Experiment set12IT032 for Pseudomonas putida KT2440

Compare to:

1,2-Propanediol carbon source

200 most important genes:

  gene name fitness t score description  
PP_4364 -8.2 -5.6 putative Anti-sigma F factor antagonist compare
PP_5098 -7.4 -5.1 methionine biosynthesis protein MetW compare
PP_1985 -7.2 -7.1 3-isopropylmalate dehydratase large subunit compare
PP_0967 -7.0 -11.8 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
PP_1988 -6.8 -10.3 3-isopropylmalate dehydrogenase compare
PP_5097 -6.7 -13.6 homoserine O-acetyltransferase compare
PP_0966 -6.6 -11.9 Histidinol dehydrogenase compare
PP_5014 -6.6 -4.5 Phosphoribosyl-AMP cyclohydrolase compare
PP_3511 -6.5 -10.8 Branched-chain-amino-acid aminotransferase compare
PP_0422 -6.4 -7.6 Indole-3-glycerol phosphate synthase compare
PP_1995 -6.4 -6.2 N-(5'-phosphoribosyl)anthranilate isomerase compare
PP_4678 -6.4 -16.5 Ketol-acid reductoisomerase compare
PP_5015 -6.3 -6.1 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
PP_0290 -6.2 -6.0 Imidazole glycerol phosphate synthase subunit HisH compare
PP_4680 -6.0 -16.4 acetohydroxybutanoate synthase / acetolactate synthase compare
PP_4890 -6.0 -6.3 ATP phosphoribosyltransferase regulatory subunit compare
PP_0417 -5.9 -22.8 Anthranilate synthase component 1 compare
PP_4723 -5.9 -9.1 Carbamoyl-phosphate synthase large chain compare
PP_4679 -5.9 -8.0 acetohydroxybutanoate synthase / acetolactate synthase compare
PP_3484 -5.9 -8.0 Response regulator receiver protein compare
PP_4736 -5.8 -16.2 L-lactate dehydrogenase compare
PP_1088 -5.6 -9.3 Argininosuccinate synthase compare
PP_0421 -5.5 -8.9 Anthranilate phosphoribosyltransferase compare
PP_0691 -5.5 -5.4 Glutamate 5-kinase compare
PP_5347 -5.4 -14.0 pyruvate carboxylase subunit A compare
PP_2168 -5.4 -13.5 Transaldolase compare
PP_0083 -5.4 -3.7 tryptophan synthase beta chain compare
PP_0420 -5.2 -13.0 aminodeoxychorismate synthase / para-aminobenzoate synthase multi-enzyme complex compare
PP_1079 -5.2 -8.0 Ornithine carbamoyltransferase compare
PP_5346 -5.2 -11.5 pyruvate carboxylase subunit B compare
PP_2370 -5.1 -5.0 conserved protein of unknown function compare
PP_0082 -5.0 -3.5 tryptophan synthase alpha chain compare
PP_0184 -5.0 -3.5 Argininosuccinate lyase compare
PP_5348 -5.0 -13.5 Transcriptional regulator, LysR family compare
PP_4735 -4.9 -11.2 L-lactate permease compare
PP_0164 -4.9 -10.9 conserved protein of unknown function compare
PP_4724 -4.9 -7.4 Carbamoyl-phosphate synthase small chain compare
PP_2001 -4.8 -9.6 O-succinylhomoserine sulfhydrylase compare
PP_4909 -4.7 -11.0 phosphoserine phosphatase compare
PP_0289 -4.7 -8.4 Imidazoleglycerol-phosphate dehydratase compare
PP_0965 -4.6 -8.7 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
PP_5128 -4.6 -7.8 Dihydroxy-acid dehydratase compare
PP_5095 -4.6 -3.2 pyrroline-5-carboxylate reductase compare
PP_1986 -4.6 -5.4 3-isopropylmalate dehydratase small subunit compare
PP_0339 -4.5 -3.1 Pyruvate dehydrogenase E1 component compare
PP_4799 -4.5 -3.1 putative Muramoyltetrapeptide carboxypeptidase compare
PP_3999 -4.5 -10.5 Uroporphyrinogen-III C-methyltransferase/Precorrin-2 dehydrogenase/Sirohydrochlorin ferrochelatase compare
PP_4999 -4.5 -3.1 dihydroorotase-like protein compare
PP_5185 -4.4 -8.3 acetylglutamate kinase-like protein (regulatory domain)/amino acid N-acetyltransferase compare
PP_1233 -4.4 -7.8 sulfurtransferase compare
PP_2388 -4.3 -5.5 Transporter, LysE family compare
PP_0292 -4.1 -3.6 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
PP_4696 -4.1 -2.8 Nitrogen regulation protein NR(I) compare
PP_5289 -4.1 -6.0 Acetylglutamate kinase compare
PP_0293 -4.0 -3.2 Imidazole glycerol phosphate synthase subunit HisF compare
PP_5155 -3.9 -5.1 D-3-phosphoglycerate dehydrogenase / alpha-ketoglutarate reductase compare
PP_2327 -3.8 -7.3 transcriptional dual regulator / CysB-O-acetyl-L-serine compare
PP_2371 -3.8 -9.1 Sulphite reductase hemoprotein, beta subunit compare
PP_4782 -3.6 -6.7 Phosphomethylpyrimidine kinase compare
PP_1231 -3.6 -9.4 quinolinate synthase [4Fe-4S] cluster subunit compare
PP_4994 -3.4 -6.1 conserved protein of unknown function compare
PP_5303 -3.3 -5.5 aminoacrylate/iminopropionate hydrolase/deaminase compare
PP_4943 -3.3 -3.2 putative Glycosyl transferase compare
PP_5104 -3.2 -8.1 thiazole synthase compare
PP_4700 -3.0 -2.1 pantothenate synthetase compare
PP_0735 -3.0 -3.4 molybdopterin-synthase adenylyltransferase compare
PP_1025 -3.0 -7.5 2-isopropylmalate synthase compare
PP_5217 -2.8 -13.9 Polyphosphate kinase compare
PP_1898 -2.8 -4.0 MotA/TolQ/ExbB proton channel family protein compare
PP_0362 -2.8 -12.3 Biotin synthase compare
PP_0291 -2.7 -2.4 conserved protein of unknown function compare
PP_1348 -2.6 -8.4 putative MutT/nudix family protein/thiamine-phosphate pyrophosphorylase compare
PP_0787 -2.5 -6.0 quinolinate phosphoribosyltransferase (decarboxylating) monomer compare
PP_2390 -2.5 -9.5 Transcriptional regulator, LysR family compare
PP_2682 -2.4 -8.0 Fe-containing alcohol dehydrogenase compare
PP_1994 -2.3 -2.2 tRNA pseudouridine (38-40)synthase compare
PP_0365 -2.3 -9.6 Malonyl-[acyl-carrier protein] O-methyltransferase compare
PP_2414 -2.3 -1.8 conserved exported protein of unknown function compare
PP_0364 -2.3 -8.3 pimeloyl-[acp] methyl ester esterase compare
PP_4828 -2.2 -2.1 Precorrin-8X methylmutase compare
PP_3821 -2.2 -8.7 UTP-glucose-1-phosphate uridylyltransferase compare
PP_4984 -2.2 -11.8 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase compare
PP_2665 -2.2 -7.8 Glycerol metabolism activator compare
PP_0356 -2.2 -8.8 malate synthase G compare
PP_0363 -2.2 -10.5 8-amino-7-oxononanoate synthase compare
PP_4922 -2.2 -11.2 Phosphomethylpyrimidine synthase compare
PP_2328 -2.1 -6.2 Phosphoadenosine phosphosulfate reductase compare
PP_0393 -2.0 -2.6 putative 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase compare
PP_1734 -1.9 -2.2 Probable septum site-determining protein MinC compare
PP_2299 -1.8 -2.3 Trigger factor compare
PP_1217 -1.8 -4.4 Holliday junction ATP-dependent DNA helicase RuvB compare
PP_3662 -1.8 -9.2 conserved protein of unknown function compare
PP_0406 -1.8 -5.8 Nucleotidyltransferase family protein compare
PP_0366 -1.8 -7.7 dethiobiotin synthetase compare
PP_0377 -1.8 -3.2 coenzyme PQQ synthesis protein D compare
PP_0435 -1.7 -12.9 Peptidase, M23/M37 family compare
PP_2000 -1.7 -1.6 amidophosphoribosyl transferase compare
PP_4826 -1.7 -6.9 Precorrin-3B C17-methyltransferase compare
PP_0958 -1.7 -6.0 phospholipid ABC transporter ATP-binding subunit compare
PP_2087 -1.6 -3.0 CmpX protein compare
PP_1216 -1.6 -2.2 Holliday junction ATP-dependent DNA helicase RuvA compare
PP_1654 -1.6 -3.6 cysteine synthase B compare
PP_4126 -1.6 -2.3 NADH-quinone oxidoreductase subunit I compare
PP_1493 -1.6 -1.9 chemotaxis response regulator protein-glutamate methylesterase of group 3 operon compare
PP_2433 -1.5 -2.1 conserved protein of unknown function compare
PP_2680 -1.5 -4.4 aldehyde dehydrogenase compare
PP_1912 -1.5 -4.3 Phosphate acyltransferase compare
PP_3506 -1.5 -5.0 Magnesium chelatase, subunit ChII compare
PP_1677 -1.5 -5.7 Adenosyl-cobyric acid synthase compare
PP_0612 -1.5 -8.4 FAD-dependent glycine/D-amino acid oxidase compare
PP_4737 -1.5 -8.2 D-lactate dehydrogenase compare
PP_4004 -1.5 -2.7 DNA translocase FtsK compare
PP_2683 -1.5 -6.7 putative sensory box histidine kinase/response regulator compare
PP_5230 -1.4 -3.3 Tyrosine recombinase XerC compare
PP_1598 -1.4 -3.8 regulatory intramembrane protein RIP zinc protease compare
PP_4122 -1.4 -2.0 proton-pumping NADH:ubiquinone oxidoreductase, respiratory complex I, subunit E compare
PP_1679 -1.4 -1.8 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase compare
PP_0959 -1.4 -2.2 phospholipid ABC transporter compare
PP_5310 -1.4 -4.5 junction-specific ATP-dependent DNA helicase compare
PP_2031 -1.3 -2.4 conserved protein of unknown function compare
PP_3505 -1.3 -2.3 conserved protein of unknown function compare
PP_5274 -1.3 -3.5 conserved protein of unknown function compare
PP_1215 -1.3 -1.3 Crossover junction endodeoxyribonuclease RuvC compare
PP_4695 -1.3 -6.1 Sensory box histidine kinase compare
PP_5706 -1.3 -1.5 Sec translocation complex - SecG subunit compare
PP_0381 -1.3 -6.8 Coenzyme PQQ synthesis protein F compare
PP_1232 -1.3 -7.2 conserved exported protein of unknown function compare
PP_2163 -1.3 -5.6 VacJ lipoprotein compare
PP_0378 -1.3 -7.8 Pyrroloquinoline-quinone synthase compare
PP_5748 -1.3 -1.9 cytochrome c heme lyase subunit compare
PP_1733 -1.2 -2.2 membrane ATPase of the MinC-MinD-MinE system compare
PP_1427 -1.2 -5.4 RNA polymerase sigma E factor compare
PP_1629 -1.2 -3.9 Protein RecA compare
PP_0653 -1.2 -1.7 conserved protein of unknown function compare
PP_4977 -1.2 -7.7 5,10-methylenetetrahydrofolate reductase compare
PP_3508 -1.2 -2.7 Protein CobW compare
PP_3105 -1.1 -2.5 conserved membrane protein of unknown function compare
PP_0961 -1.1 -5.2 toluene tolerance protein compare
PP_4830 -1.1 -4.6 precorrin-6Y C(5,15)-methyltransferase compare
PP_4940 -1.1 -4.6 Putative glycosyltransferase compare
PP_0547 -1.1 -3.0 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase compare
PP_1673 -1.1 -5.1 cobyrinate a,c-diamide synthase compare
PP_2137 -1.1 -1.9 beta-ketoadipyl CoA thiolase, beta component compare
PP_0960 -1.1 -3.4 phospholipid ABC transporter binding protein compare
PP_3507 -1.1 -7.7 Aerobic cobaltochelatase subunit CobN compare
PP_1681 -1.1 -6.8 cobalamin 5'-phosphate synthase / Cobalamin synthase compare
PP_0914 -1.1 -6.8 GGDEF domain protein compare
PP_0218 -1.1 -7.3 Sensory box protein compare
PP_5538 -1.1 -5.0 putative ABC transporter, substrate-binding protein compare
PP_2671 -1.1 -6.6 Sensor histidine kinase compare
PP_1468 -1.1 -1.5 Tyrosine recombinase XerD compare
PP_2375 -1.1 -8.1 cobalamin-dependent methionine synthase compare
PP_5227 -1.1 -4.4 diaminopimelate decarboxylase compare
PP_1678 -1.1 -3.1 bifunctional cobinamide-P guanylyltransferase - adenosylcobinamide kinase compare
PP_3365 -1.1 -1.8 Acetolactate synthase compare
PP_2136 -1.1 -2.8 enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase compare
PP_0989 -1.1 -3.1 glycine cleavage system H protein 1 compare
PP_5571 -1.0 -1.7 conserved protein of unknown function compare
PP_4379 -1.0 -5.3 Beta-ketoacyl-acyl-carrier-protein synthase I compare
PP_1355 -1.0 -8.8 Muropeptide permease AmpG compare
PP_1426 -1.0 -7.6 L-aspartate oxidase compare
PP_5085 -1.0 -4.2 malic enzyme B compare
PP_3248 -1.0 -1.6 Dyp-type peroxidase family protein compare
PP_4129 -1.0 -2.8 NADH:ubiquinone oxidoreductase, membrane subunit L compare
PP_2475 -1.0 -3.4 Transcriptional regulator, TetR family compare
PP_4895 -1.0 -1.5 tRNA dimethylallyltransferase compare
PP_0376 -1.0 -6.2 Coenzyme PQQ synthesis protein E compare
PP_4726 -1.0 -2.3 Chaperone protein DnaJ compare
PP_1675 -1.0 -5.0 Subunit of adenosylcobinamide-phosphate synthase beta component compare
PP_0962 -1.0 -2.3 toluene-tolerance protein compare
PP_0794 -1.0 -3.4 1-phosphofructokinase monomer compare
PP_1301 -1.0 -4.3 quality control serine endoprotease DegS compare
PP_4804 -1.0 -2.3 RlpA-like lipoprotein compare
PP_0379 -0.9 -4.6 Coenzyme PQQ synthesis protein B compare
PP_4827 -0.9 -5.4 Precorrin-2 C(20)-methyltransferase compare
PP_0065 -0.9 -2.1 NAD-binding component of TrK potassium transporter compare
PP_1764 -0.9 -4.9 Phosphoglycolate phosphatase 2 compare
PP_4340 -0.9 -3.8 response regulator for chemotactic signal transduction compare
PP_2030 -0.9 -2.7 conserved protein of unknown function compare
PP_2668 -0.9 -3.2 ABC efflux transporter, ATP-binding protein compare
PP_2669 -0.9 -5.3 putative Outer membrane protein compare
PP_2378 -0.9 -1.7 Fe/S biogenesis protein NfuA compare
PP_1366 -0.9 -1.7 Transcriptional regulator MvaT, P16 subunit compare
PP_1054 -0.9 -2.2 Type II secretion pathway protein XcpZ compare
PP_4338 -0.9 -5.4 Chemotaxis histidine kinase CheA compare
PP_4480 -0.9 -5.5 arginine N-succinyltransferase, subunit alpha compare
PP_2720 -0.9 -1.4 conserved protein of unknown function compare
PP_0901 -0.9 -4.8 DNA-binding response regulator compare
PP_2145 -0.9 -5.0 beta-N-acetylglucosaminidase compare
PP_1672 -0.9 -2.9 cob(I)alamin adenolsyltransferase/cobinamide ATP-dependent adenolsyltransferase compare
PP_3198 -0.8 -2.1 Ferredoxin, 2Fe-2S compare
PP_2675 -0.8 -3.0 Cytochrome c-type protein compare
PP_2214 -0.8 -3.2 3-hydroxyacyl-CoA dehydrogenase type-2 compare
PP_2028 -0.8 -2.3 conserved protein of unknown function containing tetratricopeptide (TPR) domain repeat compare
PP_1309 -0.8 -4.2 conserved exported protein of unknown function compare
PP_1999 -0.8 -2.0 membrane protein required for colicin V production compare
PP_1783 -0.8 -0.9 dTDP-glucose pyrophosphorylase compare
PP_1676 -0.8 -3.3 subunit of adenosylcobinamide-phosphate synthase beta component compare
PP_2747 -0.8 -1.8 conserved protein of unknown function compare
PP_4989 -0.8 -2.4 Protein PilJ compare


Specific Phenotypes

For 7 genes in this experiment

For carbon source 1,2-Propanediol in Pseudomonas putida KT2440

For carbon source 1,2-Propanediol across organisms