Experiment set12IT019 for Pseudomonas putida KT2440

Compare to:

Delta-Dodecalactone carbon source

200 most detrimental genes:

  gene name fitness t score description  
PP_1650 +5.7 50.3 Sensor protein GacS compare
PP_4099 +5.6 41.7 two-componenent system BarA/UvrY - regulatory subunit compare
PP_5003 +5.3 47.0 poly(3-hydroxyalkanoate) polymerase 1 compare
PP_2144 +4.0 11.0 Transcriptional regulator, TetR family compare
PP_5053 +3.4 10.0 Protein-export protein SecB compare
PP_5145 +3.3 30.6 phosphoenolpyruvate-dependent regulator (with NPR and NTR proteins) compare
PP_0948 +2.8 14.7 Phosphocarrier protein HPr compare
PP_4171 +2.6 9.9 conserved exported protein of unknown function compare
PP_5006 +2.5 17.1 Transcriptional regulator, TetR family compare
PP_2889 +2.2 7.0 putative Transmembrane regulator PrtR compare
PP_5045 +2.2 10.7 tRNA sulfurtransferase compare
PP_1113 +2.0 14.2 Pyridoxal-phosphate dependent enzyme family protein compare
PP_1110 +2.0 5.7 serine acetyltransferase compare
PP_1623 +2.0 14.2 RNA polymerase, sigma S (sigma 38) factor compare
PP_2387 +1.8 6.8 conserved protein of unknown function compare
PP_1761 +1.8 14.3 diguanylate cyclase with phosphodiesterase domain compare
PP_5005 +1.7 7.1 Poly(3-hydroxyalkanoate) polymerase 2 compare
PP_1109 +1.7 14.2 Transcriptional regulator, GntR family compare
PP_1111 +1.6 6.3 putative Synthetase compare
PP_5146 +1.5 7.2 RNA pyrophosphohydrolase compare
PP_1112 +1.5 6.6 conserved membrane protein of unknown function compare
PP_4215 +1.3 6.3 pyoverdine biosynthesis related protein compare
PP_4785 +1.3 5.8 conserved exported protein of unknown function compare
PP_0574 +1.2 9.2 DNA-binding response regulator, LuxR family compare
PP_5508 +1.2 2.3 conserved protein of unknown function compare
PP_2216 +1.2 4.3 short-chain acyl-CoA dehydrogenase compare
PP_0719 +1.1 0.5 ribosome-associated potassium-dependent informational ATP/GTPase compare
PP_1875 +1.1 8.4 Sensor histidine kinase/response regulator compare
PP_4561 +1.1 1.4 stress response protein compare
PP_1656 +1.1 5.9 ATP:GTP 3'-pyrophosphotransferase compare
PP_2323 +1.0 8.0 conserved protein of unknown function compare
PP_5309 +1.0 0.7 oxidative and nitrosative stress transcriptional dual regulator compare
PP_2341 +1.0 3.0 6-carboxy-5,6,7,8-tetrahydropterin synthase compare
PP_0191 +1.0 2.5 Transcriptional regulatory protein AlgQ compare
PP_5093 +1.0 2.2 twitching motility protein compare
PP_1994 +0.9 1.8 tRNA pseudouridine (38-40)synthase compare
PP_5075 +0.9 7.1 glutamate synthase (NADPH) beta subunit compare
PP_4268 +0.9 1.2 nucleoid-associated broad specificity regulator compare
PP_0630 +0.9 1.5 DNA gyrase inhibitor YacG compare
PP_0168 +0.9 8.0 putative surface adhesion protein compare
PP_4874 +0.8 0.7 50S ribosomal protein L9 compare
PP_5279 +0.8 2.7 conserved protein of unknown function compare
PP_3651 +0.8 7.1 Sensor histidine kinase/response regulator compare
PP_0166 +0.8 6.7 HlyD family secretion protein compare
PP_5076 +0.8 7.1 L-glutamate synthase(NADPH) alpha subunit compare
PP_4720 +0.8 2.0 putative RNA binding protein compare
PP_5475 +0.8 1.9 conserved protein of unknown function compare
PP_4478 +0.8 4.5 N-succinylglutamate 5-semialdehyde dehydrogenase compare
PP_t29 +0.8 1.3 tRNA-Ala compare
PP_0167 +0.8 6.9 Toxin secretion ATP-binding protein compare
PP_2148 +0.8 5.8 transcription-repair coupling factor compare
PP_3580 +0.8 2.0 conserved protein of unknown function compare
PP_1719 +0.8 5.1 Tail-specific protease prc compare
PP_0804 +0.8 4.4 Protein secretion ABC efflux system, permease and ATP-binding protein compare
PP_2846 +0.8 3.1 urease accessory protein compare
PP_4519 +0.8 6.3 Agglutination protein compare
PP_0287 +0.8 3.6 conserved exported protein of unknown function compare
PP_1186 +0.8 0.8 two component system DNA-binding transcriptional dual regulator compare
PP_1812 +0.8 3.0 conserved protein of unknown function compare
PP_4820 +0.8 3.6 tRNA-dihydrouridine synthase B compare
PP_2322 +0.8 5.0 Major outer membrane lipoprotein compare
PP_2791 +0.8 3.8 4-hydroxypentanoyl-CoA kinase, subunit LvaA (from data) compare
PP_2088 +0.7 3.2 RNA polymerase sigma factor SigX compare
PP_1307 +0.7 3.2 AsnC family transcriptional regulator compare
PP_2793 +0.7 2.5 Acyl-CoA dehydrogenase family protein compare
PP_0803 +0.7 4.8 Protein secretion ABC efflux system, membrane fusion protein compare
PP_5243 +0.7 3.8 putative hydrolase compare
PP_4424 +0.7 2.1 Uncharacterized HTH-type transcriptional regulator y4tD compare
PP_2210 +0.7 2.5 LysR family transcriptional regulator compare
PP_0250 +0.7 2.5 heat shock protein Hsp15 involved in ribosome recycling compare
PP_1048 +0.7 1.8 putative protein secretion protein for export compare
PP_0919 +0.7 1.4 conserved protein of unknown function compare
PP_0007 +0.7 1.9 conserved hypothetical protein compare
PP_4470 +0.7 3.7 putative transcriptional regulator (Arc domain-containing) compare
PP_0153 +0.7 1.8 hypothetical protein compare
PP_0806 +0.7 6.5 putative Surface adhesion protein compare
PP_0888 +0.7 1.5 Photosynthetic apparatus regulatory protein RegA compare
PP_1938 +0.7 2.3 conserved protein of unknown function compare
PP_2320 +0.7 5.1 conserved exported protein of unknown function compare
PP_0152 +0.7 3.2 conserved exported protein of unknown function compare
PP_1208 +0.7 0.9 conserved protein of unknown function, SlyX family compare
PP_1237 +0.7 0.6 4-hydroxy-tetrahydrodipicolinate synthase compare
PP_1083 +0.7 2.2 (2Fe-2S)-binding protein compare
PP_5000 +0.7 0.7 peptidase component of the ATP-dependent HslVU protease compare
PP_5140 +0.7 2.1 Transcriptional regulator, MerR family compare
PP_0165 +0.7 5.9 GGDEF domain protein compare
PP_0135 +0.7 2.6 conserved exported protein of unknown function compare
PP_1066 +0.7 4.0 C4-dicarboxylate transport transcriptional regulatory protein compare
PP_1513 +0.7 2.1 Ribosomal RNA small subunit methyltransferase J compare
PP_1075 +0.7 2.6 glycerol kinase compare
PP_4214 +0.7 2.0 pyoverdine biosynthesis related protein compare
PP_4947 +0.7 5.3 proline dehydrogenase/1-pyrroline-5-carboxylate dehydrogenase compare
PP_0355 +0.6 2.0 Response regulator compare
PP_0354 +0.6 4.3 CBS domain protein compare
PP_1141 +0.6 3.7 branched-chain amino acids ABC transporter - periplasmic leucine binding subunit compare
PP_2765 +0.6 1.3 putative Sulfonate monooxygenase MsuD compare
PP_2319 +0.6 2.6 conserved protein of unknown function compare
PP_3748 +0.6 1.6 conserved hypothetical protein compare
PP_2666 +0.6 3.8 conserved exported protein of unknown function compare
PP_4273 +0.6 1.6 Transcriptional regulator, MerR family compare
PP_5004 +0.6 2.4 Poly(3-hydroxyalkanoate) depolymerase compare
PP_0674 +0.6 4.9 ADP/ATP ratio sensor and inhibitor of translation compare
PP_4296 +0.6 1.3 conserved exported protein of unknown function compare
PP_3835 +0.6 3.0 Sensory box histidine kinase compare
PP_5201 +0.6 1.3 conserved protein of unknown function, UPF0149 family compare
PP_2002 +0.6 1.2 putative enzyme compare
PP_5495 +0.6 1.4 protein of unknown function compare
PP_5303 +0.6 2.5 aminoacrylate/iminopropionate hydrolase/deaminase compare
PP_1544 +0.6 2.6 conserved protein of unknown function compare
PP_4223 +0.6 2.3 diaminobutyrate-2-oxoglutarate transaminase compare
PP_0679 +0.6 2.7 conserved exported protein of unknown function compare
PP_2140 +0.6 3.4 conserved protein of unknown function compare
PP_4021 +0.6 4.0 non-heme chloroperoxidase compare
PP_1366 +0.6 0.5 Transcriptional regulator MvaT, P16 subunit compare
PP_2633 +0.6 1.5 conserved protein of unknown function compare
PP_2883 +0.6 1.7 conserved protein of unknown function compare
PP_4246 +0.6 4.2 Periplasmic binding protein compare
PP_2231 +0.6 0.8 putative permease of the drug/metabolite transporter (DMT) superfamily compare
PP_5256 +0.6 2.3 Cyclic nucleotide-binding protein compare
PP_5429 +0.6 2.2 protein of unknown function compare
PP_2747 +0.6 0.9 conserved protein of unknown function compare
PP_1453 +0.6 4.2 putative NUDIX hydrolase with low 3-phosphohydroxypyruvate phosphatase activity compare
PP_3504 +0.6 2.3 conserved protein of unknown function compare
PP_0805 +0.6 4.3 Outer membrane efflux protein compare
PP_2054 +0.6 1.7 putative DNA-binding transcriptional regulator compare
PP_2318 +0.6 2.8 acyl-CoA thioesterase I/protease I/lysophospholipase L1 compare
PP_2665 +0.6 2.8 Glycerol metabolism activator compare
PP_3064 +0.6 1.9 Phage tail protein compare
PP_1521 +0.6 1.7 conserved protein of unknown function compare
PP_2750 +0.6 1.9 putative Branched-chain amino acid ABC transporter, permease protein compare
PP_1698 +0.6 2.4 Major facilitator family transporter compare
PP_4942 +0.6 1.0 conserved protein of unknown function compare
PP_4435 +0.5 1.9 conserved protein of unknown function compare
PP_2189 +0.5 1.7 conserved protein of unknown function compare
PP_2753 +0.5 2.5 putative Branched-chain amino acid ABC transporter, ATP-binding protein compare
PP_5439 +0.5 2.2 conserved protein of unknown function compare
PP_3398 +0.5 1.0 putative Curli fiber surface-exposed nucleator CsgB compare
PP_5225 +0.5 0.8 frataxin compare
PP_2325 +0.5 3.4 2-dehydropantoate 2-reductase compare
PP_2253 +0.5 1.5 Transcriptional regulator, GntR family compare
PP_1007 +0.5 3.2 putative Transmembrane sensor compare
PP_0855 +0.5 1.2 conserved protein of unknown function compare
PP_0258 +0.5 2.1 regulator of murein cross-linking compare
PP_4762 +0.5 2.5 Acyl-CoA thioesterase II compare
PP_3597 +0.5 1.6 L-lysine and D-lysine ABC transporter, ATPase component (from data) compare
PP_0066 +0.5 2.4 Ribosomal RNA small subunit methyltransferase B compare
PP_5051 +0.5 1.9 conserved protein of unknown function compare
PP_2692 +0.5 3.2 putative Transporter, BCCT family compare
PP_4584 +0.5 2.1 putative endonuclease compare
PP_2682 +0.5 2.4 Fe-containing alcohol dehydrogenase compare
PP_5525 +0.5 2.0 conserved exported protein of unknown function compare
PP_3239 +0.5 1.7 putative cointegrate resolution protein T Tn4652 compare
PP_1238 +0.5 2.3 putative Lipoprotein compare
PP_0274 +0.5 1.5 putative transcriptional regulator containing HTH domain compare
PP_1803 +0.5 4.1 UDP-sugar epimerase compare
PP_2309 +0.5 1.0 conserved protein of unknown function compare
PP_1909 +0.5 2.0 putative septum formation protein compare
PP_1466 +0.5 2.0 Long-chain acyl-CoA thioester hydrolase family protein compare
PP_4768 +0.5 2.0 Exonuclease compare
PP_3286 +0.5 2.1 DNA-binding transcriptional repressor PaaX(phenylacetyl-CoA) compare
PP_2229 +0.5 1.4 putative K(+)/H(+) antiporter subunit C compare
PP_2437 +0.5 3.2 putative Acyl-CoA dehydrogenase compare
PP_3563 +0.5 2.0 conserved exported protein of unknown function compare
PP_0409 +0.5 3.4 Sensory box histidine kinase compare
PP_0359 +0.5 3.5 serine/threonine protein kinase compare
PP_2923 +0.5 2.5 conserved protein of unknown function compare
PP_3760 +0.5 3.3 putative methyltransferase compare
PP_3571 +0.5 3.2 putative Acetylornithine deacetylase compare
PP_4329 +0.5 1.7 FlhB domain protein compare
PP_3307 +0.5 1.3 conserved protein of unknown function compare
PP_5698 +0.5 2.0 conserved exported protein of unknown function compare
PP_t12 +0.5 0.8 tRNA-Thr compare
PP_4989 +0.5 1.2 Protein PilJ compare
PP_2568 +0.5 0.8 Ring-cleaving dioxygenase compare
PP_2299 +0.5 1.1 Trigger factor compare
PP_0620 +0.5 2.0 GntR family transcriptional regulator compare
PP_2480 +0.5 2.9 putative Xanthine dehydrogenase accessory factor compare
PP_0533 +0.5 2.4 histidine kinase compare
PP_2426 +0.5 2.2 coniferyl alcohol dehydrogenase compare
PP_1096 +0.5 1.3 putative electron transport complex protein compare
PP_4100 +0.5 1.7 Transcriptional regulator, Cro/CI family compare
PP_0900 +0.5 2.2 PAP2 family protein compare
PP_2526 +0.5 1.8 conserved membrane protein of unknown function compare
PP_0868 +0.5 2.2 ABC transporter ATP-binding subunit compare
PP_2970 +0.5 1.1 conserved exported protein of unknown function compare
PP_4669 +0.5 1.4 OmpA family protein compare
PP_1908 +0.5 3.5 putative Peptidase compare
PP_3730 +0.5 0.9 Transcriptional regulatory protein AruR compare
PP_4419 +0.5 1.4 transposase compare
PP_2050 +0.5 1.7 conserved protein of unknown function compare
PP_4907 +0.5 2.5 Thiosulfate sulfurtransferase compare
PP_1825 +0.5 2.2 conserved exported protein of unknown function compare
PP_4251 +0.5 2.1 cytochrome c oxidase subunit, cbb3-type compare
PP_4920 +0.5 2.8 putative Lipoprotein compare
PP_2581 +0.5 0.5 conserved protein of unknown function compare
PP_1568 +0.5 0.8 conserved protein of unknown function compare
PP_2474 +0.5 2.1 Glutathione S-transferase family protein compare
PP_0283 +0.5 1.5 Arginine/ornithine transport ATP-binding protein AotP compare
PP_2898 +0.4 1.5 conserved exported protein of unknown function compare
PP_2306 +0.4 1.3 conserved exported protein of unknown function compare


Specific Phenotypes

For 22 genes in this experiment

For carbon source Delta-Dodecalactone in Pseudomonas putida KT2440

For carbon source Delta-Dodecalactone across organisms