Experiment set12IT058 for Pseudomonas putida KT2440

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L-Glutamic acid monopotassium salt monohydrate carbon source

200 most detrimental genes:

  gene name fitness t score description  
PP_1650 +3.0 28.7 Sensor protein GacS compare
PP_4099 +2.9 27.6 two-componenent system BarA/UvrY - regulatory subunit compare
PP_1655 +2.1 11.8 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD compare
PP_4171 +2.0 15.0 conserved exported protein of unknown function compare
PP_1656 +1.3 6.8 ATP:GTP 3'-pyrophosphotransferase compare
PP_4902 +1.2 3.7 Oligoribonuclease compare
PP_4172 +1.2 7.1 conserved exported protein of unknown function compare
PP_5053 +1.1 5.1 Protein-export protein SecB compare
PP_4133 +1.1 2.6 Transcriptional regulator-related protein compare
PP_1113 +1.1 8.2 Pyridoxal-phosphate dependent enzyme family protein compare
PP_0232 +1.0 2.2 ATP-binding taurine transporter subunit compare
PP_4710 +0.9 7.0 tRNA pseudouridine 55 synthase compare
PP_5706 +0.9 2.2 Sec translocation complex - SecG subunit compare
PP_5017 +0.9 2.1 Sec-independent protein translocase protein TatB compare
PP_5508 +0.9 1.9 conserved protein of unknown function compare
PP_2889 +0.9 5.7 putative Transmembrane regulator PrtR compare
PP_3241 +0.9 1.8 conserved exported protein of unknown function compare
PP_1898 +0.8 3.0 MotA/TolQ/ExbB proton channel family protein compare
PP_1186 +0.8 1.0 two component system DNA-binding transcriptional dual regulator compare
PP_5475 +0.8 2.6 conserved protein of unknown function compare
PP_2231 +0.8 2.4 putative permease of the drug/metabolite transporter (DMT) superfamily compare
PP_1702 +0.8 2.9 Recombination-associated protein RdgC compare
PP_1215 +0.8 1.2 Crossover junction endodeoxyribonuclease RuvC compare
PP_4227 +0.8 2.5 conserved protein of unknown function compare
PP_2650 +0.8 3.3 putative 4-hydroxybutyrate dehydrogenase compare
PP_3938 +0.8 1.9 conserved protein of unknown function compare
PP_0674 +0.7 6.2 ADP/ATP ratio sensor and inhibitor of translation compare
PP_2387 +0.7 3.1 conserved protein of unknown function compare
PP_4835 +0.7 1.4 conserved exported protein of unknown function compare
PP_2189 +0.7 2.6 conserved protein of unknown function compare
PP_3880 +0.7 1.8 conserved exported protein of unknown function compare
PP_4173 +0.7 3.8 Sensor histidine kinase/response regulator compare
PP_0685 +0.7 2.6 conserved protein of unknown function compare
PP_5610 +0.7 2.2 protein of unknown function compare
PP_1683 +0.7 1.8 Transcriptional regulator, MarR family compare
PP_4247 +0.7 1.8 Exonuclease compare
PP_4213 +0.6 2.0 putative dipeptidase compare
PP_2530 +0.6 2.5 conserved protein of unknown function compare
PP_4136 +0.6 1.4 Transcriptional regulator, LuxR family compare
PP_0414 +0.6 3.3 Polyamine ABC transporter, permease protein compare
PP_2681 +0.6 1.7 coenzyme PQQ synthesis protein D compare
PP_5248 +0.6 1.2 putative hydrolase compare
PP_4797 +0.6 1.6 conserved protein of unknown function compare
PP_5619 +0.6 1.8 protein of unknown function compare
PP_2306 +0.6 2.0 conserved exported protein of unknown function compare
PP_1623 +0.6 4.4 RNA polymerase, sigma S (sigma 38) factor compare
PP_4994 +0.6 2.1 conserved protein of unknown function compare
PP_4528 +0.6 1.7 conserved protein of unknown function compare
PP_1313 +0.6 4.5 Transcriptional regulator, AraC family compare
PP_2748 +0.6 1.7 putative Branched-chain amino acid ABC transporter, ATP-binding protein compare
PP_1112 +0.6 4.1 conserved membrane protein of unknown function compare
PP_3541 +0.6 2.5 Transporter, MgtC family compare
PP_5090 +0.6 1.6 putative cell division protein compare
PP_3460 +0.6 1.6 quinohemoprotein amine dehydrogenase, gamma subunit compare
PP_2340 +0.6 1.7 conserved protein of unknown function compare
PP_4217 +0.6 5.3 outer membrane ferripyoverdine receptor FpvA, TonB-dependent compare
PP_4273 +0.6 0.8 Transcriptional regulator, MerR family compare
PP_1293 +0.6 1.1 molybdopterin synthase small subunit compare
PP_0958 +0.6 2.7 phospholipid ABC transporter ATP-binding subunit compare
PP_1225 +0.5 2.5 7-carboxy-7-deazaguanine synthase compare
PP_2653 +0.5 1.6 Transcriptional regulator, Cro/CI family compare
PP_5073 +0.5 1.4 conserved exported protein of unknown function compare
PP_4929 +0.5 2.4 Transcriptional regulator, LysR family compare
PP_1562 +0.5 1.1 putative Phage terminase, small subunit compare
PP_3831 +0.5 2.7 conserved protein of unknown function compare
PP_1353 +0.5 0.8 conserved membrane protein of unknown function compare
PP_4642 +0.5 1.0 Cyclic diguanosine monophosphate-binding protein compare
PP_4499 +0.5 1.8 putative maturation enzyme compare
PP_4532 +0.5 1.2 ATP-dependent DEAD-box RNA helicase require for 50S ribosomal subunit biogenesis compare
PP_0770 +0.5 2.5 PemI-like protein compare
PP_0819 +0.5 1.9 conserved ferredoxin-like protein of unknown function compare
PP_0859 +0.5 2.4 putative ketoglutaramate omega-amidase compare
PP_2160 +0.5 1.7 NADPH-dependent 7-cyano-7-deazaguanine reductase compare
PP_5253 +0.5 1.6 Arylesterase compare
PP_5439 +0.5 2.4 conserved protein of unknown function compare
PP_1176 +0.5 0.9 conserved protein of unknown function compare
PP_3779 +0.5 3.5 Transcriptional regulator, LysR family compare
PP_5177 +0.5 2.6 spermidine/putrescine ABC transporter - permease subunit compare
PP_2760 +0.5 3.0 putative ribose transport permease protein compare
PP_4787 +0.5 1.3 putative protein with nucleoside triphosphate hydrolase domain compare
PP_0804 +0.5 3.0 Protein secretion ABC efflux system, permease and ATP-binding protein compare
PP_3058 +0.5 2.4 conserved protein of unknown function compare
PP_0703 +0.5 2.3 putative Transmembrane sensor compare
PP_0663 +0.5 2.7 Transcriptional regulator, AsnC family compare
PP_0805 +0.5 3.6 Outer membrane efflux protein compare
PP_3782 +0.5 2.3 conserved protein of unknown function compare
PP_4910 +0.5 0.9 conserved protein of unknown function compare
PP_1633 +0.5 1.5 conserved exported protein of unknown function compare
PP_2684 +0.5 1.6 conserved membrane protein of unknown function compare
PP_2060 +0.5 1.2 DNA-binding transcriptional dual regulator - SoxR-reversible one-electron oxidation of its [2Fe-2S] cluster, NADPH-dependent compare
PP_2083 +0.5 1.9 putative Lipase compare
PP_0961 +0.5 2.7 toluene tolerance protein compare
PP_1776 +0.5 4.2 Mannose-6-phosphate isomerase/mannose-1-phosphate guanylyltransferase compare
PP_1307 +0.5 2.1 AsnC family transcriptional regulator compare
PP_0250 +0.4 1.6 heat shock protein Hsp15 involved in ribosome recycling compare
PP_3691 +0.4 4.3 DNA helicase-related protein compare
PP_1404 +0.4 1.6 conserved protein of unknown function compare
PP_3522 +0.4 1.1 conserved protein of unknown function compare
PP_3732 +0.4 2.3 Enoyl-CoA hydratase/isomerase family protein compare
PP_2210 +0.4 2.0 LysR family transcriptional regulator compare
PP_1892 +0.4 1.5 conserved protein of unknown function compare
PP_4262 +0.4 1.2 Cytochrome oxidase maturation protein, cbb3-type compare
PP_2090 +0.4 1.6 Uroporphyrinogen-III C-methyltransferase compare
PP_2054 +0.4 2.1 putative DNA-binding transcriptional regulator compare
PP_4180 +0.4 2.0 conserved protein of unknown function compare
PP_4561 +0.4 0.5 stress response protein compare
PP_3257 +0.4 2.4 putative Methyltransferase compare
PP_2044 +0.4 1.1 conserved inner membrane protein of unknown function compare
PP_0607 +0.4 1.9 putative Type IV pili biogenesis protein FimT compare
PP_5225 +0.4 0.7 frataxin compare
PP_4311 +0.4 2.2 putative D-amino acid dehydrogenase 2 small subunit compare
PP_5354 +0.4 2.6 conserved protein of unknown function compare
PP_4980 +0.4 2.3 ATP-dependent RNA helicase compare
PP_1187 +0.4 2.0 sensor protein compare
PP_0416 +0.4 2.7 Phosphoglycolate phosphatase compare
PP_1903 +0.4 1.1 putative phosphotyrosine-protein phosphatase compare
PP_0276 +0.4 0.8 Transcriptional regulator, Cro/CI family compare
PP_3614 +0.4 1.3 conserved membrane protein of unknown function compare
PP_0238 +0.4 2.0 alkanesulfonate monooxygenase compare
PP_0565 +0.4 1.1 putative enzyme compare
PP_0092 +0.4 1.9 putative lipoprotein compare
PP_2759 +0.4 1.7 ribose ABC transporter - ATP-binding subunit compare
PP_4373 +0.4 3.3 Transcriptional regulator FleQ compare
PP_5582 +0.4 0.9 conserved protein of unknown function compare
PP_0326 +0.4 1.7 sarcosine oxidase subunit gamma compare
PP_1141 +0.4 2.6 branched-chain amino acids ABC transporter - periplasmic leucine binding subunit compare
PP_2860 +0.4 2.1 putative Nicotinamide mononucleotide transporter compare
PP_3509 +0.4 2.0 Glyoxalase family protein compare
PP_5600 +0.4 1.8 conserved protein of unknown function compare
PP_2148 +0.4 2.9 transcription-repair coupling factor compare
PP_4846 +0.4 1.7 L-amino acid N-acyltransferase compare
PP_4100 +0.4 1.7 Transcriptional regulator, Cro/CI family compare
PP_3160 +0.4 2.9 conserved protein of unknown function compare
PP_1817 +0.4 2.0 Oxidoreductase, short-chain dehydrogenase/reductase family compare
PP_0719 +0.4 0.2 ribosome-associated potassium-dependent informational ATP/GTPase compare
PP_2140 +0.4 1.4 conserved protein of unknown function compare
PP_2950 +0.4 1.5 conserved protein of unknown function compare
PP_3903 +0.4 1.1 conserved protein of unknown function compare
PP_0806 +0.4 3.6 putative Surface adhesion protein compare
PP_3089 +0.4 1.6 conserved protein of unknown function compare
PP_3524 +0.4 2.4 conserved protein of unknown function compare
PP_2437 +0.4 2.9 putative Acyl-CoA dehydrogenase compare
PP_0803 +0.4 2.8 Protein secretion ABC efflux system, membrane fusion protein compare
PP_2514 +0.4 2.1 4-carboxy-4-hydroxy-2-oxoadipic acid aldolase compare
PP_0973 +0.4 1.8 Nucleoid-associated protein PP_0973 compare
PP_4985 +0.4 1.6 16S rRNA m3U1498 methyltransferase compare
PP_4961 +0.4 0.9 putative Lipoprotein compare
PP_2147 +0.4 2.1 conserved exported protein of unknown function compare
PP_2207 +0.4 1.5 conserved membrane protein of unknown function compare
PP_4073 +0.4 0.8 conserved exported protein of unknown function compare
PP_3467 +0.4 1.8 Sigma-54 dependent transcriptional regulator compare
PP_5000 +0.4 0.5 peptidase component of the ATP-dependent HslVU protease compare
PP_1095 +0.4 2.0 putative electron transport complex protein compare
PP_5064 +0.4 2.3 choline dehydrogenase compare
PP_1051 +0.4 1.5 Type II secretion pathway protein XcpV compare
PP_5339 +0.4 1.6 transcriptional regulator, ornithine utilization compare
PP_2109 +0.4 2.5 conserved protein of unknown function compare
PP_0999 +0.4 2.3 carbamate kinase compare
PP_3245 +0.4 1.1 conserved protein of unknown function compare
PP_3318 +0.4 0.6 conserved protein of unknown function compare
PP_5148 +0.4 1.8 conserved membrane protein of unknown function compare
PP_4067 +0.4 2.0 methylcrotonyl-CoA carboxylase biotin-containing subunit alpha compare
PP_0643 +0.4 1.0 protein of unknown function compare
PP_5441 +0.4 1.4 protein of unknown function compare
PP_5313 +0.4 0.8 DNA-binding protein HU-alpha compare
PP_0694 +0.4 1.3 conserved protein of unknown function compare
PP_2677 +0.4 1.1 conserved exported protein of unknown function compare
PP_3715 +0.4 1.3 Muconate cycloisomerase 1 compare
PP_5027 +0.4 0.7 D-tyrosyl-tRNA(Tyr) deacylase compare
PP_3401 +0.4 1.5 conserved protein of unknown function compare
PP_0809 +0.3 2.5 disulfide bond formation protein B compare
PP_0633 +0.3 1.5 Type 4 fimbrial assembly protein PilC compare
PP_1236 +0.3 1.7 putative Glycine cleavage system transcriptional repressor compare
PP_2409 +0.3 1.1 cobalt-zinc-cadmium resistance protein compare
PP_2814 +0.3 2.0 conserved protein of unknown function compare
PP_1739 +0.3 1.6 conserved membrane protein of unknown function compare
PP_1722 +0.3 2.0 ABC transporter, ATP-binding protein compare
PP_0087 +0.3 1.6 conserved exported protein of unknown function compare
PP_4484 +0.3 2.7 histidine / lysine / arginine / ornithine ABC transporter - permease subunit compare
PP_3314 +0.3 1.6 Heat shock protein, HSP20 family compare
PP_2309 +0.3 0.7 conserved protein of unknown function compare
PP_2313 +0.3 1.1 conserved membrane protein of unknown function compare
PP_1494 +0.3 2.0 Response regulator/GGDEF domain protein compare
PP_0886 +0.3 1.1 conserved exported protein of unknown function compare
PP_4947 +0.3 2.9 proline dehydrogenase/1-pyrroline-5-carboxylate dehydrogenase compare
PP_4483 +0.3 1.9 histidine lysine / arginine / ornithine ABC transporter - ATP binding subunit compare
PP_0976 +0.3 2.0 Ribosomal RNA large subunit methyltransferase F compare
PP_5670 +0.3 1.8 conserved protein of unknown function compare
PP_4692 +0.3 2.4 putative aspartate/tyrosine/aromatic aminotransferase compare
PP_0261 +0.3 1.8 adenosine-3'(2'),5'-bisphosphate nucleotidase compare
PP_2225 +0.3 2.1 putative Multicomponent potassium-proton antiporter, subunit G compare
PP_1584 +0.3 1.7 conserved protein of unknown function compare
PP_4296 +0.3 0.6 conserved exported protein of unknown function compare
PP_3940 +0.3 1.7 Putative metabolite transport protein NicT compare
PP_4981 +0.3 1.0 polyisoprene-binding protein, acidic stress response factor compare
PP_4946 +0.3 2.3 sodium/L-proline transporter compare
PP_3823 +0.3 1.5 Cytochrome c-type protein compare
PP_2937 +0.3 1.9 putative Integrase compare
PP_3942 +0.3 1.8 maleate isomerase compare
PP_2540 +0.3 1.0 Oxidoreductase, short-chain dehydrogenase/reductase family compare


Specific Phenotypes

For 12 genes in this experiment

For carbon source L-Glutamic acid monopotassium salt monohydrate in Pseudomonas putida KT2440

For carbon source L-Glutamic acid monopotassium salt monohydrate across organisms