Experiment set12IT031 for Escherichia coli BW25113

Compare to:

LB

200 most important genes:

  gene name fitness t score description  
b1290 sapF -1.8 -2.3 predicted antimicrobial peptide transporter subunit (NCBI) compare
b3183 obgE -1.8 -1.6 GTPase involved in cell partioning and DNA repair (NCBI) compare
b1865 nudB -1.7 -2.2 dATP pyrophosphohydrolase (NCBI) compare
b2934 cmtB -1.7 -1.1 predicted mannitol-specific enzyme IIA component of PTS (NCBI) compare
b1863 ruvC -1.7 -2.6 Holliday junction resolvase (NCBI) compare
b0049 apaH -1.6 -3.4 diadenosinetetraphosphatase (NCBI) compare
b3979 thrT -1.5 -0.7 tRNA-Thr (NCBI) compare
b1291 sapD -1.2 -2.1 predicted antimicrobial peptide transporter subunit (NCBI) compare
b3863 polA -1.2 -0.8 DNA polymerase I (NCBI) compare
b2168 fruK -1.2 -1.1 1-phosphofructokinase (NCBI) compare
b0739 tolA -1.2 -2.8 cell envelope integrity inner membrane protein TolA (NCBI) compare
b4655 ythA -1.2 -1.8 expressed protein (RefSeq) compare
b0200 gmhB -1.2 -1.5 hypothetical protein (NCBI) compare
b2330 yfcB -1.1 -1.6 putative adenine-specific methylase (VIMSS) compare
b3261 fis -1.1 -1.6 DNA-binding protein Fis (NCBI) compare
b0149 mrcB -1.1 -8.1 penicillin-binding protein 1b (NCBI) compare
b1361 ydaW -1.1 -0.7 orf, hypothetical protein (VIMSS) compare
b4603 rseX -1.1 -0.9 sRNA regulating ompA and ompC translation, with Hfq (RefSeq) compare
b2279 nuoK -1.1 -2.1 NADH dehydrogenase subunit K (NCBI) compare
b0542 renD -1.0 -2.2 orf, hypothetical protein (VIMSS) compare
b1293 sapB -1.0 -1.2 predicted antimicrobial peptide transporter subunit (NCBI) compare
b1429 tehA -1.0 -1.3 potassium-tellurite ethidium and proflavin transporter (NCBI) compare
b0386 proC -1.0 -3.8 pyrroline-5-carboxylate reductase (NCBI) compare
b0740 tolB -1.0 -3.4 translocation protein TolB precursor (NCBI) compare
b2939 yqgB -1.0 -2.1 predicted protein (RefSeq) compare
b2498 upp -1.0 -2.4 uracil phosphoribosyltransferase (VIMSS) compare
b0726 sucA -1.0 -2.9 alpha-ketoglutarate decarboxylase (NCBI) compare
b3613 yibP -1.0 -2.8 putative membrane protein (VIMSS) compare
b3916 pfkA -1.0 -1.7 6-phosphofructokinase (NCBI) compare
b0741 pal -0.9 -2.6 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b4375 prfC -0.9 -2.9 peptide chain release factor 3 (NCBI) compare
b4676 yoaK -0.9 -0.9 expressed protein (RefSeq) compare
b4146 yjeK -0.9 -1.6 predicted lysine aminomutase (NCBI) compare
b2808 gcvA -0.8 -2.7 DNA-binding transcriptional dual regulator (NCBI) compare
b1236 galU -0.8 -3.0 glucose-1-phosphate uridylyltransferase (NCBI) compare
b1882 cheY -0.8 -0.7 chemotaxis regulator transmitting signal to flagellar motor component (NCBI) compare
b4513 kdpF -0.8 -2.5 potassium ion accessory transporter subunit (NCBI) compare
b2288 nuoA -0.8 -2.0 NADH dehydrogenase I chain A (VIMSS) compare
b1677 lpp -0.8 -1.2 murein lipoprotein (NCBI) compare
b3962 udhA -0.8 -4.3 putative oxidoreductase (VIMSS) compare
b1727 yniC -0.8 -2.5 predicted hydrolase (NCBI) compare
b0730 mngR -0.8 -1.1 DNA-binding transcriptional dual regulator, fatty-acyl-binding (NCBI) compare
b3021 ygiT -0.8 -2.1 predicted DNA-binding transcriptional regulator (NCBI) compare
b0912 ihfB -0.8 -3.0 integration host factor subunit beta (NCBI) compare
b4438 cyaR -0.8 -2.4 sRNA effector of ompX mRNA instability, cAMP-induced; hfq-dependent (RefSeq) compare
b3706 trmE -0.8 -2.7 tRNA modification GTPase (NCBI) compare
b2650 ypjC -0.8 -0.5 hypothetical protein (RefSeq) compare
b1712 ihfA -0.8 -1.1 integration host factor subunit alpha (NCBI) compare
b1575 dicB -0.8 -1.3 Qin prophage; cell division inhibition protein (NCBI) compare
b0167 glnD -0.8 -3.0 PII uridylyl-transferase (NCBI) compare
b0888 trxB -0.7 -2.5 thioredoxin reductase, FAD/NAD(P)-binding (NCBI) compare
b1258 yciF -0.7 -0.5 hypothetical protein (NCBI) compare
b0738 tolR -0.7 -1.6 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b4520 ymgF -0.7 -1.2 hypothetical protein (NCBI) compare
b0502 ylbG -0.7 -2.2 no description compare
b0990 cspG -0.7 -0.6 DNA-binding transcriptional regulator (NCBI) compare
b3741 gidA -0.7 -2.3 glucose-inhibited division protein A (NCBI) compare
b1286 rnb -0.7 -1.5 exoribonuclease II (NCBI) compare
b0018 mokC -0.7 -1.2 regulatory protein for HokC, overlaps CDS of hokC (NCBI) compare
b2576 srmB -0.7 -2.0 ATP-dependent RNA helicase (NCBI) compare
b3500 gor -0.7 -1.2 glutathione reductase (NCBI) compare
b1195 ymgE -0.7 -2.2 predicted inner membrane protein (NCBI) compare
b3098 yqjD -0.7 -1.5 hypothetical protein (NCBI) compare
b0688 pgm -0.7 -2.0 phosphoglucomutase (NCBI) compare
b2280 nuoJ -0.7 -3.0 NADH dehydrogenase subunit J (NCBI) compare
b3493 pitA -0.7 -3.7 phosphate transporter, low-affinity (NCBI) compare
b2286 nuoC -0.6 -3.0 NADH:ubiquinone oxidoreductase, chain C,D (RefSeq) compare
b1842 holE -0.6 -1.5 DNA polymerase III, theta subunit (NCBI) compare
b3649 rpoZ -0.6 -1.9 DNA-directed RNA polymerase subunit omega (NCBI) compare
b2017 yefM -0.6 -1.6 orf, hypothetical protein (VIMSS) compare
b0530 sfmA -0.6 -1.7 putative fimbrial-like protein (VIMSS) compare
b0460 hha -0.6 -2.5 modulator of gene expression, with H-NS (NCBI) compare
b1185 dsbB -0.6 -1.9 reoxidizes DsbA protein following formation of disulfide bond in P-ring of flagella. (VIMSS) compare
b1192 ldcA -0.6 -2.5 L,D-carboxypeptidase A (NCBI) compare
b2276 nuoN -0.6 -2.6 NADH:ubiquinone oxidoreductase, membrane subunit N (RefSeq) compare
b0238 gpt -0.6 -2.3 xanthine phosphoribosyltransferase (NCBI) compare
b0729 sucD -0.6 -2.1 succinyl-CoA synthetase subunit alpha (NCBI) compare
b4458 oxyS -0.6 -1.0 global regulatory RNA (NCBI) compare
b3002 yqhA -0.6 -0.8 hypothetical protein (NCBI) compare
b1090 plsX -0.6 -2.9 glycerolphosphate auxotrophy in plsB background (VIMSS) compare
b4460 araH -0.6 -2.0 fused L-arabinose transporter subunits of ABC superfamily: membrane components (RefSeq) compare
b2281 nuoI -0.6 -1.7 NADH dehydrogenase subunit I (NCBI) compare
b2343 b2343 -0.6 -1.0 orf, hypothetical protein (VIMSS) compare
b2278 nuoL -0.6 -3.7 NADH dehydrogenase subunit L (NCBI) compare
b0247 ykfG -0.6 -0.9 CP4-6 prophage; predicted DNA repair protein (NCBI) compare
b0101 yacG -0.6 -1.3 zinc-binding protein (NCBI) compare
b0836 yliH -0.6 -1.7 hypothetical protein (NCBI) compare
b4242 mgtA -0.6 -3.9 magnesium transporter (NCBI) compare
b4685 yrbN -0.6 -1.3 expressed protein (RefSeq) compare
b1362 rzpR -0.6 -1.4 putative Rac prophage endopeptidase (VIMSS) compare
b2277 nuoM -0.6 -2.6 NADH dehydrogenase subunit M (NCBI) compare
b4194 ulaB -0.6 -2.0 L-ascorbate-specific enzyme IIB component of PTS (NCBI) compare
b3545 proK -0.6 -1.4 tRNA-Pro (NCBI) compare
b3806 cyaA -0.5 -2.2 adenylate cyclase (NCBI) compare
b4546 ypeB -0.5 -1.0 hypothetical protein (NCBI) compare
b1179 ycgL -0.5 -1.6 conserved protein (NCBI) compare
b1877 yecT -0.5 -1.2 orf, hypothetical protein (VIMSS) compare
b0605 ahpC -0.5 -1.9 alkyl hydroperoxide reductase, C22 subunit (NCBI) compare
b1550 b1550 -0.5 -0.9 orf, hypothetical protein (VIMSS) compare
b2859 ygeO -0.5 -1.0 hypothetical protein (RefSeq) compare
b4570 lomR -0.5 -1.2 no description compare
b3071 yqjI -0.5 -2.0 predicted transcriptional regulator (NCBI) compare
b1693 aroD -0.5 -2.5 3-dehydroquinate dehydratase (NCBI) compare
b1248 b1248 -0.5 -1.8 orf, hypothetical protein (VIMSS) compare
b1434 ydcN -0.5 -1.2 predicted DNA-binding transcriptional regulator (NCBI) compare
b2912 ygfA -0.5 -1.7 putative ligase (VIMSS) compare
b2283 nuoG -0.5 -2.9 NADH:ubiquinone oxidoreductase, chain G (RefSeq) compare
b3101 yqjF -0.5 -1.6 orf, hypothetical protein (VIMSS) compare
b1368 ynaA -0.5 -1.4 Rac prophage; predicted tail protein (RefSeq) compare
b4041 plsB -0.5 -1.2 glycerol-3-phosphate acyltransferase (VIMSS) compare
b1109 ndh -0.5 -2.2 respiratory NADH dehydrogenase 2/cupric reductase (NCBI) compare
b2567 rnc -0.5 -0.3 ribonuclease III (NCBI) compare
b4702 mgtL -0.5 -1.0 regulatory leader peptide for mgtA (NCBI) compare
b3398 yrfF -0.5 -1.8 predicted inner membrane protein (NCBI) compare
b4179 vacB -0.5 -2.6 putative enzyme (VIMSS) compare
b4410 ecnA -0.5 -1.0 entericidin A membrane lipoprotein, antidote entericidin B (NCBI) compare
b1217 chaB -0.5 -0.7 cation transport regulator (NCBI) compare
b1762 b1762 -0.5 -1.2 orf, hypothetical protein (VIMSS) compare
b2448 yffQ -0.5 -1.8 CPZ-55 prophage; predicted protein (RefSeq) compare
b1155 ymfS -0.5 -2.3 e14 prophage; predicted protein (NCBI) compare
b0630 lipB -0.5 -0.7 protein of lipoate biosynthesis (VIMSS) compare
b2846 yqeH -0.5 -0.3 orf, hypothetical protein (VIMSS) compare
b2553 glnB -0.5 -2.3 regulatory protein P-II for glutamine synthetase (NCBI) compare
b3842 rfaH -0.5 -2.2 transcriptional activator RfaH (NCBI) compare
b1871 yecP -0.5 -1.8 predicted S-adenosyl-L-methionine-dependent methyltransferase (NCBI) compare
b2894 xerD -0.5 -0.6 site-specific tyrosine recombinase XerD (NCBI) compare
b1855 lpxM -0.5 -2.2 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase (NCBI) compare
b0764 modB -0.5 -2.1 molybdate ABC transporter permease protein (NCBI) compare
b1520 b1520 -0.5 -1.4 orf, hypothetical protein (VIMSS) compare
b3890 yiiF -0.5 -1.5 orf, hypothetical protein (VIMSS) compare
b4451 ryhB -0.5 -1.0 Regulatory sRNA mediating positive Fur regulon response; requires Hfq for function; global iron regulator; degraded by RNase E when bound to target (RefSeq) compare
b0430 cyoC -0.5 -2.3 cytochrome o ubiquinol oxidase subunit III (NCBI) compare
b4406 yaeP -0.5 -1.2 hypothetical protein (NCBI) compare
b1890 motA -0.5 -1.2 flagellar motor protein MotA (NCBI) compare
b2376 ypdI -0.5 -1.4 predicted lipoprotein involved in colanic acid biosynthesis (NCBI) compare
b3616 tdh -0.5 -2.4 L-threonine 3-dehydrogenase (NCBI) compare
b4163 glyV -0.5 -0.9 tRNA-Gly (NCBI) compare
b2104 thiM -0.4 -2.0 hydroxyethylthiazole kinase (NCBI) compare
b4373 rimI -0.4 -1.5 ribosomal-protein-alanine N-acetyltransferase (NCBI) compare
b1506 yneL -0.4 -0.8 predicted transcriptional regulator (NCBI) compare
b1580 rspB -0.4 -2.2 predicted oxidoreductase, Zn-dependent and NAD(P)-binding (NCBI) compare
b4501 torI -0.4 -1.9 response regulator inhibitor for tor operon (NCBI) compare
b1690 ydiM -0.4 -1.0 predicted transporter (NCBI) compare
b2804 fucU -0.4 -1.4 L-fucose mutarotase (NCBI) compare
b1083 flgL -0.4 -1.7 flagellar hook-associated protein L (NCBI) compare
b3437 gntK -0.4 -2.5 gluconokinase 2, thermoresistant (VIMSS) compare
b2513 yfgM -0.4 -2.0 hypothetical protein (NCBI) compare
b0125 hpt -0.4 -2.0 hypoxanthine phosphoribosyltransferase (VIMSS) compare
b1860 ruvB -0.4 -0.4 Holliday junction DNA helicase B (NCBI) compare
b2518 ndk -0.4 -1.2 nucleoside diphosphate kinase (NCBI) compare
b1304 pspA -0.4 -1.5 regulatory protein for phage-shock-protein operon (NCBI) compare
b4243 yjgF -0.4 -2.4 orf, hypothetical protein (VIMSS) compare
b1524 yneH -0.4 -0.6 predicted glutaminase (NCBI) compare
b0406 tgt -0.4 -2.2 queuine tRNA-ribosyltransferase (NCBI) compare
b4701 sokX -0.4 -0.4 sok-related sRNA, function unknown (RefSeq) compare
b1279 yciS -0.4 -0.6 conserved inner membrane protein (NCBI) compare
b0789 ybhO -0.4 -2.3 cardiolipin synthase 2 (NCBI) compare
b0503 ybbB -0.4 -2.1 tRNA 2-selenouridine synthase, selenophosphate-dependent (NCBI) compare
b0504 ybbS -0.4 -1.8 DNA-binding transcriptional activator of the allD operon (NCBI) compare
b0965 b0965 -0.4 -1.2 orf, hypothetical protein (VIMSS) compare
b0780 ybhK -0.4 -1.8 predicted transferase with NAD(P)-binding Rossmann-fold domain (NCBI) compare
b0161 degP -0.4 -2.5 serine endoprotease (protease Do), membrane-associated (NCBI) compare
b0437 clpP -0.4 -2.1 ATP-dependent Clp protease proteolytic subunit (NCBI) compare
b0953 rmf -0.4 -1.1 ribosome modulation factor (NCBI) compare
b1778 yeaA -0.4 -1.3 methionine sulfoxide reductase B (NCBI) compare
b4191 ulaR -0.4 -1.5 DNA-binding transcriptional dual regulator (NCBI) compare
b3469 zntA -0.4 -2.5 zinc, cobalt and lead efflux system (NCBI) compare
b3205 yhbJ -0.4 -1.6 hypothetical protein (NCBI) compare
b0676 nagC -0.4 -2.6 DNA-binding transcriptional dual regulator, repressor of N-acetylglucosamine (NCBI) compare
b1553 ydfP -0.4 -0.8 Qin prophage; conserved protein (NCBI) compare
b0683 fur -0.4 -0.5 ferric uptake regulator (NCBI) compare
b0696 kdpC -0.4 -1.2 potassium-transporting ATPase subunit C (NCBI) compare
b3378 yhfU -0.4 -1.4 orf, hypothetical protein (VIMSS) compare
b2528 iscA -0.4 -0.8 iron-sulfur cluster assembly protein (NCBI) compare
b1533 ydeD -0.4 -1.1 orf, hypothetical protein (VIMSS) compare
b3169 nusA -0.4 -1.3 transcription elongation factor NusA (NCBI) compare
b1884 cheR -0.4 -2.0 chemotaxis regulator, protein-glutamate methyltransferase (NCBI) compare
b2163 yeiL -0.4 -1.9 putative transcriptional regulator (VIMSS) compare
b4202 rpsR -0.4 -0.5 30S ribosomal protein S18 (NCBI) compare
b3778 rep -0.4 -2.4 DNA helicase and single-stranded DNA-dependent ATPase (NCBI) compare
b4505 insX -0.4 -0.5 predicted IS protein (RefSeq) compare
b4445 omrB -0.4 -1.1 sRNA down regulates OM proteins; positively regulated by OmpR/EnvZ; binds Hfq (RefSeq) compare
b2637 yfjT -0.4 -1.0 CP4-57 prophage; predicted protein (NCBI) compare
b4535 yniD -0.4 -0.5 predicted protein (RefSeq) compare
b1686 ydiI -0.4 -0.8 hypothetical protein (NCBI) compare
b1603 pntA -0.4 -1.6 NAD(P) transhydrogenase subunit alpha (NCBI) compare
b1261 trpB -0.4 -0.9 tryptophan synthase subunit beta (NCBI) compare
b2434 b2434 -0.4 -1.4 orf, hypothetical protein (VIMSS) compare
b1634 tppB -0.4 -1.9 putative tripeptide transporter permease (NCBI) compare
b2435 amiA -0.4 -1.5 N-acetylmuramoyl-l-alanine amidase I (NCBI) compare
b0310 ykgH -0.4 -0.5 predicted inner membrane protein (NCBI) compare
b0722 sdhD -0.4 -1.7 succinate dehydrogenase cytochrome b556 small membrane subunit (NCBI) compare
b3601 mtlR -0.4 -2.3 DNA-binding repressor (NCBI) compare
b3075 ebgR -0.4 -2.0 DNA-binding transcriptional repressor (NCBI) compare
b1285 gmr -0.4 -2.0 modulator of Rnase II stability (NCBI) compare
b3094 exuR -0.4 -1.9 negative regulator of exu regulon, exuT, uxaAC, and uxuB (VIMSS) compare
b3250 mreC -0.4 -0.9 cell wall structural complex MreBCD transmembrane component MreC (NCBI) compare
b3726 pstA -0.4 -1.5 phosphate transporter subunit (NCBI) compare
b1235 rssB -0.4 -2.2 response regulator of RpoS (NCBI) compare
b1735 chbR -0.4 -1.1 DNA-binding transcriptional dual regulator (NCBI) compare


Specific Phenotypes

None in this experiment

For Escherichia coli BW25113 in lb experiments