Experiment set12IT035 for Escherichia coli BW25113

Compare to:

LB with phage

200 most important genes:

  gene name fitness t score description  
b2317 dedA -5.5 -5.3 conserved inner membrane protein (NCBI) compare
b2038 rfbC -5.4 -3.7 dTDP-4-deoxyrhamnose-3,5-epimerase (NCBI) compare
b1334 fnr -5.1 -3.5 DNA-binding transcriptional dual regulator, global regulator of anaerobic growth (NCBI) compare
b2040 rfbD -5.0 -4.9 dTDP-4-dehydrorhamnose reductase subunit, NAD(P)-binding, of dTDP-L-rhamnose synthase (NCBI) compare
b2188 yejM -4.8 -9.1 predicted hydrolase, inner membrane (NCBI) compare
b2512 yfgL -4.6 -3.2 protein assembly complex, lipoprotein component (NCBI) compare
b2259 pmrD -4.5 -1.4 polymyxin resistance protein B (VIMSS) compare
b2617 smpA -4.4 -4.1 small membrane protein A (VIMSS) compare
b0178 hlpA -4.2 -5.2 periplasmic chaperone (NCBI) compare
b0957 ompA -3.9 -5.3 outer membrane protein A (3a;II*;G;d) (NCBI) compare
b3199 yrbK -3.9 -3.4 hypothetical protein (NCBI) compare
b3784 rfe -3.7 -15.6 UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase (NCBI) compare
b3794 rffM -3.7 -8.4 putative UDP-N-acetyl-D-mannosaminuronic acid transferase (NCBI) compare
b1256 ompW -3.6 -11.2 outer membrane protein W (NCBI) compare
b3842 rfaH -3.6 -3.5 transcriptional activator RfaH (NCBI) compare
b1677 lpp -3.4 -2.8 murein lipoprotein (NCBI) compare
b1192 ldcA -3.4 -7.5 L,D-carboxypeptidase A (NCBI) compare
b3787 rffD -3.3 -13.4 UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase (NCBI) compare
b1830 prc -3.2 -5.3 carboxy-terminal protease for penicillin-binding protein 3 (NCBI) compare
b3778 rep -3.2 -5.4 DNA helicase and single-stranded DNA-dependent ATPase (NCBI) compare
b3791 rffA -3.2 -8.2 TDP-4-oxo-6-deoxy-D-glucose transaminase (NCBI) compare
b4481 rffT -3.2 -7.5 4-alpha-L-fucosyltransferase (NCBI) compare
b0929 ompF -3.1 -8.5 outer membrane porin 1a (Ia;b;F) (NCBI) compare
b3786 rffE -3.1 -15.5 UDP-N-acetyl glucosamine-2-epimerase (NCBI) compare
b2531 iscR -3.1 -2.3 DNA-binding transcriptional repressor (NCBI) compare
b0082 mraW -3.1 -4.6 S-adenosyl-methyltransferase (NCBI) compare
b3790 rffC -3.1 -6.0 TDP-fucosamine acetyltransferase (RefSeq) compare
b0053 surA -3.0 -4.5 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b1855 lpxM -2.9 -7.3 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase (NCBI) compare
b3627 rfaI -2.8 -1.9 UDP-D-galactose:(glucosyl)lipopolysaccharide- alpha-1,3-D-galactosyltransferase (NCBI) compare
b3620 rfaF -2.8 -3.3 ADP-heptose:LPS heptosyltransferase II (NCBI) compare
b0145 dksA -2.8 -1.9 DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) compare
b2571 rseB -2.7 -6.9 periplasmic negative regulator of sigmaE (NCBI) compare
b3052 rfaE -2.7 -5.1 fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) compare
b3035 tolC -2.7 -9.6 outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes (VIMSS) compare
b0840 deoR -2.7 -4.4 DNA-binding transcriptional repressor (NCBI) compare
b3628 rfaB -2.6 -2.6 UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase (RefSeq) compare
b0741 pal -2.6 -3.5 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b1613 manA -2.6 -2.4 mannose-6-phosphate isomerase (VIMSS) compare
b3387 dam -2.5 -13.0 DNA adenine methylase (NCBI) compare
b3630 rfaP -2.5 -2.5 kinase that phosphorylates core heptose of lipopolysaccharide (NCBI) compare
b3375 yhfR -2.5 -7.9 putative transcriptional regulator (VIMSS) compare
b0222 lpcA -2.4 -3.2 phosphoheptose isomerase (NCBI) compare
b2572 rseA -2.4 -5.1 anti-sigma factor (NCBI) compare
b3163 nlpI -2.4 -5.2 hypothetical protein (NCBI) compare
b3792 wzxE -2.3 -6.4 O-antigen translocase (NCBI) compare
b0739 tolA -2.2 -1.5 cell envelope integrity inner membrane protein TolA (NCBI) compare
b3621 rfaC -2.2 -3.7 ADP-heptose:LPS heptosyl transferase I (NCBI) compare
b2620 smpB -2.2 -1.3 SsrA-binding protein (NCBI) compare
b3613 yibP -2.1 -1.5 putative membrane protein (VIMSS) compare
b2808 gcvA -2.0 -4.0 DNA-binding transcriptional dual regulator (NCBI) compare
b4676 yoaK -2.0 -0.8 expressed protein (RefSeq) compare
b2501 ppk -2.0 -8.4 polyphosphate kinase (NCBI) compare
b1863 ruvC -1.9 -2.5 Holliday junction resolvase (NCBI) compare
b0436 tig -1.9 -5.2 trigger factor (NCBI) compare
b2064 asmA -1.9 -6.2 predicted assembly protein (NCBI) compare
b4171 miaA -1.9 -2.2 tRNA delta(2)-isopentenylpyrophosphate transferase (NCBI) compare
b3632 rfaQ -1.8 -14.2 lipopolysaccharide core biosynthesis protein (NCBI) compare
b0049 apaH -1.8 -3.2 diadenosinetetraphosphatase (NCBI) compare
b2017 yefM -1.8 -0.8 orf, hypothetical protein (VIMSS) compare
b0737 tolQ -1.8 -2.1 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b1095 fabF -1.8 -5.3 3-oxoacyl-(acyl carrier protein) synthase (NCBI) compare
b0740 tolB -1.8 -4.7 translocation protein TolB precursor (NCBI) compare
b3839 tatC -1.8 -6.8 TatABCE protein translocation system subunit (NCBI) compare
b0065 yabI -1.7 -4.5 conserved inner membrane protein (NCBI) compare
b3026 qseC -1.7 -1.6 sensory histidine kinase in two-component regulatory system with QseB (NCBI) compare
b0018 mokC -1.7 -1.2 regulatory protein for HokC, overlaps CDS of hokC (NCBI) compare
b0200 gmhB -1.6 -1.1 hypothetical protein (NCBI) compare
b2830 nudH -1.6 -1.1 dinucleoside polyphosphate hydrolase (NCBI) compare
b3619 rfaD -1.6 -3.0 ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) compare
b0688 pgm -1.6 -3.3 phosphoglucomutase (NCBI) compare
b0759 galE -1.6 -5.2 UDP-galactose-4-epimerase (VIMSS) compare
b4603 rseX -1.6 -0.6 sRNA regulating ompA and ompC translation, with Hfq (RefSeq) compare
b3934 cytR -1.6 -5.6 DNA-binding transcriptional dual regulator (NCBI) compare
b3192 yrbC -1.5 -6.2 predicted ABC-type organic solvent transporter (NCBI) compare
b0617 citD -1.5 -2.7 citrate lyase, acyl carrier (gamma) subunit (NCBI) compare
b2346 vacJ -1.5 -5.5 predicted lipoprotein (NCBI) compare
b3609 secB -1.5 -2.8 export protein SecB (NCBI) compare
b0463 acrA -1.5 -6.9 multidrug efflux system (NCBI) compare
b3426 glpD -1.4 -2.2 sn-glycerol-3-phosphate dehydrogenase, aerobic, FAD/NAD(P)-binding (NCBI) compare
b3190 yrbA -1.4 -3.6 orf, hypothetical protein (VIMSS) compare
b0998 torD -1.4 -0.9 chaperone protein TorD (NCBI) compare
b3742 mioC -1.4 -3.2 flavodoxin (NCBI) compare
b4685 yrbN -1.4 -2.6 expressed protein (RefSeq) compare
b1627 rsxA -1.4 -2.5 Na(+)-translocating NADH-quinone reductase subunit E (NCBI) compare
b2934 cmtB -1.4 -0.8 predicted mannitol-specific enzyme IIA component of PTS (NCBI) compare
b3009 yghB -1.4 -4.5 conserved inner membrane protein (NCBI) compare
b0406 tgt -1.3 -4.6 queuine tRNA-ribosyltransferase (NCBI) compare
b2248 yfaX -1.3 -1.6 predicted DNA-binding transcriptional regulator (NCBI) compare
b0738 tolR -1.3 -1.5 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b2175 spr -1.3 -3.1 predicted peptidase, outer membrane lipoprotein (NCBI) compare
b3443 yrhA -1.3 -1.3 orf, hypothetical protein (VIMSS) compare
b1548 nohA -1.3 -1.5 Qin prophage; predicted packaging protein (RefSeq) compare
b3191 yrbB -1.3 -4.3 orf, hypothetical protein (VIMSS) compare
b1926 fliT -1.3 -2.7 predicted chaperone (NCBI) compare
b4146 yjeK -1.3 -0.9 predicted lysine aminomutase (NCBI) compare
b4535 yniD -1.3 -1.1 predicted protein (RefSeq) compare
b3082 ygjM -1.3 -1.4 predicted DNA-binding transcriptional regulator (NCBI) compare
b3150 yraP -1.3 -5.1 hypothetical protein (NCBI) compare
b0015 dnaJ -1.3 -4.8 chaperone Hsp40, co-chaperone with DnaK (NCBI) compare
b1134 ymfB -1.3 -1.3 bifunctional thiamin pyrimidine pyrophosphate hydrolase/ thiamin pyrophosphate hydrolase (NCBI) compare
b4402 yjjY -1.3 -0.9 hypothetical protein (NCBI) compare
b0232 yafN -1.3 -0.5 predicted antitoxin of the YafO-YafN toxin-antitoxin system (NCBI) compare
b2258 b2258 -1.2 -0.9 putative transport/receptor protein (VIMSS) compare
b0122 yacC -1.2 -2.7 orf, hypothetical protein (VIMSS) compare
b0462 acrB -1.2 -7.3 multidrug efflux system protein (NCBI) compare
b1727 yniC -1.2 -2.6 predicted hydrolase (NCBI) compare
b1175 minD -1.2 -3.2 membrane ATPase of the MinC-MinD-MinE system (NCBI) compare
b2894 xerD -1.2 -0.8 site-specific tyrosine recombinase XerD (NCBI) compare
b3195 yrbF -1.2 -5.1 predicted toluene transporter subunit: ATP-binding component of ABC superfamily (NCBI) compare
b2569 lepA -1.2 -3.6 GTP-binding protein LepA (NCBI) compare
b3629 rfaS -1.2 -0.8 lipopolysaccharide core biosynthesis protein (NCBI) compare
b4144 yjeI -1.2 -2.8 orf, hypothetical protein (VIMSS) compare
b1861 ruvA -1.2 -1.1 Holliday junction DNA helicase motor protein (NCBI) compare
b1919 yedO -1.2 -3.0 putative 1-aminocyclopropane-1-carboxylate deaminase (VIMSS) compare
b1007 b1007 -1.2 -1.2 orf, hypothetical protein (VIMSS) compare
b1370 insH-5 -1.2 -1.6 Rac prophage; IS5 transposase and trans-activator (NCBI) compare
b3194 yrbE -1.2 -5.5 predicted toluene transporter subunit: membrane component of ABC superfamily (NCBI) compare
b2168 fruK -1.2 -1.1 1-phosphofructokinase (NCBI) compare
b2614 grpE -1.2 -1.5 heat shock protein (NCBI) compare
b3706 trmE -1.2 -3.5 tRNA modification GTPase (NCBI) compare
b1253 yciA -1.1 -2.8 predicted hydrolase (NCBI) compare
b0580 ybdJ -1.1 -1.6 predicted inner membrane protein (NCBI) compare
b4505 insX -1.1 -1.0 predicted IS protein (RefSeq) compare
b3021 ygiT -1.1 -1.6 predicted DNA-binding transcriptional regulator (NCBI) compare
b0149 mrcB -1.1 -7.2 penicillin-binding protein 1b (NCBI) compare
b1693 aroD -1.1 -4.8 3-dehydroquinate dehydratase (NCBI) compare
b0565 ompT -1.1 -6.9 DLP12 prophage; outer membrane protease VII (outer membrane protein 3b) (NCBI) compare
b1248 b1248 -1.1 -2.0 orf, hypothetical protein (VIMSS) compare
b2768 ygcP -1.1 -2.3 predicted anti-terminator regulatory protein (NCBI) compare
b0965 b0965 -1.1 -2.0 orf, hypothetical protein (VIMSS) compare
b3625 rfaY -1.1 -1.6 lipopolysaccharide core biosynthesis protein (NCBI) compare
b2174 b2174 -1.1 -4.3 orf, hypothetical protein (VIMSS) compare
b0682 ybfN -1.1 -2.5 predicted lipoprotein (NCBI) compare
b1176 minC -1.1 -2.5 septum formation inhibitor (NCBI) compare
b2083 yegZ -1.1 -1.4 orf, hypothetical protein (VIMSS) compare
b0161 degP -1.0 -5.3 serine endoprotease (protease Do), membrane-associated (NCBI) compare
b1361 ydaW -1.0 -0.4 orf, hypothetical protein (VIMSS) compare
b2204 napH -1.0 -3.1 quinol dehydrogenase membrane component (NCBI) compare
b4631 ykgQ -1.0 -0.8 no description compare
b0882 clpA -1.0 -4.8 ATPase and specificity subunit of ClpA-ClpP ATP-dependent serine protease, chaperone activity (NCBI) compare
b3741 gidA -1.0 -2.0 glucose-inhibited division protein A (NCBI) compare
b2784 relA -1.0 -5.4 (p)ppGpp synthetase I/GTP pyrophosphokinase (NCBI) compare
b4042 dgkA -1.0 -1.3 diacylglycerol kinase (NCBI) compare
b0696 kdpC -1.0 -2.3 potassium-transporting ATPase subunit C (NCBI) compare
b2329 aroC -1.0 -2.7 chorismate synthase (NCBI) compare
b0890 ftsK -1.0 -2.6 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b3838 tatB -1.0 -4.3 sec-independent translocase (NCBI) compare
b1296 ycjJ -1.0 -2.4 putative amino acid/amine transport protein (VIMSS) compare
b4451 ryhB -1.0 -1.2 Regulatory sRNA mediating positive Fur regulon response; requires Hfq for function; global iron regulator; degraded by RNase E when bound to target (RefSeq) compare
b3260 dusB -1.0 -4.5 tRNA-dihydrouridine synthase B (NCBI) compare
b3162 deaD -1.0 -3.0 inducible ATP-independent RNA helicase (VIMSS) compare
b4178 yjeB -1.0 -3.4 predicted DNA-binding transcriptional regulator (NCBI) compare
b3075 ebgR -1.0 -2.7 DNA-binding transcriptional repressor (NCBI) compare
b2749 ygbE -1.0 -2.7 conserved inner membrane protein (NCBI) compare
b3626 rfaJ -1.0 -2.6 UDP-D-glucose:(galactosyl)lipopolysaccharide glucosyltransferase (NCBI) compare
b2448 yffQ -1.0 -2.0 CPZ-55 prophage; predicted protein (RefSeq) compare
b0439 lon -1.0 -3.3 DNA-binding ATP-dependent protease La (NCBI) compare
b1259 yciG -1.0 -1.3 orf, hypothetical protein (VIMSS) compare
b4701 sokX -1.0 -0.6 sok-related sRNA, function unknown (RefSeq) compare
b3193 yrbD -0.9 -4.3 predicted ABC-type organic solvent transporter (NCBI) compare
b1148 ymfM -0.9 -2.1 e14 prophage; predicted protein (NCBI) compare
b2498 upp -0.9 -2.0 uracil phosphoribosyltransferase (VIMSS) compare
b2050 wcaI -0.9 -2.4 predicted glycosyl transferase (NCBI) compare
b0677 nagA -0.9 -3.6 N-acetylglucosamine-6-phosphate deacetylase (NCBI) compare
b1074 flgC -0.9 -1.6 flagellar basal-body rod protein C (NCBI) compare
b4596 yciZ -0.9 -1.4 hypothetical protein (RefSeq) compare
b2642 yfjW -0.9 -0.8 CP4-57 prophage; predicted inner membrane protein (NCBI) compare
b2236 yfaE -0.9 -2.0 predicted 2Fe-2S cluster-containing protein (NCBI) compare
b2939 yqgB -0.9 -1.1 predicted protein (RefSeq) compare
b1332 ynaJ -0.9 -0.3 predicted inner membrane protein (NCBI) compare
b2058 wcaB -0.9 -0.7 predicted acyl transferase (NCBI) compare
b0780 ybhK -0.9 -3.3 predicted transferase with NAD(P)-binding Rossmann-fold domain (NCBI) compare
b2910 zapA -0.9 -2.9 protein that localizes to the cytokinetic ring (NCBI) compare
b3181 greA -0.9 -2.3 transcription elongation factor: cleaves 3' nucleotide of paused mRNA (VIMSS) compare
b4426 isrA -0.9 -1.5 unknown RNA (NCBI) compare
b4191 ulaR -0.9 -2.8 DNA-binding transcriptional dual regulator (NCBI) compare
b3916 pfkA -0.9 -1.3 6-phosphofructokinase (NCBI) compare
b2912 ygfA -0.9 -2.2 putative ligase (VIMSS) compare
b3243 aaeR -0.9 -2.5 predicted DNA-binding transcriptional regulator, efflux system (NCBI) compare
b1185 dsbB -0.8 -1.4 reoxidizes DsbA protein following formation of disulfide bond in P-ring of flagella. (VIMSS) compare
b1349 recT -0.8 -2.8 Rac prophage; recombination and repair protein (NCBI) compare
b1380 ldhA -0.8 -1.3 D-lactate dehydrogenase (NCBI) compare
b3788 rffG -0.8 -4.8 dTDP-glucose 4,6-dehydratase (NCBI) compare
b0865 ybjP -0.8 -2.1 predicted lipoprotein (NCBI) compare
b4477 dgoA -0.8 -3.0 2-dehydro-3-deoxy-6-phosphogalactonate aldolase (NCBI) compare
b1632 rsxE -0.8 -3.3 NADH-ubiquinone oxidoreductase (NCBI) compare
b2428 yfeU -0.8 -2.7 N-acetylmuramic acid-6-phosphate etherase (NCBI) compare
b3858 yihD -0.8 -1.5 hypothetical protein (NCBI) compare
b0051 ksgA -0.8 -2.5 dimethyladenosine transferase (NCBI) compare
b1920 fliY -0.8 -1.8 cystine transporter subunit (NCBI) compare
b2666 yqaE -0.8 -2.1 predicted membrane protein (NCBI) compare
b1628 rsxB -0.8 -1.2 electron transport complex protein RnfB (NCBI) compare
b1831 proQ -0.8 -1.3 putative solute/DNA competence effector (NCBI) compare
b2823 ppdC -0.8 -2.5 hypothetical protein (NCBI) compare
b4373 rimI -0.8 -1.7 ribosomal-protein-alanine N-acetyltransferase (NCBI) compare
b3146 yraL -0.8 -2.8 predicted methyltransferase (NCBI) compare
b4567 yjjZ -0.8 -2.2 hypothetical protein (NCBI) compare
b1506 yneL -0.8 -1.1 predicted transcriptional regulator (NCBI) compare
b1841 yobA -0.8 -1.2 hypothetical protein (NCBI) compare


Specific Phenotypes

For 9 genes in this experiment

For phage Phage need info in Escherichia coli BW25113

For phage Phage need info across organisms