Experiment set12IT047 for Pseudomonas putida KT2440

Compare to:

Protocatechuic Acid carbon source

200 most detrimental genes:

  gene name fitness t score description  
PP_1650 +3.3 29.0 Sensor protein GacS compare
PP_4099 +3.2 31.1 two-componenent system BarA/UvrY - regulatory subunit compare
PP_4171 +2.4 14.5 conserved exported protein of unknown function compare
PP_4373 +1.6 12.6 Transcriptional regulator FleQ compare
PP_5053 +1.5 6.2 Protein-export protein SecB compare
PP_3938 +1.4 2.9 conserved protein of unknown function compare
PP_2889 +1.3 5.2 putative Transmembrane regulator PrtR compare
PP_1623 +1.2 9.2 RNA polymerase, sigma S (sigma 38) factor compare
PP_2387 +1.2 3.3 conserved protein of unknown function compare
PP_0566 +1.2 2.0 translation-related factor compare
PP_3726 +1.2 3.2 Enoyl-CoA hydratase/isomerase family protein compare
PP_4173 +1.1 5.7 Sensor histidine kinase/response regulator compare
PP_4172 +1.1 6.1 conserved exported protein of unknown function compare
PP_0959 +1.0 1.9 phospholipid ABC transporter compare
PP_3761 +1.0 8.1 Sensor histidine kinase/response regulator compare
PP_3392 +1.0 3.2 conserved protein of unknown function compare
PP_5232 +1.0 2.5 conserved protein of unknown function compare
PP_1898 +1.0 3.1 MotA/TolQ/ExbB proton channel family protein compare
PP_2631 +0.9 2.5 putative cellulose biosynthesis, BcsF/YhjT compare
PP_4959 +0.9 6.1 diguanylate cyclase compare
PP_1528 +0.9 2.1 conserved protein of unknown function compare
PP_1663 +0.9 6.2 conserved exported protein of unknown function compare
PP_2857 +0.9 1.6 conserved exported protein of unknown function compare
PP_3831 +0.9 2.9 conserved protein of unknown function compare
PP_2107 +0.9 1.6 conserved protein of unknown function compare
PP_0574 +0.9 6.9 DNA-binding response regulator, LuxR family compare
PP_4217 +0.8 7.8 outer membrane ferripyoverdine receptor FpvA, TonB-dependent compare
PP_0960 +0.8 3.2 phospholipid ABC transporter binding protein compare
PP_3258 +0.8 2.9 conserved protein of unknown function compare
PP_4262 +0.8 1.8 Cytochrome oxidase maturation protein, cbb3-type compare
PP_2581 +0.8 2.5 conserved protein of unknown function compare
PP_3527 +0.8 5.9 Transcriptional regulator, TetR family compare
PP_4363 +0.8 6.3 Sensor histidine kinase/response regulator compare
PP_4482 +0.8 2.7 Transcriptional regulator, AraC family compare
PP_1113 +0.8 5.9 Pyridoxal-phosphate dependent enzyme family protein compare
PP_1041 +0.8 2.4 twin arginine protein export complex subunit compare
PP_0962 +0.8 2.5 toluene-tolerance protein compare
PP_4994 +0.8 3.3 conserved protein of unknown function compare
PP_4738 +0.7 3.2 conserved exported protein of unknown function compare
PP_5582 +0.7 1.6 conserved protein of unknown function compare
PP_2653 +0.7 2.8 Transcriptional regulator, Cro/CI family compare
PP_0961 +0.7 4.0 toluene tolerance protein compare
PP_0672 +0.7 6.2 Sensory box protein compare
PP_0958 +0.7 3.7 phospholipid ABC transporter ATP-binding subunit compare
PP_5610 +0.7 2.2 protein of unknown function compare
PP_1038 +0.7 2.4 conserved protein of unknown function compare
PP_4100 +0.7 2.9 Transcriptional regulator, Cro/CI family compare
PP_2712 +0.7 3.1 conserved exported protein of unknown function compare
PP_0683 +0.7 1.7 conserved protein of unknown function compare
PP_3738 +0.7 2.0 putative Transcriptional regulator VanR compare
PP_1237 +0.7 1.2 4-hydroxy-tetrahydrodipicolinate synthase compare
PP_5441 +0.7 1.4 protein of unknown function compare
PP_4966 +0.7 1.3 transcriptional regulator of methionine metabolism compare
PP_0674 +0.7 5.5 ADP/ATP ratio sensor and inhibitor of translation compare
PP_3398 +0.7 1.3 putative Curli fiber surface-exposed nucleator CsgB compare
PP_5557 +0.7 2.4 protein of unknown function compare
PP_2163 +0.6 3.5 VacJ lipoprotein compare
PP_0874 +0.6 1.4 conserved protein of unknown function compare
PP_0003 +0.6 1.5 16S RNA methyltransferase compare
PP_0185 +0.6 4.1 Positive alginate biosynthesis regulatory protein compare
PP_3808 +0.6 1.6 Antibiotic synthesis protein MbtH compare
PP_4757 +0.6 3.5 D-glucarate dehydratase / L-idarate epimerase compare
PP_2413 +0.6 4.7 GGDEF family protein compare
PP_0355 +0.6 1.7 Response regulator compare
PP_1324 +0.6 2.7 putative endonuclease distantly related to archaeal Holliday junction resolvase compare
PP_2633 +0.6 1.7 conserved protein of unknown function compare
PP_2950 +0.6 2.3 conserved protein of unknown function compare
PP_5267 +0.6 0.9 putative cytochrome c5 compare
PP_4328 +0.6 2.1 conserved protein of unknown function compare
PP_0414 +0.6 2.6 Polyamine ABC transporter, permease protein compare
PP_0274 +0.6 1.2 putative transcriptional regulator containing HTH domain compare
PP_1112 +0.6 3.7 conserved membrane protein of unknown function compare
PP_4720 +0.6 1.6 putative RNA binding protein compare
PP_2231 +0.6 1.6 putative permease of the drug/metabolite transporter (DMT) superfamily compare
PP_5748 +0.6 2.0 cytochrome c heme lyase subunit compare
PP_4532 +0.6 1.2 ATP-dependent DEAD-box RNA helicase require for 50S ribosomal subunit biogenesis compare
PP_1692 +0.6 1.4 conserved protein of unknown function compare
PP_5619 +0.6 2.8 protein of unknown function compare
PP_1655 +0.6 2.6 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD compare
PP_2256 +0.6 2.6 Transcriptional regulator, Cro/CI family compare
PP_2257 +0.6 3.1 putative aerotaxis receptor compare
PP_0063 +0.6 1.3 putative Lipid A biosynthesis lauroyl acyltransferase compare
PP_0173 +0.6 3.0 putative transcriptional factor-related protein compare
PP_3757 +0.6 1.3 Chemotaxis protein CheY compare
PP_4268 +0.5 0.7 nucleoid-associated broad specificity regulator compare
PP_3346 +0.5 2.4 Nickel transporter ATP-binding protein compare
PP_5317 +0.5 1.2 Probable chorismate pyruvate-lyase compare
PP_0806 +0.5 5.1 putative Surface adhesion protein compare
PP_0948 +0.5 1.8 Phosphocarrier protein HPr compare
PP_5017 +0.5 1.0 Sec-independent protein translocase protein TatB compare
PP_5572 +0.5 1.3 protein of unknown function compare
PP_0738 +0.5 1.5 conserved protein of unknown function compare
PP_5448 +0.5 1.9 conserved protein of unknown function compare
PP_0092 +0.5 1.9 putative lipoprotein compare
PP_4662 +0.5 1.8 conserved protein of unknown function compare
PP_2510 +0.5 1.1 conserved protein of unknown function compare
PP_1258 +0.5 2.3 4-hydroxyproline epimerase compare
PP_2217 +0.5 1.1 enoyl-CoA hydratase compare
PP_0585 +0.5 2.2 putative metal-sensitive transcriptional regulator, MerR family compare
PP_0973 +0.5 2.5 Nucleoid-associated protein PP_0973 compare
PP_4997 +0.5 1.3 pyrimidine operon regulatory protein/uracil phosphoribosyltransferase compare
PP_2923 +0.5 1.9 conserved protein of unknown function compare
PP_5332 +0.5 3.1 conserved protein of unknown function compare
PP_4427 +0.5 2.9 Amino acid ABC transporter, permease protein compare
PP_1141 +0.5 2.8 branched-chain amino acids ABC transporter - periplasmic leucine binding subunit compare
PP_0352 +0.5 1.9 RNA polymerase sigma-70 factor, ECF subfamily compare
PP_5471 +0.5 0.5 putative response regulator receiver protein compare
PP_2222 +0.5 1.4 conserved protein of unknown function compare
PP_1208 +0.5 0.8 conserved protein of unknown function, SlyX family compare
PP_2457 +0.5 3.5 DNA-binding transcriptional repressor compare
PP_2809 +0.5 1.7 conserved membrane protein of unknown function compare
PP_1529 +0.5 2.1 Probable cysteine desulfurase compare
PP_4419 +0.5 1.3 transposase compare
PP_4102 +0.5 2.1 conserved protein of unknown function compare
PP_0719 +0.5 0.2 ribosome-associated potassium-dependent informational ATP/GTPase compare
PP_3919 +0.5 2.0 conserved protein of unknown function compare
PP_3989 +0.5 1.1 DNA-cytosine methyltransferase compare
PP_2756 +0.5 2.2 conserved protein of unknown function compare
PP_1140 +0.5 4.0 branched chain amino acid transporter - permease subunit compare
PP_5248 +0.5 1.2 putative hydrolase compare
PP_5654 +0.5 1.5 putative phosphotriesterase compare
PP_2677 +0.5 1.5 conserved exported protein of unknown function compare
PP_5225 +0.5 0.8 frataxin compare
PP_2455 +0.5 3.2 ribose ABC transporter - ATP-binding subunit compare
PP_5093 +0.5 0.7 twitching motility protein compare
PP_1428 +0.5 0.7 Sigma factor AlgU negative regulatory protein compare
PP_1562 +0.5 1.5 putative Phage terminase, small subunit compare
PP_3401 +0.5 2.1 conserved protein of unknown function compare
PP_3748 +0.5 2.1 conserved hypothetical protein compare
PP_1385 +0.5 3.7 Probable efflux pump membrane transporter TtgB compare
PP_5054 +0.5 0.8 glutaredoxin 3 compare
PP_2866 +0.5 3.1 FMN-dependent NADH-azoreductase 1 compare
PP_3237 +0.5 2.3 Universal stress protein family compare
PP_0007 +0.5 1.1 conserved hypothetical protein compare
PP_3056 +0.5 1.8 putative Pyocin R2_PP, tail fiber protein compare
PP_2127 +0.5 2.3 Sensor histidine kinase compare
PP_2054 +0.5 1.1 putative DNA-binding transcriptional regulator compare
PP_5705 +0.4 0.8 protein of unknown function compare
PP_3006 +0.4 2.6 RNA polymerase sigma-70 factor, ECF subfamily compare
PP_4273 +0.4 0.7 Transcriptional regulator, MerR family compare
PP_4227 +0.4 0.9 conserved protein of unknown function compare
PP_1325 +0.4 2.1 putative lipoprotein compare
PP_3765 +0.4 2.0 H-NS family protein MvaT compare
PP_3908 +0.4 1.6 conserved protein of unknown function compare
PP_0805 +0.4 2.9 Outer membrane efflux protein compare
PP_1656 +0.4 2.5 ATP:GTP 3'-pyrophosphotransferase compare
PP_0232 +0.4 0.7 ATP-binding taurine transporter subunit compare
PP_4778 +0.4 1.9 23S rRNA pseudouridine 2457 synthase compare
PP_1575 +0.4 0.8 conserved protein of unknown function compare
PP_4722 +0.4 1.7 Transcription elongation factor GreA compare
PP_0803 +0.4 3.1 Protein secretion ABC efflux system, membrane fusion protein compare
PP_2773 +0.4 1.0 conserved protein of unknown function compare
PP_5541 +0.4 2.0 conserved protein of unknown function compare
PP_0923 +0.4 2.7 Acyltransferase compare
PP_3353 +0.4 1.8 putative sulfatase-modifying factor (C-alpha-formyglycine- generating enzyme) compare
PP_2860 +0.4 2.5 putative Nicotinamide mononucleotide transporter compare
PP_4265 +0.4 1.2 DNA-binding transcriptional dual regulator compare
PP_5084 +0.4 2.7 penicillin-insensitive transglycosylase/penicillin-sensitive transpeptidase compare
PP_1344 +0.4 1.0 conserved protein of unknown function compare
PP_1439 +0.4 1.2 conserved exported protein of unknown function compare
PP_3265 +0.4 1.2 putative phosphohydrolase of unknown function compare
PP_2174 +0.4 2.2 conserved protein of unknown function compare
PP_1644 +0.4 2.1 NAD(P)H dehydrogenase (quinone) compare
PP_2341 +0.4 0.8 6-carboxy-5,6,7,8-tetrahydropterin synthase compare
PP_2976 +0.4 1.0 putative transposase compare
PP_1089 +0.4 2.3 conserved protein of unknown function compare
PP_1845 +0.4 1.1 Enoyl-CoA hydratase/isomerase family protein compare
PP_4929 +0.4 2.3 Transcriptional regulator, LysR family compare
PP_1001 +0.4 1.9 arginine deiminase compare
PP_1225 +0.4 1.4 7-carboxy-7-deazaguanine synthase compare
PP_0025 +0.4 0.8 hypothetical protein compare
PP_2349 +0.4 2.4 nitrite transporter, HPP family (from data) compare
PP_0957 +0.4 1.3 D-arabinose 5-phosphate isomerase compare
PP_0886 +0.4 1.5 conserved exported protein of unknown function compare
PP_2118 +0.4 1.2 conserved protein of unknown function compare
PP_4301 +0.4 1.4 Pyruvate kinase compare
PP_5309 +0.4 0.3 oxidative and nitrosative stress transcriptional dual regulator compare
PP_5561 +0.4 2.3 conserved protein of unknown function compare
PP_2046 +0.4 1.5 Transcriptional regulator, LysR family compare
PP_5571 +0.4 0.8 conserved protein of unknown function compare
PP_0287 +0.4 1.6 conserved exported protein of unknown function compare
PP_4223 +0.4 1.0 diaminobutyrate-2-oxoglutarate transaminase compare
PP_1651 +0.4 2.1 two-component response regulator compare
PP_2171 +0.4 1.2 Transporter, LysE family compare
PP_1627 +0.4 2.5 conserved protein of unknown function compare
PP_5429 +0.4 2.3 protein of unknown function compare
PP_2462 +0.4 1.6 conserved protein of unknown function compare
PP_1386 +0.4 2.2 Probable efflux pump periplasmic linker TtgA compare
PP_5489 +0.4 1.3 conserved protein of unknown function compare
PP_5139 +0.4 1.6 cadmium translocating P-type ATPase compare
PP_3314 +0.4 1.4 Heat shock protein, HSP20 family compare
PP_5103 +0.4 2.4 tRNA (guanine-N(7)-)-methyltransferase compare
PP_3899 +0.4 1.2 conserved protein of unknown function, hicB family compare
PP_0563 +0.4 2.9 Response regulator compare
PP_3469 +0.4 1.6 conserved protein of unknown function compare
PP_4811 +0.4 1.5 Gamma-glutamyl phosphate reductase compare
PP_2906 +0.4 2.4 Sensor histidine kinase compare
PP_4406 +0.4 1.0 conserved protein of unknown function compare
PP_0113 +0.4 1.5 methionine ABC transporter, permease protein compare
PP_4835 +0.4 1.5 conserved exported protein of unknown function compare


Specific Phenotypes

For 9 genes in this experiment

For carbon source Protocatechuic Acid in Pseudomonas putida KT2440

For carbon source Protocatechuic Acid across organisms