Experiment set12IT017 for Pseudomonas putida KT2440

Compare to:

Protocatechuic Acid carbon source

200 most detrimental genes:

  gene name fitness t score description  
PP_1650 +3.7 32.4 Sensor protein GacS compare
PP_4099 +3.7 35.9 two-componenent system BarA/UvrY - regulatory subunit compare
PP_4171 +2.4 14.9 conserved exported protein of unknown function compare
PP_4373 +1.7 13.8 Transcriptional regulator FleQ compare
PP_5053 +1.7 6.5 Protein-export protein SecB compare
PP_1623 +1.4 11.6 RNA polymerase, sigma S (sigma 38) factor compare
PP_2889 +1.4 5.0 putative Transmembrane regulator PrtR compare
PP_5232 +1.3 4.7 conserved protein of unknown function compare
PP_2387 +1.3 3.1 conserved protein of unknown function compare
PP_1428 +1.1 1.5 Sigma factor AlgU negative regulatory protein compare
PP_1344 +1.1 2.8 conserved protein of unknown function compare
PP_3738 +1.1 3.1 putative Transcriptional regulator VanR compare
PP_5248 +1.1 3.0 putative hydrolase compare
PP_4172 +1.1 5.3 conserved exported protein of unknown function compare
PP_0574 +1.0 7.9 DNA-binding response regulator, LuxR family compare
PP_2737 +1.0 2.7 Oxidoreductase, short-chain dehydrogenase/reductase family compare
PP_1113 +1.0 7.6 Pyridoxal-phosphate dependent enzyme family protein compare
PP_t29 +1.0 1.9 tRNA-Ala compare
PP_4173 +1.0 5.2 Sensor histidine kinase/response regulator compare
PP_3761 +0.9 8.1 Sensor histidine kinase/response regulator compare
PP_2152 +0.9 2.8 glycerophosphoryl diester phosphodiesterase compare
PP_1575 +0.9 1.6 conserved protein of unknown function compare
PP_1938 +0.9 2.9 conserved protein of unknown function compare
PP_3527 +0.9 6.7 Transcriptional regulator, TetR family compare
PP_4217 +0.9 8.1 outer membrane ferripyoverdine receptor FpvA, TonB-dependent compare
PP_2163 +0.9 4.7 VacJ lipoprotein compare
PP_1655 +0.9 3.6 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD compare
PP_0962 +0.9 2.0 toluene-tolerance protein compare
PP_4959 +0.8 5.8 diguanylate cyclase compare
PP_3831 +0.8 2.7 conserved protein of unknown function compare
PP_2101 +0.8 2.9 DNA-binding response regulator in two-component regulatory system with EvgS compare
PP_0958 +0.8 4.9 phospholipid ABC transporter ATP-binding subunit compare
PP_1568 +0.8 1.5 conserved protein of unknown function compare
PP_4808 +0.8 1.5 23S rRNA m3psi1915 methyltransferase compare
PP_4363 +0.8 5.5 Sensor histidine kinase/response regulator compare
PP_5580 +0.8 2.2 protein of unknown function compare
PP_0960 +0.8 3.6 phospholipid ABC transporter binding protein compare
PP_5707 +0.8 2.8 conserved protein of unknown function compare
PP_0672 +0.8 6.2 Sensory box protein compare
PP_5145 +0.8 7.2 phosphoenolpyruvate-dependent regulator (with NPR and NTR proteins) compare
PP_4942 +0.8 1.4 conserved protein of unknown function compare
PP_0125 +0.8 2.6 putative cytochrome c-type protein compare
PP_0961 +0.7 4.1 toluene tolerance protein compare
PP_0948 +0.7 2.6 Phosphocarrier protein HPr compare
PP_3938 +0.7 1.6 conserved protein of unknown function compare
PP_1663 +0.7 4.1 conserved exported protein of unknown function compare
PP_2341 +0.7 1.6 6-carboxy-5,6,7,8-tetrahydropterin synthase compare
PP_2231 +0.7 1.5 putative permease of the drug/metabolite transporter (DMT) superfamily compare
PP_1142 +0.7 1.2 conserved protein of unknown function compare
PP_1410 +0.7 1.5 conserved protein of unknown function compare
PP_0232 +0.7 1.1 ATP-binding taurine transporter subunit compare
PP_1362 +0.7 2.2 pyruvate kinase II compare
PP_0803 +0.7 4.9 Protein secretion ABC efflux system, membrane fusion protein compare
PP_0640 +0.7 3.1 conserved protein of unknown function compare
PP_4797 +0.7 1.2 conserved protein of unknown function compare
PP_2306 +0.7 1.6 conserved exported protein of unknown function compare
PP_0550 +0.7 3.7 conserved protein of unknown function compare
PP_0855 +0.6 1.7 conserved protein of unknown function compare
PP_4593 +0.6 1.6 conserved protein of unknown function compare
PP_5054 +0.6 1.3 glutaredoxin 3 compare
PP_0972 +0.6 1.6 UPF0213 protein PP_0972 compare
PP_4994 +0.6 2.6 conserved protein of unknown function compare
PP_0674 +0.6 4.4 ADP/ATP ratio sensor and inhibitor of translation compare
PP_4265 +0.6 1.9 DNA-binding transcriptional dual regulator compare
PP_4213 +0.6 1.5 putative dipeptidase compare
PP_0959 +0.6 1.1 phospholipid ABC transporter compare
PP_4073 +0.6 2.2 conserved exported protein of unknown function compare
PP_1097 +0.6 1.3 Methionine--tRNA ligase compare
PP_0173 +0.6 3.2 putative transcriptional factor-related protein compare
PP_5093 +0.6 0.8 twitching motility protein compare
PP_5256 +0.6 3.1 Cyclic nucleotide-binding protein compare
PP_2118 +0.6 1.8 conserved protein of unknown function compare
PP_2060 +0.6 1.4 DNA-binding transcriptional dual regulator - SoxR-reversible one-electron oxidation of its [2Fe-2S] cluster, NADPH-dependent compare
PP_5609 +0.6 2.1 conserved protein of unknown function compare
PP_0805 +0.6 4.1 Outer membrane efflux protein compare
PP_5058 +0.6 2.5 Carboxy-terminal-processing protease compare
PP_3239 +0.6 1.5 putative cointegrate resolution protein T Tn4652 compare
PP_2684 +0.6 1.7 conserved membrane protein of unknown function compare
PP_1384 +0.6 3.0 Probable efflux pump outer membrane protein TtgC compare
PP_1656 +0.6 3.2 ATP:GTP 3'-pyrophosphotransferase compare
PP_2413 +0.6 4.2 GGDEF family protein compare
PP_3052 +0.6 1.1 conserved protein of unknown function compare
PP_4262 +0.6 1.7 Cytochrome oxidase maturation protein, cbb3-type compare
PP_2219 +0.6 2.1 conserved protein of unknown function compare
PP_0846 +0.5 0.6 DnaK-like molecular chaperone specific for IscU compare
PP_0355 +0.5 1.8 Response regulator compare
PP_4273 +0.5 1.4 Transcriptional regulator, MerR family compare
PP_0806 +0.5 4.9 putative Surface adhesion protein compare
PP_2568 +0.5 0.9 Ring-cleaving dioxygenase compare
PP_0905 +0.5 1.5 conserved exported protein of unknown function compare
PP_2498 +0.5 2.8 conserved protein of unknown function compare
PP_2309 +0.5 1.1 conserved protein of unknown function compare
PP_0683 +0.5 1.8 conserved protein of unknown function compare
PP_1109 +0.5 4.1 Transcriptional regulator, GntR family compare
PP_2650 +0.5 1.5 putative 4-hydroxybutyrate dehydrogenase compare
PP_0743 +0.5 3.2 conserved protein with NAD(P)-binding Rossmann-fold domain compare
PP_0332 +0.5 1.7 putative Acyltransferase compare
PP_2459 +0.5 1.4 ribose pyranase compare
PP_0719 +0.5 0.2 ribosome-associated potassium-dependent informational ATP/GTPase compare
PP_5000 +0.5 1.0 peptidase component of the ATP-dependent HslVU protease compare
PP_2616 +0.5 1.7 conserved protein of unknown function compare
PP_4710 +0.5 3.3 tRNA pseudouridine 55 synthase compare
PP_3884 +0.5 2.4 Phage holin, lambda family compare
PP_3127 +0.5 3.2 putative Exopolysaccharide transport protein compare
PP_2675 +0.5 1.2 Cytochrome c-type protein compare
PP_5322 +0.5 3.0 putative metal ion transporter compare
PP_2581 +0.5 1.0 conserved protein of unknown function compare
PP_0086 +0.5 1.4 conserved protein of unknown function compare
PP_0007 +0.5 1.3 conserved hypothetical protein compare
PP_3293 +0.5 3.0 conserved membrane protein of unknown function compare
PP_2740 +0.5 1.4 Transcriptional regulator, MerR family compare
PP_1324 +0.5 2.1 putative endonuclease distantly related to archaeal Holliday junction resolvase compare
PP_2500 +0.5 2.4 conserved protein of unknown function compare
PP_2408 +0.5 3.0 cobalt-zinc-cadmium resistance protein compare
PP_5490 +0.5 2.3 site-specific DNA recombinase compare
PP_1385 +0.5 3.8 Probable efflux pump membrane transporter TtgB compare
PP_1692 +0.5 1.5 conserved protein of unknown function compare
PP_5223 +0.5 1.9 regulator of nucleotide diphosphokinase compare
PP_1898 +0.5 1.6 MotA/TolQ/ExbB proton channel family protein compare
PP_2533 +0.5 1.6 D-isomer specific 2-hydroxyacid dehydrogenase family protein compare
PP_1521 +0.5 1.0 conserved protein of unknown function compare
PP_0250 +0.5 1.1 heat shock protein Hsp15 involved in ribosome recycling compare
PP_5451 +0.5 2.9 protein of unknown function compare
PP_5654 +0.5 1.1 putative phosphotriesterase compare
PP_5533 +0.5 1.0 conserved protein of unknown function compare
PP_1397 +0.5 1.9 conserved protein of unknown function compare
PP_2748 +0.5 0.9 putative Branched-chain amino acid ABC transporter, ATP-binding protein compare
PP_3760 +0.5 2.8 putative methyltransferase compare
PP_1909 +0.5 2.0 putative septum formation protein compare
PP_3929 +0.5 2.0 conserved protein of unknown function compare
PP_1208 +0.5 1.1 conserved protein of unknown function, SlyX family compare
PP_5059 +0.4 2.0 conserved exported protein of unknown function compare
PP_2404 +0.4 2.0 conserved exported protein of unknown function compare
PP_3926 +0.4 1.2 short-chain dehydrogenase compare
PP_4916 +0.4 1.8 putative esterase compare
PP_5309 +0.4 0.3 oxidative and nitrosative stress transcriptional dual regulator compare
PP_0276 +0.4 0.8 Transcriptional regulator, Cro/CI family compare
PP_0627 +0.4 1.0 conserved protein of unknown function compare
PP_1633 +0.4 1.1 conserved exported protein of unknown function compare
PP_5247 +0.4 2.3 conserved protein of unknown function compare
PP_2257 +0.4 2.7 putative aerotaxis receptor compare
PP_5456 +0.4 1.0 conserved protein of unknown function compare
PP_1112 +0.4 2.2 conserved membrane protein of unknown function compare
PP_2373 +0.4 1.0 conserved protein of unknown function compare
PP_0185 +0.4 2.8 Positive alginate biosynthesis regulatory protein compare
PP_1808 +0.4 1.2 glucose-6-phosphate isomerase compare
PP_5477 +0.4 1.8 conserved protein of unknown function compare
PP_3812 +0.4 3.0 putative Lipase compare
PP_2970 +0.4 1.6 conserved exported protein of unknown function compare
PP_1761 +0.4 3.4 diguanylate cyclase with phosphodiesterase domain compare
PP_1968 +0.4 2.0 TetR family transcriptional regulator compare
PP_0411 +0.4 2.0 Polyamine ABC transporter, ATP-binding protein compare
PP_4311 +0.4 2.6 putative D-amino acid dehydrogenase 2 small subunit compare
PP_1386 +0.4 2.4 Probable efflux pump periplasmic linker TtgA compare
PP_5267 +0.4 1.2 putative cytochrome c5 compare
PP_4296 +0.4 0.6 conserved exported protein of unknown function compare
PP_3141 +0.4 2.3 Glycosyl transferase, WecB/TagA/CpsF family compare
PP_0424 +0.4 1.5 DNA-binding transcriptional dual regulator compare
PP_2127 +0.4 1.3 Sensor histidine kinase compare
PP_4560 +0.4 1.5 putative Ribonuclease BN compare
PP_3892 +0.4 1.0 conserved protein of unknown function compare
PP_5508 +0.4 0.7 conserved protein of unknown function compare
PP_3597 +0.4 2.3 L-lysine and D-lysine ABC transporter, ATPase component (from data) compare
PP_5279 +0.4 1.2 conserved protein of unknown function compare
PP_2358 +0.4 1.9 putative Type 1 pili subunit CsuA/B protein compare
PP_2457 +0.4 2.8 DNA-binding transcriptional repressor compare
PP_4769 +0.4 1.3 conserved protein of unknown function compare
PP_3577 +0.4 2.2 RNA polymerase, sigma 19 factor compare
PP_2791 +0.4 1.9 4-hydroxypentanoyl-CoA kinase, subunit LvaA (from data) compare
PP_2105 +0.4 1.8 conserved protein of unknown function compare
PP_0587 +0.4 2.3 conserved exported protein of unknown function compare
PP_0241 +0.4 1.1 Transporter compare
PP_4100 +0.4 1.5 Transcriptional regulator, Cro/CI family compare
PP_2083 +0.4 1.5 putative Lipase compare
PP_4975 +0.4 2.2 Long-chain acyl-CoA thioester hydrolase family protein compare
PP_4631 +0.4 1.8 conserved protein of unknown function compare
PP_1239 +0.4 1.5 Metallo-beta-lactamase family protein compare
PP_0251 +0.4 2.1 conserved membrane protein of unknown function compare
PP_4541 +0.4 2.4 peptidyl-prolyl cis-trans isomerase A (rotamase A) compare
PP_2512 +0.4 2.2 GTP cyclohydrolase 1 compare
PP_2525 +0.4 1.0 conserved protein of unknown function compare
PP_4263 +0.4 1.7 putative membrane-bounded cytochrome biogenesis cycZ-like domain, copper tolerance protein compare
PP_5359 +0.4 1.5 CobW/P47K family protein compare
PP_2437 +0.4 2.6 putative Acyl-CoA dehydrogenase compare
PP_0385 +0.4 1.9 putative serine acetyltransferase compare
PP_5283 +0.4 2.2 periplasmic dipeptide transport protein compare
PP_5001 +0.4 1.1 protease HslVU, ATPase component compare
PP_5698 +0.4 1.7 conserved exported protein of unknown function compare
PP_2535 +0.4 1.5 putative inner membrane transport protein compare
PP_2474 +0.4 1.4 Glutathione S-transferase family protein compare
PP_3651 +0.4 3.0 Sensor histidine kinase/response regulator compare
PP_2848 +0.4 0.9 urease accessory protein compare
PP_0126 +0.4 1.4 Cytochrome c4 compare
PP_1827 +0.4 1.9 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase compare
PP_1325 +0.4 1.7 putative lipoprotein compare
PP_3136 +0.4 1.4 putative O-acetyltransferase compare
PP_1141 +0.4 2.2 branched-chain amino acids ABC transporter - periplasmic leucine binding subunit compare
PP_3294 +0.4 2.0 Universal stress protein family compare
PP_5070 +0.4 1.9 ParA family protein compare
PP_0274 +0.4 1.0 putative transcriptional regulator containing HTH domain compare


Specific Phenotypes

For 8 genes in this experiment

For carbon source Protocatechuic Acid in Pseudomonas putida KT2440

For carbon source Protocatechuic Acid across organisms