Experiment set12IT044 for Pseudomonas putida KT2440

Compare to:

Vanillic Acid carbon source

200 most detrimental genes:

  gene name fitness t score description  
PP_4171 +1.8 15.7 conserved exported protein of unknown function compare
PP_5053 +1.6 5.7 Protein-export protein SecB compare
PP_2387 +1.6 7.0 conserved protein of unknown function compare
PP_4994 +1.4 5.3 conserved protein of unknown function compare
PP_1650 +1.3 10.7 Sensor protein GacS compare
PP_1623 +1.3 8.9 RNA polymerase, sigma S (sigma 38) factor compare
PP_4099 +1.3 12.2 two-componenent system BarA/UvrY - regulatory subunit compare
PP_3739 +1.2 8.6 porin-like protein compare
PP_4173 +1.2 7.7 Sensor histidine kinase/response regulator compare
PP_1898 +1.2 3.8 MotA/TolQ/ExbB proton channel family protein compare
PP_5248 +1.1 2.7 putative hydrolase compare
PP_0948 +1.1 4.5 Phosphocarrier protein HPr compare
PP_3398 +1.1 2.0 putative Curli fiber surface-exposed nucleator CsgB compare
PP_2309 +1.0 2.5 conserved protein of unknown function compare
PP_3740 +0.9 7.0 Major facilitator family transporter compare
PP_5145 +0.9 8.7 phosphoenolpyruvate-dependent regulator (with NPR and NTR proteins) compare
PP_5000 +0.9 1.3 peptidase component of the ATP-dependent HslVU protease compare
PP_3938 +0.9 2.0 conserved protein of unknown function compare
PP_1113 +0.9 6.0 Pyridoxal-phosphate dependent enzyme family protein compare
PP_2889 +0.8 4.4 putative Transmembrane regulator PrtR compare
PP_2118 +0.8 1.4 conserved protein of unknown function compare
PP_1575 +0.8 2.0 conserved protein of unknown function compare
PP_4172 +0.8 4.2 conserved exported protein of unknown function compare
PP_5706 +0.8 1.3 Sec translocation complex - SecG subunit compare
PP_3757 +0.8 3.3 Chemotaxis protein CheY compare
PP_2923 +0.8 2.2 conserved protein of unknown function compare
PP_2341 +0.8 1.7 6-carboxy-5,6,7,8-tetrahydropterin synthase compare
PP_5652 +0.8 1.4 conserved protein of unknown function, phage origin compare
PP_2060 +0.8 1.9 DNA-binding transcriptional dual regulator - SoxR-reversible one-electron oxidation of its [2Fe-2S] cluster, NADPH-dependent compare
PP_3715 +0.8 2.6 Muconate cycloisomerase 1 compare
PP_5483 +0.7 1.4 conserved protein of unknown function compare
PP_3307 +0.7 2.5 conserved protein of unknown function compare
PP_2070 +0.7 2.2 Transcriptional regulator, AraC family compare
PP_2958 +0.7 3.2 Glutaredoxin compare
PP_0246 +0.7 2.0 two-component system DNA-binding response transcriptional dual regulator compare
PP_2222 +0.7 3.7 conserved protein of unknown function compare
PP_2661 +0.7 2.1 conserved protein of unknown function compare
PP_1404 +0.7 1.6 conserved protein of unknown function compare
PP_5054 +0.7 0.8 glutaredoxin 3 compare
PP_4213 +0.7 2.3 putative dipeptidase compare
PP_1226 +0.7 2.5 pre-queuosine 0 synthase compare
PP_1938 +0.7 2.2 conserved protein of unknown function compare
PP_5552 +0.7 2.2 conserved protein of unknown function compare
PP_1515 +0.7 2.8 Transcriptional regulator, tetR family compare
PP_3239 +0.7 1.8 putative cointegrate resolution protein T Tn4652 compare
PP_4262 +0.6 1.4 Cytochrome oxidase maturation protein, cbb3-type compare
PP_4785 +0.6 3.4 conserved exported protein of unknown function compare
PP_1692 +0.6 3.1 conserved protein of unknown function compare
PP_1112 +0.6 4.1 conserved membrane protein of unknown function compare
PP_4582 +0.6 3.0 conserved membrane protein of unknown function compare
PP_2970 +0.6 1.4 conserved exported protein of unknown function compare
PP_5331 +0.6 2.2 Long-chain acyl-CoA thioester hydrolase compare
PP_4073 +0.6 1.7 conserved exported protein of unknown function compare
PP_2462 +0.6 1.4 conserved protein of unknown function compare
PP_3580 +0.6 1.2 conserved protein of unknown function compare
PP_1683 +0.6 1.2 Transcriptional regulator, MarR family compare
PP_5475 +0.6 1.7 conserved protein of unknown function compare
PP_4180 +0.6 2.5 conserved protein of unknown function compare
PP_4797 +0.6 1.8 conserved protein of unknown function compare
PP_1697 +0.6 2.0 transcriptional regulator, GntR family compare
PP_4373 +0.6 4.0 Transcriptional regulator FleQ compare
PP_4966 +0.6 2.9 transcriptional regulator of methionine metabolism compare
PP_1663 +0.6 3.7 conserved exported protein of unknown function compare
PP_0163 +0.6 4.0 putative transcriptional regulator compare
PP_1386 +0.6 3.7 Probable efflux pump periplasmic linker TtgA compare
PP_1109 +0.6 4.7 Transcriptional regulator, GntR family compare
PP_1385 +0.6 4.4 Probable efflux pump membrane transporter TtgB compare
PP_3765 +0.5 1.9 H-NS family protein MvaT compare
PP_0287 +0.5 2.8 conserved exported protein of unknown function compare
PP_0959 +0.5 1.8 phospholipid ABC transporter compare
PP_1142 +0.5 1.0 conserved protein of unknown function compare
PP_3407 +0.5 1.5 conserved protein of unknown function compare
PP_1892 +0.5 1.4 conserved protein of unknown function compare
PP_3127 +0.5 2.9 putative Exopolysaccharide transport protein compare
PP_0258 +0.5 3.0 regulator of murein cross-linking compare
PP_4760 +0.5 2.3 Alcohol dehydrogenase, zinc-containing compare
PP_2765 +0.5 1.5 putative Sulfonate monooxygenase MsuD compare
PP_0803 +0.5 3.1 Protein secretion ABC efflux system, membrane fusion protein compare
PP_0629 +0.5 2.6 conserved membrane protein of unknown function compare
PP_0685 +0.5 1.7 conserved protein of unknown function compare
PP_4503 +0.5 2.1 DNA-binding response regulator compare
PP_t64 +0.5 1.7 tRNA-Gly compare
PP_0238 +0.5 2.4 alkanesulfonate monooxygenase compare
PP_5428 +0.5 2.4 conserved exported protein of unknown function compare
PP_1110 +0.5 1.6 serine acetyltransferase compare
PP_5610 +0.5 1.3 protein of unknown function compare
PP_2442 +0.5 1.5 conserved protein of unknown function, DUF480 family compare
PP_5456 +0.5 0.9 conserved protein of unknown function compare
PP_2417 +0.5 1.8 putative Iron ABC transporter, permease protein compare
PP_5317 +0.5 1.0 Probable chorismate pyruvate-lyase compare
PP_5184 +0.5 2.3 glutamylpolyamine synthetase compare
PP_5477 +0.5 2.3 conserved protein of unknown function compare
PP_0801 +0.5 1.0 conserved exported protein of unknown function compare
PP_3211 +0.5 2.5 ABC transporter, ATP-binding protein compare
PP_1731 +0.5 1.2 23S rRNA (746) and tRNA (32) pseudouridine synthase compare
PP_1384 +0.5 2.6 Probable efflux pump outer membrane protein TtgC compare
PP_5549 +0.5 2.1 conserved protein of unknown function compare
PP_2650 +0.5 2.1 putative 4-hydroxybutyrate dehydrogenase compare
PP_1082 +0.5 2.2 bacterioferritin compare
PP_2813 +0.5 1.9 BNR domain protein compare
PP_2568 +0.5 0.8 Ring-cleaving dioxygenase compare
PP_2633 +0.5 1.3 conserved protein of unknown function compare
PP_1829 +0.5 1.3 Hydrolase, alpha/beta fold family compare
PP_5393 +0.5 0.6 putative metal-binding chaperone compare
PP_2107 +0.5 0.8 conserved protein of unknown function compare
PP_0198 +0.5 2.4 putative transporter compare
PP_5565 +0.5 2.0 conserved protein of unknown function compare
PP_4054 +0.5 1.6 conserved protein of unknown function compare
PP_4828 +0.5 0.8 Precorrin-8X methylmutase compare
PP_5495 +0.5 0.8 protein of unknown function compare
PP_2231 +0.5 1.9 putative permease of the drug/metabolite transporter (DMT) superfamily compare
PP_3481 +0.4 1.7 conserved exported protein of unknown function compare
PP_2405 +0.4 2.7 conserved exported protein of unknown function compare
PP_5066 +0.4 2.1 K(+)/H(+) antiporter NhaP2 compare
PP_2907 +0.4 1.9 DNA-binding response regulator compare
PP_3971 +0.4 0.8 conserved protein of unknown function compare
PP_3738 +0.4 1.3 putative Transcriptional regulator VanR compare
PP_4100 +0.4 2.1 Transcriptional regulator, Cro/CI family compare
PP_4848 +0.4 1.0 Curved DNA-binding protein compare
PP_0804 +0.4 3.1 Protein secretion ABC efflux system, permease and ATP-binding protein compare
PP_3726 +0.4 0.8 Enoyl-CoA hydratase/isomerase family protein compare
PP_0711 +0.4 1.5 putative hydrolase compare
PP_4485 +0.4 3.1 histidine / lysine / arginine / ornithine ABC transporter - permease subunit compare
PP_0806 +0.4 4.1 putative Surface adhesion protein compare
PP_1834 +0.4 1.7 conserved protein of unknown function compare
PP_5617 +0.4 1.6 conserved protein of unknown function compare
PP_2361 +0.4 2.6 putative chaperone protein compare
PP_1208 +0.4 1.0 conserved protein of unknown function, SlyX family compare
PP_3880 +0.4 0.9 conserved exported protein of unknown function compare
PP_2319 +0.4 2.2 conserved protein of unknown function compare
PP_2217 +0.4 1.8 enoyl-CoA hydratase compare
PP_0782 +0.4 1.2 conserved protein of unknown function compare
PP_4419 +0.4 0.8 transposase compare
PP_3831 +0.4 1.7 conserved protein of unknown function compare
PP_3411 +0.4 0.6 conserved protein of unknown function compare
PP_0213 +0.4 2.4 succinate-semialdehyde dehydrogenase (NADP+) compare
PP_2041 +0.4 1.8 Transcriptional regulator, LysR family compare
PP_3756 +0.4 1.7 TetR family transcriptional regulator compare
PP_3509 +0.4 1.8 Glyoxalase family protein compare
PP_4271 +0.4 0.7 conserved protein of unknown function compare
PP_2681 +0.4 0.9 coenzyme PQQ synthesis protein D compare
PP_0509 +0.4 1.3 conserved protein of unknown function compare
PP_4273 +0.4 0.6 Transcriptional regulator, MerR family compare
PP_1656 +0.4 2.5 ATP:GTP 3'-pyrophosphotransferase compare
PP_5659 +0.4 1.9 protein of unknown function compare
PP_0620 +0.4 2.0 GntR family transcriptional regulator compare
PP_5441 +0.4 1.4 protein of unknown function compare
PP_3094 +0.4 2.1 conserved exported protein of unknown function compare
PP_2510 +0.4 1.3 conserved protein of unknown function compare
PP_4850 +0.4 2.4 conserved membrane protein of unknown function compare
PP_3454 +0.4 2.4 putative transcriptional regulatory protein compare
PP_2031 +0.4 1.2 conserved protein of unknown function compare
PP_4925 +0.4 1.1 conserved protein of unknown function compare
PP_4199 +0.4 0.8 putative Lipoprotein compare
PP_0805 +0.4 2.6 Outer membrane efflux protein compare
PP_1007 +0.4 2.5 putative Transmembrane sensor compare
PP_2472 +0.4 2.3 putative transcriptional regulator, MerR family compare
PP_1152 +0.4 2.6 putative membrane fusion efflux protein compare
PP_1808 +0.4 1.5 glucose-6-phosphate isomerase compare
PP_0232 +0.4 0.7 ATP-binding taurine transporter subunit compare
PP_1459 +0.4 1.9 CBS domain protein compare
PP_4266 +0.4 1.9 Adenine phosphoribosyltransferase compare
PP_2281 +0.4 2.1 putative Capsid assembly protein compare
PP_5671 +0.4 1.8 conserved protein of unknown function compare
PP_2572 +0.4 1.9 conserved protein of unknown function compare
PP_4743 +0.4 2.5 conserved protein of unknown function compare
PP_2525 +0.4 1.8 conserved protein of unknown function compare
PP_0178 +0.4 2.9 putative efflux pump compare
PP_3254 +0.4 1.7 putative Nucleosidase compare
PP_0944 +0.4 2.5 fumarate hydratase (class 2) compare
PP_3110 +0.4 1.4 protein of unknown function compare
PP_4947 +0.4 3.2 proline dehydrogenase/1-pyrroline-5-carboxylate dehydrogenase compare
PP_4722 +0.4 1.5 Transcription elongation factor GreA compare
PP_0697 +0.4 2.4 ribosomal-protein-S18-alanine N-acetyltransferase compare
PP_4930 +0.4 1.8 putative small multidrug resistance protein compare
PP_0058 +0.4 3.7 putative 1-acyl-sn-glycerol-3-phosphate acyltransferase compare
PP_3916 +0.4 1.1 conserved protein of unknown function compare
PP_0231 +0.4 2.2 taurine ABC transporter permease subunit compare
PP_4418 +0.4 1.4 conserved protein of unknown function compare
PP_1111 +0.4 1.8 putative Synthetase compare
PP_3098 +0.4 0.8 conserved protein of unknown function compare
PP_4328 +0.4 1.0 conserved protein of unknown function compare
PP_2953 +0.4 2.3 Alcohol dehydrogenase, zinc-containing compare
PP_1150 +0.4 2.5 putative Membrane protein compare
PP_4470 +0.4 1.0 putative transcriptional regulator (Arc domain-containing) compare
PP_5139 +0.4 1.9 cadmium translocating P-type ATPase compare
PP_4705 +0.4 2.0 Glyoxalase compare
PP_1812 +0.4 0.8 conserved protein of unknown function compare
PP_0679 +0.4 2.5 conserved exported protein of unknown function compare
PP_0630 +0.4 0.6 DNA gyrase inhibitor YacG compare
PP_5486 +0.4 1.4 conserved protein of unknown function compare
PP_4936 +0.4 1.5 O-antigen polymerase compare
PP_1546 +0.4 2.0 conserved protein of unknown function compare
PP_4608 +0.4 2.3 RNA polymerase sigma-70 factor, ECF subfamily compare
PP_2826 +0.4 1.1 Transcriptional regulator MexT compare
PP_5315 +0.4 1.3 Rubredoxin-1 compare
PP_3546 +0.4 2.6 Sensory box histidine kinase/response regulator compare
PP_2458 +0.4 2.7 ribokinase compare
PP_0674 +0.4 2.8 ADP/ATP ratio sensor and inhibitor of translation compare
PP_0598 +0.4 2.8 paraquat-inducible protein A compare


Specific Phenotypes

For 13 genes in this experiment

For carbon source Vanillic Acid in Pseudomonas putida KT2440

For carbon source Vanillic Acid across organisms