Experiment set11S543 for Escherichia coli BL21

Compare to:

Tailocin 256

200 most important genes:

  gene name fitness t score description  
ECD_03983 -7.6 -5.2 sensory histidine kinase in two-component regulatory system with BasR compare
ECD_03877 -7.4 -3.0 HU, DNA-binding transcriptional regulator, alpha subunit compare
ECD_02178 -6.8 -6.6 putative LPS core heptose(II)-phosphate phosphatase compare
ECD_02465 -6.8 -4.7 anti-sigma E factor, binds RseA compare
ECD_03984 -6.7 -4.7 response regulator in two-component regulatory system with BasS compare
ECD_01930 -6.4 -4.4 UDP-glucose 6-dehydrogenase compare
ECD_02183 -6.2 -4.3 4-amino-4-deoxy-L-arabinose transferase compare
ECD_02181 -6.1 -6.0 fused UDP-L-Ara4N formyltransferase/UDP-GlcA C-4'-decarboxylase compare
ECD_03118 -6.0 -4.2 tRNA-dihydrouridine synthase B compare
ECD_02524 -6.0 -3.9 DUF2892 family inner membrane rhodanese compare
ECD_00961 -6.0 -4.2 outer membrane protein A (3a compare
ECD_00061 -6.0 -10.1 RNA polymerase remodeling/recycling factor ATPase; RNA polymerase-associated, ATP-dependent RNA translocase compare
ECD_02180 -5.9 -4.1 undecaprenyl phosphate-L-Ara4FN transferase compare
ECD_02182 -5.9 -3.5 undecaprenyl phosphate-alpha-L-ara4FN deformylase compare
ECD_00392 -5.7 -4.0 HU, DNA-binding transcriptional regulator, beta subunit compare
ECD_02505 -5.7 -13.4 lipoprotein component of BamABCDE OM biogenesis complex compare
ECD_00387 -5.7 -3.9 peptidyl-prolyl cis/trans isomerase (trigger factor) compare
ECD_03039 -5.6 -5.4 putative EptAB family phosphoethanolamine transferase, inner membrane protein conserved
ECD_00413 -5.5 -3.8 multidrug efflux system protein compare
ECD_00414 -5.2 -3.6 multidrug efflux system compare
ECD_01802 -5.2 -5.0 RNA chaperone, putative ProP translation regulator compare
ECD_02179 -5.1 -8.5 uridine 5'-(beta-1-threo-pentapyranosyl-4-ulose diphosphate) aminotransferase, PLP-dependent compare
ECD_02423 -5.1 -3.5 isc operon transcriptional repressor; suf operon transcriptional activator; oxidative stress- and iron starvation-inducible; autorepressor compare
ECD_03671 -5.0 -2.4 TDP-Fuc4NAc:lipidIIFuc4NAc transferase compare
ECD_03612 -4.9 -4.7 phosphate ABC transporter periplasmic binding protein compare
ECD_03046 -4.8 -3.3 transcript cleavage factor compare
ECD_03013 -4.8 -4.7 16S rRNA C1402 2'-O-ribose methyltransferase, SAM-dependent compare
ECD_03486 -4.8 -3.3 UDP-glucose:(Glucosyl) LPS alpha1,3-glucosyltransferase WaaO compare
ECD_02443 -4.7 -3.2 serine hydroxymethyltransferase compare
ECD_02539 -4.6 -7.2 transcriptional repressor of microcin B17 synthesis and multidrug efflux compare
ECD_04362 -4.5 -1.6 hypothetical protein compare
ECD_03668 -4.5 -3.1 TDP-fucosamine acetyltransferase compare
ECD_01225 -4.5 -1.9 putative DGPF domain-containing enzyme compare
ECD_02405 -4.4 -3.5 ancillary SecYEG translocon subunit; putative anti-RcsB factor compare
ECD_03557 -4.4 -8.0 multidrug efflux system protein compare
ECD_02162 -4.2 -1.0 ferredoxin involved with ribonucleotide reductase diferric-tyrosyl radical (Y*) cofactor maintenance compare
ECD_02186 -4.2 -4.6 inactive two-component system connector protein compare
ECD_02628 -4.0 -2.7 antitoxin of the ChpA-ChpR toxin-antitoxin system compare
ECD_00629 -4.0 -4.7 tRNA-i(6)A37 methylthiotransferase compare
ECD_01601 -4.0 -1.0 SoxR iron-sulfur cluster reduction factor component; putative membrane protein of electron transport complex compare
ECD_03695 -4.0 -1.0 Magnesium and cobalt transport protein corA compare
ECD_02393 -3.9 -3.1 polyphosphate kinase, component of RNA degradosome compare
ECD_00807 -3.9 -1.0 deoxyribose-5-phosphate-inducible deoxyribose operon transcriptional repressor; repressor of nupG and tsx compare
ECD_02116 -3.9 -4.6 spermidine nucleoid-associated protein compare
ECD_02175 -3.9 -1.9 inactive PncC family protein compare
ECD_02907 -3.8 -2.6 transport channel compare
ECD_00176 -3.8 -0.9 periplasmic chaperone compare
ECD_03673 -3.8 -6.8 UDP-N-acetyl-D-mannosaminuronic acid transferase compare
ECD_02506 -3.8 -5.2 UPF0125 family protein compare
ECD_01928 -3.7 -1.6 phosphoribosyl-AMP cyclohydrolase and phosphoribosyl-ATP pyrophosphatase compare
ECD_03610 -3.7 -2.3 phosphate ABC transporter permease compare
ECD_04119 -3.7 -0.9 SopA-central-domain-like hexapeptide repeat protein compare
ECD_03756 -3.7 -7.1 GTP-binding protein compare
ECD_03571 -3.7 -0.9 DUF1375 family outer membrane protein compare
ECD_04047 -3.6 -6.5 23S rRNA mG2251 2'-O-ribose methyltransferase, SAM-dependent compare
ECD_03985 -3.6 -8.3 lipid A phosphoethanolamine transferase compare
ECD_03240 -3.5 -7.3 cell division protein that binds to the septal ring compare
ECD_00333 -3.5 -4.8 pyrroline-5-carboxylate reductase, NAD(P)-binding compare
ECD_01365 -3.5 -1.7 putative esterase compare
ECD_03898 -3.5 -2.3 extracellular polysaccharide production threonine-rich protein compare
ECD_01774 -3.5 -1.2 ribonuclease D compare
ECD_01162 -3.5 -1.5 fatty acid metabolism regulon transcriptional regulator compare
ECD_03089 -3.4 -7.0 stringent starvation protein A, phage P1 late gene activator, RNAP-associated acid-resistance protein, inactive glutathione S-transferase-like protein compare
ECD_01301 -3.4 -1.2 lipid hydroperoxide peroxidase compare
ECD_02726 -3.3 -4.0 site-specific tyrosine recombinase compare
ECD_03425 -3.3 -1.1 putative hydrogenase, 4Fe-4S ferredoxin-type component compare
ECD_00142 -3.3 -2.3 poly(A) polymerase compare
ECD_01032 -3.3 -1.7 redox enzyme maturation protein (REMP) chaperone for YcdX compare
ECD_03669 -3.3 -2.3 TDP-4-oxo-6-deoxy-D-glucose transaminase compare
ECD_03055 -3.3 -4.2 acid stress protein; putative BolA family transcriptional regulator compare
ECD_02076 -3.3 -1.1 dihydropyrimidine dehydrogenase, NADH-dependent, subunit C compare
ECD_02404 -3.3 -1.6 BamABCDE complex OM biogenesis lipoprotein compare
ECD_02889 -3.3 -4.8 septal ring component that protects the divisome from stress; multicopy suppressor of ftsI(Ts) compare
ECD_03106 -3.2 -4.9 ribonuclease G compare
ECD_01101 -3.2 -1.6 OM lipoprotein stimulator of MrcB transpeptidase compare
ECD_00940 -3.2 -1.1 aliphatic sulfonate ABC transporter periplasmic binding protein compare
ECD_00342 -3.2 -4.1 nucleoid-associated ssDNA and dsDNA binding protein; competitive inhibitor of RecA function compare
ECD_04102 -3.1 -4.6 ribosome-associated UPF0307 family protein compare
ECD_01489 -3.1 -1.8 transcriptional repressor of multiple antibiotic resistance compare
ECD_04211 -3.1 -1.4 5-methylcytosine-specific restriction enzyme McrBC, subunit McrC compare
ECD_01044 -3.0 -1.7 OPG biosynthetic transmembrane succinyltransferase compare
ECD_04088 -3.0 -5.0 DUF1107 family protein compare
ECD_00681 -3.0 -1.0 succinate dehydrogenase, membrane subunit, binds cytochrome b556 compare
ECD_02833 -3.0 -3.4 putative type II secretion protein GspI compare
ECD_00935 -2.8 -3.3 nicotinate phosphoribosyltransferase compare
ECD_04103 -2.8 -4.8 putative antibiotic peptide MccB17 maturation peptidase compare
ECD_03036 -2.8 -1.8 transcription termination/antitermination L factor compare
ECD_t00083 -2.8 -1.3 tRNA-Leu compare
ECD_03818 -2.8 -2.0 essential cell division protein compare
ECD_00506 -2.7 -1.8 DLP12 prophage; putative phage lysis protein compare
ECD_02058 -2.7 -1.5 putative ABC transporter permease compare
ECD_03659 -2.7 -0.9 thioredoxin 1 compare
ECD_02220 -2.7 -0.9 UPF0208 family inner membrane protein compare
ECD_00900 -2.6 -1.8 dimethyl sulfoxide reductase, anaerobic, subunit C compare
ECD_01960 -2.6 -1.4 putative acyl transferase compare
ECD_00896 -2.6 -3.1 recombination intermediate processing DNA-dependent ATPase compare
ECD_02331 -2.6 -2.3 porphyrinogen oxidase, cytoplasmic compare
ECD_01110 -2.5 -4.3 transcription-repair coupling factor compare
ECD_00502 -2.5 -0.9 DLP12 prophage; putative antitermination protein compare
ECD_00612 -2.5 -1.2 DUF1451 family protein compare
ECD_02310 -2.5 -1.2 DUF3820 family protein compare
ECD_01897 -2.5 -1.7 ssuEADCB/tauABCD operon transcriptional activator compare
ECD_02825 -2.5 -1.6 Pyrophosphorylase compare
ECD_01964 -2.5 -1.7 putative acyl transferase compare
ECD_01845 -2.5 -2.2 copper homeostasis protein compare
ECD_02549 -2.4 -6.5 DNA recombination and repair protein; ssDNA-dependent ATPase; synaptase; ssDNA and dsDNA binding protein; ATP-dependent homologous DNA strand exchanger; recombinase A; LexA autocleavage cofactor compare
ECD_02909 -2.4 -3.5 DUF1190 family protein compare
ECD_00081 -2.4 -1.7 transcriptional repressor-activator for carbon metabolism compare
ECD_02826 -2.4 -1.0 hypothetical protein compare
ECD_00859 -2.4 -2.0 putrescine ABC transporter periplasmic binding protein compare
ECD_03241 -2.3 -4.7 3-dehydroquinate synthase compare
ECD_02919 -2.3 -1.6 motility and biofilm regulator compare
ECD_01875 -2.3 -3.2 tyrosine transporter compare
ECD_01694 -2.3 -1.0 fructosamine kinase family protein compare
ECD_00646 -2.3 -3.1 lipoprotein compare
ECD_02899 -2.3 -1.0 inner membrane protein compare
ECD_01011 -2.3 -0.8 putative malonic semialdehyde reductase compare
ECD_01107 -2.3 -1.6 repressor for bhsA(ycfR) compare
ECD_01189 -2.3 -2.0 transglutaminase-like TPR-repeat protein compare
ECD_03350 -2.2 -0.8 arsenical resistance operon transcriptional repressor; autorepressor compare
ECD_01486 -2.2 -1.2 UPF0056 family inner membrane protein compare
ECD_02812 -2.2 -7.9 hypothetical protein compare
ECD_02946 -2.2 -1.6 evolved beta-D-galactosidase, beta subunit; cupin superfamily compare
ECD_00752 -2.2 -1.1 molybdopterin synthase, large subunit compare
ECD_02834 -2.2 -2.5 putative type II secretion protein GspH compare
ECD_01634 -2.2 -2.2 multidrug efflux system transporter compare
ECD_03242 -2.2 -1.1 shikimate kinase I compare
ECD_02463 -2.2 -3.0 back-translocating elongation factor EF4, GTPase compare
ECD_03207 -2.2 -0.9 OsmC family protein compare
ECD_03134 -2.2 -3.5 ssDNA-binding protein, function unknown compare
ECD_01773 -2.2 -1.2 putative YeaWX dioxygenase beta subunit, reductase component compare
ECD_03070 -2.1 -4.1 adaptor protein for GlmZ/GlmY sRNA decay, glucosamine-6-phosphate-regulated; NTPase compare
ECD_01635 -2.1 -2.0 autotransporter adhesin-related protein compare
ECD_01812 -2.1 -1.1 CopC family protein compare
ECD_03735 -2.1 -4.6 NAD(P)H-flavin reductase compare
ECD_00195 -2.1 -1.8 putative outer membrane protein compare
ECD_01803 -2.1 -4.5 free methionine-(R)-sulfoxide reductase compare
ECD_01830 -2.1 -1.7 zinc ABC transporter permease compare
ECD_01219 -2.1 -1.9 oligopeptide ABC transporter permease compare
ECD_01368 -2.1 -2.1 putative ATP-dependent helicase compare
ECD_02114 -2.1 -2.8 putative ATP-dependent DNA or RNA helicase compare
ECD_02774 -2.1 -2.9 Zn-dependent metalloprotease-related protein compare
ECD_02951 -2.0 -0.9 antitoxinof the HigB-HigA toxin-antitoxin system compare
ECD_03774 -2.0 -1.1 CopG family putative transcriptional regulator compare
ECD_01910 -2.0 -1.2 UPF0265 family protein compare
ECD_00230 -2.0 -1.0 hypothetical protein compare
ECD_02365 -2.0 -1.3 palmitoyl-CoA esterase activity, uncertain physiological substrate compare
ECD_00109 -2.0 -4.2 1,6-anhydro-N-acetylmuramyl-L-alanine amidase, Zn-dependent; murein amidase compare
ECD_01167 -2.0 -0.9 murein tetrapeptide carboxypeptidase; LD-carboxypeptidase A compare
ECD_03817 -2.0 -2.1 peptidase component of the HslUV protease compare
ECD_03357 -2.0 -0.7 acid-resistance protein compare
ECD_01084 -2.0 -2.0 DUF177 family protein compare
ECD_02126 -2.0 -2.7 heme export ABC transporter permease; CcmE-interacting protein compare
ECD_01064 -1.9 -1.6 putative oxidoreductase compare
ECD_00868 -1.9 -2.0 arginine transporter subunit compare
ECD_02651 -1.9 -8.5 Ribose transport system permease protein rbsC compare
ECD_02943 -1.9 -3.5 putative tRNA binding protein; putative tRNA corner chaperone compare
ECD_03093 -1.9 -1.3 DUF1043 family inner membrane-anchored protein compare
ECD_04269 -1.9 -1.7 transcriptional repressor, tryptophan-binding compare
ECD_03508 -1.9 -1.6 tRNA mG18-2'-O-methyltransferase, SAM-dependent compare
ECD_04045 -1.9 -2.9 nitric oxide-sensitive repressor for NO regulon compare
ECD_02398 -1.9 -1.1 nalidixic acid resistance protein, putative periplasmic protein compare
ECD_02835 -1.9 -6.1 putative type II secretion protein GspG compare
ECD_01873 -1.9 -2.2 ferritin iron storage protein (cytoplasmic) compare
ECD_01887 -1.9 -1.2 inner membrane heme subunit for periplasmic YedYZ reductase compare
ECD_00834 -1.9 -1.5 putative capsid scaffolding protein compare
ECD_02473 -1.8 -1.3 autonomous glycyl radical cofactor compare
ECD_03501 -1.8 -4.5 UPF0701 family protein compare
ECD_03308 -1.8 -1.1 PanD autocleavage accelerator, panothenate synthesis compare
ECD_03056 -1.8 -3.2 ABC transporter maintaining OM lipid asymmetry, cytoplasmic STAS component compare
ECD_02768 -1.8 -5.2 biosynthetic arginine decarboxylase, PLP-binding compare
ECD_02838 -1.8 -8.9 putative type II secretion protein GspD compare
ECD_02456 -1.8 -1.2 putative 4Fe-4S cluster-containing protein compare
ECD_00442 -1.8 -0.6 iron export ABC transporter permease; peroxide resistance protein compare
ECD_02857 -1.8 -0.8 hypothetical protein compare
ECD_01878 -1.8 -2.4 excinuclease UvrABC, endonuclease subunit compare
ECD_02798 -1.8 -6.3 hypothetical protein compare
ECD_02814 -1.8 -3.4 hypothetical protein compare
ECD_02548 -1.8 -1.9 regulatory protein for RecA compare
ECD_02854 -1.8 -8.9 hypothetical protein compare
ECD_02534 -1.7 -6.3 glycine betaine/proline ABC transporter permease compare
ECD_03256 -1.7 -1.2 sensory histidine kinase in two-component regulatory system with OmpR compare
ECD_03458 -1.7 -2.4 ribosome-associated DUF2810 family protein compare
ECD_02817 -1.7 -9.1 KpsU protein compare
ECD_02239 -1.7 -0.8 membrane-anchored periplasmic protein involved in septation compare
ECD_00393 -1.7 -1.4 periplasmic folding chaperone, has an inactive PPIase domain compare
ECD_01022 -1.7 -1.3 ATP-binding protein; putative PhoH family P-loop ATPase compare
ECD_01968 -1.7 -2.4 colanic acid export protein; outer membrane auxillary lipoprotein compare
ECD_00501 -1.7 -1.4 uncharacterized protein, DLP12 prophage compare
ECD_02770 -1.7 -3.9 uncharacterized protein compare
ECD_00930 -1.7 -0.9 M15A protease-related family periplasmic protein compare
ECD_01370 -1.7 -1.1 aldehyde dehydrogenase A, NAD-linked compare
ECD_03752 -1.7 -6.0 coproporphyrinogen III oxidase, SAM and NAD(P)H dependent, oxygen-independent compare
ECD_02815 -1.7 -6.8 Capsule polysaccharide export inner-membrane protein kpsE compare
ECD_02900 -1.7 -4.3 NADPH quinone reductase compare
ECD_03534 -1.7 -1.7 hypothetical protein compare
ECD_02828 -1.7 -4.4 Polysialic acid transport protein kpsM compare
ECD_03257 -1.7 -1.1 response regulator in two-component regulatory system with EnvZ compare
ECD_02297 -1.7 -0.7 putative enzyme IIB component of PTS compare
ECD_02444 -1.7 -5.4 fused nitric oxide dioxygenase/dihydropteridine reductase 2 compare


Specific Phenotypes

For 34 genes in this experiment

For stress Tailocin 256 in Escherichia coli BL21

For stress Tailocin 256 across organisms