Experiment set11IT088 for Pseudomonas putida KT2440

Compare to:

carbon source 2-Deoxy-D-glucose 100 mM

200 most important genes:

  gene name fitness t score description  
PP_1110 -5.9 -4.1 serine acetyltransferase compare
PP_4678 -5.1 -7.8 Ketol-acid reductoisomerase compare
PP_0290 -5.0 -4.9 Imidazole glycerol phosphate synthase subunit HisH compare
PP_4922 -5.0 -7.6 Phosphomethylpyrimidine synthase compare
PP_3511 -4.7 -4.6 Branched-chain-amino-acid aminotransferase compare
PP_1988 -4.7 -3.2 3-isopropylmalate dehydrogenase compare
PP_4890 -4.7 -4.5 ATP phosphoribosyltransferase regulatory subunit compare
PP_0967 -4.7 -4.5 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
PP_5097 -4.6 -7.7 homoserine O-acetyltransferase compare
PP_0293 -4.6 -2.5 Imidazole glycerol phosphate synthase subunit HisF compare
PP_1985 -4.6 -3.2 3-isopropylmalate dehydratase large subunit compare
PP_5098 -4.6 -6.2 methionine biosynthesis protein MetW compare
PP_3790 -4.5 -8.1 diaminopimelate epimerase compare
PP_0422 -4.5 -4.4 Indole-3-glycerol phosphate synthase compare
PP_1109 -4.5 -12.5 Transcriptional regulator, GntR family compare
PP_2388 -4.5 -5.3 Transporter, LysE family compare
PP_0966 -4.4 -3.1 Histidinol dehydrogenase compare
PP_5303 -4.2 -2.9 aminoacrylate/iminopropionate hydrolase/deaminase compare
PP_5155 -4.2 -4.0 D-3-phosphoglycerate dehydrogenase / alpha-ketoglutarate reductase compare
PP_0420 -4.2 -10.7 aminodeoxychorismate synthase / para-aminobenzoate synthase multi-enzyme complex compare
PP_4680 -4.1 -10.3 acetohydroxybutanoate synthase / acetolactate synthase compare
PP_1111 -4.0 -6.7 putative Synthetase compare
PP_1020 -3.8 -3.8 putative glucose-6-phosphate 1-epimerase compare
PP_2001 -3.8 -8.4 O-succinylhomoserine sulfhydrylase compare
PP_2168 -3.7 -5.7 Transaldolase compare
PP_1348 -3.7 -6.0 putative MutT/nudix family protein/thiamine-phosphate pyrophosphorylase compare
PP_5348 -3.7 -10.5 Transcriptional regulator, LysR family compare
PP_5104 -3.7 -5.6 thiazole synthase compare
PP_1088 -3.7 -5.6 Argininosuccinate synthase compare
PP_5289 -3.6 -2.5 Acetylglutamate kinase compare
PP_0362 -3.6 -12.7 Biotin synthase compare
PP_0965 -3.6 -7.5 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
PP_0417 -3.6 -14.9 Anthranilate synthase component 1 compare
PP_4679 -3.4 -3.3 acetohydroxybutanoate synthase / acetolactate synthase compare
PP_1231 -3.4 -3.3 quinolinate synthase [4Fe-4S] cluster subunit compare
PP_1995 -3.4 -4.0 N-(5'-phosphoribosyl)anthranilate isomerase compare
PP_0421 -3.3 -8.4 Anthranilate phosphoribosyltransferase compare
PP_5346 -3.3 -8.3 pyruvate carboxylase subunit B compare
PP_0735 -3.3 -1.4 molybdopterin-synthase adenylyltransferase compare
PP_5347 -3.3 -10.7 pyruvate carboxylase subunit A compare
PP_5128 -3.3 -8.8 Dihydroxy-acid dehydratase compare
PP_0291 -3.2 -4.4 conserved protein of unknown function compare
PP_1233 -3.2 -2.2 sulfurtransferase compare
PP_2371 -3.2 -2.2 Sulphite reductase hemoprotein, beta subunit compare
PP_0787 -3.1 -3.7 quinolinate phosphoribosyltransferase (decarboxylating) monomer compare
PP_0292 -3.1 -3.3 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
PP_5075 -3.0 -8.7 glutamate synthase (NADPH) beta subunit compare
PP_1079 -3.0 -2.9 Ornithine carbamoyltransferase compare
PP_1986 -2.9 -1.8 3-isopropylmalate dehydratase small subunit compare
PP_2645 -2.8 -7.9 magnesium transporter, ATP-dependent compare
PP_5076 -2.8 -15.3 L-glutamate synthase(NADPH) alpha subunit compare
PP_0289 -2.8 -5.4 Imidazoleglycerol-phosphate dehydratase compare
PP_3244 -2.8 -2.4 Magnesium transporter, MgtC family compare
PP_3376 -2.7 -4.9 putative phosphonate dehydrogenase compare
PP_5185 -2.7 -3.2 acetylglutamate kinase-like protein (regulatory domain)/amino acid N-acetyltransferase compare
PP_1328 -2.7 -1.9 Protein MraZ compare
PP_4917 -2.7 -3.2 3',5'-cyclic-nucleotide phosphodiesterase compare
PP_2714 -2.7 -6.5 Sensor histidine kinase compare
PP_2327 -2.6 -2.5 transcriptional dual regulator / CysB-O-acetyl-L-serine compare
PP_0082 -2.6 -1.8 tryptophan synthase alpha chain compare
PP_4726 -2.6 -3.0 Chaperone protein DnaJ compare
PP_0261 -2.5 -5.2 adenosine-3'(2'),5'-bisphosphate nucleotidase compare
PP_2433 -2.4 -2.9 conserved protein of unknown function compare
PP_2370 -2.4 -2.5 conserved protein of unknown function compare
PP_5015 -2.4 -1.6 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
PP_1142 -2.4 -0.7 conserved protein of unknown function compare
PP_2646 -2.4 -2.5 conserved protein of unknown function compare
PP_4909 -2.4 -2.8 phosphoserine phosphatase compare
PP_4782 -2.4 -2.8 Phosphomethylpyrimidine kinase compare
PP_1426 -2.3 -10.4 L-aspartate oxidase compare
PP_3999 -2.3 -3.1 Uroporphyrinogen-III C-methyltransferase/Precorrin-2 dehydrogenase/Sirohydrochlorin ferrochelatase compare
PP_1025 -2.2 -7.5 2-isopropylmalate synthase compare
PP_4271 -2.2 -0.7 conserved protein of unknown function compare
PP_5528 -2.2 -1.2 conserved protein of unknown function compare
PP_4684 -2.1 -4.5 conserved protein of unknown function with kinase-like domain compare
PP_2390 -2.1 -4.3 Transcriptional regulator, LysR family compare
PP_3312 -2.1 -1.6 putative Heat shock protein compare
PP_4268 -2.1 -0.9 nucleoid-associated broad specificity regulator compare
PP_3924 -2.0 -2.7 conserved protein of unknown function compare
PP_3245 -2.0 -0.8 conserved protein of unknown function compare
PP_3359 -2.0 -2.4 putative Hydroxycinnamic acid degradation regulator compare
PP_0377 -2.0 -1.4 coenzyme PQQ synthesis protein D compare
PP_1011 -1.9 -6.8 glucokinase compare
PP_2414 -1.8 -1.7 conserved exported protein of unknown function compare
PP_3241 -1.8 -0.5 conserved exported protein of unknown function compare
PP_4897 -1.8 -2.5 N-acetylmuramoyl-L-alanine amidase compare
PP_2348 -1.8 -4.1 Sensor histidine kinase compare
PP_2575 -1.8 -2.7 conserved exported protein of unknown function compare
PP_2665 -1.8 -5.5 Glycerol metabolism activator compare
PP_5320 -1.7 -5.3 two-component system DNA-binding transcriptional dual response regulator PhoB compare
PP_2496 -1.7 -3.9 conserved protein of unknown function compare
PP_0125 -1.7 -2.9 putative cytochrome c-type protein compare
PP_1012 -1.7 -3.1 DNA-binding response regulator compare
PP_2345 -1.7 -2.0 conserved exported protein of unknown function compare
PP_3365 -1.6 -1.0 Acetolactate synthase compare
PP_1390 -1.6 -3.7 conserved exported protein of unknown function compare
PP_4723 -1.6 -2.2 Carbamoyl-phosphate synthase large chain compare
PP_3034 -1.6 -2.6 putative Regulator protein compare
PP_2700 -1.6 -2.2 AhpC/TSA family protein compare
PP_1812 -1.5 -1.8 conserved protein of unknown function compare
PP_4961 -1.5 -1.0 putative Lipoprotein compare
PP_4937 -1.5 -2.8 toluene tolerance protein compare
PP_3649 -1.5 -2.7 Transcriptional regulator, GntR family compare
PP_1224 -1.4 -4.5 periplasmic subunit of the TolQRA transport system compare
PP_5648 -1.4 -2.3 conserved exported protein of unknown function compare
PP_0114 -1.4 -5.1 methionine ABC transporter ATP-binding protein compare
PP_3052 -1.4 -1.4 conserved protein of unknown function compare
PP_0607 -1.4 -3.2 putative Type IV pili biogenesis protein FimT compare
PP_2718 -1.4 -1.2 arsenic resistance transcriptional regulator compare
PP_0910 -1.4 -3.9 conserved exported protein of unknown function compare
PP_0184 -1.4 -1.3 Argininosuccinate lyase compare
PP_3919 -1.4 -3.1 conserved protein of unknown function compare
PP_4997 -1.4 -2.0 pyrimidine operon regulatory protein/uracil phosphoribosyltransferase compare
PP_1015 -1.4 -5.0 mannose/glucose ABC transporter, glucose-binding periplasmic protein compare
PP_5557 -1.4 -0.7 protein of unknown function compare
PP_1253 -1.3 -5.4 Transcriptional regulator, ArsR family compare
PP_4695 -1.3 -6.3 Sensory box histidine kinase compare
PP_2137 -1.3 -2.3 beta-ketoadipyl CoA thiolase, beta component compare
PP_4504 -1.3 -1.4 conserved exported protein of unknown function compare
PP_2328 -1.3 -1.3 Phosphoadenosine phosphosulfate reductase compare
PP_0685 -1.3 -1.2 conserved protein of unknown function compare
PP_4569 -1.3 -2.2 conserved protein of unknown function compare
PP_1068 -1.3 -1.7 glutamate / aspartate ABC transporter - ATP binding subunit compare
PP_0506 -1.2 -6.3 putative ABC efflux transporter, permease protein compare
PP_2766 -1.2 -3.3 Long-chain-fatty-acid--CoA ligase-related protein compare
PP_2054 -1.2 -2.6 putative DNA-binding transcriptional regulator compare
PP_5487 -1.2 -2.5 conserved protein of unknown function compare
PP_4482 -1.2 -1.7 Transcriptional regulator, AraC family compare
PP_1304 -1.2 -4.5 sulfate adenylyltransferase subunit 1/adenylyl-sulfate kinase compare
PP_3938 -1.2 -1.6 conserved protein of unknown function compare
PP_5628 -1.2 -1.6 conserved protein of unknown function compare
PP_4213 -1.2 -2.0 putative dipeptidase compare
PP_1063 -1.2 -4.2 DNA-binding transcriptional regulator, homocysteine-binding compare
PP_5248 -1.2 -0.9 putative hydrolase compare
PP_2978 -1.2 -2.7 conserved protein of unknown function compare
PP_5496 -1.2 -1.5 conserved exported protein of unknown function compare
PP_3808 -1.2 -1.5 Antibiotic synthesis protein MbtH compare
PP_5140 -1.2 -1.8 Transcriptional regulator, MerR family compare
PP_3110 -1.2 -1.3 protein of unknown function compare
PP_0913 -1.2 -3.5 conserved exported protein of unknown function compare
PP_3443 -1.1 -3.6 putative glyceraldehyde-3-phosphate dehydrogenase compare
PP_2969 -1.1 -2.3 putative repressor of copper utilisation proteins compare
PP_1009 -1.1 -4.3 glyceraldehyde-3-phosphate dehydrogenase compare
PP_5027 -1.1 -1.2 D-tyrosyl-tRNA(Tyr) deacylase compare
PP_2882 -1.1 -2.5 putative 2-hydroxychromene-2-carboxylate isomerase compare
PP_0120 -1.1 -4.3 putative zinc ABC transporter compare
PP_0119 -1.1 -2.5 putative zinc uptake regulation protein ZUR compare
PP_0260 -1.1 -4.3 ADP-sugar pyrophosphorylase compare
PP_5589 -1.1 -1.3 protein of unknown function containing Rhs repeat-associated core domain compare
PP_2820 -1.1 -1.2 HTH-type transcriptional regulator nfxB compare
PP_5035 -1.1 -3.4 Histidine utilization repressor compare
PP_3509 -1.1 -2.8 Glyoxalase family protein compare
PP_2416 -1.1 -1.1 putative Iron ABC transporter, ATP-binding protein compare
PP_4739 -1.1 -1.0 conserved protein of unknown function compare
PP_5007 -1.1 -1.5 Polyhydroxyalkanoate granule-associated protein GA2 compare
PP_5327 -1.1 -4.0 putative phosphate ABC transporter, permease subunit compare
PP_4832 -1.1 -1.3 Precorrin-6x reductase compare
PP_3328 -1.1 -1.8 putative Ring-cleaving dioxygenase compare
PP_1729 -1.1 -1.2 conserved protein of unknown function compare
PP_2726 -1.1 -2.7 conserved membrane protein of unknown function compare
PP_4010 -1.1 -2.8 DNA replication inhibitor compare
PP_0978 -1.1 -1.5 conserved protein of unknown function compare
PP_1045 -1.1 -1.3 Type II secretion pathway protein XcpP compare
PP_4980 -1.0 -3.7 ATP-dependent RNA helicase compare
PP_4820 -1.0 -3.4 tRNA-dihydrouridine synthase B compare
PP_0504 -1.0 -3.4 Outer membrane protein OprG compare
PP_3789 -1.0 -3.8 putative Efflux transporter compare
PP_5014 -1.0 -0.7 Phosphoribosyl-AMP cyclohydrolase compare
PP_2976 -1.0 -0.4 putative transposase compare
PP_4060 -1.0 -5.9 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase compare
PP_1764 -1.0 -2.3 Phosphoglycolate phosphatase 2 compare
PP_2309 -1.0 -0.9 conserved protein of unknown function compare
PP_1261 -1.0 -0.9 2-ketoaldonate reductase / hydroxypyruvate/glyoxylate reductase compare
PP_2016 -1.0 -1.6 conserved protein of unknown function compare
PP_t10 -1.0 -1.2 tRNA-Pro compare
PP_5525 -1.0 -2.0 conserved exported protein of unknown function compare
PP_2307 -1.0 -1.7 conserved protein of unknown function compare
PP_3767 -1.0 -4.2 conserved protein of unknown function compare
PP_5545 -1.0 -2.7 protein of unknown function compare
PP_3197 -1.0 -1.6 Glyoxalase family protein compare
PP_4196 -1.0 -2.5 conserved exported protein of unknown function compare
PP_0834 -1.0 -0.8 Sec translocation complex subunit YajC compare
PP_3065 -1.0 -3.8 Pyocin R2_PP, tail formation compare
PP_1021 -1.0 -3.1 DNA-binding transcriptional regulator compare
PP_0878 -1.0 -2.7 dipeptide ABC transporter, binding subunit compare
PP_0949 -1.0 -3.0 putative ATP-binding protein UPF0042 compare
PP_0610 -1.0 -1.4 conserved exported protein of unknown function compare
PP_2018 -0.9 -2.3 adhesin-associated BNR repeat protein (from data) compare
PP_1550 -0.9 -1.8 Transcriptional regulator, Cro/CI family compare
PP_5552 -0.9 -0.7 conserved protein of unknown function compare
PP_4045 -0.9 -1.1 conserved protein of unknown function compare
PP_2546 -0.9 -3.0 conserved membrane protein of unknown function compare
PP_2772 -0.9 -2.0 putative Monooxygenase compare
PP_3773 -0.9 -1.5 conserved protein of unknown function compare
PP_5580 -0.9 -1.0 protein of unknown function compare
PP_3902 -0.9 -0.9 conserved protein of unknown function compare
PP_5030 -0.9 -2.6 Imidazolonepropionase compare
PP_4317 -0.9 -1.2 conserved protein of unknown function compare
PP_3496 -0.9 -2.1 Endoribonuclease L-PSP compare
PP_3048 -0.9 -1.6 conserved protein of unknown function compare


Specific Phenotypes

For 4 genes in this experiment

For carbon source 2-Deoxy-D-glucose in Pseudomonas putida KT2440

For carbon source 2-Deoxy-D-glucose across organisms