Experiment set11S546 for Escherichia coli BL21

Compare to:

Tailocin 264

200 most important genes:

  gene name fitness t score description  
ECD_03983 -8.5 -13.6 sensory histidine kinase in two-component regulatory system with BasR compare
ECD_03984 -8.4 -11.5 response regulator in two-component regulatory system with BasS compare
ECD_00414 -7.7 -5.3 multidrug efflux system compare
ECD_00413 -7.6 -10.4 multidrug efflux system protein compare
ECD_02907 -5.4 -3.7 transport channel compare
ECD_03486 -5.2 -8.7 UDP-glucose:(Glucosyl) LPS alpha1,3-glucosyltransferase WaaO compare
ECD_03257 -4.1 -2.8 response regulator in two-component regulatory system with EnvZ compare
ECD_04038 -4.0 -2.7 delta(2)-isopentenylpyrophosphate tRNA-adenosine transferase compare
ECD_00933 -3.9 -2.7 outer membrane porin 1a (Ia compare
ECD_03119 -3.8 -2.6 global DNA-binding transcriptional dual regulator compare
ECD_03036 -3.6 -4.3 transcription termination/antitermination L factor compare
ECD_03746 -3.2 -4.6 periplasmic protein disulfide isomerase I compare
ECD_03256 -2.8 -7.3 sensory histidine kinase in two-component regulatory system with OmpR compare
ECD_02399 -2.8 -2.7 GMP synthetase (glutamine aminotransferase) compare
ECD_03752 -2.6 -11.1 coproporphyrinogen III oxidase, SAM and NAD(P)H dependent, oxygen-independent compare
ECD_02178 -2.4 -7.4 putative LPS core heptose(II)-phosphate phosphatase compare
ECD_02404 -2.3 -2.6 BamABCDE complex OM biogenesis lipoprotein compare
ECD_02726 -2.1 -4.5 site-specific tyrosine recombinase compare
ECD_03132 -2.1 -2.0 dehydroshikimate reductase, NAD(P)-binding compare
ECD_03797 -2.0 -4.8 sensory histidine kinase in two-component regulatory system with CpxR compare
ECD_02832 -1.9 -1.8 putative type II secretion protein GspJ compare
ECD_01160 -1.8 -6.5 oxidoreductase that catalyzes reoxidation of DsbA protein disulfide isomerase I compare
ECD_00634 -1.7 -2.9 N-acetylglucosamine-6-phosphate deacetylase compare
ECD_01802 -1.7 -4.5 RNA chaperone, putative ProP translation regulator compare
ECD_01162 -1.7 -2.6 fatty acid metabolism regulon transcriptional regulator compare
ECD_02465 -1.6 -8.9 anti-sigma E factor, binds RseA compare
ECD_02549 -1.5 -7.1 DNA recombination and repair protein; ssDNA-dependent ATPase; synaptase; ssDNA and dsDNA binding protein; ATP-dependent homologous DNA strand exchanger; recombinase A; LexA autocleavage cofactor compare
ECD_03046 -1.5 -4.4 transcript cleavage factor compare
ECD_01489 -1.5 -2.3 transcriptional repressor of multiple antibiotic resistance compare
ECD_02423 -1.5 -6.2 isc operon transcriptional repressor; suf operon transcriptional activator; oxidative stress- and iron starvation-inducible; autorepressor compare
ECD_01565 -1.5 -1.3 putative arabinose efflux transporter compare
ECD_01250 -1.5 -2.4 DNA topoisomerase I, omega subunit compare
ECD_02181 -1.4 -8.1 fused UDP-L-Ara4N formyltransferase/UDP-GlcA C-4'-decarboxylase compare
ECD_02318 -1.4 -1.8 pyridoxal-pyridoxamine kinase/hydroxymethylpyrimidine kinase compare
ECD_02857 -1.4 -1.2 hypothetical protein compare
ECD_03118 -1.4 -5.3 tRNA-dihydrouridine synthase B compare
ECD_01930 -1.4 -7.5 UDP-glucose 6-dehydrogenase compare
ECD_00053 -1.3 -2.5 diadenosine tetraphosphatase compare
ECD_02180 -1.3 -7.7 undecaprenyl phosphate-L-Ara4FN transferase compare
ECD_t00083 -1.3 -2.5 tRNA-Leu compare
ECD_03590 -1.3 -1.7 tRNA U34 5-methylaminomethyl-2-thiouridine modification GTPase compare
ECD_00387 -1.3 -5.7 peptidyl-prolyl cis/trans isomerase (trigger factor) compare
ECD_03121 -1.3 -1.2 putative membrane protein compare
ECD_03877 -1.3 -3.2 HU, DNA-binding transcriptional regulator, alpha subunit compare
ECD_02179 -1.2 -7.1 uridine 5'-(beta-1-threo-pentapyranosyl-4-ulose diphosphate) aminotransferase, PLP-dependent compare
ECD_00061 -1.2 -10.5 RNA polymerase remodeling/recycling factor ATPase; RNA polymerase-associated, ATP-dependent RNA translocase compare
ECD_02400 -1.2 -2.8 IMP dehydrogenase compare
ECD_01763 -1.2 -1.7 diguanylate cyclase compare
ECD_03612 -1.2 -7.3 phosphate ABC transporter periplasmic binding protein compare
ECD_00392 -1.2 -4.9 HU, DNA-binding transcriptional regulator, beta subunit compare
ECD_02470 -1.2 -3.4 ATP-dependent RNA helicase compare
ECD_03625 -1.2 -3.3 5-methylaminomethyl-2-thiouridine modification at tRNA U34 compare
ECD_03067 -1.2 -1.7 RNA polymerase, sigma 54 (sigma N) factor compare
ECD_02505 -1.2 -9.0 lipoprotein component of BamABCDE OM biogenesis complex compare
ECD_03425 -1.2 -1.8 putative hydrogenase, 4Fe-4S ferredoxin-type component compare
ECD_03668 -1.2 -3.4 TDP-fucosamine acetyltransferase compare
ECD_03813 -1.1 -2.2 FtsZ stabilizer, septal ring assembly factor, cell division stimulator compare
ECD_00176 -1.1 -1.2 periplasmic chaperone compare
ECD_00961 -1.1 -4.8 outer membrane protein A (3a compare
ECD_04107 -1.1 -1.8 trehalose-6-P hydrolase compare
ECD_02114 -1.1 -4.6 putative ATP-dependent DNA or RNA helicase compare
ECD_02405 -1.1 -2.2 ancillary SecYEG translocon subunit; putative anti-RcsB factor compare
ECD_03731 -1.1 -2.1 TatABCE protein translocation system subunit compare
ECD_02039 -1.1 -1.1 hypothetical protein compare
ECD_00450 -1.1 -1.5 conserved protein, rhs-like protein compare
ECD_02183 -1.1 -5.2 4-amino-4-deoxy-L-arabinose transferase compare
ECD_03669 -1.1 -3.6 TDP-4-oxo-6-deoxy-D-glucose transaminase compare
ECD_03017 -1.1 -1.9 outer membrane lipoprotein compare
ECD_01562 -1.1 -2.1 putative dethiobiotin synthetase compare
ECD_01591 -1.0 -2.0 PLP-dependent beta-cystathionase and maltose regulon regulator compare
ECD_02774 -1.0 -2.8 Zn-dependent metalloprotease-related protein compare
ECD_02076 -1.0 -1.6 dihydropyrimidine dehydrogenase, NADH-dependent, subunit C compare
ECD_01211 -1.0 -3.0 PcnB-degradosome interaction factor; response regulator compare
ECD_01349 -1.0 -2.0 pyruvate-flavodoxin oxidoreductase compare
ECD_01785 -0.9 -3.1 putative membrane-anchored cyclic-di-GMP phosphodiesterase, regulator of cellulose production compare
ECD_03897 -0.9 -3.7 glucosephosphate isomerase compare
ECD_02182 -0.9 -4.1 undecaprenyl phosphate-alpha-L-ara4FN deformylase compare
ECD_04091 -0.9 -5.9 translocation and assembly module for autotransporter export, outer membrane subunit compare
ECD_01700 -0.9 -2.0 cell division modulator compare
ECD_00434 -0.9 -1.2 putative DNA-binding transcriptional regulator compare
ECD_02206 -0.9 -1.9 NADH:ubiquinone oxidoreductase, chain I compare
ECD_03507 -0.9 -3.0 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase compare
ECD_03898 -0.9 -2.7 extracellular polysaccharide production threonine-rich protein compare
ECD_02508 -0.9 -1.4 tmRNA-binding trans-translation protein compare
ECD_00695 -0.9 -1.3 putative inner membrane protein in cydABX-ybgE operon compare
ECD_04092 -0.9 -6.7 translocation and assembly module for autotransporter export, inner membrane subunit compare
ECD_01167 -0.9 -1.4 murein tetrapeptide carboxypeptidase; LD-carboxypeptidase A compare
ECD_00081 -0.9 -2.9 transcriptional repressor-activator for carbon metabolism compare
ECD_02539 -0.9 -4.8 transcriptional repressor of microcin B17 synthesis and multidrug efflux compare
ECD_00322 -0.9 -1.2 putative transcriptional regulator compare
ECD_03241 -0.8 -3.3 3-dehydroquinate synthase compare
ECD_02525 -0.8 -2.6 DNA binding protein, nucleoid-associated compare
ECD_03610 -0.8 -2.5 phosphate ABC transporter permease compare
ECD_01818 -0.8 -1.0 extracellular Colicin M immunity family protein compare
ECD_02738 -0.8 -1.7 2-octaprenylphenol hydroxylase, FAD-dependent compare
ECD_02198 -0.8 -3.3 DUF1877 family protein compare
ECD_01589 -0.8 -1.3 transcriptional repressor of Mal regulon compare
ECD_02628 -0.8 -2.6 antitoxin of the ChpA-ChpR toxin-antitoxin system compare
ECD_02459 -0.8 -1.5 gap repair protein compare
ECD_01253 -0.8 -2.1 aconitate hydratase 1; aconitase A compare
ECD_00142 -0.8 -3.3 poly(A) polymerase compare
ECD_01084 -0.8 -3.0 DUF177 family protein compare
ECD_01960 -0.8 -2.1 putative acyl transferase compare
ECD_01080 -0.8 -2.1 endoribonuclease; RNA-binding protein compare
ECD_03039 -0.8 -5.5 putative EptAB family phosphoethanolamine transferase, inner membrane protein compare
ECD_03671 -0.8 -1.3 TDP-Fuc4NAc:lipidIIFuc4NAc transferase compare
ECD_00554 -0.8 -2.0 regulator of length of O-antigen component of lipopolysaccharide chains compare
ECD_02091 -0.8 -1.8 ribonucleoside hydrolase 2 compare
ECD_00109 -0.7 -3.7 1,6-anhydro-N-acetylmuramyl-L-alanine amidase, Zn-dependent; murein amidase compare
ECD_00940 -0.7 -1.3 aliphatic sulfonate ABC transporter periplasmic binding protein compare
ECD_02919 -0.7 -1.0 motility and biofilm regulator compare
ECD_02351 -0.7 -2.6 RmlC-like cupin domain protein compare
ECD_02048 -0.7 -1.9 putative hexameric AAA+ MoxR family ATPase compare
ECD_02775 -0.7 -4.8 DNA-specific endonuclease I compare
ECD_02456 -0.7 -1.0 putative 4Fe-4S cluster-containing protein compare
ECD_03733 -0.7 -3.8 transcription antitermination protein compare
ECD_00808 -0.7 -2.6 undecaprenyl pyrophosphate phosphatase compare
ECD_00333 -0.7 -3.1 pyrroline-5-carboxylate reductase, NAD(P)-binding compare
ECD_02463 -0.7 -2.1 back-translocating elongation factor EF4, GTPase compare
ECD_02410 -0.7 -0.8 multifunctional nucleoside diphosphate kinase and apyrimidinic endonuclease and 3'-phosphodiesterase compare
ECD_03557 -0.7 -5.4 multidrug efflux system protein compare
ECD_03756 -0.7 -4.7 GTP-binding protein compare
ECD_01835 -0.7 -0.8 UPF0082 family protein compare
ECD_03985 -0.7 -3.6 lipid A phosphoethanolamine transferase compare
ECD_00938 -0.7 -1.7 aliphatic sulfonate ABC transporter permease compare
ECD_01859 -0.7 -2.5 fused chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY: sensory histidine kinase/signal sensing protein compare
ECD_02506 -0.7 -3.1 UPF0125 family protein compare
ECD_04293 -0.7 -1.6 inhibitor of glucose uptake compare
ECD_04102 -0.7 -3.1 ribosome-associated UPF0307 family protein compare
ECD_00836 -0.7 -0.8 putative Regulatory protein compare
ECD_00358 -0.7 -2.4 HNH nuclease family protein compare
ECD_01624 -0.7 -1.9 glutaredoxin-4 compare
ECD_01472 -0.7 -1.5 autoinducer 2 import system permease protein compare
ECD_01195 -0.7 -0.9 cation transport regulator compare
ECD_03801 -0.7 -3.9 6-phosphofructokinase I compare
ECD_00889 -0.6 -1.3 leucyl/phenylalanyl-tRNA-protein transferase compare
ECD_03096 -0.6 -1.8 malate dehydrogenase, NAD(P)-binding compare
ECD_00791 -0.6 -1.9 putative pyruvate formate lyase activating enzyme compare
ECD_01826 -0.6 -1.1 myristoyl-acyl carrier protein (ACP)-dependent acyltransferase compare
ECD_01435 -0.6 -1.4 putative DNA-binding transcriptional regulator compare
ECD_01645 -0.6 -1.2 pyruvate kinase I compare
ECD_02224 -0.6 -2.0 putative NUDIX hydrolase compare
ECD_02852 -0.6 -3.9 hypothetical protein compare
ECD_00502 -0.6 -1.0 DLP12 prophage; putative antitermination protein compare
ECD_00014 -0.6 -1.5 chaperone Hsp70, with co-chaperone DnaJ compare
ECD_01219 -0.6 -2.2 oligopeptide ABC transporter permease compare
ECD_01863 -0.6 -1.0 flagellar class II regulon transcriptional activator, with FlhC compare
ECD_00389 -0.6 -2.6 ATPase and specificity subunit of ClpX-ClpP ATP-dependent serine protease compare
ECD_01305 -0.6 -2.3 S9-like protein non-peptidase family protein compare
ECD_00018 -0.6 -1.8 sodium-proton antiporter compare
ECD_03837 -0.6 -2.5 putative [formate-C-acetyltransferase 2]-activating enzyme; pyruvate formate-lyase 1-activating enzyme compare
ECD_03415 -0.6 -2.4 YiaAB family inner membrane protein compare
ECD_01403 -0.6 -1.3 DUF2526 family protein compare
ECD_02135 -0.6 -1.4 ferredoxin-type protein, role in electron transfer to periplasmic nitrate reductase NapA compare
ECD_02899 -0.6 -0.8 inner membrane protein compare
ECD_04231 -0.6 -1.5 Homoprotocatechuate degradative operon repressor compare
ECD_01926 -0.6 -1.4 N-(5'-phospho-L-ribosyl-formimino)-5-amino-1- (5'-phosphoribosyl)-4-imidazolecarboxamide isomerase compare
ECD_01245 -0.6 -2.8 23S rRNA pseudouridine(2605) synthase compare
ECD_00015 -0.6 -2.4 chaperone Hsp40, DnaK co-chaperone compare
ECD_03658 -0.6 -4.5 ATP-dependent RNA helicase compare
ECD_01006 -0.6 -1.2 uncharacterized protein compare
ECD_04308 -0.6 -1.6 uncharacterized protein compare
ECD_01101 -0.6 -1.5 OM lipoprotein stimulator of MrcB transpeptidase compare
ECD_02103 -0.6 -1.2 Zn-stimulated GTPase involved in zinc homeostasis; mutants are cadmium and EDTA sensitive; Zn(2+) binding protein compare
ECD_03353 -0.6 -1.2 hypothetical protein compare
ECD_02321 -0.6 -1.7 cysteine synthase B (O-acetylserine sulfhydrolase B) compare
ECD_01307 -0.6 -1.2 murein tripeptide (L-ala-gamma-D-glutamyl-meso-DAP) transporter subunit compare
ECD_02431 -0.6 -1.8 3-phenylpropionate dioxygenase, small (beta) subunit compare
ECD_01635 -0.5 -1.4 autotransporter adhesin-related protein compare
ECD_03611 -0.5 -2.4 phosphate ABC transporter permease compare
ECD_01124 -0.5 -1.4 spermidine/putrescine ABC transporter ATPase compare
ECD_02393 -0.5 -1.2 polyphosphate kinase, component of RNA degradosome compare
ECD_04047 -0.5 -2.7 23S rRNA mG2251 2'-O-ribose methyltransferase, SAM-dependent compare
ECD_01104 -0.5 -0.9 putative UPF0227 family esterase compare
ECD_01069 -0.5 -2.1 flagellar component of cell-proximal portion of basal-body rod compare
ECD_03727 -0.5 -0.8 aerobic ubiquinone synthesis protein, SCP2 family protein compare
ECD_04096 -0.5 -3.1 galactofuranose ABC transporter periplasmic binding protein compare
ECD_01928 -0.5 -0.9 phosphoribosyl-AMP cyclohydrolase and phosphoribosyl-ATP pyrophosphatase compare
ECD_03033 -0.5 -3.6 tRNA pseudouridine synthase B: tRNA pseudouridine(55) synthase and putative tmRNA pseudouridine(342) synthase compare
ECD_02889 -0.5 -2.1 septal ring component that protects the divisome from stress; multicopy suppressor of ftsI(Ts) compare
ECD_02831 -0.5 -3.2 putative type II secretion protein GspK compare
ECD_02300 -0.5 -1.3 DUF2502 family putative periplasmic protein compare
ECD_00136 -0.5 -0.8 putative fimbrial-like adhesin protein compare
ECD_00481 -0.5 -1.0 putative periplasmic pilus chaperone compare
ECD_00393 -0.5 -0.6 periplasmic folding chaperone, has an inactive PPIase domain compare
ECD_01225 -0.5 -1.3 putative DGPF domain-containing enzyme compare
ECD_01153 -0.5 -1.0 periplasmic inhibitor of g-type lysozyme compare
ECD_01803 -0.5 -2.6 free methionine-(R)-sulfoxide reductase compare
ECD_00968 -0.5 -1.4 UPF0319 family protein compare
ECD_02968 -0.5 -1.7 DUF1469 family inner membrane protein compare
ECD_00913 -0.5 -2.5 putative peptidase-related chaperone compare
ECD_01492 -0.5 -0.6 cysteine and O-acetyl-L-serine efflux system compare
ECD_03037 -0.5 -1.3 ribosome maturation factor for 30S subunits compare
ECD_02401 -0.5 -2.2 exonuclease VII, large subunit compare
ECD_02075 -0.5 -2.3 dihydropyrimidine dehydrogenase, NADH-dependent, subunit N compare
ECD_02814 -0.5 -2.2 hypothetical protein compare
ECD_02454 -0.5 -2.2 phosphatidylglycerophosphatase C, membrane bound compare
ECD_01110 -0.5 -2.4 transcription-repair coupling factor compare
ECD_03817 -0.5 -1.4 peptidase component of the HslUV protease compare
ECD_01096 -0.5 -1.0 putative DNase compare


Specific Phenotypes

None in this experiment

For Escherichia coli BL21 in stress experiments

For stress Tailocin 264 across organisms