Experiment set12IT029 for Pseudomonas putida KT2440

Compare to:

Phenylacetic acid carbon source

200 most important genes:

  gene name fitness t score description  
PP_4890 -8.1 -5.6 ATP phosphoribosyltransferase regulatory subunit compare
PP_4364 -8.0 -5.5 putative Anti-sigma F factor antagonist compare
PP_0787 -7.5 -5.2 quinolinate phosphoribosyltransferase (decarboxylating) monomer compare
PP_3511 -7.4 -7.2 Branched-chain-amino-acid aminotransferase compare
PP_2001 -7.2 -8.6 O-succinylhomoserine sulfhydrylase compare
PP_1988 -7.2 -8.5 3-isopropylmalate dehydrogenase compare
PP_0420 -7.1 -10.9 aminodeoxychorismate synthase / para-aminobenzoate synthase multi-enzyme complex compare
PP_4679 -7.1 -4.9 acetohydroxybutanoate synthase / acetolactate synthase compare
PP_1985 -7.1 -6.9 3-isopropylmalate dehydratase large subunit compare
PP_0422 -7.0 -6.9 Indole-3-glycerol phosphate synthase compare
PP_4680 -6.9 -11.5 acetohydroxybutanoate synthase / acetolactate synthase compare
PP_5097 -6.8 -12.2 homoserine O-acetyltransferase compare
PP_0966 -6.7 -11.3 Histidinol dehydrogenase compare
PP_5098 -6.6 -7.9 methionine biosynthesis protein MetW compare
PP_0164 -6.5 -4.5 conserved protein of unknown function compare
PP_1986 -6.5 -4.5 3-isopropylmalate dehydratase small subunit compare
PP_1995 -6.5 -4.5 N-(5'-phosphoribosyl)anthranilate isomerase compare
PP_0967 -6.5 -12.5 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
PP_4678 -6.4 -16.6 Ketol-acid reductoisomerase compare
PP_5014 -6.4 -4.4 Phosphoribosyl-AMP cyclohydrolase compare
PP_0290 -6.3 -4.4 Imidazole glycerol phosphate synthase subunit HisH compare
PP_4724 -6.3 -4.4 Carbamoyl-phosphate synthase small chain compare
PP_5185 -6.2 -4.3 acetylglutamate kinase-like protein (regulatory domain)/amino acid N-acetyltransferase compare
PP_0417 -6.2 -21.3 Anthranilate synthase component 1 compare
PP_4723 -6.2 -4.3 Carbamoyl-phosphate synthase large chain compare
PP_2371 -6.2 -8.4 Sulphite reductase hemoprotein, beta subunit compare
PP_0965 -6.1 -12.4 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
PP_5015 -6.1 -6.0 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
PP_0691 -6.0 -4.2 Glutamate 5-kinase compare
PP_1088 -6.0 -4.2 Argininosuccinate synthase compare
PP_2168 -5.9 -10.7 Transaldolase compare
PP_1231 -5.7 -7.8 quinolinate synthase [4Fe-4S] cluster subunit compare
PP_0293 -5.6 -3.9 Imidazole glycerol phosphate synthase subunit HisF compare
PP_5289 -5.5 -5.4 Acetylglutamate kinase compare
PP_3277 -5.2 -5.7 ring 1,2-phenylacetyl-CoA epoxidase regulatory subunit compare
PP_4909 -5.2 -10.5 phosphoserine phosphatase compare
PP_1025 -5.1 -12.8 2-isopropylmalate synthase compare
PP_3999 -5.0 -7.7 Uroporphyrinogen-III C-methyltransferase/Precorrin-2 dehydrogenase/Sirohydrochlorin ferrochelatase compare
PP_2327 -5.0 -6.8 transcriptional dual regulator / CysB-O-acetyl-L-serine compare
PP_0083 -4.9 -4.8 tryptophan synthase beta chain compare
PP_5128 -4.9 -8.5 Dihydroxy-acid dehydratase compare
PP_3270 -4.8 -13.5 oxepin-CoA hydrolase/3-oxo-5,6-dehydrosuberyl-CoA semialdehyde dehydrogenase conserved
PP_3283 -4.8 -6.8 1,2-epoxyphenylacetyl-CoA isomerase conserved
PP_0421 -4.8 -8.4 Anthranilate phosphoribosyltransferase compare
PP_3279 -4.8 -12.6 phenylacetate-CoA ligase conserved
PP_0184 -4.8 -3.3 Argininosuccinate lyase compare
PP_3284 -4.7 -5.3 enoyl-CoA hydratase-isomerase conserved
PP_3285 -4.6 -7.4 detoxifying thioesterase of the phenylacetate degradation pathway compare
PP_0289 -4.6 -8.5 Imidazoleglycerol-phosphate dehydratase compare
PP_0292 -4.5 -4.8 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
PP_3276 -4.5 -7.5 ring 1,2-phenylacetyl-CoA epoxidase beta subunit conserved
PP_3282 -4.5 -12.0 3-hydroxyadipyl-CoA dehydrogenase conserved
PP_5095 -4.4 -3.0 pyrroline-5-carboxylate reductase compare
PP_4799 -4.4 -3.0 putative Muramoyltetrapeptide carboxypeptidase compare
PP_0082 -4.4 -5.2 tryptophan synthase alpha chain compare
PP_4999 -4.3 -2.9 dihydroorotase-like protein compare
PP_4699 -4.2 -4.1 3-methyl-2-oxobutanoate hydroxymethyltransferase compare
PP_3274 -4.2 -11.2 ring 1,2-phenylacetyl-CoA epoxidase, reductase subunit conserved
PP_5155 -3.9 -4.8 D-3-phosphoglycerate dehydrogenase / alpha-ketoglutarate reductase compare
PP_3280 -3.7 -5.5 3-oxoadipyl-CoA/3-oxo-5,6-dehydrosuberyl-CoA thiolase conserved
PP_4122 -3.7 -3.6 proton-pumping NADH:ubiquinone oxidoreductase, respiratory complex I, subunit E compare
PP_5303 -3.5 -7.9 aminoacrylate/iminopropionate hydrolase/deaminase compare
PP_3278 -3.5 -5.7 ring 1,2-phenylacetyl-CoA epoxidase alpha subunit conserved
PP_3494 -3.5 -8.9 conserved exported protein of unknown function compare
PP_2388 -3.5 -5.4 Transporter, LysE family compare
PP_3273 -3.5 -5.8 conserved protein of unknown function compare
PP_3272 -3.5 -10.1 acetate permease compare
PP_1215 -3.4 -2.3 Crossover junction endodeoxyribonuclease RuvC compare
PP_2370 -3.4 -3.1 conserved protein of unknown function compare
PP_1079 -3.4 -6.2 Ornithine carbamoyltransferase compare
PP_1237 -3.3 -2.1 4-hydroxy-tetrahydrodipicolinate synthase compare
PP_0356 -3.3 -6.2 malate synthase G compare
PP_4696 -3.2 -4.9 Nitrogen regulation protein NR(I) compare
PP_2328 -3.2 -8.0 Phosphoadenosine phosphosulfate reductase compare
PP_0291 -3.2 -3.1 conserved protein of unknown function compare
PP_4058 -3.1 -12.1 1,4-alpha-glucan branching enzyme compare
PP_1355 -3.0 -17.3 Muropeptide permease AmpG compare
PP_2145 -3.0 -9.7 beta-N-acetylglucosaminidase compare
PP_0393 -2.9 -2.0 putative 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase compare
PP_0406 -2.9 -5.3 Nucleotidyltransferase family protein compare
PP_1764 -2.8 -5.1 Phosphoglycolate phosphatase 2 compare
PP_4700 -2.8 -1.9 pantothenate synthetase compare
PP_0405 -2.8 -14.8 conserved protein of unknown function compare
PP_5035 -2.8 -7.4 Histidine utilization repressor compare
PP_5104 -2.8 -8.3 thiazole synthase compare
PP_2390 -2.7 -6.0 Transcriptional regulator, LysR family compare
PP_1233 -2.7 -5.3 sulfurtransferase compare
PP_0434 -2.7 -8.1 Anhydro-N-acetylmuramic acid kinase compare
PP_3493 -2.7 -9.7 Transcriptional regulator, LysR family compare
PP_1468 -2.7 -2.2 Tyrosine recombinase XerD compare
PP_0339 -2.6 -6.5 Pyruvate dehydrogenase E1 component compare
PP_2356 -2.6 -10.5 putative Phytochrome family protein compare
PP_2136 -2.5 -6.0 enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase compare
PP_3790 -2.5 -6.1 diaminopimelate epimerase compare
PP_3281 -2.5 -8.0 hydroxyphenylacetyl-CoA thioesterase conserved
PP_2402 -2.4 -3.9 putative Sensor histidine kinase compare
PP_4993 -2.3 -3.5 Glutathione synthetase compare
PP_4121 -2.3 -5.3 NADH-quinone oxidoreductase subunit C/D compare
PP_0435 -2.3 -10.8 Peptidase, M23/M37 family compare
PP_5216 -2.3 -2.6 exopolyphosphatase compare
PP_4120 -2.2 -4.5 NADH-quinone oxidoreductase subunit B compare
PP_3946 -2.2 -1.6 HTH-type transcriptional repressor NicR compare
PP_4922 -2.2 -9.4 Phosphomethylpyrimidine synthase compare
PP_1734 -2.1 -2.0 Probable septum site-determining protein MinC compare
PP_4004 -2.1 -4.1 DNA translocase FtsK compare
PP_1679 -2.0 -2.7 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase compare
PP_5230 -2.0 -3.6 Tyrosine recombinase XerC compare
PP_4782 -2.0 -4.4 Phosphomethylpyrimidine kinase compare
PP_1826 -1.9 -2.3 Hydrolase, isochorismatase family compare
PP_1589 -1.9 -8.3 uridylyltransferase compare
PP_4902 -1.9 -2.9 Oligoribonuclease compare
PP_1493 -1.9 -1.9 chemotaxis response regulator protein-glutamate methylesterase of group 3 operon compare
PP_4130 -1.9 -5.0 NADH:ubiquinone oxidoreductase, membrane subunit M compare
PP_1216 -1.9 -3.0 Holliday junction ATP-dependent DNA helicase RuvA compare
PP_3271 -1.8 -5.4 phenylacetic acid-specific porin compare
PP_0127 -1.8 -2.8 Thiol:disulfide interchange protein compare
PP_1994 -1.7 -1.7 tRNA pseudouridine (38-40)synthase compare
PP_4342 -1.7 -3.0 flagellar synthesis regulator, putative ATPase compare
PP_0735 -1.7 -2.5 molybdopterin-synthase adenylyltransferase compare
PP_3662 -1.7 -6.8 conserved protein of unknown function compare
PP_2336 -1.7 -2.9 aconitate hydratase 1 compare
PP_2433 -1.7 -2.3 conserved protein of unknown function compare
PP_0319 -1.7 -2.6 conserved protein of unknown function compare
PP_3248 -1.6 -1.9 Dyp-type peroxidase family protein compare
PP_4917 -1.6 -4.1 3',5'-cyclic-nucleotide phosphodiesterase compare
PP_0833 -1.6 -1.1 queuine tRNA-ribosyltransferase compare
PP_2137 -1.6 -3.3 beta-ketoadipyl CoA thiolase, beta component compare
PP_3590 -1.6 -7.0 aromatic-amino-acid transaminase (EC 2.6.1.57) (from data) compare
PP_0368 -1.6 -6.0 putative Acyl-CoA dehydrogenase compare
PP_5313 -1.5 -3.5 DNA-binding protein HU-alpha compare
PP_1629 -1.5 -4.6 Protein RecA compare
PP_0001 -1.5 -1.3 probable chromosome-partitioning protein compare
PP_2354 -1.5 -8.7 Sensory box histidine kinase/response regulator compare
PP_1217 -1.5 -3.6 Holliday junction ATP-dependent DNA helicase RuvB compare
PP_1733 -1.4 -2.8 membrane ATPase of the MinC-MinD-MinE system compare
PP_5338 -1.4 -1.8 aspartate ammonia-lyase compare
PP_2087 -1.4 -2.6 CmpX protein compare
PP_1304 -1.4 -6.6 sulfate adenylyltransferase subunit 1/adenylyl-sulfate kinase compare
PP_5198 -1.4 -2.5 conserved protein of unknown function compare
PP_5085 -1.3 -4.6 malic enzyme B compare
PP_4131 -1.3 -4.4 NADH-quinone oxidoreductase subunit N compare
PP_5217 -1.3 -8.7 Polyphosphate kinase compare
PP_1678 -1.3 -3.0 bifunctional cobinamide-P guanylyltransferase - adenosylcobinamide kinase compare
PP_0065 -1.3 -2.4 NAD-binding component of TrK potassium transporter compare
PP_3102 -1.3 -3.2 conserved protein of unknown function compare
PP_1348 -1.3 -4.9 putative MutT/nudix family protein/thiamine-phosphate pyrophosphorylase compare
PP_2302 -1.3 -4.2 DNA-binding, ATP-dependent protease compare
PP_5331 -1.2 -2.8 Long-chain acyl-CoA thioester hydrolase compare
PP_0261 -1.2 -5.3 adenosine-3'(2'),5'-bisphosphate nucleotidase compare
PP_4826 -1.2 -6.0 Precorrin-3B C17-methyltransferase compare
PP_0063 -1.2 -1.9 putative Lipid A biosynthesis lauroyl acyltransferase compare
PP_0957 -1.2 -2.6 D-arabinose 5-phosphate isomerase compare
PP_1664 -1.2 -3.8 phosphoribosylglycinamide formyltransferase 1 compare
PP_4008 -1.2 -5.0 ATP-dependent serine protease compare
PP_3506 -1.2 -3.8 Magnesium chelatase, subunit ChII compare
PP_4126 -1.2 -1.4 NADH-quinone oxidoreductase subunit I compare
PP_0988 -1.2 -7.5 glycine dehydrogenase compare
PP_1553 -1.2 -2.6 conserved protein of unknown function compare
PP_0179 -1.2 -6.4 putative efflux transporter compare
PP_0834 -1.2 -2.4 Sec translocation complex subunit YajC compare
PP_3508 -1.2 -2.7 Protein CobW compare
PP_2000 -1.2 -1.3 amidophosphoribosyl transferase compare
PP_5717 -1.2 -2.2 conserved protein of unknown function compare
PP_4116 -1.2 -6.6 isocitrate lyase compare
PP_4129 -1.1 -2.6 NADH:ubiquinone oxidoreductase, membrane subunit L compare
PP_1291 -1.1 -6.2 PhoH family protein compare
PP_0914 -1.1 -6.8 GGDEF domain protein compare
PP_4695 -1.1 -5.1 Sensory box histidine kinase compare
PP_4880 -1.1 -5.5 exoribonuclease R compare
PP_4340 -1.1 -3.3 response regulator for chemotactic signal transduction compare
PP_5106 -1.1 -2.8 conserved inner membrane protein compare
PP_0997 -1.1 -5.8 Sigma-54 dependent transcriptional regulator/sensory box protein compare
PP_3603 -1.1 -5.2 Transcriptional regulator, GntR family compare
PP_0119 -1.1 -4.1 putative zinc uptake regulation protein ZUR compare
PP_0178 -1.1 -6.3 putative efflux pump compare
PP_5310 -1.0 -3.9 junction-specific ATP-dependent DNA helicase compare
PP_4392 -1.0 -5.5 chemotaxis protein methyltransferase compare
PP_1268 -1.0 -1.8 putative HtrA suppressor protein sohA compare
PP_4480 -1.0 -5.1 arginine N-succinyltransferase, subunit alpha compare
PP_2720 -1.0 -1.3 conserved protein of unknown function compare
PP_4546 -1.0 -2.8 ATP-dependent helicase HrpA compare
PP_1303 -1.0 -5.3 Sulfate adenylyltransferase subunit 2 compare
PP_1654 -1.0 -2.4 cysteine synthase B compare
PP_3105 -1.0 -1.3 conserved membrane protein of unknown function compare
PP_5227 -1.0 -3.5 diaminopimelate decarboxylase compare
PP_1214 -1.0 -2.4 putative transcriptional regulatory protein compare
PP_3408 -1.0 -3.5 cobalt transporter subunit A compare
PP_2132 -1.0 -2.8 Universal stress protein compare
PP_3484 -1.0 -2.9 Response regulator receiver protein compare
PP_0986 -1.0 -3.2 aminomethyltransferase compare
PP_1008 -1.0 -3.0 RNA polymerase subunit sigma-24 compare
PP_4827 -0.9 -5.2 Precorrin-2 C(20)-methyltransferase compare
PP_5028 -0.9 -1.8 proline iminopeptidase compare
PP_3649 -0.9 -2.3 Transcriptional regulator, GntR family compare
PP_0117 -0.9 -4.5 Zn(2+) ABC transporter - permease subunit compare
PP_4830 -0.9 -3.8 precorrin-6Y C(5,15)-methyltransferase compare
PP_3902 -0.9 -1.7 conserved protein of unknown function compare
PP_4338 -0.9 -4.4 Chemotaxis histidine kinase CheA compare
PP_0246 -0.9 -1.2 two-component system DNA-binding response transcriptional dual regulator compare
PP_4214 -0.9 -1.8 pyoverdine biosynthesis related protein compare


Specific Phenotypes

For 20 genes in this experiment

For carbon source Phenylacetic acid in Pseudomonas putida KT2440

For carbon source Phenylacetic acid across organisms