Experiment set12IT009 for Pseudomonas putida KT2440

Compare to:

1,4-Butanediol carbon source

200 most important genes:

  gene name fitness t score description  
PP_1985 -7.4 -5.1 3-isopropylmalate dehydratase large subunit compare
PP_2049 -7.3 -5.1 Alcohol dehydrogenase, iron-containing conserved
PP_0787 -7.1 -4.9 quinolinate phosphoribosyltransferase (decarboxylating) monomer compare
PP_3511 -7.0 -6.9 Branched-chain-amino-acid aminotransferase compare
PP_5098 -6.8 -4.7 methionine biosynthesis protein MetW compare
PP_5097 -6.6 -10.0 homoserine O-acetyltransferase compare
PP_2001 -6.4 -9.8 O-succinylhomoserine sulfhydrylase compare
PP_4678 -6.3 -14.1 Ketol-acid reductoisomerase compare
PP_0967 -6.3 -11.3 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
PP_1986 -6.1 -4.2 3-isopropylmalate dehydratase small subunit compare
PP_1025 -5.8 -17.4 2-isopropylmalate synthase compare
PP_4679 -5.7 -7.8 acetohydroxybutanoate synthase / acetolactate synthase compare
PP_4680 -5.7 -14.3 acetohydroxybutanoate synthase / acetolactate synthase compare
PP_4723 -5.7 -5.5 Carbamoyl-phosphate synthase large chain compare
PP_2168 -5.6 -10.1 Transaldolase compare
PP_0966 -5.6 -13.0 Histidinol dehydrogenase compare
PP_1231 -5.5 -7.6 quinolinate synthase [4Fe-4S] cluster subunit compare
PP_0422 -5.5 -7.5 Indole-3-glycerol phosphate synthase compare
PP_0417 -5.5 -20.4 Anthranilate synthase component 1 compare
PP_1988 -5.4 -10.1 3-isopropylmalate dehydrogenase compare
PP_1079 -5.4 -6.5 Ornithine carbamoyltransferase compare
PP_0293 -5.3 -3.6 Imidazole glycerol phosphate synthase subunit HisF compare
PP_0965 -5.2 -10.8 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
PP_4724 -5.2 -6.1 Carbamoyl-phosphate synthase small chain compare
PP_5155 -5.2 -5.8 D-3-phosphoglycerate dehydrogenase / alpha-ketoglutarate reductase compare
PP_5015 -5.1 -5.6 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
PP_2328 -5.0 -7.7 Phosphoadenosine phosphosulfate reductase compare
PP_0691 -5.0 -4.8 Glutamate 5-kinase compare
PP_2371 -5.0 -8.9 Sulphite reductase hemoprotein, beta subunit compare
PP_4890 -4.9 -6.5 ATP phosphoribosyltransferase regulatory subunit compare
PP_3662 -4.9 -10.4 conserved protein of unknown function compare
PP_1088 -4.8 -9.3 Argininosuccinate synthase compare
PP_4058 -4.8 -12.1 1,4-alpha-glucan branching enzyme compare
PP_0290 -4.6 -7.7 Imidazole glycerol phosphate synthase subunit HisH compare
PP_2370 -4.6 -4.4 conserved protein of unknown function compare
PP_5128 -4.5 -7.2 Dihydroxy-acid dehydratase compare
PP_5289 -4.5 -5.3 Acetylglutamate kinase compare
PP_0289 -4.5 -9.1 Imidazoleglycerol-phosphate dehydratase compare
PP_5185 -4.5 -7.4 acetylglutamate kinase-like protein (regulatory domain)/amino acid N-acetyltransferase compare
PP_2327 -4.4 -6.8 transcriptional dual regulator / CysB-O-acetyl-L-serine compare
PP_0082 -4.4 -3.1 tryptophan synthase alpha chain compare
PP_0420 -4.4 -11.0 aminodeoxychorismate synthase / para-aminobenzoate synthase multi-enzyme complex compare
PP_4364 -4.4 -5.7 putative Anti-sigma F factor antagonist compare
PP_0292 -4.4 -4.8 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
PP_0184 -4.4 -3.0 Argininosuccinate lyase compare
PP_0083 -4.3 -5.1 tryptophan synthase beta chain compare
PP_2433 -4.3 -2.5 conserved protein of unknown function compare
PP_3999 -4.3 -9.2 Uroporphyrinogen-III C-methyltransferase/Precorrin-2 dehydrogenase/Sirohydrochlorin ferrochelatase compare
PP_0381 -4.3 -9.5 Coenzyme PQQ synthesis protein F compare
PP_4977 -4.2 -12.1 5,10-methylenetetrahydrofolate reductase compare
PP_0421 -4.2 -7.6 Anthranilate phosphoribosyltransferase compare
PP_2047 -4.1 -4.9 3-hydroxyacyl-CoA dehydrogenase family protein compare
PP_0164 -4.0 -10.0 conserved protein of unknown function compare
PP_2375 -4.0 -14.1 cobalamin-dependent methionine synthase compare
PP_1995 -4.0 -9.6 N-(5'-phosphoribosyl)anthranilate isomerase compare
PP_0339 -4.0 -2.7 Pyruvate dehydrogenase E1 component compare
PP_5014 -3.9 -5.3 Phosphoribosyl-AMP cyclohydrolase compare
PP_4943 -3.9 -2.7 putative Glycosyl transferase compare
PP_2326 -3.7 -10.8 Universal stress protein compare
PP_1198 -3.7 -5.7 transcriptional regulator, Cro/CI family (higA antitoxin like) compare
PP_4120 -3.5 -3.4 NADH-quinone oxidoreductase subunit B compare
PP_3484 -3.5 -5.7 Response regulator receiver protein compare
PP_4799 -3.5 -3.4 putative Muramoyltetrapeptide carboxypeptidase compare
PP_4342 -3.5 -2.4 flagellar synthesis regulator, putative ATPase compare
PP_4131 -3.4 -5.6 NADH-quinone oxidoreductase subunit N compare
PP_1426 -3.3 -12.2 L-aspartate oxidase compare
PP_0735 -3.3 -2.6 molybdopterin-synthase adenylyltransferase compare
PP_1328 -3.2 -3.0 Protein MraZ compare
PP_4129 -3.1 -3.0 NADH:ubiquinone oxidoreductase, membrane subunit L compare
PP_4696 -3.1 -3.6 Nitrogen regulation protein NR(I) compare
PP_4480 -3.0 -8.3 arginine N-succinyltransferase, subunit alpha compare
PP_1589 -3.0 -8.9 uridylyltransferase compare
PP_4909 -3.0 -9.0 phosphoserine phosphatase compare
PP_4126 -2.9 -2.0 NADH-quinone oxidoreductase subunit I compare
PP_0377 -2.9 -2.8 coenzyme PQQ synthesis protein D compare
PP_2682 -2.7 -4.9 Fe-containing alcohol dehydrogenase compare
PP_1468 -2.6 -2.6 Tyrosine recombinase XerD compare
PP_4700 -2.5 -1.7 pantothenate synthetase compare
PP_1217 -2.5 -3.7 Holliday junction ATP-dependent DNA helicase RuvB compare
PP_4999 -2.5 -2.6 dihydroorotase-like protein compare
PP_3603 -2.4 -7.0 Transcriptional regulator, GntR family compare
PP_4779 -2.3 -11.8 AMP nucleosidase compare
PP_1493 -2.2 -2.7 chemotaxis response regulator protein-glutamate methylesterase of group 3 operon compare
PP_1678 -2.2 -4.7 bifunctional cobinamide-P guanylyltransferase - adenosylcobinamide kinase compare
PP_1304 -2.2 -7.7 sulfate adenylyltransferase subunit 1/adenylyl-sulfate kinase compare
PP_0185 -2.2 -7.4 Positive alginate biosynthesis regulatory protein compare
PP_0378 -2.2 -6.1 Pyrroloquinoline-quinone synthase compare
PP_5248 -2.2 -2.2 putative hydrolase compare
PP_4902 -2.2 -2.6 Oligoribonuclease compare
PP_5313 -2.2 -2.3 DNA-binding protein HU-alpha compare
PP_1681 -2.1 -8.2 cobalamin 5'-phosphate synthase / Cobalamin synthase compare
PP_4832 -2.1 -4.2 Precorrin-6x reductase compare
PP_0852 -2.1 -3.7 Transcriptional regulator, Cro/CI family compare
PP_2132 -2.1 -4.3 Universal stress protein compare
PP_1673 -2.1 -5.3 cobyrinate a,c-diamide synthase compare
PP_5090 -2.1 -2.5 putative cell division protein compare
PP_4826 -2.1 -5.1 Precorrin-3B C17-methyltransferase compare
PP_1233 -2.1 -3.6 sulfurtransferase compare
PP_4124 -2.1 -3.9 NADH-quinone oxidoreductase subunit G compare
PP_0376 -2.1 -6.1 Coenzyme PQQ synthesis protein E compare
PP_5075 -2.1 -8.3 glutamate synthase (NADPH) beta subunit compare
PP_5095 -2.0 -2.2 pyrroline-5-carboxylate reductase compare
PP_3507 -2.0 -9.5 Aerobic cobaltochelatase subunit CobN compare
PP_4121 -2.0 -4.3 NADH-quinone oxidoreductase subunit C/D compare
PP_3075 -2.0 -4.4 putative transcriptional regulator compare
PP_2665 -2.0 -4.3 Glycerol metabolism activator compare
PP_3649 -2.0 -2.9 Transcriptional regulator, GntR family compare
PP_2336 -2.0 -2.3 aconitate hydratase 1 compare
PP_4827 -2.0 -7.6 Precorrin-2 C(20)-methyltransferase compare
PP_5202 -1.9 -2.0 putative cell division protein compare
PP_1778 -1.9 -5.0 Lipopolysaccharide ABC export system, permease protein compare
PP_0117 -1.8 -5.9 Zn(2+) ABC transporter - permease subunit compare
PP_5017 -1.8 -1.5 Sec-independent protein translocase protein TatB compare
PP_4122 -1.8 -2.3 proton-pumping NADH:ubiquinone oxidoreductase, respiratory complex I, subunit E compare
PP_4828 -1.8 -1.5 Precorrin-8X methylmutase compare
PP_1677 -1.8 -5.1 Adenosyl-cobyric acid synthase compare
PP_1654 -1.8 -3.4 cysteine synthase B compare
PP_1215 -1.8 -1.4 Crossover junction endodeoxyribonuclease RuvC compare
PP_0379 -1.7 -4.8 Coenzyme PQQ synthesis protein B compare
PP_3505 -1.7 -1.7 conserved protein of unknown function compare
PP_1428 -1.7 -1.1 Sigma factor AlgU negative regulatory protein compare
PP_1303 -1.7 -4.9 Sulfate adenylyltransferase subunit 2 compare
PP_3506 -1.6 -2.9 Magnesium chelatase, subunit ChII compare
PP_2414 -1.6 -2.9 conserved exported protein of unknown function compare
PP_2000 -1.6 -1.1 amidophosphoribosyl transferase compare
PP_1675 -1.6 -5.9 Subunit of adenosylcobinamide-phosphate synthase beta component compare
PP_1628 -1.6 -4.2 NMN amidohydrolase compare
PP_4993 -1.6 -3.0 Glutathione synthetase compare
PP_2087 -1.6 -2.1 CmpX protein compare
PP_1679 -1.6 -2.5 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase compare
PP_4010 -1.6 -5.6 DNA replication inhibitor compare
PP_2046 -1.6 -1.3 Transcriptional regulator, LysR family compare
PP_4130 -1.5 -3.5 NADH:ubiquinone oxidoreductase, membrane subunit M compare
PP_0914 -1.5 -7.6 GGDEF domain protein compare
PP_4273 -1.5 -2.2 Transcriptional regulator, MerR family compare
PP_0291 -1.5 -2.2 conserved protein of unknown function compare
PP_5104 -1.5 -5.0 thiazole synthase compare
PP_4504 -1.5 -1.3 conserved exported protein of unknown function compare
PP_0775 -1.5 -2.1 conserved protein of unknown function compare
PP_0405 -1.5 -9.9 conserved protein of unknown function compare
PP_4009 -1.5 -5.0 ATP-dependent Clp protease adapter protein ClpS compare
PP_5748 -1.5 -2.1 cytochrome c heme lyase subunit compare
PP_1676 -1.4 -3.5 subunit of adenosylcobinamide-phosphate synthase beta component compare
PP_1733 -1.4 -2.3 membrane ATPase of the MinC-MinD-MinE system compare
PP_0261 -1.4 -5.0 adenosine-3'(2'),5'-bisphosphate nucleotidase compare
PP_4880 -1.4 -6.4 exoribonuclease R compare
PP_4793 -1.4 -2.0 conserved protein of unknown function compare
PP_1325 -1.4 -4.2 putative lipoprotein compare
PP_3248 -1.4 -1.6 Dyp-type peroxidase family protein compare
PP_0986 -1.4 -3.3 aminomethyltransferase compare
PP_0833 -1.4 -0.9 queuine tRNA-ribosyltransferase compare
PP_3539 -1.4 -2.5 putative Transcriptional regulator compare
PP_3074 -1.4 -3.3 D-beta-hydroxybutyrate permease compare
PP_1142 -1.3 -1.2 conserved protein of unknown function compare
PP_2331 -1.3 -5.3 conserved membrane protein of unknown function compare
PP_0995 -1.3 -5.1 conserved membrane protein of unknown function compare
PP_0434 -1.3 -7.1 Anhydro-N-acetylmuramic acid kinase compare
PP_0963 -1.3 -3.3 putative BolA family protein compare
PP_3449 -1.3 -3.3 conserved exported protein of unknown function compare
PP_1672 -1.3 -3.1 cob(I)alamin adenolsyltransferase/cobinamide ATP-dependent adenolsyltransferase compare
PP_0872 -1.3 -3.8 Peptide chain release factor 3 compare
PP_2291 -1.3 -1.3 conserved protein of unknown function compare
PP_3508 -1.2 -1.8 Protein CobW compare
PP_4695 -1.2 -5.9 Sensory box histidine kinase compare
PP_2082 -1.2 -6.8 phosphoenolpyruvate synthetase compare
PP_0406 -1.2 -4.4 Nucleotidyltransferase family protein compare
PP_2088 -1.2 -2.9 RNA polymerase sigma factor SigX compare
PP_0409 -1.2 -4.9 Sensory box histidine kinase compare
PP_1994 -1.2 -1.3 tRNA pseudouridine (38-40)synthase compare
PP_2675 -1.2 -2.9 Cytochrome c-type protein compare
PP_4830 -1.2 -3.0 precorrin-6Y C(5,15)-methyltransferase compare
PP_2123 -1.2 -4.8 molybdenum::molybdopterin ligase compare
PP_2683 -1.2 -2.5 putative sensory box histidine kinase/response regulator compare
PP_0593 -1.2 -1.1 putative ribosome-binding factor compare
PP_1355 -1.1 -8.6 Muropeptide permease AmpG compare
PP_1216 -1.1 -2.0 Holliday junction ATP-dependent DNA helicase RuvA compare
PP_0789 -1.1 -3.4 N-acetyl-anhydromuramyl-L-alanine-amidase compare
PP_4829 -1.1 -1.8 putative precorrin-3B synthase compare
PP_2335 -1.1 -6.0 methylcitrate synthase compare
PP_4136 -1.1 -1.1 Transcriptional regulator, LuxR family compare
PP_5035 -1.1 -3.2 Histidine utilization repressor compare
PP_1860 -1.1 -3.4 Organic hydroperoxide resistance transcriptional regulator compare
PP_0516 -1.1 -2.5 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II compare
PP_1605 -1.1 -2.5 Ribonuclease HII compare
PP_5230 -1.1 -2.3 Tyrosine recombinase XerC compare
PP_2889 -1.1 -4.1 putative Transmembrane regulator PrtR compare
PP_0120 -1.1 -4.4 putative zinc ABC transporter compare
PP_4782 -1.1 -2.8 Phosphomethylpyrimidine kinase compare
PP_5027 -1.1 -2.2 D-tyrosyl-tRNA(Tyr) deacylase compare
PP_0958 -1.1 -3.2 phospholipid ABC transporter ATP-binding subunit compare
PP_3731 -1.1 -5.0 Transcriptional regulator, TetR family compare
PP_0319 -1.1 -1.0 conserved protein of unknown function compare
PP_0232 -1.1 -1.0 ATP-binding taurine transporter subunit compare
PP_3102 -1.1 -2.7 conserved protein of unknown function compare
PP_3892 -1.1 -1.6 conserved protein of unknown function compare
PP_2253 -1.0 -1.2 Transcriptional regulator, GntR family compare
PP_0959 -1.0 -1.6 phospholipid ABC transporter compare
PP_4776 -1.0 -4.7 AsnC family transcriptional regulator compare
PP_5329 -1.0 -2.7 putative phosphate ABC transporter, periplasmic phosphate-binding protein compare
PP_4363 -1.0 -5.0 Sensor histidine kinase/response regulator compare


Specific Phenotypes

For 12 genes in this experiment

For carbon source 1,4-Butanediol in Pseudomonas putida KT2440

For carbon source 1,4-Butanediol across organisms