Experiment set12IT032 for Escherichia coli BW25113

Compare to:

LB with phage

200 most important genes:

  gene name fitness t score description  
b0683 fur -2.7 -2.2 ferric uptake regulator (NCBI) compare
b1863 ruvC -2.5 -3.3 Holliday junction resolvase (NCBI) compare
b3183 obgE -2.5 -1.6 GTPase involved in cell partioning and DNA repair (NCBI) compare
b4676 yoaK -2.0 -1.3 expressed protein (RefSeq) compare
b0200 gmhB -1.8 -1.7 hypothetical protein (NCBI) compare
b2279 nuoK -1.6 -2.7 NADH dehydrogenase subunit K (NCBI) compare
b1291 sapD -1.6 -2.2 predicted antimicrobial peptide transporter subunit (NCBI) compare
b2330 yfcB -1.6 -1.7 putative adenine-specific methylase (VIMSS) compare
b0564 appY -1.5 -1.4 DLP12 prophage; DNA-binding transcriptional activator (NCBI) compare
b3979 thrT -1.4 -0.7 tRNA-Thr (NCBI) compare
b0740 tolB -1.4 -4.4 translocation protein TolB precursor (NCBI) compare
b4702 mgtL -1.4 -2.2 regulatory leader peptide for mgtA (NCBI) compare
b1850 eda -1.4 -2.9 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (NCBI) compare
b0049 apaH -1.3 -3.0 diadenosinetetraphosphatase (NCBI) compare
b0730 mngR -1.3 -1.4 DNA-binding transcriptional dual regulator, fatty-acyl-binding (NCBI) compare
b4375 prfC -1.3 -3.0 peptide chain release factor 3 (NCBI) compare
b1192 ldcA -1.2 -5.0 L,D-carboxypeptidase A (NCBI) compare
b2808 gcvA -1.2 -3.6 DNA-binding transcriptional dual regulator (NCBI) compare
b0149 mrcB -1.2 -8.7 penicillin-binding protein 1b (NCBI) compare
b2894 xerD -1.2 -1.0 site-specific tyrosine recombinase XerD (NCBI) compare
b4146 yjeK -1.2 -1.7 predicted lysine aminomutase (NCBI) compare
b1429 tehA -1.2 -1.4 potassium-tellurite ethidium and proflavin transporter (NCBI) compare
b1346 ydaQ -1.1 -1.8 orf, hypothetical protein (VIMSS) compare
b2282 nuoH -1.1 -2.9 NADH dehydrogenase subunit H (NCBI) compare
b3706 trmE -1.1 -3.1 tRNA modification GTPase (NCBI) compare
b2506 yfgI -1.1 -1.8 hypothetical protein (NCBI) compare
b0726 sucA -1.1 -3.1 alpha-ketoglutarate decarboxylase (NCBI) compare
b3613 yibP -1.1 -3.0 putative membrane protein (VIMSS) compare
b3261 fis -1.1 -1.6 DNA-binding protein Fis (NCBI) compare
b4570 lomR -1.0 -2.0 no description compare
b2830 nudH -1.0 -1.1 dinucleoside polyphosphate hydrolase (NCBI) compare
b2614 grpE -0.9 -2.1 heat shock protein (NCBI) compare
b0739 tolA -0.9 -2.3 cell envelope integrity inner membrane protein TolA (NCBI) compare
b1613 manA -0.9 -2.0 mannose-6-phosphate isomerase (VIMSS) compare
b2569 lepA -0.9 -3.1 GTP-binding protein LepA (NCBI) compare
b2528 iscA -0.9 -1.6 iron-sulfur cluster assembly protein (NCBI) compare
b1476 fdnI -0.9 -1.3 formate dehydrogenase-N, cytochrome B556 (gamma) subunit, nitrate-inducible (NCBI) compare
b4171 miaA -0.9 -2.0 tRNA delta(2)-isopentenylpyrophosphate transferase (NCBI) compare
b1524 yneH -0.9 -1.1 predicted glutaminase (NCBI) compare
b4426 isrA -0.9 -2.0 unknown RNA (NCBI) compare
b0167 glnD -0.8 -3.1 PII uridylyl-transferase (NCBI) compare
b0630 lipB -0.8 -1.0 protein of lipoate biosynthesis (VIMSS) compare
b1575 dicB -0.8 -1.6 Qin prophage; cell division inhibition protein (NCBI) compare
b3916 pfkA -0.8 -1.5 6-phosphofructokinase (NCBI) compare
b3002 yqhA -0.8 -2.1 hypothetical protein (NCBI) compare
b0737 tolQ -0.8 -1.7 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b1865 nudB -0.8 -1.6 dATP pyrophosphohydrolase (NCBI) compare
b0688 pgm -0.8 -2.1 phosphoglucomutase (NCBI) compare
b3237 argR -0.8 -2.9 arginine repressor (NCBI) compare
b1567 intK -0.8 -1.7 Qin prophage; predicted protein (RefSeq) compare
b3238 yhcN -0.8 -1.5 orf, hypothetical protein (VIMSS) compare
b0738 tolR -0.8 -1.4 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b4533 ynfO -0.7 -1.5 Qin prophage; predicted protein (NCBI) compare
b2650 ypjC -0.7 -0.4 hypothetical protein (RefSeq) compare
b0741 pal -0.7 -2.1 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b3169 nusA -0.7 -1.9 transcription elongation factor NusA (NCBI) compare
b2286 nuoC -0.7 -3.2 NADH:ubiquinone oxidoreductase, chain C,D (RefSeq) compare
b0232 yafN -0.7 -0.6 predicted antitoxin of the YafO-YafN toxin-antitoxin system (NCBI) compare
b3426 glpD -0.7 -2.0 sn-glycerol-3-phosphate dehydrogenase, aerobic, FAD/NAD(P)-binding (NCBI) compare
b3021 ygiT -0.7 -1.4 predicted DNA-binding transcriptional regulator (NCBI) compare
b1180 ycgM -0.7 -2.7 predicted isomerase/hydrolase (NCBI) compare
b2356 yfdM -0.7 -1.7 orf, hypothetical protein (VIMSS) compare
b4685 yrbN -0.7 -1.7 expressed protein (RefSeq) compare
b2278 nuoL -0.7 -4.2 NADH dehydrogenase subunit L (NCBI) compare
b2934 cmtB -0.7 -0.6 predicted mannitol-specific enzyme IIA component of PTS (NCBI) compare
b4701 sokX -0.7 -0.8 sok-related sRNA, function unknown (RefSeq) compare
b1920 fliY -0.7 -1.7 cystine transporter subunit (NCBI) compare
b4202 rpsR -0.7 -0.8 30S ribosomal protein S18 (NCBI) compare
b1689 b1689 -0.7 -2.0 orf, hypothetical protein (VIMSS) compare
b1742 b1742 -0.7 -1.4 orf, hypothetical protein (VIMSS) compare
b3029 ygiN -0.7 -2.1 quinol monooxygenase (NCBI) compare
b3778 rep -0.6 -3.7 DNA helicase and single-stranded DNA-dependent ATPase (NCBI) compare
b2281 nuoI -0.6 -1.8 NADH dehydrogenase subunit I (NCBI) compare
b0386 proC -0.6 -2.5 pyrroline-5-carboxylate reductase (NCBI) compare
b1348 lar -0.6 -1.4 Rac prophage; restriction alleviation protein (NCBI) compare
b3811 xerC -0.6 -0.9 site-specific tyrosine recombinase XerC (NCBI) compare
b2498 upp -0.6 -1.5 uracil phosphoribosyltransferase (VIMSS) compare
b3164 pnp -0.6 -1.4 polynucleotide phosphorylase/polyadenylase (RefSeq) compare
b2939 yqgB -0.6 -1.4 predicted protein (RefSeq) compare
b0018 mokC -0.6 -1.1 regulatory protein for HokC, overlaps CDS of hokC (NCBI) compare
b1438 ydcQ -0.6 -1.4 predicted DNA-binding transcriptional regulator (RefSeq) compare
b0163 yaeH -0.6 -2.6 hypothetical protein (NCBI) compare
b2343 b2343 -0.6 -1.0 orf, hypothetical protein (VIMSS) compare
b2221 atoD -0.6 -1.8 acetyl-CoA:acetoacetyl-CoA transferase, alpha subunit (NCBI) compare
b2280 nuoJ -0.6 -2.6 NADH dehydrogenase subunit J (NCBI) compare
b1877 yecT -0.6 -1.2 orf, hypothetical protein (VIMSS) compare
b1690 ydiM -0.6 -1.1 predicted transporter (NCBI) compare
b0888 trxB -0.6 -1.8 thioredoxin reductase, FAD/NAD(P)-binding (NCBI) compare
b1105 ycfM -0.6 -2.4 predicted outer membrane lipoprotein (NCBI) compare
b4414 tff -0.6 -1.6 unknown RNA (NCBI) compare
b1074 flgC -0.6 -1.8 flagellar basal-body rod protein C (NCBI) compare
b1727 yniC -0.6 -1.6 predicted hydrolase (NCBI) compare
b1739 osmE -0.6 -1.1 DNA-binding transcriptional activator (NCBI) compare
b3741 gidA -0.6 -1.7 glucose-inhibited division protein A (NCBI) compare
b2277 nuoM -0.6 -2.7 NADH dehydrogenase subunit M (NCBI) compare
b2518 ndk -0.6 -1.2 nucleoside diphosphate kinase (NCBI) compare
b3636 rpmG -0.6 -0.8 50S ribosomal protein L33 (NCBI) compare
b4242 mgtA -0.6 -3.9 magnesium transporter (NCBI) compare
b4520 ymgF -0.6 -0.9 hypothetical protein (NCBI) compare
b2540 hcaC -0.6 -2.0 3-phenylpropionate dioxygenase, predicted ferredoxin subunit (NCBI) compare
b1279 yciS -0.6 -0.9 conserved inner membrane protein (NCBI) compare
b4163 glyV -0.6 -1.2 tRNA-Gly (NCBI) compare
b1426 ydcH -0.6 -1.1 orf, hypothetical protein (VIMSS) compare
b3398 yrfF -0.6 -2.0 predicted inner membrane protein (NCBI) compare
b2962 yggX -0.5 -1.9 hypothetical protein (NCBI) compare
b2895 fldB -0.5 -1.9 flavodoxin 2 (NCBI) compare
b3469 zntA -0.5 -3.3 zinc, cobalt and lead efflux system (NCBI) compare
b0125 hpt -0.5 -2.5 hypoxanthine phosphoribosyltransferase (VIMSS) compare
b2642 yfjW -0.5 -0.7 CP4-57 prophage; predicted inner membrane protein (NCBI) compare
b1762 b1762 -0.5 -1.2 orf, hypothetical protein (VIMSS) compare
b1337 abgB -0.5 -1.8 predicted peptidase, aminobenzoyl-glutamate utilization protein (NCBI) compare
b3889 yiiE -0.5 -1.0 predicted transcriptional regulator (RefSeq) compare
b4435 isrC -0.5 -1.4 unknown RNA (NCBI) compare
b3157 yhbT -0.5 -2.2 predicted lipid carrier protein (NCBI) compare
b4451 ryhB -0.5 -0.9 Regulatory sRNA mediating positive Fur regulon response; requires Hfq for function; global iron regulator; degraded by RNase E when bound to target (RefSeq) compare
b1765 ydjA -0.5 -0.6 predicted oxidoreductase (NCBI) compare
b4179 vacB -0.5 -2.6 putative enzyme (VIMSS) compare
b1344 ydaO -0.5 -1.9 predicted C32 tRNA thiolase (NCBI) compare
b2567 rnc -0.5 -0.3 ribonuclease III (NCBI) compare
b1773 ydjI -0.5 -1.1 predicted aldolase (NCBI) compare
b4509 ylcG -0.5 -1.3 DLP12 prophage; predicted protein (NCBI) compare
b3500 gor -0.5 -0.9 glutathione reductase (NCBI) compare
b0676 nagC -0.5 -2.8 DNA-binding transcriptional dual regulator, repressor of N-acetylglucosamine (NCBI) compare
b1465 narV -0.5 -1.5 nitrate reductase 2 (NRZ), gamma subunit (NCBI) compare
b0889 lrp -0.5 -1.4 DNA-binding transcriptional dual regulator, leucine-binding (NCBI) compare
b4686 yshB -0.5 -1.3 expressed protein (RefSeq) compare
b3726 pstA -0.5 -2.1 phosphate transporter subunit (NCBI) compare
b1236 galU -0.5 -1.9 glucose-1-phosphate uridylyltransferase (NCBI) compare
b0506 allR -0.5 -2.5 DNA-binding transcriptional repressor (NCBI) compare
b1185 dsbB -0.5 -1.6 reoxidizes DsbA protein following formation of disulfide bond in P-ring of flagella. (VIMSS) compare
b4614 sokA -0.5 -1.3 no description compare
b3620 rfaF -0.5 -2.1 ADP-heptose:LPS heptosyltransferase II (NCBI) compare
b1442 ydcU -0.5 -1.8 predicted spermidine/putrescine transporter subunit (NCBI) compare
b4497 yeeL -0.5 -0.6 no description compare
b0053 surA -0.5 -2.4 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b2912 ygfA -0.5 -1.6 putative ligase (VIMSS) compare
b1735 chbR -0.5 -1.4 DNA-binding transcriptional dual regulator (NCBI) compare
b2017 yefM -0.5 -1.0 orf, hypothetical protein (VIMSS) compare
b0783 moaC -0.5 -2.5 molybdenum cofactor biosynthesis protein C (NCBI) compare
b2707 srlR -0.5 -2.2 DNA-bindng transcriptional repressor (NCBI) compare
b0509 glxR -0.5 -2.7 tartronate semialdehyde reductase, NADH-dependent (NCBI) compare
b4618 tisB -0.5 -1.6 lexA-regulated toxic peptide (RefSeq) compare
b1969 yedW -0.5 -1.8 putative 2-component transcriptional regulator (VIMSS) compare
b1143 ymfI -0.5 -0.7 orf, hypothetical protein (VIMSS) compare
b1692 ydiB -0.5 -1.3 quinate/shikimate 5-dehydrogenase, NAD(P)-binding (NCBI) compare
b1130 phoP -0.5 -0.3 DNA-binding response regulator in two-component regulatory system with PhoQ (NCBI) compare
b4178 yjeB -0.5 -1.9 predicted DNA-binding transcriptional regulator (NCBI) compare
b3348 slyX -0.5 -2.0 hypothetical protein (NCBI) compare
b0990 cspG -0.5 -0.5 DNA-binding transcriptional regulator (NCBI) compare
b4048 yjbM -0.5 -0.3 hypothetical protein (NCBI) compare
b0677 nagA -0.5 -2.4 N-acetylglucosamine-6-phosphate deacetylase (NCBI) compare
b0460 hha -0.5 -1.9 modulator of gene expression, with H-NS (NCBI) compare
b1306 pspC -0.5 -1.8 DNA-binding transcriptional activator (NCBI) compare
b4502 yeiW -0.5 -2.1 hypothetical protein (NCBI) compare
b1258 yciF -0.5 -0.4 hypothetical protein (NCBI) compare
b4481 rffT -0.5 -2.5 4-alpha-L-fucosyltransferase (NCBI) compare
b1647 ydhF -0.5 -1.7 predicted oxidoreductase (NCBI) compare
b3631 rfaG -0.5 -3.6 glucosyltransferase I (NCBI) compare
b3393 yrfB -0.5 -2.4 hypothetical protein (NCBI) compare
b1600 mdtJ -0.5 -0.8 multidrug efflux system transporter (NCBI) compare
b2790 yqcA -0.5 -1.8 flavodoxin (NCBI) compare
b0289 yagV -0.5 -2.0 orf, hypothetical protein (VIMSS) compare
b3205 yhbJ -0.5 -1.9 hypothetical protein (NCBI) compare
b2168 fruK -0.5 -0.7 1-phosphofructokinase (NCBI) compare
b1063 yceB -0.5 -1.3 predicted lipoprotein (NCBI) compare
b1248 b1248 -0.4 -1.6 orf, hypothetical protein (VIMSS) compare
b4546 ypeB -0.4 -0.8 hypothetical protein (NCBI) compare
b2698 recX -0.4 -1.3 RecA regulator RecX (NCBI) compare
b1563 relE -0.4 -0.6 Qin prophage; toxin of the RelE-RelB toxin-antitoxin system (NCBI) compare
b4191 ulaR -0.4 -1.5 DNA-binding transcriptional dual regulator (NCBI) compare
b1676 pykF -0.4 -1.4 pyruvate kinase (NCBI) compare
b1217 chaB -0.4 -0.7 cation transport regulator (NCBI) compare
b2263 yfbB -0.4 -1.1 predicted peptidase (NCBI) compare
b0890 ftsK -0.4 -1.4 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b3131 agaR -0.4 -1.8 DNA-binding transcriptional dual regulator (NCBI) compare
b1165 ymgA -0.4 -0.3 hypothetical protein (NCBI) compare
b3100 yqjK -0.4 -1.6 hypothetical protein (NCBI) compare
b2127 mlrA -0.4 -2.3 DNA-binding transcriptional regulator (NCBI) compare
b4408 csrB -0.4 -1.6 CsrA-binding sRNA, antagonizing CsrA regulation (NCBI) compare
b3658 selC -0.4 -1.0 tRNA-Sec (NCBI) compare
b1963 b1963 -0.4 -1.2 orf, hypothetical protein (VIMSS) compare
b1734 chbF -0.4 -2.3 cryptic phospho-beta-glucosidase, NAD(P)-binding (NCBI) compare
b2699 recA -0.4 -0.4 recombinase A (NCBI) compare
b1777 b1777 -0.4 -1.4 orf, hypothetical protein (VIMSS) compare
b4243 yjgF -0.4 -2.1 orf, hypothetical protein (VIMSS) compare
b4196 ulaD -0.4 -2.3 3-keto-L-gulonate 6-phosphate decarboxylase (NCBI) compare
b2198 ccmD -0.4 -1.4 cytochrome c biogenesis protein (NCBI) compare
b2674 nrdI -0.4 -1.4 hypothetical protein (NCBI) compare
b2301 yfcF -0.4 -1.8 predicted enzyme (NCBI) compare
b2840 ygeA -0.4 -2.3 predicted racemase (NCBI) compare
b4590 ybfK -0.4 -0.3 hypothetical protein (RefSeq) compare
b0080 fruR -0.4 -2.1 DNA-binding transcriptional dual regulator (NCBI) compare
b0014 dnaK -0.4 -0.8 molecular chaperone DnaK (NCBI) compare
b2734 pphB -0.4 -1.4 serine/threonine-specific protein phosphatase 2 (NCBI) compare
b3493 pitA -0.4 -2.3 phosphate transporter, low-affinity (NCBI) compare
b3962 udhA -0.4 -2.2 putative oxidoreductase (VIMSS) compare
b2859 ygeO -0.4 -0.7 hypothetical protein (RefSeq) compare
b1305 pspB -0.4 -0.9 phage shock protein B (NCBI) compare
b4215 ytfI -0.4 -0.7 hypothetical protein (NCBI) compare
b0953 rmf -0.4 -1.3 ribosome modulation factor (NCBI) compare


Specific Phenotypes

None in this experiment

For Escherichia coli BW25113 in phage experiments

For phage Phage need info across organisms