| | gene | name | fitness | t score | description | |
|---|
| b3035 | tolC | -5.9 | -5.8 | outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes (VIMSS) | compare |
| b1855 | lpxM | -5.9 | -5.7 | lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase (NCBI) | compare |
| b2346 | vacJ | -5.8 | -8.0 | predicted lipoprotein (NCBI) | compare |
| b0178 | hlpA | -5.7 | -6.7 | periplasmic chaperone (NCBI) | compare |
| b0463 | acrA | -5.6 | -13.5 | multidrug efflux system (NCBI) | compare |
| b2617 | smpA | -5.4 | -5.2 | small membrane protein A (VIMSS) | compare |
| b0462 | acrB | -5.2 | -21.8 | multidrug efflux system protein (NCBI) | compare |
| b2494 | yfgC | -5.0 | -11.2 | predicted peptidase (NCBI) | compare |
| b3199 | yrbK | -4.9 | -3.4 | hypothetical protein (NCBI) | compare |
| b0957 | ompA | -4.7 | -4.6 | outer membrane protein A (3a;II*;G;d) (NCBI) | compare |
| b2512 | yfgL | -4.7 | -7.2 | protein assembly complex, lipoprotein component (NCBI) | compare |
| b3163 | nlpI | -4.6 | -5.4 | hypothetical protein (NCBI) | compare |
| b4201 | priB | -4.5 | -4.1 | primosomal replication protein N (NCBI) | compare |
| b1830 | prc | -4.2 | -4.9 | carboxy-terminal protease for penicillin-binding protein 3 (NCBI) | compare |
| b0222 | lpcA | -4.0 | -2.8 | phosphoheptose isomerase (NCBI) | compare |
| b3195 | yrbF | -4.0 | -14.9 | predicted toluene transporter subunit: ATP-binding component of ABC superfamily (NCBI) | compare |
| b0053 | surA | -3.9 | -2.7 | peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) | compare |
| b3194 | yrbE | -3.8 | -13.7 | predicted toluene transporter subunit: membrane component of ABC superfamily (NCBI) | compare |
| b3842 | rfaH | -3.7 | -8.0 | transcriptional activator RfaH (NCBI) | compare |
| b3192 | yrbC | -3.7 | -13.3 | predicted ABC-type organic solvent transporter (NCBI) | compare |
| b3193 | yrbD | -3.7 | -13.1 | predicted ABC-type organic solvent transporter (NCBI) | compare |
| b0688 | pgm | -3.7 | -2.6 | phosphoglucomutase (NCBI) | compare |
| b3631 | rfaG | -3.6 | -12.8 | glucosyltransferase I (NCBI) | compare |
| b1236 | galU | -3.5 | -3.4 | glucose-1-phosphate uridylyltransferase (NCBI) | compare |
| b3792 | wzxE | -3.5 | -6.3 | O-antigen translocase (NCBI) | compare |
| b3621 | rfaC | -3.4 | -2.3 | ADP-heptose:LPS heptosyl transferase I (NCBI) | compare |
| b3052 | rfaE | -3.4 | -6.0 | fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) | compare |
| b3619 | rfaD | -3.3 | -3.2 | ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) | compare |
| b3620 | rfaF | -3.2 | -5.3 | ADP-heptose:LPS heptosyltransferase II (NCBI) | compare |
| b3026 | qseC | -3.1 | -2.1 | sensory histidine kinase in two-component regulatory system with QseB (NCBI) | compare |
| b0740 | tolB | -3.0 | -4.1 | translocation protein TolB precursor (NCBI) | compare |
| b1176 | minC | -2.9 | -4.7 | septum formation inhibitor (NCBI) | compare |
| b3191 | yrbB | -2.8 | -9.8 | orf, hypothetical protein (VIMSS) | compare |
| b1346 | ydaQ | -2.8 | -2.6 | orf, hypothetical protein (VIMSS) | compare |
| b2174 | b2174 | -2.7 | -9.8 | orf, hypothetical protein (VIMSS) | compare |
| b3935 | priA | -2.7 | -4.1 | primosome assembly protein PriA (NCBI) | compare |
| b3632 | rfaQ | -2.7 | -19.5 | lipopolysaccharide core biosynthesis protein (NCBI) | compare |
| b2317 | dedA | -2.7 | -7.5 | conserved inner membrane protein (NCBI) | compare |
| b0912 | ihfB | -2.6 | -4.4 | integration host factor subunit beta (NCBI) | compare |
| b3628 | rfaB | -2.6 | -9.1 | UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase (RefSeq) | compare |
| b3630 | rfaP | -2.6 | -9.8 | kinase that phosphorylates core heptose of lipopolysaccharide (NCBI) | compare |
| b3652 | recG | -2.5 | -11.8 | ATP-dependent DNA helicase (NCBI) | compare |
| b3627 | rfaI | -2.4 | -9.7 | UDP-D-galactose:(glucosyl)lipopolysaccharide- alpha-1,3-D-galactosyltransferase (NCBI) | compare |
| b2509 | xseA | -2.4 | -10.9 | exodeoxyribonuclease VII large subunit (NCBI) | conserved |
| b0049 | apaH | -2.4 | -4.3 | diadenosinetetraphosphatase (NCBI) | compare |
| b0739 | tolA | -2.4 | -4.2 | cell envelope integrity inner membrane protein TolA (NCBI) | compare |
| b2616 | recN | -2.3 | -10.1 | recombination and repair protein (NCBI) | conserved |
| b2215 | ompC | -2.2 | -10.2 | outer membrane porin protein C (NCBI) | compare |
| b1863 | ruvC | -2.2 | -2.5 | Holliday junction resolvase (NCBI) | compare |
| b0759 | galE | -2.2 | -6.8 | UDP-galactose-4-epimerase (VIMSS) | compare |
| b0145 | dksA | -2.2 | -3.5 | DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) | compare |
| b0623 | cspE | -2.1 | -3.0 | cold shock protein E (NCBI) | compare |
| b1175 | minD | -2.1 | -6.2 | membrane ATPase of the MinC-MinD-MinE system (NCBI) | compare |
| b2572 | rseA | -2.1 | -4.2 | anti-sigma factor (NCBI) | compare |
| b3784 | rfe | -2.1 | -13.5 | UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase (NCBI) | compare |
| b3860 | dsbA | -2.1 | -10.9 | periplasmic protein disulfide isomerase I (NCBI) | compare |
| b3609 | secB | -2.0 | -5.4 | export protein SecB (NCBI) | compare |
| b1861 | ruvA | -2.0 | -1.3 | Holliday junction DNA helicase motor protein (NCBI) | compare |
| b4402 | yjjY | -1.9 | -1.6 | hypothetical protein (NCBI) | compare |
| b1831 | proQ | -1.8 | -3.2 | putative solute/DNA competence effector (NCBI) | compare |
| b2571 | rseB | -1.8 | -8.3 | periplasmic negative regulator of sigmaE (NCBI) | compare |
| b0436 | tig | -1.8 | -9.8 | trigger factor (NCBI) | compare |
| b4481 | rffT | -1.7 | -8.0 | 4-alpha-L-fucosyltransferase (NCBI) | compare |
| b1677 | lpp | -1.7 | -3.6 | murein lipoprotein (NCBI) | compare |
| b4146 | yjeK | -1.7 | -2.0 | predicted lysine aminomutase (NCBI) | compare |
| b3790 | rffC | -1.7 | -6.4 | TDP-fucosamine acetyltransferase (RefSeq) | compare |
| b0741 | pal | -1.7 | -4.0 | peptidoglycan-associated outer membrane lipoprotein (NCBI) | compare |
| b3613 | yibP | -1.6 | -3.4 | putative membrane protein (VIMSS) | compare |
| b3387 | dam | -1.6 | -10.6 | DNA adenine methylase (NCBI) | compare |
| b2567 | rnc | -1.6 | -1.1 | ribonuclease III (NCBI) | compare |
| b0737 | tolQ | -1.6 | -2.9 | membrane spanning protein in TolA-TolQ-TolR complex (NCBI) | compare |
| b0738 | tolR | -1.6 | -2.9 | membrane spanning protein in TolA-TolQ-TolR complex (NCBI) | compare |
| b3778 | rep | -1.5 | -8.3 | DNA helicase and single-stranded DNA-dependent ATPase (NCBI) | compare |
| b0877 | ybjX | -1.5 | -5.8 | hypothetical protein (NCBI) | compare |
| b0014 | dnaK | -1.5 | -2.2 | molecular chaperone DnaK (NCBI) | compare |
| b1860 | ruvB | -1.5 | -1.0 | Holliday junction DNA helicase B (NCBI) | compare |
| b3082 | ygjM | -1.5 | -2.3 | predicted DNA-binding transcriptional regulator (NCBI) | compare |
| b2188 | yejM | -1.5 | -8.6 | predicted hydrolase, inner membrane (NCBI) | compare |
| b3803 | hemX | -1.4 | -9.1 | predicted uroporphyrinogen III methylase (NCBI) | compare |
| b3791 | rffA | -1.4 | -6.3 | TDP-4-oxo-6-deoxy-D-glucose transaminase (NCBI) | compare |
| b3764 | yifE | -1.4 | -5.3 | hypothetical protein (NCBI) | compare |
| b0149 | mrcB | -1.4 | -9.8 | penicillin-binding protein 1b (NCBI) | compare |
| b3839 | tatC | -1.4 | -7.2 | TatABCE protein translocation system subunit (NCBI) | compare |
| b3405 | ompR | -1.4 | -4.9 | osmolarity response regulator (NCBI) | compare |
| b0200 | gmhB | -1.4 | -0.9 | hypothetical protein (NCBI) | compare |
| b1125 | potB | -1.3 | -4.0 | spermidine/putrescine ABC transporter membrane protein (NCBI) | compare |
| b1604 | ydgH | -1.3 | -6.3 | hypothetical protein (NCBI) | compare |
| b3261 | fis | -1.3 | -2.1 | DNA-binding protein Fis (NCBI) | compare |
| b0685 | ybfE | -1.3 | -3.5 | orf, hypothetical protein (VIMSS) | compare |
| b4702 | mgtL | -1.3 | -2.2 | regulatory leader peptide for mgtA (NCBI) | compare |
| b3786 | rffE | -1.3 | -9.0 | UDP-N-acetyl glucosamine-2-epimerase (NCBI) | compare |
| b2620 | smpB | -1.3 | -1.9 | SsrA-binding protein (NCBI) | compare |
| b2642 | yfjW | -1.2 | -1.2 | CP4-57 prophage; predicted inner membrane protein (NCBI) | compare |
| b4529 | ydbJ | -1.2 | -1.4 | hypothetical protein (NCBI) | compare |
| b3787 | rffD | -1.2 | -7.9 | UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase (NCBI) | compare |
| b2954 | yggV | -1.2 | -5.4 | putative deoxyribonucleotide triphosphate pyrophosphatase (NCBI) | compare |
| b1764 | selD | -1.2 | -5.3 | selenophosphate synthetase (NCBI) | compare |
| b2945 | endA | -1.2 | -4.6 | DNA-specific endonuclease I (NCBI) | conserved |
| b3811 | xerC | -1.2 | -1.1 | site-specific tyrosine recombinase XerC (NCBI) | compare |
| b3032 | cpdA | -1.1 | -6.5 | cyclic 3',5'-adenosine monophosphate phosphodiesterase (NCBI) | compare |
| b3149 | yraO | -1.1 | -6.3 | DnaA initiator-associating factor for replication initiation (NCBI) | compare |
| b3785 | wzzE | -1.1 | -7.6 | putative transport protein (VIMSS) | compare |
| b3625 | rfaY | -1.1 | -3.1 | lipopolysaccharide core biosynthesis protein (NCBI) | compare |
| b2822 | recC | -1.1 | -2.6 | exonuclease V (RecBCD complex), gamma chain (NCBI) | compare |
| b0683 | fur | -1.1 | -1.2 | ferric uptake regulator (NCBI) | compare |
| b4585 | sroB | -1.1 | -1.6 | Novel sRNA, function unknown (RefSeq) | compare |
| b0819 | ybiS | -1.1 | -5.5 | hypothetical protein (NCBI) | compare |
| b0547 | ybcN | -1.0 | -4.5 | DLP12 prophage; predicted protein (NCBI) | compare |
| b0890 | ftsK | -1.0 | -2.7 | DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) | compare |
| b0730 | mngR | -1.0 | -1.2 | DNA-binding transcriptional dual regulator, fatty-acyl-binding (NCBI) | compare |
| b2532 | yfhQ | -1.0 | -3.7 | predicted methyltransferase (NCBI) | compare |
| b3396 | mrcA | -1.0 | -9.1 | peptidoglycan synthetase; penicillin-binding protein 1A (VIMSS) | compare |
| b0946 | ycbW | -1.0 | -3.6 | orf, hypothetical protein (VIMSS) | compare |
| b3813 | uvrD | -1.0 | -6.4 | DNA-dependent ATPase I and helicase II (NCBI) | compare |
| b4203 | rplI | -1.0 | -3.8 | 50S ribosomal protein L9 (NCBI) | compare |
| b3794 | rffM | -1.0 | -5.3 | putative UDP-N-acetyl-D-mannosaminuronic acid transferase (NCBI) | compare |
| b3147 | yraM | -1.0 | -7.4 | hypothetical protein (NCBI) | compare |
| b4042 | dgkA | -1.0 | -1.8 | diacylglycerol kinase (NCBI) | compare |
| b1192 | ldcA | -1.0 | -4.6 | L,D-carboxypeptidase A (NCBI) | compare |
| b4480 | hdfR | -1.0 | -3.6 | transcriptional regulator HdfR (NCBI) | compare |
| b1130 | phoP | -1.0 | -0.6 | DNA-binding response regulator in two-component regulatory system with PhoQ (NCBI) | compare |
| b3617 | kbl | -1.0 | -5.1 | 2-amino-3-ketobutyrate coenzyme A ligase (NCBI) | compare |
| b3742 | mioC | -0.9 | -4.6 | flavodoxin (NCBI) | compare |
| b4062 | soxS | -0.9 | -3.8 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b1124 | potC | -0.9 | -4.2 | spermidine/putrescine ABC transporter membrane protein (NCBI) | compare |
| b1531 | marA | -0.9 | -2.8 | multiple antibiotic resistance; transcriptional activator of defense systems (VIMSS) | compare |
| b3726 | pstA | -0.9 | -3.9 | phosphate transporter subunit (NCBI) | compare |
| b2665 | ygaU | -0.9 | -4.5 | hypothetical protein (NCBI) | compare |
| b1712 | ihfA | -0.9 | -0.6 | integration host factor subunit alpha (NCBI) | compare |
| b3005 | exbD | -0.9 | -2.5 | membrane spanning protein in TonB-ExbB-ExbD complex (NCBI) | compare |
| b3017 | sufI | -0.9 | -6.8 | repressor protein for FtsI (NCBI) | compare |
| b2699 | recA | -0.9 | -0.6 | recombinase A (NCBI) | compare |
| b1273 | yciN | -0.9 | -1.6 | hypothetical protein (NCBI) | compare |
| b4535 | yniD | -0.9 | -1.1 | predicted protein (RefSeq) | compare |
| b3237 | argR | -0.9 | -3.7 | arginine repressor (NCBI) | compare |
| b1126 | potA | -0.9 | -3.7 | putrescine/spermidine ABC transporter ATPase protein (NCBI) | compare |
| b2820 | recB | -0.9 | -0.6 | exonuclease V (RecBCD complex), beta subunit (NCBI) | compare |
| b1658 | purR | -0.9 | -3.8 | DNA-binding transcriptional repressor, hypoxanthine-binding (NCBI) | compare |
| b2366 | dsdA | -0.9 | -3.2 | D-serine dehydratase (NCBI) | compare |
| b3404 | envZ | -0.9 | -6.0 | osmolarity sensor protein (NCBI) | compare |
| b4547 | ypfN | -0.8 | -2.9 | hypothetical protein (NCBI) | compare |
| b4048 | yjbM | -0.8 | -0.8 | hypothetical protein (NCBI) | compare |
| b0998 | torD | -0.8 | -1.0 | chaperone protein TorD (NCBI) | compare |
| b0814 | ompX | -0.8 | -3.1 | outer membrane protein X (NCBI) | compare |
| b3616 | tdh | -0.8 | -4.3 | L-threonine 3-dehydrogenase (NCBI) | compare |
| b1269 | rluB | -0.8 | -3.2 | 23S rRNA pseudouridylate synthase (NCBI) | compare |
| b1123 | potD | -0.8 | -3.9 | spermidine/putrescine ABC transporter periplasmic substrate-binding protein (NCBI) | compare |
| b0564 | appY | -0.8 | -0.7 | DLP12 prophage; DNA-binding transcriptional activator (NCBI) | compare |
| b1545 | pinQ | -0.8 | -0.3 | Qin prophage; predicted site-specific recombinase (NCBI) | compare |
| b2398 | yfeC | -0.8 | -3.4 | orf, hypothetical protein (VIMSS) | compare |
| b2325 | yfcL | -0.8 | -2.4 | hypothetical protein (NCBI) | compare |
| b3933 | ftsN | -0.8 | -4.3 | essential cell division protein (NCBI) | compare |
| b3728 | pstS | -0.8 | -1.8 | phosphate transporter subunit (NCBI) | compare |
| b1693 | aroD | -0.8 | -4.0 | 3-dehydroquinate dehydratase (NCBI) | compare |
| b3207 | yrbL | -0.8 | -4.6 | hypothetical protein (NCBI) | compare |
| b2893 | dsbC | -0.8 | -4.4 | protein disulfide isomerase II (NCBI) | compare |
| b3206 | npr | -0.8 | -2.7 | phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr) (NCBI) | compare |
| b4436 | ryeC | -0.8 | -1.5 | Novel sRNA, function unknown; paralogous to the other QUAD sRNA genes unknown (RefSeq) | compare |
| b1822 | rrmA | -0.8 | -2.9 | 23S rRNA m1G745 methyltransferase (NCBI) | compare |
| b2910 | zapA | -0.8 | -4.0 | protein that localizes to the cytokinetic ring (NCBI) | compare |
| b3119 | tdcR | -0.8 | -1.2 | threonine dehydratase operon activator protein (VIMSS) | compare |
| b2314 | dedD | -0.8 | -3.0 | putative lipoprotein (VIMSS) | compare |
| b0001 | thrL | -0.8 | -1.9 | thr operon leader peptide (NCBI) | compare |
| b0611 | rna | -0.8 | -3.7 | ribonuclease I (NCBI) | compare |
| b3687 | ibpA | -0.8 | -4.7 | heat shock chaperone (NCBI) | compare |
| b0590 | fepD | -0.7 | -4.7 | iron-enterobactin transporter subunit (NCBI) | compare |
| b0605 | ahpC | -0.7 | -2.3 | alkyl hydroperoxide reductase, C22 subunit (NCBI) | compare |
| b0143 | pcnB | -0.7 | -3.8 | poly(A) polymerase I (VIMSS) | compare |
| b4396 | rob | -0.7 | -5.2 | DNA-binding transcriptional activator (NCBI) | compare |
| b2637 | yfjT | -0.7 | -2.4 | CP4-57 prophage; predicted protein (NCBI) | compare |
| b0471 | ybaB | -0.7 | -1.9 | hypothetical protein (NCBI) | compare |
| b2894 | xerD | -0.7 | -0.9 | site-specific tyrosine recombinase XerD (NCBI) | compare |
| b3197 | kdsD | -0.7 | -3.4 | D-arabinose 5-phosphate isomerase (NCBI) | compare |
| b3391 | hofQ | -0.7 | -5.3 | predicted fimbrial transporter (NCBI) | compare |
| b2685 | emrA | -0.7 | -4.2 | multidrug efflux system (NCBI) | compare |
| b3229 | sspA | -0.7 | -1.8 | stringent starvation protein A (NCBI) | compare |
| b3096 | yqjB | -0.7 | -3.2 | hypothetical protein (NCBI) | compare |
| b3392 | yrfA | -0.7 | -3.7 | orf, hypothetical protein (VIMSS) | compare |
| b0763 | modA | -0.7 | -3.7 | molybdate transporter subunit (NCBI) | compare |
| b3363 | ppiA | -0.7 | -4.2 | peptidyl-prolyl cis-trans isomerase A (rotamase A) (NCBI) | compare |
| b4163 | glyV | -0.7 | -1.2 | tRNA-Gly (NCBI) | compare |
| b3932 | hslV | -0.7 | -5.2 | ATP-dependent protease peptidase subunit (NCBI) | compare |
| b0560 | nohB | -0.7 | -1.1 | DLP12 prophage; DNA packaging protein (NCBI) | compare |
| b2686 | emrB | -0.7 | -4.3 | multidrug efflux system protein (NCBI) | compare |
| b1558 | cspF | -0.7 | -1.5 | Qin prophage; cold shock protein (NCBI) | compare |
| b1954 | dsrA | -0.7 | -1.9 | regulatory antisense RNA (NCBI) | compare |
| b2819 | recD | -0.7 | -4.0 | exonuclease V (RecBCD complex), alpha chain (NCBI) | compare |
| b1090 | plsX | -0.7 | -3.6 | glycerolphosphate auxotrophy in plsB background (VIMSS) | compare |
| b3931 | hslU | -0.7 | -5.3 | ATP-dependent protease ATP-binding subunit (NCBI) | compare |
| b4389 | radA | -0.7 | -4.3 | predicted repair protein (NCBI) | compare |
| b3649 | rpoZ | -0.7 | -2.2 | DNA-directed RNA polymerase subunit omega (NCBI) | compare |
| b3021 | ygiT | -0.7 | -1.9 | predicted DNA-binding transcriptional regulator (NCBI) | compare |
| b1648 | b1648 | -0.7 | -1.2 | orf, hypothetical protein (VIMSS) | compare |
| b1286 | rnb | -0.7 | -1.6 | exoribonuclease II (NCBI) | compare |
| b0949 | uup | -0.7 | -4.1 | fused predicted transporter subunits of ABC superfamily: ATP-binding components (NCBI) | compare |
| b0959 | yccR | -0.6 | -2.5 | hypothetical protein (NCBI) | compare |
| b0989 | cspH | -0.6 | -1.4 | stress protein, member of the CspA-family (NCBI) | compare |
| b4220 | ytfM | -0.6 | -5.3 | predicted outer membrane protein and surface antigen (NCBI) | compare |
| b0577 | ybdG | -0.6 | -5.6 | predicted mechanosensitive channel (NCBI) | compare |
| b1194 | ycgR | -0.6 | -2.5 | protein involved in flagellar function (NCBI) | compare |