0.6 -2.0 predicted lipoprotein (NCBI) compare
b1505 ydeT -0.6 -0.6 hypothetical protein (RefSeq) compare
b3292 zntR -0.6 -1.4 zinc-responsive transcriptional regulator (NCBI) compare
b0931 pncB -0.6 -2.2 nicotinate phosphoribosyltransferase (NCBI) compare
b3836 b3836 -0.6 -2.0 orf, hypothetical protein (VIMSS) compare
b2250 b2250 -0.6 -1.8 orf, hypothetical protein (VIMSS) compare
b4546 ypeB -0.6 -0.8 hypothetical protein (NCBI) compare
b2699 recA -0.6 -0.4 recombinase A (NCBI) compare
b0412 yajI -0.6 -2.1 orf, hypothetical protein (VIMSS) compare
b1545 pinQ -0.6 -0.3 Qin prophage; predicted site-specific recombinase (NCBI) compare
b1551 b1551 -0.6 -0.3 orf, hypothetical protein (VIMSS) compare
b3150 yraP -0.6 -2.5 hypothetical protein (NCBI) compare
b2284 nuoF -0.6 -1.3 NADH:ubiquinone oxidoreductase, chain F (NCBI) compare
b0437 clpP -0.6 -1.9 ATP-dependent Clp protease proteolytic subunit (NCBI) compare
b0955 ycbZ -0.6 -3.0 predicted peptidase (NCBI) compare
b3794 rffM -0.6 -2.6 putative UDP-N-acetyl-D-mannosaminuronic acid transferase (NCBI) compare
b1360 ydaV -0.6 -1.4 Rac prophage; predicted DNA replication protein (NCBI) compare
b3101 yqjF -0.6 -1.6 orf, hypothetical protein (VIMSS) compare
b4418 sraB -0.6 -1.0 unknown RNA (NCBI) compare


Specific Phenotypes

For 1 genes in this experiment